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Related Findings (relate + finding)
Selected AbstractsIntegrative Motivation: Changes During a Year-Long Intermediate-Level Language CourseLANGUAGE LEARNING, Issue 1 2004R. C. Gardner The socioeducational model of second Language acquisition postulates that Language learning is a dynamic process in which affective variable influence Language achievement and achievement and experiences in Language learning can influences some affective variables. Five classes of variable are emphasized: integrativeness, attitudes toward the learning situation, motivation, Language anxiety, and instrumental orientation. The present study of a 1-year intermediate-level French course reveals that some affective characteristics are more amenable to change than others, and that patterns of change over time are moderated by achievement in the course. Related findings demonstrate very few differences on the affective measures from one class section to another, and that day-to-day levels of state motivation are largely invariant, whereas state anxiety might be influenced by environmental events. [source] Innovation and collaboration in the geographic information systems (GIS) industry: evidence from Canada and the United StatesR & D MANAGEMENT, Issue 3 2000Valerie Hartung This paper examines the role of collaborative technical activity in the innovation performance of Canadian and US companies in the geographic information systems (GIS) industry. This young but rapidly growing sector produces specialised hardware and software for cartographic applications (computer mapping). Evidence from a sample of 384 companies suggests that innovation is strongly dependent upon in-house R&D. The results also suggest that a firm's propensity to operate within a collaborative network varies directly with its R&-intensity. A description of the main benefits and costs of collaboration is presented. Although there is no statistical association between innovation and the incidence of external collaboration, the evidence suggests that R&D partnerships contribute to the innovation process in a number of important ways. The key contribution lies in the speed of product commercialisation. A related finding is that collaborators tend to generate radical innovations more frequently than less successful and/or non-collaborators. [source] White matter abnormalities in children with and at risk for bipolar disorderBIPOLAR DISORDERS, Issue 8 2007Jean A Frazier Objectives:, Diffusion tensor magnetic resonance imaging (DT-MRI) assesses the integrity of white matter (WM) tracts in the brain. Children with bipolar disorder (BPD) may have WM abnormalities that precede illness onset. To more fully examine this possibility, we scanned children with DSM-IV BPD and compared them to healthy peers and children at risk for BPD (AR-BPD), defined as having a first-degree relative with the disorder. Methods:, Ten children with BPD, eight healthy controls (HC), and seven AR-BPD, similar in age, had MRI scans on a 1.5 Tesla GE scanner, including a standard DT-MRI sequence (T2-EPI) with 25 axial slices. Fractional anisotropy (FA) values were compared between groups to determine regions of significant difference (p < 0.05). Results:, Compared to HC, children with BPD had decreased FA in right and left superior frontal tracts, including the superior longitudinal fasciculus I (SLF I) and the cingulate-paracingulate WM (CG-PACWM). In addition, the BPD group had reduced FA in left orbital frontal WM and the right corpus callosum body. Compared to AR-BPD, children with BPD showed reduced FA in the right and left CG-PACWM. Both the BPD and AR-BPD groups showed reduced FA relative to HC in bilateral SLF I. Conclusions:, The bilateral SLF I finding in both the BPD and AR-BPD groups may represent a trait-based marker or endophenotype of the disorder. The finding of decreased FA in the right and left CG-PACWM in children with BPD compared to the other two groups may represent a disease-state related finding. [source] Analysis of mitochondria by capillary electrophoresis: cardiolipin levels decrease in response to carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazoneEUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, Issue 9 2010Wenfeng Zhao Abstract Cardiolipin is an important phospholipid present in the inner membrane of mitochondria. It plays a critical role in adenosine triphosphate (ATP) synthesis mediated by oxidative phosphorylation. Exposure of HepG2 cells to carbonyl cyanide 4-(trifluoromethoxy) phenylhydrazone (FCCP) caused the inhibition of ATP synthesis and the depolarization of mitochondria. Capillary electrophoresis with laser-induced fluorescence (CE-LIF) analysis of fluorescent mitochondrion-selective probe 10-N-nonyl acridine orange (NAO) labeled mitochondria was employed to in situ estimate the cardiolipin levels under FCCP-induced de-energization of mitochondria. NAO, stoichiometriclly bound to cardiolipin at a 1:1 or 2:1 molar ratio (NAO/cardiolipin), emitted green and red fluorescence, respectively. Green fluorescence was chosen for cardiolipin content analysis because it was more intense than red fluorescence. A significant decrease in the cardiolipin content, up to 11% of the control, was evident when the ATP content and mitochondrial membrane potential (MMP) correspondingly decreased. These related findings suggested that CE-LIF may provide a sensitive strategy to determine cardiolipin content in response to exposure to chemical uncouplers. This reinforces the hypothesis that alterations in ATP synthesis and MMP have a close association with cardiolipin content, which correlated tightly with mitochondrial membrane assembly and activity. [source] A latent growth-curve approach to difficult temperamentINFANT AND CHILD DEVELOPMENT, Issue 3 2007Ty Partridge A purported hallmark of temperament characteristics is that they appear very early in the course of development and are persistent across time and situation. There is, however, a small, but growing cadre of research findings that question this traditional view. It may be that temperament characteristics are not necessarily established during the first few months of development or are not stable over time. A secondary analysis of the New York Longitudinal Study (NYLS) temperament data was conducted to investigate the hypothesis that temperament has a complex developmental course over the first five years of development. A latent growth curve analysis of difficult temperament suggests that temperament development follows a non-linear trajectory. This finding, in concert with related findings, suggests the need for a broader discussion of the possible developmental processes that underlie these patterns. Copyright © 2007 John Wiley & Sons, Ltd. [source] Prevalence of penetrating disease and extraintestinal manifestations of Crohn's disease detected with CT enterographyINFLAMMATORY BOWEL DISEASES, Issue 12 2008David H. Bruining MD Abstract Background: This study was conducted to determine the prevalence of penetrating disease and extraintestinal manifestations of Crohn's disease (CD) identified by computed tomography enterography (CTE). We also sought to examine the percentage of clinically significant new noninflammatory bowel disease (IBD) related findings in these patients. Methods: We analyzed the records of 357 consecutive patients with previously diagnosed CD evaluated at our institution who underwent a CTE between August 2004 and October 2005. Radiology reports were reviewed for the presence of penetrating disease (abscess, fistula, or phlegmon) or extraintestinal IBD manifestations (nephrolithiasis, cholelithiasis, sacroiliitis, avascular necrosis, deep vein thrombosis, or primary sclerosing cholangitis). Additional non-IBD-related abnormalities were also recorded, including any mass or cystic lesion. Urgent findings were defined as those that were deemed by the radiologist or ordering physician to require medical follow-up within 3 months. Results: Of 357 patients identified (51% female) the median age was 41.6 years and median disease duration was 9.9 years. Of this cohort, 20.7% had penetrating disease (new finding in 58.1%) and 18.8% had extraintestinal IBD manifestations (new finding in 67.2%). Six patients had primary sclerosing cholangitis and portal/mesenteric vein thrombosis, respectively. In addition, 45.1% had non-IBD findings including 2 unsuspected malignancies. Most of these extraenteric non-IBD abnormalities were benign, with only 13.0% requiring urgent follow-up. Conclusions: CT enterography is a valuable diagnostic modality for detecting both penetrating disease and extraintestinal IBD manifestations. These data add to a growing body of evidence that supports the use of CTE in CD diagnostic and management algorithms. (Inflamm Bowel Dis 2008) [source] Use of three-dimensional (3-D) immersive virtual worlds in K-12 and higher education settings: A review of the researchBRITISH JOURNAL OF EDUCATIONAL TECHNOLOGY, Issue 1 2010Khe Foon Hew In this paper, we review past empirical research studies on the use of three-dimensional immersive virtual worlds in education settings such as K-12 and higher education. Three questions guided our review: (1) How are virtual worlds (eg, Active Worlds, Second Life) used by students and teachers? (2) What types of research methods have been applied? (3) What research topics have been conducted on virtual worlds in teaching and learning, as well as their related findings? Overall, we found that virtual worlds may be utilised for the following uses: (1) communication spaces, (2) simulation of space (spatial), and (3) experiential spaces (,acting' on the world). Most of the studies reviewed were descriptive and conducted in polytechnic and university settings, and past virtual world research had been most frequently carried out in the media arts and health and environment disciplines. Three main research topics were found: participants' affective domain, learning outcomes and social interaction. We conclude by summarising some major findings and discussing three limitations of previous empirical studies. Several recommendations for future research related to virtual worlds in education settings are also provided. [source] Information Technology Projects by International Logistics Services Providers: The Case of Canada's Small Customs BrokersCANADIAN JOURNAL OF ADMINISTRATIVE SCIENCES, Issue 1 2006Michael A. Haughton Abstract This study explores the motives and effects of information and communication technology (ICT) investments made by some of Canada's small customs brokers. Like other providers of support services for global supply chain operations, customs brokers have been implored to recognize the significant rewards of effectively deployed ICT. Using qualitative data on eight small Canadian customs brokers, this study determines the extent to which expectation of those rewards motivated the workers' ICT investments. Drawing on institutional theory to complement the analysis, the study finds that the motives transcend belief in ICT projects' inherent utility. This and related findings on the impact of ICT projects on the brokers, extend knowledge concerning the study of important ICT investment decisions in the context of trans-border goods movement. Résumé Cette étude examine les motifs et les effets des investissements rélisés dans la technologie de l'information et de la communication (ICT) par de petits agents en douane canadiens. Comme d'autres fournisseurs d'abonnement de maintenance des opárations de chaîne d'approvision-nements, ces agents étaient invités à identifier les récompenses considérables liées au déploiement efficace de l'ICT. À partir de données qualitatives portant sur huit agents, l'étude s'attelle à déterminer dans quelle mesure l'espérance des récompenses motive les investissements. S'inspirant de la théorie institutionnelle pour compléter l'analyse, l'étude constate que les motifs dépassent la croyance en l'utilité intrinsèque des projets ICT. Cette conclusion et l'impact des projets sur les agents, s'inscrit dans le prolongement des études sur les décisions d'investissement en ICT dans le contexte du commerce transfrontalier. [source] | |||||||||||||