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Autism Research (autism + research)
Selected AbstractsThe International Meeting for Autism ResearchAUTISM RESEARCH, Issue 1 2009Article first published online: 16 MAR 200 No abstract is available for this article. [source] The International Meeting for Autism ResearchAUTISM RESEARCH, Issue 6 2008Article first published online: 30 DEC 200 No abstract is available for this article. [source] Our vision for Autism ResearchAUTISM RESEARCH, Issue 2 2008Anthony Bailey [source] Advances in autism researchDEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 3 2005Mary Coleman No abstract is available for this article. [source] Autism genetics: strategies, challenges, and opportunitiesAUTISM RESEARCH, Issue 1 2008Brian J. O'Roak Abstract Although genes have long been appreciated to play a critical role in determining the risk for pervasive developmental disorders, the specific transcripts contributing to autism spectrum disorders (ASD) have been quite difficult to characterize. However, recent findings are now providing the first insights into the molecular mechanisms underlying these syndromes and have begun to shed light on the allelic architecture of ASD. In this article, we address what is known about the relative contributions of various types of genetic variation to ASD, consider the obstacles facing gene discovery in this complex disorder, and evaluate the common methodologies employed to address these issues, including linkage, molecular and array-based cytogenetics, and association strategies. We review the current literature, highlighting recent findings implicating both rare mutations and common genetic polymorphisms in the etiology of autism. Finally, we describe key advances in genomic technologies that are transforming all areas of human genetics and consider both the opportunities and challenges for autism research posed by these rapid changes. [source] Autism spectrum disorders: clinical and research frontiersCHILD: CARE, HEALTH AND DEVELOPMENT, Issue 5 2008Richard Reading Autism spectrum disorders: clinical and research frontiers . CaronnaE. B., MilunskyJ. M. & Tager-FlusbergH. ( 2008 ) Archives of Disease in Childhood , 93 , 518 , 523 . DOI: 10.1136/adc.2006.115337 . Autism spectrum disorders (ASD) are common neurodevelopmental disorders that occur along a broad continuum of severity with impairments in social interactions, communication and behaviour. This review highlights recent advances in autism research that shed light on the causes of the disorder and that have implications for clinical practice. It focuses on (1) the rising prevalence of ASD with attention given to recent epidemiological studies, (2) important genetic discoveries that may affect clinical evaluation of children with ASD, (3) active areas of research in cognitive neuroscience that seek to explain the underlying mechanisms of a complex disorder and (4) important studies on clinical populations with implications for screening and early identification of infants and toddlers with ASD. [source] | ||||||||||