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Recall Test (recall + test)
Kinds of Recall Test Selected AbstractsThe safety and tolerability of duloxetine in depressed elderly patients with and without medical comorbidityINTERNATIONAL JOURNAL OF CLINICAL PRACTICE, Issue 8 2007T. N. Wise Summary Aim and methods:, The impact of medical comorbidity on the efficacy and tolerability of duloxetine in elderly patients with major depressive disorder (MDD) was investigated in this study. Data were obtained from a multicentre, randomised, double-blind, placebo-controlled study in 311 patients with MDD aged 65,89. The primary outcome measure was a prespecified composite cognitive score based on four cognitive tests: (i) Verbal Learning and Recall Test; (ii) Symbol Digit Substitution Test; (iii) 2-Digit Cancellation Test and (iv) Letter-Number Sequencing Test. Secondary measures included the Geriatric Depression Scale (GDS), 17-Item Hamilton Depression Scale (HAMD17), Clinical Global Impression-Severity (CGI-S) Scale, Visual Analogue Scale (VAS) for pain and 36-Item Short Form Health Survey (SF-36). Tolerability measures included adverse events reported as the reason for discontinuation and treatment-emergent adverse events (TEAEs). The consistency of the effect of duloxetine vs. placebo comparing patients with and without medical comorbidity (vascular disease, diabetes, arthritis or any of these) was investigated. Results:, Overall, duloxetine 60 mg/day demonstrated significantly greater improvement compared with placebo for the composite cognitive score, GDS and HAMD17 total scores, CGI-Severity, HAMD17 response and remission rates, and some of the SF-36 and VAS measures. There were few significant treatment-by-comorbidity subgroup interactions for these efficacy variables, or for adverse events reported as the reason for discontinuation and common TEAEs. Conclusions:, The present analyses suggested that the efficacy of duloxetine on cognition and depression in elderly patients, and its tolerability, were not largely affected by the comorbidity status. These results further support the use of duloxetine in elderly patients with MDD. [source] No association between subjective memory complaints and apolipoprotein E genotype in cognitively intact elderlyINTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 12 2004Dylan G. Harwood Abstract Objective This cross-sectional study examined the relationship between subjective memory complaints and the apolipoprotein epsilon 4 allele (,4), a genetic risk factor for Alzheimer's disease (AD), among cognitively normal subjects identified from a community memory screening. Design The sample comprised 232 consecutive white non-Hispanic older adults who presented to a free community-based memory-screening program at a University affiliated memory disorders center. Participants were classified as cognitively normal based on scores on the age and educated adjusted Folstein Mini-Mental Status Exam (MMSAdj) and a brief Delayed Verbal Recall Test (DRT). Subjects were assessed for APOE genotype, subjective memory complaints (Memory Questionnaire, MQ), depressive symptoms (Hamilton Depression Rating Scale, HDRS), and history of four major medical conditions that have been associated with memory loss (stroke/transient ischemic attack [TIA], atherosclerotic heart disease, hypertension, and diabetes). A hierarchical regression analysis was performed to examine the association between APOE genotype and memory complaints after controlling for a host of potential confounding factors. Results The APOE ,4 allele frequency for cognitively normal subjects was 0.13. Subjective memory complaints were predicted by depressive symptoms and a history of stroke/TIA. They were not associated with APOE genotype, MMSAdj score, DRT score, age, education, gender, and reported history of atherosclerotic heart disease, hypertension, or diabetes. Conclusion The results did not suggest an association between subjective memory complaints and the APOE ,4 allele in this sample of cognitively intact subjects. This indicates that memory complaints may confer risk for future dementia through pathways independent of APOE genotype. The results also show that older adults with memory complaints are at increased risk for underlying depression. Copyright © 2004 John Wiley & Sons, Ltd. [source] Measures of cognitive function in persons with varying degrees of sleep-disordered breathing: the Sleep Heart Health StudyJOURNAL OF SLEEP RESEARCH, Issue 3 2002Lori L. Boland Summary Epidemiologic literature suggests that persons with clinically diagnosed sleep apnoea frequently have impaired cognitive function, but whether milder degrees of sleep-disordered breathing (SDB) are associated with cognitive dysfunction in the general population is largely unknown. Approximately 1700 subjects free of clinically diagnosed SDB underwent at-home polysomnography (PSG) as part of the Sleep Heart Health Study (SHHS) and completed three cognitive function tests within 1,2 years of their PSG: the Delayed Word Recall Test (DWR), the WAIS-R Digit Symbol Subtest (DSS), and the Word Fluency test (WF). A respiratory disturbance index (RDI) was calculated as the number of apnoeas and hypopnoeas per hour of sleep. After adjustment for age, education, occupation, field centre, diabetes, hypertension, body-mass index, use of CNS medications, and alcohol drinking status, there was no consistent association between the RDI and any of the three cognitive function measures. There was no evidence of a dose,response relation between the RDI and cognitive function scores and the adjusted mean scores by quartiles of RDI never differed from one another by more than 5% for any of the tests. In this sample of free-living individuals with mostly mild to moderate levels of SDB, the degree of SDB appeared to be unrelated to three measures of cognitive performance. [source] Impaired working memory in children with attention deficit hyperactivity disorder and their siblingsASIA-PACIFIC PSYCHIATRY, Issue 3 2010Kok Wei Wee MD (USM) MMED (PSY) (USM) Abstract Introduction: Impairment of working memory in children with attention deficit hyperactivity disorder (ADHD) has been well described. If similar impairment in working memory can be demonstrated among their siblings, this could suggest impaired working memory is a genetic component of ADHD. Methods: Fifty-seven subjects were recruited: (1) ADHD group (n=21); (2) siblings of ADHD children group (n=15); and (3) non-ADHD children with chronic medical condition as the control group (n=21). All subjects were aged between 6 and 15 years, and ADHD was diagnosed according to DSM-IV-TR. Those with other comorbidity or IQ<70 were excluded. Digit Recall was used for assessment of the phonological loop component, Maze Memory test for the visuospatial sketch pad component and Backward Digit Recall for the central executive component of working memory. Results: ADHD children and their siblings showed similar impairment and both differed from the control group on the Maze Memory test. ADHD children also showed impairment in the Digit Recall test; however, the sibling group did not differ from the control group on this test. The Backward Digit Recall score did not show any significant difference between the three groups. Discussion: Impairment of the visuospatial sketch pad component of working memory seems to cluster in ADHD children and their siblings. Thus, impairment of the visuospatial sketch pad component of working memory may point towards a genetic predisposition of ADHD. [source] Prediction of transition from cognitive impairment to senile dementia: a prospective, longitudinal studyACTA PSYCHIATRICA SCANDINAVICA, Issue 5 2003S. Artero Objective: The purpose of this investigation was to replicate the statistical approach used in a previous investigation (Toronto study) within a French population to determine the best predictive model for Alzheimer's disease (AD). Method: Data from neuropsychological tests from two prospective studies were entered into a regression model. Results: Replication of the statistical approach in the Montpellier sample produced a three-test model with a specificity of 99% and sensitivity of 73%. This model consisted of a delayed auditory verbal recall test, a construction test, a category fluency test and provides probability estimates for the transition to dementia in individual cases. Conclusion: The models derived from these two longitudinal studies provide an empirical basis for the selection of tests for the definition of mild cognitive impairment of the Alzheimer type (MCI-A). The small set of tests derived are suitable for use in general practice. [source] Caffeine (4,mg/kg) influences sustained attention and delayed free recall but not memory predictionsHUMAN PSYCHOPHARMACOLOGY: CLINICAL AND EXPERIMENTAL, Issue 4 2001William L. Kelemen Abstract This experiment was conducted to examine the influence of a moderate dose of caffeine (4,mg/kg) on delayed memory, metamemory, and sustained attention. One hundred and forty-two volunteers ingested either caffeine or placebo during a study session which included three different memory tasks (free recall, cued recall, and recognition), and they made predictions of future memory performance. On day 2, participants again ingested either caffeine or placebo and completed memory tests. Sustained attention performance was measured on both days, and caffeine reliably improved hit rates and response latencies. A reliable drug-state interaction was detected only in the free recall test of memory. Caffeine did not affect the magnitude or accuracy of memory predictions, but there was some evidence that expectancies about caffeine were related to cognitive performance. Overall, caffeine's impact on memory and metamemory was not robust in this study. Copyright © 2001 John Wiley & Sons, Ltd. [source] Comparison of recovery properties of desflurane and sevoflurane according to gender differencesACTA ANAESTHESIOLOGICA SCANDINAVICA, Issue 2 2005E. Tercan Background:, The aim of this study was to investigate the recovery properties of desflurane and sevoflurane in patients undergoing elective surgery, according to the gender differences. Methods:, In the study, 160 ASA class I,II patients aged between 20 and 60 years were included. The patients were assigned into two groups according to their gender, and these groups were randomly divided into two groups according to a selected volatile anaesthetic agent. Intraoperative bispectral index, time of postoperative achievement for end-tidal concentrations of volatile agents to decline 50% (ET-AA%50), time for extubation, time for eye opening and orientation, and time for bispectral index values to reach control values were recorded. Aldrete scores and error points of a delayed memory recall test were determined. Results:, Desflurane groups had a shorter ET-AA%50 time, extubation and eye-opening time in male and female patients compared to the sevoflurane groups, and these results were statistically significant (P < 0.05). In both the desflurane and sevoflurane groups, ET-AA%50 time, extubation and eye-opening time were shorter in male patients than in female patients, and these results were also statistically significant (P < 0.05). There were no significant differences among the groups in terms of Aldrete scores and error points of delayed memory recall test (P > 0.05). Conclusion:, In conclusion, early recovery time was shorter in male patients compared to female patients in both the desflurane and sevoflurane groups. Additionally, in the desflurane groups it was shorter in the sevoflurane groups for both genders. [source] Feigning amnesia undermines memory for a mock crimeAPPLIED COGNITIVE PSYCHOLOGY, Issue 5 2004Kim Van Oorsouw Using scripts, previous studies by Christianson and co-workers have suggested that simulating amnesia undermines memory. Relying on a more realistic mock crime paradigm, the current study examined whether feigning amnesia has memory-undermining effects. After committing a mock crime, one group of participants (n,=,21) was instructed to simulate amnesia for the event. Their performance on immediate free recall tests was compared to that of participants (n,=,20) who were instructed to respond honestly during free recall. After one week, simulators, honestly responding controls, and a second control group (n,=,20) that had not undergone immediate memory testing after the pertinent event completed free recall tests. This time, all participants were instructed to perform as well as they could. At the follow-up free recall test, both ex-simulators and controls who underwent the memory testing for the first time performed significantly worse than the honestly responding controls. Thus, the current study supports the idea that simulating amnesia in order to evade responsibility for a crime has detrimental effects on true memory of the crime. Our results also suggest that this effect can best be understood in terms of lack of rehearsal. Copyright © 2004 John Wiley & Sons, Ltd. [source] Memory conformity: can eyewitnesses influence each other's memories for an event?APPLIED COGNITIVE PSYCHOLOGY, Issue 5 2003Fiona Gabbert The current study investigated memory conformity effects between individuals who witness and then discuss a criminal event, employing a novel procedure whereby each member of a dyad watches a different video of the same event. Each video contained unique items that were thus seen only by one witness. Dyads in one condition were encouraged to discuss the event before each witness (individually) performed a recall test, while in a control condition dyads were not allowed to discuss the event prior to recall. A significant proportion (71%) of witnesses who had discussed the event went on to mistakenly recall items acquired during the discussion. There were no age-related differences in susceptibility to these memory conformity effects in younger (18,30 years) as compared to older (60,80 years) participants. Possible social and cognitive mechanisms underlying the distortions of memory due to conformity are discussed. Copyright © 2003 John Wiley & Sons, Ltd. [source] Metamemory and reality monitoringAPPLIED COGNITIVE PSYCHOLOGY, Issue 4 2002Amy Kelly Metamemory judgements and reality monitoring judgements were compared for real and imagined stimuli. Line drawings of everyday items were either perceived or imagined in differing ratios, to (a) investigate people's ability to predict the class of item that would be better recalled (Judgements of Learning, JOL), and the class of item which would be better sourced (Judgements of Source, JOS) in a future recall test, and (b) test the hypothesis that participants would show a bias towards calling remembered items real when the source had been forgotten. Although participants' JOLs indicated that they believed real items would be more memorable than imagined, in both experiments a larger proportion of items from either class (real or imagined) was only recalled when presentation modality was less frequent for that class. By contrast, JOSs were no different for real or imagined items, even though source attribution was more accurate for real than imagined items. An attribution of memories to real rather than to imagined events that often occurs when participants are unsure about the source (labelled a ,bias towards the real') was due to phenomenological qualities of the memories. The results are discussed in terms of Johnson and Raye's (1981) reality-monitoring model. Copyright © 2002 John Wiley & Sons, Ltd. [source] Memory with emotional content, brain amygdala and Alzheimer's diseaseACTA NEUROLOGICA SCANDINAVICA, Issue 2 2009R. R. Schultz Objectives,,, A highly adaptive aspect of human memory is the enhancement of explicit, consciously accessible memory by emotional stimuli. We studied the performance of Alzheimer's disease (AD) patients and elderly controls using a memory battery with emotional content, and we correlated these results with the amygdala and hippocampus volume. Methods,,, Twenty controls and 20 early AD patients were subjected to the International Affective Picture System (IAPS) and to magnetic resonance imaging-based volumetric measurements of the medial temporal lobe structures. Results,,, The results show that excluding control group subjects with 5 or more years of schooling, both groups showed improvement with pleasant or unpleasant figures for the IAPS in an immediate free recall test. Likewise, in a delayed free recall test, both the controls and the AD group showed improvement for pleasant pictures, when education factor was not controlled. The AD group showed improvement in the immediate and delayed free recall test proportional to the medial temporal lobe structures, with no significant clinical correlation between affective valence and amygdala volume. Conclusion,,, AD patients can correctly identify emotions, at least at this early stage, but this does not improve their memory performance. [source] Verbal memory performance improved via an acute administration of D -amphetamineHUMAN PSYCHOPHARMACOLOGY: CLINICAL AND EXPERIMENTAL, Issue 5 2007Inge Zeeuws Abstract Background An improved long-term retention of verbal memory was observed after an acute D -amphetamine administration. It was proposed that D -amphetamine modulates consolidation, but a possible drug effect on retrieval could not be rejected. Objectives We want to provide additional support for the consolidation hypothesis, and investigate whether an influence on intervening retrieval can be refuted. Methods Thirty-six male paid volunteers participated in a double blind, counterbalanced, placebo-controlled design in which the number of intermediate free recall tests was manipulated. Results A significant D -amphetamine facilitation effect on recall performance emerged 1 h and 1 day after list learning. In line with the consolidation hypothesis, no effect was found on immediate tests. Importantly, the number of intermediate retrievals did not affect the magnitude of the drug effect, suggesting that the D -amphetamine facilitation effect is independent of retrieval. Conclusion The D -amphetamine facilitation effect on verbal memory does not involve a modulation of the initial encoding or short-term memory (STM) processes. Moreover, the drug does not enhance long-term retention by acting on intervening retrieval processes. The current findings are in line with the conjecture of an involvement of the consolidation process in the D -amphetamine facilitation effect on verbal memory in healthy humans. Copyright © 2007 John Wiley & Sons, Ltd. [source] Basis of metamemory judgments for text with multiple-choice, essay and recall tests,APPLIED COGNITIVE PSYCHOLOGY, Issue 2 2009Ruth H. Maki Accuracy of metamemory for text was compared for multiple-choice, essay and recall tests. Essay and recall tests were scored with Latent Semantic Analysis (LSA), number of correct idea units and number of word matches. Each measure was correlated with college students' predictions and posttest confidence judgments across texts to determine metamemory accuracy. Metamemory accuracy varied for different types of tests with multiple-choice tests generally producing greater accuracy than essay tests. However, metamemory accuracy for essay and recall tests depended on the measure used to score them. Number of correct idea units produced the highest metamemory accuracy, word matches produced an intermediate level, and LSA produced the lowest accuracy. Students used the quantity of output in their judgments, so performance measures that related most strongly to quantity matched judgments better than measures based on answer quality. The results are compatible with an accessibility account of judgments about performance on text. Copyright © 2008 John Wiley & Sons, Ltd. [source] Feigning amnesia undermines memory for a mock crimeAPPLIED COGNITIVE PSYCHOLOGY, Issue 5 2004Kim Van Oorsouw Using scripts, previous studies by Christianson and co-workers have suggested that simulating amnesia undermines memory. Relying on a more realistic mock crime paradigm, the current study examined whether feigning amnesia has memory-undermining effects. After committing a mock crime, one group of participants (n,=,21) was instructed to simulate amnesia for the event. Their performance on immediate free recall tests was compared to that of participants (n,=,20) who were instructed to respond honestly during free recall. After one week, simulators, honestly responding controls, and a second control group (n,=,20) that had not undergone immediate memory testing after the pertinent event completed free recall tests. This time, all participants were instructed to perform as well as they could. At the follow-up free recall test, both ex-simulators and controls who underwent the memory testing for the first time performed significantly worse than the honestly responding controls. Thus, the current study supports the idea that simulating amnesia in order to evade responsibility for a crime has detrimental effects on true memory of the crime. Our results also suggest that this effect can best be understood in terms of lack of rehearsal. Copyright © 2004 John Wiley & Sons, Ltd. [source] | ||||||||||||||||||||||