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Recognition Memory (recognition + memory)
Terms modified by Recognition Memory Selected AbstractsLONG-TERM EXPOSURE TO EXTREMELY LOW-FREQUENCY MAGNETIC FIELDS IMPAIRS SPATIAL RECOGNITION MEMORY IN MICECLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, Issue 7 2008Yu Fu SUMMARY 1In the present study, we investigated the short- and long-term effects of extremely low-frequency (ELF) magnetic fields on spatial recognition memory in mice by using a two-trial recognition Y-maze that is based on the innate tendency of rodents to explore novel environments. 2Mice were exposed to 25 or 50 Hz electromagnetic fields for either 7 (short term) or 25 days (long term) and then tested in the Y-maze. 3The results indicated that neither short- nor long-term exposure to magnetic fields affected the locomotor activity of mice in the Y-maze. However, long-term exposure to 50 Hz fields reduced recognition of the novel arm. 4Our findings suggest that ELF magnetic fields impair spatial recognition memory in the Y-maze depending on the field strength and/or duration of exposure. [source] Individual Differences in Infants' Recognition of Briefly Presented Visual StimuliINFANCY, Issue 3 2001Janet E. Frick Infants' recognition memory has been shown to be related to individual differences in look duration and level of heart period variability. This study examined the effect of individual differences in these 2 measures on infants' recognition of briefly presented visual stimuli using a paired-comparison recognition-memory paradigm. A sample of 35 full-term infants was studied longitudinally at 14, 20, and 26 weeks of age. Recognition memory for briefly presented stimuli was tested in 6 experimental conditions, with delays corresponding to different heart-rate-defined phases of attention. The 20-and 26-week-old infants, and infants with high levels of heart period variability, generally showed more evidence of recognition memory for briefly presented visual stimuli. Greater evidence of recognition memory was observed when stimuli were presented during sustained attention. Infants with more mature baseline physiological responses show greater evidence of recognition memory, and stimulus and procedural factors may be more important for the study of individual differences in infant visual attention than has previously been suggested. [source] Neurocognitive functions in euthymic bipolar patientsACTA PSYCHIATRICA SCANDINAVICA, Issue 5 2009K. Jamrozinski Objective:, Meta-analytic findings support the hypothesis of specific neurocognitive deficits for bipolar patients in the domains of attention, processing speed, memory and executive functions. This study aims to show neurocognitive impairment in euthymic patients with bipolar I disorder compared with healthy controls while detailing the impact of medication side-effects or illness characteristics on neuropsychological test performance. Method:, Forty euthymic patients with bipolar I disorder were compared with 40 healthy controls in a cross-sectional design. Clinical features and neuropsychological measures of IQ, psychomotor speed, verbal fluency, learning and memory, executive functions and attention were assessed. Results:, Patients without antipsychotic drug use did not differ significantly from healthy controls in any neuropsychological measure. Yet patients treated with antipsychotics showed significant underperformance in the domains of semantic fluency, verbal learning and recognition memory as well as executive functions related to planning abilities, even when clinical features were controlled for. Conclusion:, The impact of antipsychotic medication needs to be further clarified for euthymic bipolar patients and should be considered when neuropsychological test performance is interpreted. [source] Influences of postconceptional age and postnatal experience on the development of auditory recognition memory in the newborn infantDEVELOPMENTAL PSYCHOBIOLOGY, Issue 3 2002Raye-Ann deRegnier Abstract We evaluated the effects of postconceptional age and postnatal experience on the development of neonatal auditory recognition memory. Three groups were tested: a premature newborn group (tested at 35,38 weeks postconceptional age, ,1 week old), a full-term newborn group (tested at 39,42 weeks postconceptional age, ,1 week old), and a full-term experienced group (tested at 39,42 weeks postconceptional age, >1 week old; range 8,30 days). Event-related potentials were collected while infants listened to the maternal voice alternating with a stranger's voice. Postconceptional age was correlated with the development of recognition memory for the maternal voice while there were qualitative effects of postnatal experience on latency measurements. Maturity of auditory cortical responses was not correlated with recognition memory abilities. We conclude that maturation of the recognition memory pathways is primarily a function of postconceptional age with qualitative effects of postnatal experience. Maturation of the auditory recognition memory pathway is not contingent upon maturation of the "P2" peak thought to arise from primary auditory cortex. © 2002 Wiley Periodicals, Inc. Dev Psychobiol 41: 216,225, 2002. Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/dev.10070 [source] Ketamine use, cognition and psychological wellbeing: a comparison of frequent, infrequent and ex-users with polydrug and non-using controlsADDICTION, Issue 1 2009Celia J. A. Morgan ABSTRACT Introduction Preliminary research has indicated that recreational ketamine use may be associated with marked cognitive impairments and elevated psychopathological symptoms, although no study to date has determined how these are affected by differing frequencies of use or whether they are reversible on cessation of use. In this study we aimed to determine how variations in ketamine use and abstention from prior use affect neurocognitive function and psychological wellbeing. Method We assessed a total of 150 individuals: 30 frequent ketamine users, 30 infrequent ketamine users, 30 ex-ketamine users, 30 polydrug users and 30 controls who did not use illicit drugs. Cognitive tasks included spatial working memory, pattern recognition memory, the Stockings of Cambridge (a variant of the Tower of London task), simple vigilance and verbal and category fluency. Standardized questionnaires were used to assess psychological wellbeing. Hair analysis was used to verify group membership. Results Frequent ketamine users were impaired on spatial working memory, pattern recognition memory, Stockings of Cambridge and category fluency but exhibited preserved verbal fluency and prose recall. There were no differences in the performance of the infrequent ketamine users or ex-users compared to the other groups. Frequent users showed increased delusional, dissociative and schizotypal symptoms which were also evident to a lesser extent in infrequent and ex-users. Delusional symptoms correlated positively with the amount of ketamine used currently by the frequent users. Conclusions Frequent ketamine use is associated with impairments in working memory, episodic memory and aspects of executive function as well as reduced psychological wellbeing. ,Recreational' ketamine use does not appear to be associated with distinct cognitive impairments although increased levels of delusional and dissociative symptoms were observed. As no performance decrements were observed in the ex-ketamine users, it is possible that the cognitive impairments observed in the frequent ketamine group are reversible upon cessation of ketamine use, although delusional symptoms persist. [source] Wada Memory Performance Predicts Seizure Outcome after Epilepsy Surgery in ChildrenEPILEPSIA, Issue 7 2003Gregory P. Lee Summary: Purpose: Wada memory asymmetries were examined in children from four comprehensive epilepsy surgery centers who subsequently underwent epilepsy surgery to determine whether Wada memory performance could predict degree of seizure relief in children. Methods: One hundred fifty-six children (between ages 5 and 16 years) with intractable epilepsy underwent Wada testing before resective epilepsy surgery (93 within the left hemisphere, and 63 within the right hemisphere). Memory stimuli were presented soon after intracarotid amobarbital injection, and recognition memory for the items was assessed after return to neurologic baseline. Eighty-eight children underwent unilateral temporal lobe resection, and 68 had extratemporal lobe resections. One hundred four (67%) children were seizure free (Engel class I), and 52 (33%) were not seizure free (Engel classes II,IV) at follow-up (mean follow-up interval, 2.3 years). Results: Seizure-free children recalled 19.3% more Wada memory items after ipsilateral injection than did non,seizure-free children (p = 0.008). If analysis was restricted to youngsters with temporal lobectomies (TLs), seizure-free children recalled 27.7% more items after ipsilateral injection than did non,seizure-free TL children (p = 0.004). With regard to individual patient prediction, 75% of children who had memory score asymmetries consistent with the seizure focus were seizure free. In contrast, only 56% of children whose memory score asymmetries were inconsistent with the seizure focus were seizure free (p = 0.01). Conclusions: Results suggest that Wada memory performance asymmetries are related to the degree of seizure relief after epilepsy surgery in children and adolescents. [source] Involvement of the human thalamus in relational and non-relational memoryEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 12 2008Eleonore Soei Abstract Damage to the human thalamus has been associated with selective anterograde recognition memory impairments. Recently, recognition memory has been subdivided into relational and non-relational memory. The aim of the present study was to assess the potentially differential involvement of the human thalamus in relational and non-relational memory. Ten patients with focal ischemic thalamic lesions were compared to individualized control groups of healthy subjects matched to each individual patient on age and IQ. Six patients showed poorer relational memory than their respective control samples. None of the 10 patients showed a significant deficit on the non-relational memory task. These observations suggest an involvement of the thalamus in relational memory, and are discussed in terms of disruption of mediotemporal-thalamic and thalamic-fronto-striatal circuits. [source] Early life modulators and predictors of adult synaptic plasticityEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 2 2006Katherine G. Akers Abstract Early life experience can induce long-lasting changes in brain and behaviour that are opposite in direction, such as enhancement or impairment in regulation of stress response, structural and functional integrity of the hippocampus, and learning and memory. To explore how multiple early life events jointly determine developmental outcome, we investigated the combined effects of neonatal trauma (anoxia on postnatal day 1, P1) and neonatal novelty exposure (P2,21) on adult social recognition memory (3 months of age) and synaptic plasticity in the CA1 of the rat hippocampus (4.5,8 months of age). While neonatal anoxia selectively reduced post-tetanic potentiation (PTP), neonatal novel exposure selectively increased long-term potentiation (LTP). No interaction between anoxia and novelty exposure was found on either PTP or LTP. These findings suggest that the two contrasting neonatal events have selective and distinct effects on two different forms of synaptic plasticity. At the level of behaviour, the effect of novelty exposure on LTP was associated with increased social memory, and the effect of anoxia on PTP was not accompanied by changes in social memory. Such a finding suggests a bias toward the involvement of LTP over PTP in social memory. Finally, we report a surprising finding that an early behavioural measure of emotional response to a novel environment obtained at 25 days of age can predict adult LTP measured several months later. Therefore, individual differences in emotional responses present during the juvenile stage may contribute to adult individual differences in cellular mechanisms that underlie learning and memory. [source] Perirhinal cortex neuronal activity related to long-term familiarity memory in the macaqueEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 7 2003Christian Hölscher Abstract Lesion studies suggest that the perirhinal cortex plays a role in object recognition memory. To analyse its role, the activity of single neurons in the perirhinal cortex was recorded in three rhesus monkeys (Macaca mulatta) performing a delayed matching-to-sample task with up to three intervening stimuli. A set of familiar visual stimuli was used. Some neurons had activity related to working memory, in that they responded more to the sample than to the match image within a trial, as shown previously. However, when a novel set of stimuli was introduced, the neuronal responses were on average only 47% of the magnitude of the responses to the familiar set of stimuli. Moreover, it was shown in eight different replications in three monkeys that the responses of the perirhinal cortex neurons gradually increased over hundreds of presentations of the new set of (initially novel) stimuli to become as large as with the already familiar stimuli. The mean number of 1.3-s presentations to induce this effect was 400 occurring over 7,13 days. These results show that perirhinal cortex neurons represent the very long-term familiarity of visual stimuli. A representation of the long-term familiarity of visual stimuli may be important for many aspects of social behaviour, and part of the impairment in temporal lobe amnesia may be related to the difficulty of building representations of the degree of familiarity of stimuli. [source] PKM, maintains 1-day- and 6-day-old long-term object location but not object identity memory in dorsal hippocampusHIPPOCAMPUS, Issue 6 2010Oliver Hardt Abstract Continuous activity of the atypical protein kinase C isoform M zeta (PKM,) is necessary for maintaining long-term memory acquired in aversively or appetitively motivated associative learning tasks, such as active avoidance, aversive taste conditioning, auditory and contextual fear conditioning, radial arm maze, and watermaze. Whether unreinforced, nonassociative memory will also require PKM, for long-term maintenance is not known. Using recognition memory for object location and object identity, we found that inactivating PKM, in dorsal hippocampus abolishes 1-day and 6-day-old long-term recognition memory for object location, while recognition memory for object identity was not affected by this treatment. Memory for object location persisted for no more than 35 days after training. These results suggest that the dorsal hippocampus mediates long-term memory for where, but not what things have been encountered, and that PKM, maintains this type of spatial knowledge as long as the memory exists. © 2009 Wiley-Liss, Inc. [source] From learning to forgetting: Behavioral, circuitry, and molecular properties define the different functional states of the recognition memory traceHIPPOCAMPUS, Issue 5 2010Rocío Romero-Granados Abstract Neuropsychological analyses of amnesic patients, as well as lesion experiments, indicate that the temporal lobe is essential for the encoding, storage, and expression of object recognition memory (ORM). However, temporal lobe structures directly involved in the consolidation and reconsolidation of these memories are not yet well-defined. We report here that systemic administration of a protein synthesis inhibitor before or up to 4 h after training or reactivation sessions impairs consolidation and reconsolidation of ORM, without affecting short-term memory. We have also observed that ORM reconsolidation is sensitive to protein synthesis inhibition, independently of the ORM trace age. Using bdnf and egr-1 gene expression analysis, we defined temporal lobe areas related to consolidation and reconsolidation of ORM. Training and reactivation 21 days after ORM acquisition sessions provoked changes in bdnf mRNA in somatosensory, perirhinal, and hippocampal cortices. Reactivation 2 days after the training session elicited changes in bdnf and egr-1 mRNA in entorhinal and prefrontal cortices, while reactivation 9 days post-training provoked an increase in egr-1 transcription in somatosensory and entorhinal cortices. The differences in activated circuits and in the capacity to recall the memory trace after 9 or 21 days post-training suggest that memory trace suffers functional changes in this period of time. All these results indicate that the functional state of the recognition memory trace, from acquisition to forgetting, can be specifically defined by behavioral, circuitry, and molecular properties. © 2009 Wiley-Liss, Inc. [source] Ventral hippocampal involvement in temporal order, but not recognition, memory for spatial informationHIPPOCAMPUS, Issue 3 2008John G. Howland Abstract The hippocampus is critical for spatial memory. Recently, subregional differences in the function of hippocampus have been described in a number of behavioral tasks. The present experiments assessed the effects of reversibly lesioning either the dorsal (dHip) or ventral hippocampus (vHip) on spontaneous tests of spatial recognition and temporal order memory. We report that although the dHip is necessary for spatial recognition memory (RM) (distinguishing a novel from a familiar spatial location), the vHip is involved in temporal order memory (the capacity to distinguish between two spatial locations visited at different points in time), but not RM. These findings and others are consistent with the hypothesis that temporal order memory is supported by an integrated circuit of limbic areas including the vHip and the medial prefrontal cortex. © 2007 Wiley-Liss, Inc. [source] Effects of hippocampal lesions on the monkey's ability to learn large sets of object-place associations,HIPPOCAMPUS, Issue 4 2006Annabelle M. Belcher Abstract Earlier studies found that recognition memory for object-place associations was impaired in patients with relatively selective hippocampal damage (Vargha-Khadem et al., Science 1997; 277:376,380), but was unaffected after selective hippocampal lesions in monkeys (Malkova and Mishkin, J Neurosci 2003; 23:1956,1965). A potentially important methodological difference between the two studies is that the patients were required to remember a set of 20 object-place associations for several minutes, whereas the monkeys had to remember only two such associations at a time, and only for a few seconds. To approximate more closely the task given to the patients, we trained monkeys on several successive sets of 10 object-place pairs each, with each set requiring learning across days. Despite the increased associative memory demands, monkeys given hippocampal lesions were unimpaired relative to their unoperated controls, suggesting that differences other than set size and memory duration underlie the different outcomes in the human and animal studies. © 2005 Wiley-Liss, Inc. [source] Word imageability affects the hippocampus in recognition memoryHIPPOCAMPUS, Issue 6 2005Peter Klaver Abstract Concrete words, whose meanings are readily imagined, are better remembered than abstract words. However, the neural correlates of this effect are poorly understood. Here, we investigated the effect of imageability on brain activity in the medial temporal lobe (MTL) processes underlying recognition memory. We recorded event-related potentials (ERPs) via depth electrodes from within the MTL in 14 patients with drug-resistant epilepsy. Patients performed a continuous word recognition task with words of high and low imageability (controlled for word frequency). Behaviorally, recognition performance was better for high, compared to low, imageable words. Two ERP components associated with recognition memory, the AMTL-N400 and the hippocampal late negative component, showed an old/new effect, but only the hippocampal P600 showed a main effect of imageability. We suggest that the hippocampal effect of imageability in recognition memory may be associated with conceptual or pictorial information processing of concrete words. © 2005 Wiley-Liss, Inc. [source] Lag-sensitive repetition suppression effects in the anterior parahippocampal gyrusHIPPOCAMPUS, Issue 5 2005Craig J. Brozinsky Abstract Single-unit recording studies of monkeys have shown that neurons in perirhinal and entorhinal cortex exhibit activity reductions following stimulus repetition, and some have suggested that these "repetition suppression" effects may represent neural signals that support recognition memory. Critically, repetition suppression effects are most pronounced at short intervals between stimulus repetitions. Here, we used event-related functional magnetic resonance imaging (fMRI) to identify repetition suppression effects in the human medial temporal lobe and determine whether these effects are sensitive to the length of the interval between repetitions. Twenty-one participants were scanned while performing a continuous recognition memory task in which the interval between item repetitions was parametrically varied from 2 to 32 intervening items. We found evidence of repetition suppression in the anterior parahippocampal gyrus, but only when the repetition interval was relatively short. Moreover, bilateral hippocampal regions showed lag-sensitive repetition effects. Our results demonstrate that activity in the human medial temporal cortex, like that of monkeys, exhibits repetition suppression effects that are sensitive to the length of the interval between repetitions. © 2005 Wiley-Liss, Inc. [source] Rats with lesions of the hippocampus are impaired on the delayed nonmatching-to-sample task,HIPPOCAMPUS, Issue 2 2001Robert E. Clark Abstract Rats with ibotenic acid lesions of the hippocampus (H-IBO) were trained on the trial-unique delayed nonmatching-to-sample task (DNMS) using a short delay of 4 s. The H-IBO group learned the nonmatching rule as quickly as control animals. However, performance was impaired on the DNMS task when the delay between the sample and choice phase was increased to 1 or 2 min. The use of 4-s delay (probe) trials indicated that the H-IBO animals retained the nonmatching-to-sample rule throughout testing. In a second experiment, using the same groups of rats, extended training at the 1-min delay did not ameliorate the deficit produced by H-IBO lesions. The finding of impaired recognition memory in rats after hippocampal lesions is consistent with findings from humans and monkeys. Several methodological issues are considered that have complicated the interpretation of earlier studies of recognition memory in rats following hippocampal lesions. The capacity for recognition memory in humans, monkeys, and rodents is discussed as a straightforward example of hippocampus-dependent (declarative) memory. Hippocampus 2001;11:176,186. © 2001 Wiley-Liss, Inc. [source] SSRIs and cognitive performance in a working sampleHUMAN PSYCHOPHARMACOLOGY: CLINICAL AND EXPERIMENTAL, Issue 8 2005Emma J. K. Wadsworth Abstract Background Studies of the impact of antidepressant use on cognitive performance have frequently been carried out among the elderly or on healthy volunteers. Comparatively little research has considered their impact on a relatively young, working population, particularly within the context of everyday life. Aims To examine any association between SSRI use and cognitive performance, mood and human error at work. Methods SSRI users and controls completed a battery of laboratory based computer tasks measuring mood and cognitive function pre- and post-work at the start and end of a working week. They also completed daily diaries reporting their work performance. Results SSRI use was associated with memory impairment: specifically poorer episodic, though not working or semantic memory. Effects of SSRI use on recognition memory seemed to vary according to the underlying psychopathology, while effects on delayed recall were most pronounced among those whose symptoms had not (yet) resolved. There were no detrimental effects on psychomotor speed, attention, mood or perceived human error at work. Conclusions The findings lend support to the SSRIs comparative safety, even among workers, particularly as the symptoms of the underlying psychopathology are successfully addressed. Possible memory impairments may, however, be found in those taking SSRIs. Copyright © 2005 John Wiley & Sons, Ltd. [source] Electrophysiological Signals of Familiarity and Recency in the Infant BrainINFANCY, Issue 5 2010Kelly A. Snyder Electrophysiological work in nonhuman primates has established the existence of multiple types of signals in the temporal lobe that contribute to recognition memory, including information regarding a stimulus's relative novelty, familiarity, and recency of occurrence. We used high-density event-related potentials (ERPs) to examine whether young infants represent these distinct types of information about previously experienced items. Twenty-four different highly familiar and initially novel items were each repeated exactly once either immediately (Experiment 1), or following one intervening item (Experiment 2). A late slow wave (LSW) component of the ERP exhibited neural responses consistent with recency signals over right-central leads, but only when there were no intervening stimuli between repetitions. The LSW also exhibited responses consistent with familiarity signals over anterior-temporal leads, but only when there were intervening stimuli between repetitions. A mid-latency negative component (i.e., the Nc) also distinguished familiar from novel items, but did not exhibit a pattern of responding consistent with familiarity signals. These findings suggest that infants encode information about a variety of objects from their natural environments into long-term memory, and can discriminate between familiar and unfamiliar items, and between recently seen and new items, very quickly (within 1 sec). They also suggest that infants represent information about not only whether a stimulus is familiar or unfamiliar but also whether it has been seen recently. [source] Individual Differences in Infants' Recognition of Briefly Presented Visual StimuliINFANCY, Issue 3 2001Janet E. Frick Infants' recognition memory has been shown to be related to individual differences in look duration and level of heart period variability. This study examined the effect of individual differences in these 2 measures on infants' recognition of briefly presented visual stimuli using a paired-comparison recognition-memory paradigm. A sample of 35 full-term infants was studied longitudinally at 14, 20, and 26 weeks of age. Recognition memory for briefly presented stimuli was tested in 6 experimental conditions, with delays corresponding to different heart-rate-defined phases of attention. The 20-and 26-week-old infants, and infants with high levels of heart period variability, generally showed more evidence of recognition memory for briefly presented visual stimuli. Greater evidence of recognition memory was observed when stimuli were presented during sustained attention. Infants with more mature baseline physiological responses show greater evidence of recognition memory, and stimulus and procedural factors may be more important for the study of individual differences in infant visual attention than has previously been suggested. [source] Exploring the relation between memory, gestural communication, and the emergence of language in infancy: a longitudinal studyINFANT AND CHILD DEVELOPMENT, Issue 3 2006Mikael Heimann Abstract The relationship between recall memory, visual recognition memory, social communication, and the emergence of language skills was measured in a longitudinal study. Thirty typically developing Swedish children were tested at 6, 9 and 14 months. The result showed that, in combination, visual recognition memory at 6 months, deferred imitation at 9 months and turn-taking skills at 14 months could explain 41% of the variance in the infants' production of communicative gestures as measured by a Swedish variant of the MacArthur Communicative Development Inventories (CDI). In this statistical model, deferred imitation stood out as the strongest predictor. Copyright © 2006 John Wiley & Sons, Ltd. [source] Topographical recognition memory sensitive to amnestic mild cognitive impairment but not to depressionINTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 10 2006Emilie Ritter Abstract Objective Amnestic mild cognitive impairment (aMCI) involves episodic memory. The person who presents aMCI has a high risk of developing Alzheimer's disease (AD). However, prediction of deterioration to dementia in cases of aMCI can be confounded with depression due to lack of specificity on selective memory tests. Finding a test sensitive to aMCI but not to depression would be potentially most useful to subsequent longitudinal studies researching the neuropsychological markers of preclinical AD. We hypothesized that the performance on a topographical memory task would be sensitive to the aMCI condition, while depression would not influence such a performance. Participants and Methods A group of 137 community-dwelling French-speaking subjects between 55 and 70 years old was administered a topographical recognition memory task. Based on aMCI and depression criteria, 45 subjects were selected and divided into four groups: 11 patients with aMCI without depression, nine depressive patients with aMCI, ten depressive patients without cognitive impairment and 15 control subjects. The remaining non-selected participants did not belong to any of the previous interest groups. Results The ,aMCI' factor had a significant effect on the topographical recognition memory task scores, while the ,depression' factor did not. The aMCI patients performed worse than the non-aMCI. Conclusion Although these results were found with relatively small groups, deficits in topographical recognition memory were observed in aMCI patients and did not seem to be sensitive to depression. Further longitudinal studies are needed to examine whether deficits in topographical recognition memory are a neuropsychological marker of preclinical AD. Copyright © 2006 John Wiley & Sons, Ltd. [source] Differential age-related change of prose memory in older Hong Kong Chinese of higher and lower educationINTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 3 2004T. M. C. Lee Abstract Background Memory difficulty is one of the most common complaints of older people, with or without psychiatric conditions. It is therefore of utmost important to understand how normal ageing process impacts upon prose memory so as to gain insight into ways to differentiate pathological vs normal age-related changes of the recall of prose observed among older people. Objectives To understand the differential age-related change of prose memory in older Hong Kong Chinese of higher and lower education. Method Forty-eight normal, healthy Cantonese-speaking Chinese were recruited. Seventeen of them were younger, highly educated participants. Among the 31 older people recruited, 19 of them received education comparable with the younger participants and 12 were older people of low education. A prose passage was constructed to measure the different processes of prose memory, including learning efficiency, rate of forgetting, recall accuracy, accuracy of temporal sequence of information recalled, distortions, and recognition memory. Results As expected, ageing affected all the processes of prose memory measured, except the rate of forgetting. Apart from learning efficiency and rate of forgetting, education was observed to modify the effect of ageing on all the processes studied. Conclusions Changes of prose memory associated with ageing and the differential effect of education on prose recall among older people were discussed. The findings seem to suggest that prose memory is a multifaceted construct. Copyright © 2004 John Wiley & Sons, Ltd. [source] Social Presence and Children: Praise, Intrinsic Motivation, and Learning With ComputersJOURNAL OF COMMUNICATION, Issue 1 2004Cheryl Campanella Bracken The computers are social actors (CASA) paradigm asserts that human computer users interact socially with computers, and the paradigm has provided extensive evidence that this is the case for adults. This experiment examined whether or not children have similar reactions to computers by comparing children's predictable responses to praise from a teacher to their responses to praise from a computer. Eight- to 10-year-old participants (N= 42) received either praise or neutral feedback from a computer. Independent variables were the feedback (praise or neutral), and participants' age and gender. Dependent variables measured via a paper-and-pencil questionnaire were learning (recall and recognition memory), perceived ability, and intrinsic motivation. Results provide evidence that children do have social responses to computers and that such social responses can lead to increases in learning (recall and recognition) in young children. [source] Reference-independent ERP old/new effects of auditory and visual word recognition memory: Joint extraction of stimulus- and response-locked neuronal generator patternsPSYCHOPHYSIOLOGY, Issue 6 2007Jürgen Kayser Abstract To clarify polarity, topography, and time course of recognition memory ERP old/new effects during matched visual and auditory continuous word recognition tasks, unrestricted temporal PCA jointly analyzed stimulus- and response-locked, reference-free current source densities (31-channel, N=40). Randomization tests provided unbiased statistics for complete factor topographies. Old/new left parietal source effects were complemented by lateral frontocentral sink effects in both modalities, overlapping modality-specific P3 sources 160 ms preresponse. A mid-frontal sink 45 ms postresponse terminated the frontoparietal generator pattern, showed old/new effects consistent with bilateral activation of anterior cingulate and SMA, and preceded similar activity extending posteriorly along the longitudinal fissure. These methods separated old/new stimulus source (preresponse) and response sink (postresponse) effects from motor and modality-specific ERPs. [source] Visual novel stimuli in an ERP novelty oddball paradigm: Effects of familiarity on repetition and recognition memoryPSYCHOPHYSIOLOGY, Issue 1 2007Yael M. Cycowicz Abstract The orienting response, the brain's reaction to novel and/or out of context familiar events, is reflected by the novelty P3 of the ERP. Contextually novel events also engender high rates of recognition memory. We examined, under incidental and intentional conditions, the effects of visual symbol familiarity on the novelty P3 recorded during an oddball task and on the parietal episodic memory (EM) effect, an index of recollection. Repetition of familiar, but not unfamiliar, symbols elicited a reduction in the novelty P3. Better recognition performance for the familiar symbols was associated with a robust parietal EM effect, which was absent for the unfamiliar symbols in the incidental task. These data demonstrate that processing of novel events depends on expectation and whether stimuli have preexisting representations in long-term semantic memory. [source] Interfacing mind and brain: A neurocognitive model of recognition memoryPSYCHOPHYSIOLOGY, Issue 5 2000Axel Mecklinger A variety of processes contribute to successful recognition memory, some of which can be associated with spatiotemporally distinct event-related potential old/new effects. An early frontal and a subsequent parietal old/new effect are correlated with the familiarity and recollection subcomponents of recognition memory, respectively, whereas a late, postretrieval old/new effect seems to reflect an ensemble of evaluation processes that are set by the task context in which retrieval occurs. Both the early frontal and the parietal old/new effects are differentially modulated by the informational content (e.g., object forms and spatial locations) of recognition and seem to rely on brain systems damaged in amnesia. The late frontal effect appears to reflect prefrontal cortex activation. A neurophysiologically based model of recognition memory retrieval is presented and it is shown that coupling recognition memory subprocesses with distinct old/new effects allow examination of the time course of the processes that contribute to correct and to illusory memories. In conjunction with event-related functional magnetic resonance imaging activation patterns the brain systems recruited by various aspects of episodic memory retrieval can be identified. [source] Short duration power changes in the EEG during recognition memory for words and facesPSYCHOPHYSIOLOGY, Issue 5 2000A.P. Burgess Although memory has been widely studied using event-related potentials, memory-related changes in the electroencephalogram (EEG) have been relatively neglected. The aim of this study was to determine whether evidence could be found for memory-related changes in the EEG. EEG was recorded from a sample of healthy volunteers while they performed word and face recognition memory tasks. Data were analyzed using the method of event-related desynchronization. In the theta frequency range there was a short-duration increase in power that occurred in the first 250 ms that was maximal at temporal sites (T5/T6). For words, but not faces, there was a repetition effect in theta such that new words elicited greater synchronization than old words at the midline frontal electrode (Fz). In the alpha frequency range there was a lateralized repetition effect, which occurred from 750 ms. In upper alpha this effect was lateralized in the expected way with greater desynchronization at temporo-parietal sites on the left for words and on the right for faces. For lower alpha, the lateralization was reversed. The meanings of these findings are interpreted in the light of existing models of recognition memory. [source] Anxiety and terrorism: Automatic stereotypes affect visual attention and recognition memory for White and Middle Eastern facesAPPLIED COGNITIVE PSYCHOLOGY, Issue 3 2009Ruth Horry Automatic stereotypes and emotional state can affect cognitive processes such as attention, perception, and memory. Two experiments were carried out to investigate whether anxiety and stereotypes of Middle Easterners influence attention and recognition memory in White participants. A dot-probe procedure was used, with White and Middle Eastern faces as stimuli. The results showed that anxious participants who were exposed to terrorism-related words showed a visual bias toward Middle Eastern faces, and were more accurate at recognizing both White and Middle Eastern faces. Non-anxious participants, after exposure to the same primes, showed an attentional bias toward the White faces. Overall, participants were more accurate at recognizing the White faces than the Middle Eastern faces. Copyright © 2008 John Wiley & Sons, Ltd. [source] Brief exposure to a 50 Hz, 100 ,T magnetic field: Effects on reaction time, accuracy, and recognition memoryBIOELECTROMAGNETICS, Issue 3 2002John Podd Abstract The present study investigated both the direct and delayed effects of a 50 Hz, 100 ,T magnetic field on human performance. Eighty subjects completed a visual duration discrimination task, half being exposed to the field and the other half sham exposed. The delayed effects of this field were also examined in a recognition memory task that followed immediately upon completion of the discrimination task, Unlike our earlier studies, we were unable to find any effects of the field on reaction time and accuracy in the visual discrimination task. However, the field had a delayed effect on memory, producing a decrement in recognition accuracy. We conclude that after many years of experimentation, finding a set of magnetic field parameters and human performance measures that reliably yield magnetic field effects is proving elusive. Yet the large number of significant findings suggests that further research is warranted. Bioelectromagnetics 23:189,195, 2002. © 2002 Wiley-Liss, Inc. [source] The common adolescent bipolar phenotype shows positive biases in emotional processingBIPOLAR DISORDERS, Issue 6 2010Philippa L Rock Rock PL, Goodwin GM, Harmer CJ. The common adolescent bipolar phenotype shows positive biases in emotional processing. Bipolar Disord 2010: 12: 606,615. © 2010 The Authors. Journal compilation © 2010 John Wiley & Sons A/S. Objectives:, Bipolar disorder is associated with abnormalities in emotional processing that persist into periods of remission. However, studies of euthymic bipolar disorder patients may be confounded by the experience of mood episodes and medication. We therefore assessed an adolescent group for vulnerability markers associated with the bipolar phenotype. Methods:, The Mood Disorder Questionnaire (MDQ) is a screening tool for bipolar disorder that targets mood-elevation symptoms. We selected 32 high-scoring students (, 7 symptoms) with the adolescent bipolar phenotype and 30 low-scoring controls (, 3 symptoms) and screened them with the Mini International Neuropsychiatric Interview,Plus for bipolar disorder and other psychiatric disorders. We investigated emotional processing by assessing facial expression recognition, emotional memory, emotion-potentiated startle, and a dot-probe task. Results:, Of the high-MDQ participants, 12 were in remission from bipolar disorder defined by DSM-IV-TR and interview (bipolar II disorder/bipolar disorder not otherwise specified) and 3 from major depressive disorder. High-MDQ participants had higher levels of neuroticism, low mood, and lifetime anxiety comorbidity and alcohol dependence compared with low-MDQ participants. The high-MDQ group showed facilitated recognition of surprised and neutral facial expressions and enhanced processing of positive versus negative information in emotional recognition memory and emotion-potentiated startle. There were no effects on emotional categorisation/recall memory or attentional bias in the dot-probe task. Conclusions:, These results suggest that students with the common adolescent bipolar phenotype show positive emotional processing biases despite increased levels of neuroticism, low mood, and anxiety. Such effects may represent a psychological vulnerability marker associated with the bipolar phenotype. [source] | |||||||||||||||||||