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Selected AbstractsWomen's Sports Media, Self-Objectification, and Mental Health in Black and White Adolescent FemalesJOURNAL OF COMMUNICATION, Issue 2 2003Kristen Harrison Recent surveys have suggested that sports media exposure may be linked to adolescents' body perceptions. This study tested this relationship from the perspective of objectification theory (Fredrickson & Roberts, 1997) by surveying and experimenting with 426 adolescent females aged 10,19. Sports magazine reading predicted greater body satisfaction among older adolescents, regardless of whether they participated in sports. Self-objectification in adolescents of all ages predicted mental health risks including body shame, disordered eating, and depression. Participants also viewed a video depicting men's sports, women's lean sports, or women's nonlean sports. For White participants, watching lean sports increased self-objectification, whereas for participants of color, watching nonlean sports had the same effect. Discussion focuses on self-objectification in adolescents and how cultural differences in the female body ideal are reflected in portrayals of female athletes. [source] Modeling distributions of disjunct populations of the Sierra Madre SparrowJOURNAL OF FIELD ORNITHOLOGY, Issue 3 2008Octavio R. Rojas-Soto ABSTRACT Sierra Madre Sparrows (Xenospiza baileyi) are among the least known of all bird species in Mexico. Recent surveys have discovered previously unknown populations and the current known distribution of Sierra Madre Sparrows consists of two populations separated by >800 km. We used available distributional information to develop ecological niche models that (1) predict much of the distribution potential of the species, (2) establish that the broad disjunction separating the two populations has ecological correlates that appear to be important to the distributional of these sparrows, and (3) illustrate the extremely restricted ecological distribution of the species. We used two sets of climatic and topographic variables, with one including all 22 variables available and the second with only six variables that were positively related to quality of distributional models. Although indications of differences between the two sets of populations were found based on the full 22-dimensional environmental dataset, such a highly dimensional analysis is vulnerable to over-fitting; models based on the reduced dataset indicated that the two populations occur in areas with similar ecological conditions. Our models also suggest that southern population of Sierra Madre Sparrows covers most of their potential range in that region. The potential range of the northern population, however, extends beyond known points of occurrence. To clarify the distribution of Sierra Madre Sparrows and evaluate their status and conservation opportunities, detailed searches for additional populations in areas identified by the model are needed. SINOPSIS El gorrión serrano (Xenospiza baileyi) se encuentra entre las especies menos conocidas de México. En un estudio reciente se descubrieron nuevas poblaciones, por lo que la distribución actual de esta ave está conformada por dos meta-poblaciones separadas por más de 800 km. Utilizamos la información disponible sobre su distribución para desarrollar modelos del nicho ecológico que: 1) predigan la mayor parte de la distribución potencial de la especie, 2) establezcan que la amplia separación de las dos poblaciones está correlacionada con condiciones ecológicas que parecen ser importantes para la distribución de la especie y 3) ilustren la extrema restricción ecológica que caracteriza la distribución de la especie. Para generar los modelos, utilizamos dos conjuntos de variables climatológicas y topográficas. Uno con 22 variables y el otro con las seis variables que estaban positivamente correlacionadas con la calidad de los modelos de distribución. Aunque se encontraron indicios de diferencias ecológicas entre las dos poblaciones con base en las 22 variables ambientales estudiadas, el análisis con tantas dimensiones es sensible a un efecto de sobre-ajuste. Los modelos producidos con el subconjunto de seis variables indicaron que las dos poblaciones se encuentran en áreas con condiciones ecológicas similares. Nuestros modelos sugieres que la población del sur ocupa la mayor parte de su área de distribución potencial en la región. No obstante, la distribución potencial de la población del norte es mucho más amplia que su distribución conocida. Es necesario realizar búsquedas minuciosas del gorrión serrano en los sitios identificados por el modelo propuesto para definir adecuadamente su distribución, evaluar su estatus y buscar oportunidades para su conservación. [source] Chronic prostatitis and chronic pelvic pain in men: aetiology, diagnosis and management,JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY & VENEREOLOGY, Issue 3 2002GA Luzzi ABSTRACT Patients with chronic prostatitis/pelvic pain syndrome typically report genital or pelvic pain (in or around the penis, perineum, scrotum) lasting >3 months. Whereas true chronic bacterial prostatitis is an uncommon condition characterised by recurrent prostatic and urinary infection, chronic pelvic pain syndrome (CPPS) is a common condition in which no infection is found. Recent surveys suggest a prevalence of 2.5,3% for CPPS. The four-glass test, traditionally used to distinguish inflammatory and inflammatory forms of CPPS, has not been adequately validated; whether the distinction is clinically meaningful is increasingly questioned. The aetiology of CPPS is not known; urodynamic studies imply a neuromuscular origin. More recent work supports a role for proinflammatory cytokines in the pathogenesis. In the management of chronic bacterial prostatitis, trials support the use of quinolone antibiotics as first-line treatment. In contrast, the management of CPPS is generally unsatisfactory, as no reliable treatment has been identified. Treatments commonly tried include antibiotics (notably tetracyclines, quinolones and macrolides), anti-inflammatory agents, and alpha blockers. Newer approaches include trials of finasteride, quercetin and rofecoxib. A recent systematic review demonstrated that none of the current diagnostic and treatment methods for CPPS is supported by a robust evidence base. [source] Does hybridization between divergent progenitors drive whole-genome duplication?MOLECULAR ECOLOGY, Issue 16 2009RICHARD J. A. BUGGS Abstract Hybridization and whole-genome duplication are both potential mechanisms of rapid speciation which sometimes act in concert. Recent surveys, showing that homoploid hybrid species tend to be derived from parents that are less evolutionarily divergent than parents of polyploid hybrid species (allopolyploids), have been interpreted as supporting a hypothesis that high divergence between hybridizing species drives whole-genome duplication. Here, we argue that such conclusions stem from problems in sampling (especially the omission of autopolyploids) and null model selection, and underestimate the importance of selection. The data simply demonstrate that hybridization between divergent parents has a higher probability of successfully producing a species if followed by polyploidization. [source] Stellar contributors to the hard X-ray background?MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 3 2000Priyamvada Natarajan We use simple energetic arguments to estimate the contribution of massive X-ray binaries and supernova remnants to the cosmic X-ray background (XRB) at energies in excess of 2 keV. Recent surveys have shown that active galactic nuclei (AGN) probably account for most of the hard XRB (E>2 keV), but there have been many suggestions that star-forming galaxies could emerge at fainter fluxes and perhaps account for a significant fraction of the soft and hard X-ray energy density. Assuming that the formation rate of massive X-ray binaries (MXRBs) traces the global star-formation rate, we find that their integrated contribution to the hard XRB can be estimated and is shown to be small (at less than the 1 per cent level). Similarly, the integrated flux of supernovae (SN) is also shown to be insignificant, or at most comparable to MXRBs. AGN therefore remain the most viable candidates for producing the hard XRB, unless additional processes can be shown to dominate the global hard X-ray emission in distant starburst galaxies. [source] A pilot respiratory health assessment of nail technicians: Symptoms, lung function, and airway inflammation ,,AMERICAN JOURNAL OF INDUSTRIAL MEDICINE, Issue 11 2009Susan R. Reutman PhD Abstract Background Recent surveys suggest nail technicians, particularly artificial nail applicators, have increased respiratory symptoms and asthma risk. Methods We examined lung function (n,=,62) and a marker of airway inflammation, i.e., exhaled nitric oxide (ENO) (n,=,43), in a subset of nail technician and control participants in a pilot health assessment. Results Bivariate analysis of technicians demonstrated that job latency was inversely correlated with FEV1 percent predicted (FEV1PP) (r,=,,0.34, P,=,0.03) and FVCPP (r,=,,0.32, P,=,0.05). Acrylic gel contact hours were inversely correlated with FEV1PP (r,=,,0.38, P,=,0.02) and FVCPP (r,=,,0.47, P,=,0.003). Current smoking was inversely and significantly (P,,,0.05) associated with ENO in bivariate analysis. Log 10 ENO levels were directly correlated with job latency (P,=,0.012) and gel nail application (P,=,0.026) in multivariable analyses. Conclusions These positive pilot respiratory test results warrant additional future investigation. Am. J. Ind. Med. 52:868,875, 2009. © 2009 Wiley-Liss, Inc. [source] Managing alliance relationships: Key challenges in the early stages of collaborationR & D MANAGEMENT, Issue 1 2002Mícheál J. Kelly Recent surveys indicate that executives of technology companies consider strategic alliances to be central to their competitive strategies. Yet the barriers to successful alliances are formidable. In many instances, these barriers develop in the early stages of an alliance. This study identifies and analyzes the types of challenges that companies face in the start,up phase of their alliances. It is based on a survey and interviews with executives in the Canadian high technology industry. The study finds that the principal challenges in the first year of an alliance relate to relationship issues between the partners. It suggests stronger attention to these issues in the design and implementation of an alliance. The paper concludes with guidelines to build and sustain effective working relationships between partners. [source] FS13.3 Development of risk reduction strategies for preventing dermatitisCONTACT DERMATITIS, Issue 3 2004Terry Brown Introduction:, A recent survey of the UK printing industry found a prevalence of 11% of occupational contact dermatitis (OCD), much higher than previously identified. Objective:, This pilot study aimed to evaluate risk reduction strategies derived from recommendations of a literature review of preventive intervention studies and a series of focus groups of printers and observations of printers undertaking their normal duties. Methods:, Four interventions were evaluated: (1) Provision of gloves of the correct size/type, plus use of an after-work skin cream; (2) Provision of information; (3) Provision of skin checks; (4) Development of best practice skin care policy. Each intervention was evaluated in two companies over a three-month period, at the end of which printers and managers were interviewed as to the effectiveness and acceptability of each intervention. Results:, Although this pilot study was short, all interventions were acceptable to some extent. The prevalence of frank dermatitis fell over the study period, particularly in intervention (3). Intervention (1) achieved an improvement of awareness in both management and workforce and an increase in the use of both gloves and cream. Intervention (2) highlighted problems of dissemination and the need for relevant information in an appropriate format. However. no single intervention was completely effective. Conclusions:, This qualitative research approach forms an essential first stage to improving understanding of ways in which OCD may be reduced among workers in the printing industry, and points towards the need for further testing of preventive strategies in larger-scale intervention trials, in printing and other industries. [source] Using environmental management systems to increase firms' competitivenessCORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT, Issue 2 2003Dr Gerusa Giménez Leal The traditional view that has predominated in the industrial world has been that of a total clash between economic activity and the protection of the environment. This perception has evolved somewhat and currently environmental considerations have become a fundamental part of business practices. The first step that may help organizations to face these new challenges lies in recognizing the competitive advantages that environmental management systems, EMSs, can bring. This article presents the findings of a recent survey of Spanish firms. The results suggest that a positive relationship exists between the effects of EMSs and improving firms' competitiveness. Copyright © 2003 John Wiley & Sons, Ltd. and ERP Environment [source] MENTORS AND CRIMINAL ACHIEVEMENT,CRIMINOLOGY, Issue 1 2006CARLO MORSELLI Much of the research focusing on conventional occupations concludes that mentored individuals are more successful in their careers than those who are not mentored. Early research in criminology made a similar claim. Yet contemporary criminology has all but ignored mentors. We investigate this oversight, drawing on Sutherland's insights on tutelage and criminal maturation and incorporating ideas on human and social capital. We argue that mentors play a key role in their protégés' criminal achievements and examine this hypothesis with data from a recent survey of incarcerated adult male offenders in the Canadian province of Quebec. In this sample, a substantial proportion of respondents reported the presence of an influential individual in their lives who introduced them to a criminal milieu and whom they explicitly regarded as a mentor. After studying the attributes of offenders and their mentors, we develop a causal framework that positions criminal mentor presence within a pathway that leads to greater benefits and lower costs from crime. [source] ENDOSCOPIC SUBMUCOSAL DISSECTION IN THE UPPER GASTROINTESTINAL TRACT: PRESENT AND FUTURE VIEW OF EUROPEDIGESTIVE ENDOSCOPY, Issue 2009Horst Neuhaus In Western countries endoscopic mucosal resection (EMR) has been widely accepted for treatment of early Barrett`s neoplasia and flat or depressed colorectal adenomas. In contrast endoscopic submucosal dissection (ESD) is infrequently performed for several reasons. It seems to be difficult to overcome the learning curve of this difficult technique because of the low case volume of early gastric cancer. On the other hand ESD of esophageal or colorectal lesions is even more challenging and is considered to be inappropriate for learning. In addition the indication for esophageal or colorectal ESD is controversial in view of excellent results of the well established EMR technique which is less time-consuming and safer than ESD. A recent survey of leading Western endoscopy centers indicated the limited experience with ESD with a low number of cases for all potential indications. Only a few training courses have been established and the number of ongoing clinical studies is limited. Only 12 out of 340 published articles on "endoscopic mucosal dissection" were reported from Western countries. A better acceptance of ESD requires improvement of the technique to allow an easier, faster and safer approach. There is a strong demand for structured training courses and limitations of human cases to selected centers which participate in prospective trials. A close collaboration between Western and Asian centers is recommended for improvement of the ESD technique and its clinical application. [source] From Scientific Apprentice to Multi-skilled Knowledge Worker: changes in Ph.D education in the Nordic-Baltic AreaEUROPEAN JOURNAL OF EDUCATION, Issue 3 2007ANDREAS ÖNNERFORS There is no doubt that what is generally referred to as ,Ph.D education' has undergone dramatic changes in Europe in recent years. Whereas the Bologna Process, launched in 1999, originally had in mind to make it easier for undergraduate students to gain international experience and enhance their employability by facilitating mobility and transparency of higher education in Europe, the idea of a ,third cycle' of doctoral studies came relatively late in the discussion (2003). For some academic cultures, the idea of educating doctoral students was and still is perceived as a threat against academic freedom, originality and credibility. Other academic cultures have already long adopted Ph.D training schemes as an integrated part of training future scientists and knowledge workers. This article presents the result of a recent survey on Ph.D training in the Nordic-Baltic Area (Andreas Önnerfors: ,Ph.D-training/PGT in the Nordic-Baltic Area', Exploring the North: papers in Scandinavian Culture and Society 2006:1, Lund 2006) initiated by the Nordic research organisation NordForsk, which discusses new concepts of doctoral education and training in the five Nordic and the three Baltic countries as well as in Russia, Poland and three northern states of the Federal Republic of Germany. Whereas there is great correspondence in the performance of doctoral training and education in the Nordic countries and changes have been introduced permanently for about 30 years, Poland, Germany and Russia are battling with their academic traditions and the challenge of adapting their academic cultures to joint European standards. This concerns especially the phenomenon of two postgraduate degrees (the Ph.D and a further degree) and the view upon training elements in doctoral studies. After their independence, the three Baltic countries rapidly adapted their systems of higher education to the Nordic model. [source] Sirococcus shoot blight on Picea spinulosa in BhutanFOREST PATHOLOGY, Issue 1 2007T. Kirisits Summary During a recent survey of forest tree diseases in Western and Central Bhutan, Sirococcus shoot blight and an associated Sirococcus sp. were found on saplings and mature trees of Eastern Himalayan spruce (Picea spinulosa). Based on morphological characteristics and DNA sequence comparisons of the ITS region of the rDNA operon, representative isolates from Bhutan were unequivocally identified as Sirococcus conigenus. The DNA sequence data also showed that these isolates belong to the P group of S. conigenus. To our best knowledge, this is the first report of Sirococcus shoot blight from the Himalayas or any other part of Asia. Sirococcus conigenus does not appear to cause dramatic damage at the moment, but this fungus has the potential to cause severe disease problems on P. spinulosa in Bhutan. [source] Teamworking and organizational performance: A review of survey-based researchINTERNATIONAL JOURNAL OF MANAGEMENT REVIEWS, Issue 2 2008Anne Delarue This paper presents a review of recent survey-based research looking at the contribution of teamwork to organizational performance. In particular, it focuses on empirical studies in which both teamwork and performance are directly measured in a quantitative way. The paper begins by identifying four interrelated dimensions of teamwork effectiveness: attitudinal, behavioural, operational and financial. The first two represent transmission mechanisms by which organizational performance can be improved. The latter two provide direct measures of organizational outcomes. The review shows that teamworking has a positive impact on all four dimensions of performance. It also reveals that, when teamwork is combined with structural change, performance can be further enhanced. The paper concludes by highlighting some important research gaps that future studies could address. [source] Inconsistencies between reported test statistics and p- values in two psychiatry journalsINTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH, Issue 4 2007David Berle Abstract A recent survey of the British Medical Journal (BMJ) and Nature revealed that inconsistencies in reported statistics were common. We sought to replicate that survey in the psychiatry literature. We checked the consistency of reported t -test, F -test and ,2 -test values with their corresponding p -values in the 2005 issues of the Australian and New Zealand Journal of Psychiatry (ANZJP) and compared this with the issues of the ANZJP from 2000, and with a similar journal, Acta Psychiatrica Scandinavica (APS). A reported p -value was ,inconsistent' if it differed (at its reported number of decimal places) from our calculated p -values (using three different software packages), which we based on the reported test statistic and degrees of freedom. Of the 546 results that we checked, 78 (14.3%) of the p -values were inconsistent with the corresponding degrees of freedom and test statistic. Similar rates of inconsistency were found in APS and ANZJP, and when comparing the ANZJP between 2000 and 2005. The percentages of articles with at least one inconsistency were 8.5% for ANZJP 2005, 9.9% for ANZJP 2000 and 12.1% for APS. We conclude that inconsistencies in p -values are common and may reflect errors of analysis and rounding, typographic errors or typesetting errors. Suggestions for reducing the occurrence of such inconsistencies are provided. Copyright © 2008 John Wiley & Sons, Ltd. [source] The Archaeology of the Kelp Industry in the Northern Islands of IrelandINTERNATIONAL JOURNAL OF NAUTICAL ARCHAEOLOGY, Issue 2 2006W. Forsythe The manufacture of kelp in Ireland from the 17th to early 20th centuries provided soda and later iodine for contemporary industries. It was an immensely important element of coastal economies, and notably for island communities, often impoverished and with limited agricultural means. This paper traces the origins and development of the industry in Ireland and examines the evidence for production in the islands off the northern coast. The results of a recent survey of surviving kelp monuments are presented. The form of the monuments, in particular kilns, is considered as well as the role of the industry in island economies. © 2006 The Author [source] Work, health and welfare: new challenges,INTERNATIONAL JOURNAL OF SOCIAL WELFARE, Issue 2006Johannes SiegristArticle first published online: 19 JUN 200 Gainful employment is a core prerequisite of individual autonomy and the well-being of a majority of adult people, preventing them from economic dependence on welfare transfer. Yet, the quality of work and employment acts as an important determinant of work ability and health. This contribution offers an extended framework for analysing quality of work by introducing a theoretical approach towards assessing an adverse psychosocial work environment. Two models are briefly described, the demand-control and effort-reward imbalance models, and selected empirical evidence demonstrating their health-adverse effects is summarised. Importantly, poor quality of work in addition reinforces employees' intentions to leave their job as soon as possible. Results from a recent survey in ten European countries support this observation. In view of these findings and their relevance for occupational health and the prevention of early retirement, policy implications aimed at improving quality of work are discussed. [source] Building on formal education: employers' approaches to the training and development of new recruits in the People's Republic of ChinaINTERNATIONAL JOURNAL OF TRAINING AND DEVELOPMENT, Issue 3 2003Katharine Venter Conceptions of modern management and of skill in China have developed out of quantitative, production oriented traditions that have tended to downplay the human side of management, training and development. Based on recent survey and case study research this paper argues that some organisations are moving away from such narrow definitions. These tend to be resource rich, larger enterprises, often in modern growth sectors and organisations exposed to foreign practice (either by virtue of foreign ownership or investment, or as a result of exposure to the pressures of global competition through operation in international markets). Skills shortages are faced by organisations throughout China. However, employers do not generally feel that the education system is serving to address these skills needs. The varying conceptions of modern management shape the manner in which organisations recruit from, and build, on formal education provision. Many resource rich employers are using formal education as a selection mechanism, selecting the educational elite and continuing to develop them. Those organisations that have limited access to highly qualified recruits are also least likely to be in a position to provide extensive or high quality training. Consequently the divide between resource rich and resource poor organisations, in terms of both organisational resources and employees' opportunities for skill acquisition, learning and development, seems likely to widen. [source] Mumbai's Mysterious Middle ClassINTERNATIONAL JOURNAL OF URBAN AND REGIONAL RESEARCH, Issue 4 2006JAN NIJMAN Mumbai forms the décor to an interesting set of relationships among economic liberalization, globalization, class restructuring and an unprecedented housing construction boom. The much talked about new Indian middle class is primarily an urban phenomenon and seems nowhere more salient than in India's commercial capital and largest city. This article seeks to undo some of the mysteries that surround the new middle class: how it can be empirically defined, whether and how it is growing, how class restructuring in Mumbai conforms (or not) to Western arguments about social polarization, and how any such class restructuring can best be explained. The empirical analysis employs existing data from various sources on income and consumption in Mumbai (and India at large) and reports on selected findings from a recent survey by the author on housing, class and upward mobility among households in newly constructed homes in Greater Mumbai. Data on the distribution of household incomes show that the upper-middle income classes have grown relative to the total, that the lower-middle income classes have shrunk, and that the ranks of the poor have expanded slightly. Survey data among new home buyers in Mumbai suggest little upward mobility. Discourse about the ,new middle class' tends to focus on consumption rather than income and additional findings indicate that much of the growth in consumption is credit-based. [source] The Embedded Nature of Rural Legal Services: Sustaining Service Provision in WalesJOURNAL OF LAW AND SOCIETY, Issue 2 2007Alex Franklin There is a considerable amount of literature on embeddedness as part of sociological theory of economic action. Cultural and structural embeddedness often work together to shape the framework of economic relations, but, in an analysis of rural solicitors, we find unevenness between cultural and structural embeddedness. There are strong traits of the former, through a sense of place and belonging, but much less evidence of the latter with the structural relationships appearing relatively weak and underdeveloped. In a discussion supported by empirical data from a recent survey of rural legal practices in Wales, a number of causes are identified. The paper concludes that trends towards increasingly specialized rather than generalized legal service provision, set alongside the increasingly differentiated nature of rural space, suggest that the longer-term sustainability of rural legal practices may require both greater investment at the level of structural embeddedness alongside continuing reinvestment at the cultural level. [source] Genetic tests of the taxonomic status of the ring-tailed lemur (Lemur catta) from the high mountain zone of the Andringitra Massif, MadagascarJOURNAL OF ZOOLOGY, Issue 1 2000Anne D. Yoder Abstract A recent survey of the high-mountain zone of the Madagascar Parc National (PN) d'Andringitra revealed the presence of an apparently isolated troop of the ring-tailed lemur Lemur catta. These animals display phenotypic and ecological characteristics that are unusual for the monotypic genus Lemur, thus raising the possibility that they are members of a different undescribed species. We present analyses of two mitochondrial genes to test the hypothesis that L. catta from Andringitra should be considered a distinct species. The results indicate that taxonomic revision is not warranted under the expectations of the phylogenetic, coalescent, or biological species concepts. Rather, the genetic patterns observed among the Andringitra and lowland mitochondrial haplotypes are consistent with those expected for a single species. [source] Differences in RBV strategic factors and the need to consider opposing factors in turnaround outcomesMANAGERIAL AND DECISION ECONOMICS, Issue 4 2008Richard J. Arend The resource-based view-related empirical literature has focused on one-industry,one-focal-resource studies to provide support for its core tenets. We complement that literature with a first empirical analysis of multiple strategic factors, including opposing factors, and covering multiple industries, based on a recent survey of turnaround professionals. We focus on two issues. First, we explore what factor characteristics correlate to differences in the level of impact on firm performance that different types of factors have. Second, we explore the balance between opposing strategic factors (i.e., beneficial versus detrimental factors) relating to which turnaround outcome occurs. Copyright © 2008 John Wiley & Sons, Ltd. [source] Daphnia comes of age: an ecological model in the genomic eraMOLECULAR ECOLOGY, Issue 7 2008SARAH SCHAACK Abstract Scientists in various subdisciplines of biology have long relied on model organisms to push the frontiers of knowledge forward as far as possible in their specific field. Today, interdisciplinary science requires model organisms that can push our understanding on multiple frontiers and help us formulate and address more complex questions. Members of the genus Daphnia represent just such an interdisciplinary model. Daphnia are aquatic microcrustaceans (also known as waterfleas) that have long been central to the study of ecology and toxicology and have recently been developed as a genomic model. A recent survey of both nuclear and mitochondrial markers in populations of the Daphnia pulex complex from high-altitude lakes in South America (Mergeay et al. 2008, this issue) provides an excellent example of how genetic data and ecological information can be used to push the boundaries of our understanding in molecular ecology. In this species complex, extensive hybridization has occurred resulting in polyploidization and, consequently, asexuality. Their data reveal high levels of genetic diversity, incongruence in phylogenetic signal among genomes (nuclear and mitochondrial), cryptic species in the complex, and a new model for the historical spread of the species throughout the Americas. Their data indicate that genome-level changes have occurred in this species which have profound consequences in an ecological context, the implications of which can be more fully appreciated because of our extensive knowledge of the ecology and natural history of the genus Daphnia. [source] Measuring rDNA diversity in eukaryotic microbial systems: how intragenomic variation, pseudogenes, and PCR artifacts confound biodiversity estimatesMOLECULAR ECOLOGY, Issue 24 2007DANIEL J. THORNHILL Abstract Molecular approaches have revolutionized our ability to study the ecology and evolution of micro-organisms. Among the most widely used genetic markers for these studies are genes and spacers of the rDNA operon. However, the presence of intragenomic rDNA variation, especially among eukaryotes, can potentially confound estimates of microbial diversity. To test this hypothesis, bacterially cloned PCR products of the internal transcribed spacer (ITS) region from clonal isolates of Symbiodinium, a large genus of dinoflagellates that live in symbiosis with many marine protists and invertebrate metazoa, were sequenced and analysed. We found widely differing levels of intragenomic sequence variation and divergence in representatives of Symbiodinium clades A to E, with only a small number of variants attributed to Taq polymerase/bacterial cloning error or PCR chimeras. Analyses of 5.8S-rDNA and ITS2 secondary structure revealed that some variants possessed base substitutions and/or indels that destabilized the folded form of these molecules; given the vital nature of secondary structure to the function of these molecules, these likely represent pseudogenes. When similar controls were applied to bacterially cloned ITS sequences from a recent survey of Symbiodinium diversity in Hawaiian Porites spp., most variants (~87.5%) possessed unstable secondary structures, had unprecedented mutations, and/or were PCR chimeras. Thus, data obtained from sequencing of bacterially cloned rDNA genes can substantially exaggerate the level of eukaryotic microbial diversity inferred from natural samples if appropriate controls are not applied. These considerations must be taken into account when interpreting sequence data generated by bacterial cloning of multicopy genes such as rDNA. [source] New developments in insecticide resistance in the glasshouse whitefly (Trialeurodes vaporariorum) and the two-spotted spider mite (Tetranychus urticae) in the UKPEST MANAGEMENT SCIENCE (FORMERLY: PESTICIDE SCIENCE), Issue 2 2002Kevin Gorman Abstract A recent survey of insecticide resistance in two of the most problematic pests in UK glasshouses revealed some new developments. At least some individuals in all UK samples of Trialeurodes vaporariorum that were tested resisted the insect growth regulator (IGR) buprofezin. The most strongly resistant strains were unaffected by the field application rate of this compound, and even samples from populations that had never been exposed to buprofezin contained individuals that survived the highest concentration applied (10,000,mg,litre,1). The field rate of buprofezin was shown to select for resistance through vapour action alone. The benzophenylurea teflubenzuron, an unrelated IGR, was cross-resisted by buprofezin-resistant individuals. There was no evidence of resistance to imidacloprid, but all T vaporariorum strains tested, regardless of origin, exhibited a high innate tolerance to nicotine, when compared with another whitefly species, Bemisia tabaci. Marked resistance to fenbutatin oxide and tebufenpyrad was found in single glasshouse populations of Tetranychus urticae, but these compounds and abamectin appeared to remain highly effective against all other strains collected. © 2001 Society of Chemical Industry [source] The Impact of Mass Customisation on Manufacturing Trade-offsPRODUCTION AND OPERATIONS MANAGEMENT, Issue 1 2006Brian Squire Management literature has suggested that the advent of mass customisation marks the end for trade-offs between customisation and other competitive priorities (Pine et al. 1993; Westbrook and Williamson 1993; Tu et al. 2001). However, evidence supporting this proposition is anecdotal. This paper examines the impact of product customisation on four competitive priorities, drawing upon the results of a recent survey of 102 U.K. manufacturing firms from eight industry sectors. The study indicates significant compatibility between customisation and quality, volume flexibility, delivery reliability and non-manufacturing costs. On the other hand, trade-offs remain between customisation and manufacturing costs and delivery lead times. The results contradict the initial proposition that customisation can be "free," and have important implications for firms embarking upon a mass customisation strategy. [source] Does border enforcement deter unauthorized immigration?REGULATION & GOVERNANCE, Issue 2 2007The case of Mexican migration to the United States of America Abstract This paper asks whether the migration decisions of unauthorized Mexican immigrants to the USA have been influenced by stronger US border enforcement efforts since 1993 that have sharply increased the physical risk and financial cost of illegal immigration. These measures were supposed to have decreased the probability of successful entry, thereby lowering the expected benefits of migration. We carried out a logistic regression analysis of data from a recent survey of 603 returned migrants and potential first-time migrants in rural Mexico. Our findings indicate that tougher border controls have had remarkably little influence on the propensity to migrate illegally to the USA. Political restrictions on immigration are far outweighed by economic and family-related incentives to migrate. An alternative, labor-market approach to immigration control with higher probability of effectiveness is outlined. [source] Patents and Innovation in Cancer Therapeutics: Lessons from CellProTHE MILBANK QUARTERLY, Issue 4 2002Avital Bar-Shalom How scientific knowledge is translated into diagnostic and therapeutic tools is important to patients with dread diseases as well as to regulators and policymakers. Patents play a crucial role in that process. Indeed, concern that the fruits of federally funded research would languish without commercial application led to the passage of the Bayh-Dole Act (PL 96-517), which reinforced incentives to patent the results of inventions arising from federally funded research (Eisenberg 1996). Subsequently, rates of patenting among U.S. academic institutions have increased (Henderson, Jaffe, and Trajtenberg 1988). A recent survey by the Association of University Technology Managers counted 20,968 licenses and options from 175 academic institutions and 6,375 patent applications filed in fiscal year 2000 (Pressman 2002). Analysis suggests that the number of academic patents was already rising when the Bayh-Dole Act was passed in 1980 (Mowery et al. 2001), but it is clear that the act reinforced the patenting norm in research universities and mandated a technology transfer infrastructure at those universities that had not yet established a technology licensing office. This article discusses the interaction between intellectual property and cancer treatment. CellPro developed a stem cell separation technology based on research at the Fred Hutchinson Cancer Center. A patent with broad claims to bone marrow stem cell antibodies had been awarded to Johns Hopkins University and licensed to Baxter Healthcare under the 1980 Bayh-Dole Act to promote commercial use of inventions from federally funded research. CellPro got FDA approval more than two years before Baxter but lost patent infringement litigation. NIH elected not to compel Hopkins to license its patents to CellPro. CellPro went out of business, selling its technology to its competitor. Decisions at both firms and university licensing offices, and policies at the Patent and Trademark Office, NIH, and the courts influenced the outcome. [source] Is there just one lesion?ANZ JOURNAL OF SURGERY, Issue 10 2009The need for whole body skin examination in patients presenting with non-melanocytic skin cancer Abstract Background:, In patients presenting with non-melanoma skin cancer (NMSC) the frequency of concurrently presenting tumours is poorly documented. Whole body skin examination is recommended but in a recent survey of Australian General Practitioners and skin cancer clinics doctors it was infrequently performed. The aim of this study was to examine the incidence of concurrent skin cancer at initial presentation and therefore to examine the need for whole body skin examination for NMSC presentations. Method:, One hundred consecutive patients with a referral diagnosis indicative of NMSC were examined. Data was analysed as to the referring doctor's diagnosis, whole body skin examination findings and histology of excised lesions. Epidemiological data was obtained by patient questionnaire. Results:, One hundred patients, 41 males and 59 females, with a mean age of 70 years (range 39,91 years) underwent whole body skin examination. Sixty-seven per cent of patients were found to have additional lesions requiring treatment, 46% skin cancers (30 patients basal cell carcinomas, five squamous cell carcinomas, seven basal and squamous cell carcinomas, two lentigo maligna, two adenexal tumours) and 21% solar keratoses. Thirty-four of the additional lesions detected were in areas covered by clothing. Sixty-eight patients had a past history of skin cancer excision. Conclusions:, In the Australian patient population, the need for whole body skin examination is essential to avoid missing concurrent lesions. Ongoing surveillance is also essential as these patients have a high risk of developing future NMSC. [source] Have Unions Turned the Corner?BRITISH JOURNAL OF INDUSTRIAL RELATIONS, Issue 2 2006New Evidence on Recent Trends in Union Recognition in UK Firms This paper reports results from a recent survey conducted on unionization in over 650 firms in the private sector in the UK. The survey shows that since 1997 there has been a slight fall in derecognition, but a relatively large increase in union recognition. This increase in new recognition agreements is consistent with the idea that the incoming Labour government had a positive effect on the ability of unions to gain recognition, either through the 1999 legislation or more indirectly through changing the political climate. [source] | ||||||||||||||||||||||||||||||||||