Relative Lack (relative + lack)

Distribution by Scientific Domains


Selected Abstracts


Evaluative mediation: In search of practice competencies

CONFLICT RESOLUTION QUARTERLY, Issue 2 2009
Dorothy J. Della Noce
Although there is no shortage of literature on why mediators should be allowed to give evaluations and why parties in dispute allegedly want and need evaluations, there is a relative lack of empirical literature on the subject of what exactly qualifies as competent evaluative mediation practice. The author reviews existing literature to formulate a description of the behaviors that would be considered competent in evaluative mediation practice, and to open a discussion of the implications of these findings for such contemporary fieldwide conversations as defining quality mediation, establishing performance-based competency standards, distinguishing among approaches to practice, and exploring the relationship between underlying values and practice approaches. [source]


Periorbital Reconstruction with Adjacent-Tissue Skin Grafts

DERMATOLOGIC SURGERY, Issue 12 2005
Andrew J. Kaufman MD
Background. Reconstruction in the periorbital area is challenging owing to the complex function of the eye, relative lack of adjacent loose tissue, free anatomic margin, central facial location, and the need to maintain symmetry with the contralateral eye. Reconstructive options risk crossing anatomic margins, deviation of the lid margin (ectropion), persistent lymphedema, and repair with skin of dissimilar color, texture, and thickness. Objective. The purpose was to describe a reconstructive option that would avoid crossing cosmetic units or subunits, minimize the risk of ectropion, repair with tissue of similar surface characteristics, and maintain function and symmetry with the contralateral side. Methods. The adjacent-tissue skin graft provides closure in cosmetic units and subunits, avoids tension on the lid margin, and provides similar skin for repair. The procedure is demonstrated by graphic and photographic examples. Results. The procedure provides for esthetic repair of the periorbital area and minimizes the risk of ectropion, lymphedema, asymmetry, and dysfunction of the lids and lacrimal system. Conclusion. Adjacent-tissue skin grafts are a useful alternative for reconstruction of partial-thickness defects on the eyelid and periorbital area. ANDREW J. KAUFMAN, MD, HAS INDICATED NO SIGNIFICANT INTEREST WITH COMMERCIAL SUPPORTERS. [source]


Roads to Poverty Reduction?

DEVELOPMENT POLICY REVIEW, Issue 4 2008
Exploring Rural Roads' Impact on Mobility in Africa
Within current poverty reduction programmes, focus on the social-welfare millennium development goals is widening to embrace a concern with infrastructural investment, particularly for remote areas. The previously popular assumption that rural disadvantage can be remedied by road-building is resurfacing. Using survey data from Ethiopia, Zambia and Vietnam, this article explores how effective such investment is in addressing mobility and social-service accessibility in rural areas. The findings indicate that, in extremely remote areas, road improvements may catalyse the expansion of social-service provision, as evidenced in Ethiopia. However, given the poor's relative lack of motor vehicles and ability to pay for public transport, they are, by no means, a sufficient condition for enhancing the mobility of the rural poor. [source]


Comparative growth in the postnatal skull of the extant North American turtle Pseudemys texana (Testudinoidea: Emydidae)

ACTA ZOOLOGICA, Issue 2 2008
Gabe S. Bever
Abstract Bever, G.S. 2007. Comparative growth in the postnatal skull of the extant North American turtle Pseudemys texana (Testudinoidea: Emydidae). ,Acta Zoologica (Stockholm) 88: 000,000 Postnatal growth is one of the many aspects of developmental morphology that remains distinctly understudied in reptiles. Variation and ontogenetic scaling within the skull of the extant emydid turtle, Pseudemys texana is described based on 25 continuous characters. Results indicate that skull shape in this species changes little during postnatal growth relative to the only cryptodire taxa for which comparable datasets are available (Apalone ferox and Sternotherus odoratus). This relative lack of change results in the paedomorphic retention of a largely juvenile appearance in the adult form of P. texana. The skulls of males and females, despite the presence of distinct sexual dimorphism in size, grow with similar scaling patterns, and the few observed differences appear to reflect alteration of the male growth trajectory. Comparisons with A. ferox and S. odoratus reveal a number of similarities and differences that are here interpreted within a phylogenetic context. These preliminary hypotheses constitute predictive statements that phylogenetically bracket the majority of extant cryptodire species and provide baseline comparative data that are necessary for the future recognition of apomorphic transformations. Plasticity of ontogenetic scaling as a response to the homeostatic needs and behaviour of individuals commonly is evoked as a limitation of ontogenetic scaling as a means to inform phylogenetic studies. These evocations are largely unfounded considering that variability itself can evolve and thus be phylogenetically informative. [source]


Electrochemistry at High Pressures: A Review

ELECTROANALYSIS, Issue 10 2004
Debora Giovanelli
Abstract High pressure electrochemical studies are potentially dangerous and less immediately implemented than conventional investigations. Technical obstacles related to properties of the working electrode material, preparation of its surface, availability of suitable reference electrodes, and the need for specially designed high pressure equipment and cells may account for the relative lack of experimental data on electrochemistry at high pressures. However, despite the stringent requirements for system and equipment stability, significant developments have been made in recent years and the combination of electrochemical methods with high hydrostatic pressure has provided useful insights into the thermodynamics, kinetics, and other physico-chemical characteristics of a wide range of redox reactions. In addition to fundamental information, high pressure electrochemistry has also lead to a better understanding of a variety of processes under non-classical conditions with potential applications in today's industrial environment from extraction and electrosynthesis in supercritical fluids to measurement of the pH at the bottom of the ocean. The purpose of this article is to detail the experimental pressurizing apparatus for electroanalytical measurements at high pressures and to review the relevant literature on the effect of pressure on electrode processes and on the properties of aqueous electrolyte solutions. [source]


360-degree Feedback: Possibilities for Assessment of the ACGME Core Competencies for Emergency Medicine Residents

ACADEMIC EMERGENCY MEDICINE, Issue 11 2002
Kevin G. Rodgers MD
The Accreditation Council for Graduate Medical Education (ACGME) has challenged residency programs to provide documentation via outcomes assessment that all residents have successfully mastered the six core competencies. A variety of assessment "tools" has been identified by the ACGME for outcomes assessment determination. Although rarely cited in the medical literature, 360-degree feedback is currently in widespread use in the business sector. This tool provides timely, consolidated feedback from sources in the resident's sphere of influence (emergency medicine faculty, emergency medicine residents, off-service residents and faculty, nurses, ancillary personnel, patients, out-of-hospital care providers, and a self-assessment). This is a significant deviation from both the peer review process and the resident review process that almost exclusively use physicians as raters. Because of its relative lack of development, utilization, and validation as a method of resident assessment in graduate medical education, a great opportunity exists to develop the 360-degree feedback tool for resident assessment. [source]


LEON GOLDSTEIN AND THE EPISTEMOLOGY OF HISTORICAL KNOWING,

HISTORY AND THEORY, Issue 2 2006
LUKE O'SULLIVAN
ABSTRACT Leon Goldstein's critical philosophy of history has suffered a relative lack of attention, but it is the outcome of an unusual story. He reached conclusions about the autonomy of the discipline of history similar to those of R. G. Collingwood and Michael Oakeshott, but he did so from within the Anglo-American analytic style of philosophy that had little tradition of discussing such matters. Initially, Goldstein attempted to apply a positivistic epistemology derived from Hempel's philosophy of natural science to historical knowledge, but gradually (and partly thanks to his interest in Collingwood) formulated an anti-realistic epistemology that firmly distinguished historical knowledge of the past not only from the scientific perspective but also from fictional and common-sense attitudes to the past. Among his achievements were theories of the distinctive nature of historical evidence and historical propositions, of the constructed character of historical events, and of the relationship between historical research and contemporary culture. Taken together, his ideas merit inclusion among the most important twentieth-century contributions to the problem of historical knowledge. [source]


Paediatric dentistry experience of the first cohort of students to graduate from Dublin Dental School and Hospital under the new curriculum

INTERNATIONAL JOURNAL OF PAEDIATRIC DENTISTRY, Issue 6 2004
D. FINUCANE
Summary. Aim., To assess undergraduate clinical experience in Paediatric Dentistry in students graduating under a new curriculum. Methods., An audit using logbooks completed by 34 students for all patients for whom they had provided treatment in the university paediatric dentistry clinic. Results., A total of 177 child patients had received treatment from the students, age range 2,8 years. Students had performed an average of 13 restorative techniques. Sixty-eight percent had provided stainless steel crowns and 71% at least one pulpotomy for a primary tooth. All students had provided fissure sealants. Eighteen had carried out extractions and 8 had provided treatment for fractured incisors on this clinic. Conclusions., The cohort of students included had a wide range of experience of paediatric dentistry which compared favourably with accepted guidelines. A relative lack of experience of dental extractions currently remains a problem. [source]


Social security for China's rural aged: a proposal based on a universal non-contributory pension

INTERNATIONAL JOURNAL OF SOCIAL WELFARE, Issue 2 2010
Yinan Yang
Yang Y, Williamson JB, Shen C. Social security for China's rural aged: a proposal based on a universal non-contributory pension Int J Soc Welfare 2010: 19: 236,245 © 2009 The Author(s), Journal compilation © 2009 Blackwell Publishing Ltd and the International Journal of Social Welfare. China's relative lack of social security coverage for rural elders exacerbates the already severe rural,urban economic disparity, slows the rate of rural poverty reduction, and raises social justice concerns. Our analysis draws on evidence from a number of sources including interviews with experts on China, Chinese government documents, Chinese newspaper accounts, and other sources from other countries. Based on our analysis of what has been tried in other countries and the current situation in rural China, we offer some suggestions for Chinese policy makers. We suggest that, for rural China, a universal non-contributory old-age pension deserves serious consideration, and refer to our proposed model as a Rural Old-Age Social Pension. It will reduce the level of poverty in rural areas and the degree of income inequality between rural and urban areas while simultaneously promoting social and political stability. [source]


The Transnational Capitalist Class and Contemporary Architecture in Globalizing Cities

INTERNATIONAL JOURNAL OF URBAN AND REGIONAL RESEARCH, Issue 3 2005
LESLIE SKLAIR
The focus of this article is on the role of the transnational capitalist class (TCC) in and around architecture in the production and marketing of iconic buildings and spaces, in global or world cities. The TCC is conceptualized in terms of four fractions: (1) Those who own and/or and control the major transnational corporations and their local affiliates (corporate fraction). In architecture these are the major architectural, architecture-engineering and architecture-developer-real estate firms. In comparison with the major global consumer goods, energy and financial corporations the revenues of the biggest firms in the architecture industry are quite small. However, their importance for the built environment and their cultural importance, especially in cities, far outweighs their relative lack of financial and corporate muscle. (2) Globalizing politicians and bureaucrats (state fraction). These are the politicians and bureaucrats at all levels of administrative power and responsibility who actually decide what gets built where, and how changes to the built environment are regulated. (3) Globalizing professionals (technical fraction). The members of this fraction range from the leading technicians centrally involved in the structural features of new building to those responsible for the education of students and the public in architecture. (4) Merchants and media (consumerist fraction). These are the people who are responsible for the marketing of architecture in all its manifestations. (There is obviously some overlap between the membership of these fractions.). My conclusion is that many global and aspiring global cities have looked to iconic architecture as a prime strategy of urban intervention, often in the context of rehabilitation of depressed areas. The attempt to identify the agents most responsible for this transformation, namely the TCC, and to explain how they operate, suggests that deliberately iconic architecture is becoming a global phenomenon, specifically a central urban manifestation of the culture-ideology of consumerism. L'article porte sur la classe capitaliste transnationale (TCC) au sein et à la périphérie de l'architecture, et sur son rôle dans la production et la commercialisation de constructions et espaces iconiques dans les villes mondiales ou planétaires. Cette classe se conceptualise en quatre fractions: (1) Ceux qui détiennent et/ou contrôlent les principaux groupes transnationaux et leurs sociétés affiliées locales (fraction économique): En architecture, il existe de grands cabinets d'architecture, d'ingénierie en architecture et d'architectes promoteurs immobiliers. Par rapport aux grosses sociétés multinationales de la finance, de l'énergie ou des biens de consommation, les recettes des plus importants cabinets sont assez faibles; pourtant, leur place dans l'environnement construit et la culture, notamment en milieu urbain, compensent largement leur impact relativement mince sur le plan financier et économique. (2) Les acteurs politiques et bureaucratiques de la mondialisation (fraction étatique): Il s'agit des politicients et bureaucrates à tous les niveaux de responsabilié et de pouvoir administratifs qui décident effectivement de ce qui est construit et où, ainsi que de la régulation des changements apportés à l'environnement construit. (3) Les acteurs professionnels de la mondialisation (fraction technique): Leur diversité va des techniciens de renom, surtout impliqués dans les caractéristiques structurelles des nouveaux bâtiments, à ceux qui sont chargés d'enseigner l'architecture aux étudiants et d'éduquer le public. (4) Marchands et médias (fraction consumériste): Ce sont les personnes responsables de la commercialisation de l'architecture dans toutes ses manifestations. Ces quatre fractions présentent bien sûr des intersections. On peut déduire que bon nombre de villes planétaires , ou aspirant à le devenir , ont opté pour une architecture iconique comme première stratégie d'intervention urbaine, souvent dans un contexte de réhabilitation de zones en déclin. Identifier les principaux agents responsables de cette transformation (la TCC) et expliquer leur mode de fonctionnement conduit à suggérer qu'une architecture délibérément iconique devient un phénomène mondial, plus précisément une manifestation urbaine essentielle de l'idéologie-culture du consumérisme. [source]


Do Expert Informational Intermediaries Add Value?

JOURNAL OF ACCOUNTING RESEARCH, Issue 4 2003
Evidence from Auditors in Microcap Initial Public Offerings
Do expert informational intermediaries add value? We address this question by examining the informativeness of the audit report contained in the prospectus associated with a firm's initial public offering (IPO). At the time of the IPO, there is a relative lack of information to facilitate the establishment of equity values, suggesting that the information provided by outside "experts" (e.g., auditors, underwriters) is particularly important. In this article we study small, non-venture-backed IPOs, a segment of the market with the poorest long-run performance and where the prestigious audit firm is often the sole (if any) expert present. We find that the pre-IPO opinions of larger auditors are more predictive of post-IPO negative stock delistings. Of particular note, the opinions of the national-tiered firms are comparably predictive to those of the Big 6, though this finding emerges only after we consider the selectivity-based differences in the clients that hire these national firms. Our findings also indicate that, for larger auditors the presence of a pre-IPO going-concern opinion is more strongly associated with first-year stock returns and that larger auditors are more likely to give such opinions to their distressed clients. Overall, we address a deficiency in the literature relating to "the paucity of evidence on the value of auditor opinions to investors" (Healy and Palepu [ 2001 p. 415]). [source]


Strategies to reduce the brightness reversion of industrial ECF bleached Eucalyptus globulus kraft pulp

JOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 3 2008
Isabel M. C. L. Sêco
Abstract BACKGROUND: Brightness stability is a key property of bleached chemical pulps and is primarily determined by wood species and bleaching process conditions. Eucalyptus globulus is becoming a very important raw material for hardwood pulp production. In spite of this importance, there is a relative lack of systematic studies in the literature dealing with the subject. This research aims to study the effect of some of the foremost bleaching parameters of a DEDD bleaching sequence as well as the effect of a final P stage (DEDP instead of DEDD) in the brightness stability of bleached E. globulus kraft pulps. RESULTS: The increase of the D0 stage temperature from 55 °C to 90 °C caused an increase in brightness stability. Increasing the ClO2 charges from 2.8% to 3.2% also improved significantly the brightness stability. A high H2SO4 charge in the D0 stage (10 kg tonne,1 pulp) diminished the brightness stability. The combination of H2O2 addition to the E stage and ClO2 reduction in the two final D stages does not affect brightness reversion. Raising the D2 stage temperature from 65 °C to 82 °C decreased the brightness reversion, while an increase was obtained when the temperature rose above 82 °C. Substitution of the last ClO2 stage in the DEDD sequence by a H2O2 stage (DEDP) significantly reduced the brightness reversion. CONCLUSION: For an existing pulp mill in which the implementation of new technologies to improve brightness reversion is considered, the results obtained showed that brightness stability can be improved without any significant capital investment. Copyright © 2007 Society of Chemical Industry [source]


Morphology of the prometamorphic larva of the spadefoot toad, Scaphiopus intermontanus (Anura: Pelobatidae), with an emphasis on the lateral line system and mouthparts

JOURNAL OF MORPHOLOGY, Issue 2 2002
John A. Hall
Abstract We provide a detailed description of the larval morphology of the Great Basin spadefoot toad (Scaphiopus intermontanus), a species with documented morphological variability in larval structures associated with feeding. We based our findings on laboratory-raised individuals fed a herbivorous diet. We characterized the morphology of the prometamorphic larva (limited to developmental stages 37 and 38) and then related our findings to the larval ecology of the species. Based on its morphology, such as slightly depressed body, dorsally positioned eyes, anteroventrally oriented oral disc, intermediate tail fin height and slightly attenuated tail tip, relative lack of ventral neuromasts (compared to Xenopus laevis), and pigmentation banding patterns, and habits, such as selection of breeding sites by adults and larval foraging behavior, S. intermontanus can be characterized best as belonging to a (lentic-) benthic guild of anuran larvae. Nevertheless, the larvae are capable of occupying a broader array of ecological niches. Because we characterized individuals raised on a herbivorous diet, our morphological descriptions apply only to the herbivorous S. intermontanus larva (and perhaps to those larvae that are dietary generalists and may feed carnivorously only infrequently). Our findings can serve as a baseline for future morphological and developmental comparisons with the carnivorous morphological variant of this species. J. Morphol. 252:114,130, 2002. © 2002 Wiley-Liss, Inc. [source]


A species-level phylogenetic supertree of marsupials

JOURNAL OF ZOOLOGY, Issue 1 2004
Marcel Cardillo
Abstract Comparative studies require information on phylogenetic relationships, but complete species-level phylogenetic trees of large clades are difficult to produce. One solution is to combine algorithmically many small trees into a single, larger supertree. Here we present a virtually complete, species-level phylogeny of the marsupials (Mammalia: Metatheria), built by combining 158 phylogenetic estimates published since 1980, using matrix representation with parsimony. The supertree is well resolved overall (73.7%), although resolution varies across the tree, indicating variation both in the amount of phylogenetic information available for different taxa, and the degree of conflict among phylogenetic estimates. In particular, the supertree shows poor resolution within the American marsupial taxa, reflecting a relative lack of systematic effort compared to the Australasian taxa. There are also important differences in supertrees based on source phylogenies published before 1995 and those published more recently. The supertree can be viewed as a meta-analysis of marsupial phylogenetic studies, and should be useful as a framework for phylogenetically explicit comparative studies of marsupial evolution and ecology. [source]


Ethnicity and Sociolinguistic Variation in San Francisco

LINGUISTICS & LANGUAGE COMPASS (ELECTRONIC), Issue 7 2010
Lauren Hall-Lew
California's San Francisco Bay Area has long been one of the most ethnically diverse areas of the United States, and ethnicity is an integral aspect of any research on language use in the region. This article gives a brief social history of San Francisco with respect to settlement patterns since the 1850s' gold rush, paying particular attention to Chinese Americans, who are argued to play an especially distinctive role in the city's history and current social landscape. This article also reviews the sociolinguistic research on language and ethnicity in and around San Francisco, with a focus on studies on variation and change in English, noting the relative lack of attention to Asian American ethnicities and calling for increased scholarship on the linguistic construction of Asian identities in the San Francisco area. [source]


Optometrists' examination and referral practices for patients presenting with flashes and floaters

OPHTHALMIC AND PHYSIOLOGICAL OPTICS, Issue 3 2002
A. Alwitry
Introduction:,Patients experiencing flashes and floaters commonly present to their optometrist. Some of these patients may have significant pathology, yet there is a great deal of variability with regard to examination technique and referral practice. Methods:,A questionnaire survey was undertaken to determine the current management of patients presenting to their optometrist with flashes and floaters. All practising community optometrists within Southern Derbyshire received a questionnaire and 74 (56.9%) completed replies were received. Results:,Optometrists estimated that an average of 14 patients per month per optometrist presented with symptoms of flashes and/or floaters. Mydriasis was utilised routinely for examination in approximately half of the patients. Mean relative confidence was 2.0 at identifying a vitreous haemorrhage and 6.5 for vitreous pigment (complete confidence = 0, complete lack of confidence = 10). Eight percent of responders were unfamiliar with the clinical sign of vitreous pigment, and 17% identifying this sign did not refer all such patients to the hospital services. Conclusions:,Patients presenting to their optometrists with flashes and/or floaters make up a sizeable part of the community optometrist's workload and the management of these patients is highly variable. A large proportion of these patients are examined without mydriasis, even in the presence of various risk factors for retinal detachment. There is a relative lack of confidence amongst optometrists with regards the detection of vitreous pigment and the prognostic implications of this finding. Educational measures such as study days may help the level of understanding and heighten the appreciation of the implications of flashes and floaters and the various clinical signs encountered. [source]


Diabetic autoimmunity in infants and pre-schoolers with type 1 diabetes

PEDIATRIC DIABETES, Issue 3 2000
Eba H Hathout
The incidence of type 1 diabetes is increasing most rapidly in children under 5 yrs of age, a group where the disease appears to be more accelerated than traditional type 1 diabetes. Little is known about demographics, and markers of diabetes autoimmunity, in infants and pre-schoolers with type 1 diabetes. We report an analysis of 47 children diagnosed with type 1 diabetes prior to 5 yrs of age compared with a representative cohort (n=49) diagnosed after 5 yrs of age, and all were followed at Loma Linda University (LLU) Children's Hospital. Ethnic, familial, seasonal, and autoimmune marker characteristics are outlined. To determine the prevalence of diabetes autoimmune markers, ICA512, GAD65 and insulin autoantibodies (IAA) antibodies were measured. Children with early-onset diabetes had a significantly higher incidence of viral illness symptoms (p=0.005) and diabetic ketoacidosis (DKA; p=0.017) at the time of diagnosis. However, hemoglobin A1C (HbA1c) levels at diagnosis were significantly higher in the later-onset group (p=0.001). A honeymoon period was reported in 14.8% of children diagnosed before 5 yrs of age compared with 42.1% in those diagnosed over 5 yrs of age (p=0.038). Islet-cell antibodies (ICAs) and glutamic acid decarboxylase (GAD) antibody titers were significantly different between early- and later-onset groups. ICA titers were positive in 35.29%, and GAD in 41.38% of the early-onset group versus 70.83 and 71.74% in children with later-onset disease, (p=0.001 and 0.009, respectively). IAA titers, drawn after instituting insulin therapy, were not significantly different between the two groups. GAD and ICA512 antibody results suggest a relative lack of diabetes immune markers in infants and toddlers with new-onset diabetes. This finding, and the apparent shorter pre-clinical phase reflected in the lower HbA1c values, may indicate age-related differences in type 1 diabetes autoimmunity or the existence of non-autoimmune diabetogenic mechanisms in younger children. [source]


Diet reconstruction in antebellum Baltimore: Insights from dental microwear analysis

AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY, Issue 4 2010
Peter H. Ma
Abstract Construction in the City of Baltimore during 1996 led to the recovery of human skeletal remains dating from 1792 to 1856. Historical research indicates that the skeletal remains come from two adjacent graveyards: Christ's Church Episcopalian Cemetery and the Potters Field East. The different socioeconomic status of the internees in each cemetery suggests the possibility of marked contrasts in lifestyle, health, and diet. To shed further light on these possibilities, analyses of microscopic wear patterns on teeth, or dental microwear analyses, were undertaken. A sample from Spanish Florida was used to help interpret the results. Epoxy casts of incisor and molar teeth were placed in an SEM and photomicrographs of clean wear facets were taken. The photomicrographs were digitized using the software package Microware 4.02. Statistical analyses of rank transformed data consisted of single-factor ANOVA, followed by post hoc tests. No significant differences were found between Christ's Church and Potters Field East samples for any of the variables examined in either molar or incisor teeth. However, differences between each Baltimore sample and the La Florida samples give suggestions of possible diet differences in antebellum Baltimore. The mosaic of differences between the Baltimore and La Florida samples probably reflects the wide variety of foods available to antebellum Baltimoreans as well as the relative lack of abrasives in their diet. Am J Phys Anthropol, 2010. © 2009 Wiley-Liss, Inc. [source]


Increasing Use of the Scapula Osteocutaneous Free Flap ,

THE LARYNGOSCOPE, Issue 9 2000
Sean C. Coleman MD
Abstract Objectives To determine the appropriate use of the scapula osteocutaneous free flap (SOFF) and to document donor site morbidity. Study Design Retrospective review and prospective physical therapy evaluation. Methods A computer database of all free flap procedures performed at a single institution was created. Specific clinical and operative details from cases involving a bone flap were extracted from the database. Rates of usage of the various osteocutaneous flaps were compared over four successive 2-year intervals (1992,1999). A single physical therapist performed a structured evaluation of the donor site. Results Overall, 64 bone flap procedures were performed, of which 24 (37.5%) were SOFF procedures. The SOFF utilization has increased from 6.6% to 63.6%, while fibula and iliac crest utilization has fallen significantly. This is in part because of the greater versatility of the SOFF, with the possibility of separate skin paddles and adequate bone length. The mean cutaneous area harvested with the SOFF was 110 cm2 (range, 48,200 cm2) compared with 55.4 cm2 (range, 25,102 cm2) and 77.6 cm2 (range, 50,120 cm2) for the fibula and iliac crest, respectively. Mean bone flap lengths were 8.37, 7.65, and 10.1 cm, respectively, for the SOFF, fibula, and iliac crest. Dual skin paddles were used in 50% of the SOFF procedures versus 2.8% for the fibula flap procedures. There were no significant complications of the donor site in any patient, and there was only one flap failure (4.1%). Related to the SOFF, donor site morbidity was subjectively judged as "mild," for pain, mobility, and strength. There were no complaints of poor appearance of the donor site. Activities of daily living were judged as "not limited" or "limited a little" in the majority of patients. Objective measurements of range of motion revealed an average reduction of 1° to 12° in five different shoulder functions. Elbow and arm ranges of motion were not limited. Strength was minimally reduced in the shoulder, while the arm and forearm showed no reduction in strength. Conclusions The SOFF is a versatile osteocutaneous free flap that can be used for a multitude of reconstructive problems. This and its relative lack of significant donor site morbidity have caused its use to increase significantly. [source]


Stem cells and diabetes treatment,

APMIS, Issue 11-12 2005
OLE DRAGSBÆK MADSEN
Diabetes mellitus types 1 and 2 are characterized by absolute versus relative lack of insulin-producing , cells, respectively. Reconstitution of a functional ,-cell mass by cell therapy , using organ donor islets of Langerhans , has been demonstrated to restore euglycaemia in the absence of insulin treatment. This remarkable achievement has stimulated the search for appropriate stem cell sources from which adequate expansion and maturation of therapeutic , cells can be achieved. This recent activity is reviewed and presented with particular focus on directed differentiation from pluripotent embryonic stem cells (versus other stem/progenitor cell sources) based on knowledge from pancreatic ,-cell development and the parallel approach to controlling endogenous ,-cell neogenesis. [source]


Cryotherapy for treatment of oral lesions

AUSTRALIAN DENTAL JOURNAL, Issue 1 2006
CS Farah Senior Lecturer
Abstract Cryotherapy is the deliberate destruction of tissue by application of extreme cold. It is well received by patients due to a relative lack of discomfort, the absence of bleeding and minimal to no scarring after healing. It has many applications in oral medicine and clinical oral pathology, and is extremely useful in patients for whom surgery is contra-indicated due to either age or medical history. In this paper we outline the principles, mechanisms of action, and current applications of cryotherapy in the treatment of oral lesions, and present some clinical cases. [source]


Testing long-term patterns of basin sedimentation by detrital zircon geochronology, Centralian Superbasin, Australia

BASIN RESEARCH, Issue 3 2007
D. W. Maidment
ABSTRACT Detrital zircon geochronology of Neoproterozoic to Devonian sedimentary rocks from the Georgina and Amadeus basins has been used to track changes in provenance that reflect the development and inversion of the former Australian Superbasin. Through much of the Neoproterozoic, sediments appear to have been predominantly derived from local sources in the Arunta and Musgrave inliers. Close similarities between the detrital age signatures of late Neoproterozoic sedimentary rocks in the two basins suggests that they were contiguous at this time. A dominant population of 1.2,1.0 Ga zircon in Early Cambrian sediments of the Amadeus Basin reflects the uplift of the Musgrave Inlier during the Petermann Orogeny between 560 and 520 Ma, which shed a large volume of detritus northwards into the Amadeus Basin. Early Cambrian sedimentary rocks in the Georgina Basin have a much smaller proportion of 1.2,1.0 Ga detritus, possibly due to the formation of sub-basins along the northern margin of the Amadeus Basin which might have acted as a barrier to sediment transfer. An influx of 0.6,0.5 Ga zircon towards the end of the Cambrian coincides with the transgression of the Larapintine Sea across central Australia, possibly as a result of intracratonic rifting. Detrital zircon age spectra of sedimentary rocks deposited within this epicontinental sea are very similar to those of coeval sedimentary rocks from the Pacific Gondwana margin, implying that sediment was transported into central Australia from the eastern continental margin. The remarkably consistent ,Pacific Gondwana' signature of Cambro-Ordovician sediments in central and eastern Australia reflects a distal source, possibly from east Antarctica or the East African Orogen. The peak of the marine incursion into central Australia in the early to mid Ordovician coincides with granulite-facies metamorphism at mid-crustal depths between the Amadeus and Georgina basins (the Larapinta Event). The presence of the epicontinental sea, the relative lack of a local basement zircon component in Cambro-Ordovician sedimentary rocks and their maturity suggest that metamorphism was not accompanied by mountain building, consistent with an extensional or transtensional setting for this tectonism. Sediments deposited at ,435,405 and ,365 Ma during the Alice Springs Orogeny have detrital age signatures similar to those of Cambro-Ordovician sedimentary rocks, reflecting uplift and reworking of the older succession into narrow foreland basins adjacent to the orogen. [source]


An Assessment of the Faculty Development Needs of Junior Clinical Faculty in Emergency Medicine

ACADEMIC EMERGENCY MEDICINE, Issue 7 2008
Heather Farley MD
Abstract Objectives:, Academic physicians must be able to access the resources necessary to support their ongoing professional development and meet requirements for continued academic advancement. The authors sought to determine the self-perceived career development needs of junior clinical faculty in emergency medicine (EM) and the availability of educational resources to meet those needs. Methods:, An educational "needs assessment" survey was distributed to 954 American College of Emergency Physicians (ACEP) members listed in the ACEP database as being faculty at EM residency programs in the United States and having graduated from an EM residency within the past 7 years. Respondents were asked to rank the importance of 22 areas of faculty development to their own professional growth and then to indicate whether educational resources in each area were available to them. Respondents were also asked to note the educational formats they prefer. A search for currently available resources in each topic area was undertaken and compared to the survey results. Results:, A total of 240 responses were received. Self-perceived career development needs were identified in the following areas: bedside teaching, lecture development, business skills, managerial skills, educational research, mentorship and career counseling, interpersonal skills, leadership skills, scholarly writing skills, physician wellness, and knowledge of the faculty development process. While a review of currently available educational resources revealed lectures, conferences, and online materials pertinent to most of these topics, a relative lack of resources in the areas of mentorship and physician wellness was identified. Conclusions:, Junior clinical faculty in EM perceive a lack of educational resources in a number of areas of faculty development. The academic community of EM should strive to improve awareness of and access to currently existing resources and to develop additional resources to address the area of physician wellness. The lack of mentorship in academic EM continues to be a problem in search of a solution. [source]