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Real Progress (real + progress)
Selected AbstractsGenetics of anxiety disorders: the complex road from DSM to DNA,DEPRESSION AND ANXIETY, Issue 11 2009Jordan W. Smoller M.D. Sc.D. Abstract Anxiety disorders are among the most common psychiatric disorders, affecting one in four individuals over a lifetime. Although our understanding of the etiology of these disorders is incomplete, familial and genetic factors are established risk factors. However, identifying the specific casual genes has been difficult. Within the past several years, advances in molecular and statistical genetic methods have made the genetic dissection of complex disorders a feasible project. Here we provide an overview of these developments, with a focus on their implications for genetic studies of anxiety disorders. Although the genetic and phenotypic complexity of the anxiety disorders present formidable challenges, advances in neuroimaging and experimental animal models of anxiety and fear offer important opportunities for discovery. Real progress in identifying the genetic basis of anxiety disorders will require integrative approaches that make use of these biologic tools as well as larger-scale genomic studies. If successful, such efforts may yield novel and more effective approaches for the prevention and treatment of these common and costly disorders. Depression and Anxiety, 2009. © 2009 Wiley-Liss, Inc. [source] PERFORMANCE MANAGEMENT AND BEST VALUE AUDIT IN SCOTLAND: A RESEARCH NOTE ON THEORY AND PRACTICEFINANCIAL ACCOUNTABILITY & MANAGEMENT, Issue 4 2008Arthur Midwinter This paper appraises the theory and practice of Best Value Audit in Scotland, and in particular the central assumption that a robust performance management system is essential for continuous improvement in service delivery, within a rational planning model of governance. The reviews of Best Value Audit in practice reveal important gaps between theory and practice, with an overemphasis on monitoring process rather than performance. There is, therefore, considerable scope to reduce the demands of the audit process on local government, and Best Value Audit, needs to move from a theoretical model to an evidence-based model of good practice if real progress is to be made. [source] Endobronchial ultrasound: real progress or just a new toy?INTERNAL MEDICINE JOURNAL, Issue 2 2008T. J. Williams No abstract is available for this article. [source] How Can the United States Take the Initiative in the Current North Korean Nuclear Crisis?PACIFIC FOCUS, Issue 2 2005Jin H. Pak On September 19, 2005, the last day of the fourth round of six-party talks, a deal was announced in which North Korea pledged to end its nuclear program in return for a number of concessions. Within 24 hours of that announcement, North Korea clarified its position by stating that the United States "should not even dream" it would dismantle its nuclear weapons until it receives a light-water nuclear reactor. Despite four rounds of six-party talks over a three year period, it seems that almost no real progress has been made, except for North Korea; US intelligence officials estimate that North Korea could have made as many as 8 or 9 nuclear weapons already. So it seems North Korea has cleverly increased its bargaining position vis-à-vis the United States. As lengthy negotiations over the provision of a Light Water Reactor (LWR) will undoubtedly ensue, it can use that time to steadily increase its nuclear deterrent. Why did the United States agree to this sub-optimal outcome? Why was it so difficult for the United States to exert more influence on North Korea and the other countries in the six-party talks? The answer to these questions lies in the changing trends affecting Northeast Asian security dynamics. For various reasons that this article will explain, these trends affect the ability of the United States to take the initiative in the ongoing North Korean nuclear crisis. As long as the United States fails to account for various changes in Northeast Asian regional dynamics, its strategy will to deter North Korea from continuing its nuclear program will not succeed. [source] Income Transfers Alone Won't Eradicate PovertyPOLICY STUDIES JOURNAL, Issue 4 2009Douglas J. Besharov Even in the current economic situation, in developed countries, rhetoric about cutting "poverty" is misleadingly outmoded,because it implicitly suggests that government income transfers can be the vehicle for achieving substantial reductions in poverty. Almost all Americans already live far above subsistence poverty: most because of their earnings, and the rest because of government transfer programs. This decline in material poverty is obscured by weaknesses in how the official U.S. poverty measure counts income. What is now called poverty is really "income inequality." Reducing income inequality is also a vitally important social goal, but it cannot be accomplished through income transfers alone. The authors argue that, although income transfers have a role to play in lessening the impact of material deprivation, real progress in raising incomes will require building the human capital of the economically disadvantaged. This means both increasing the earnings capacity of lower-income workers and reducing the number of female-headed families. [source] The Semiglades: The Collision of Restoration, Social Values, and the Ecosystem ConceptRESTORATION ECOLOGY, Issue 2 2010Christa L. Zweig Defining success targets in restoration and how social values affect them are two commonly discussed issues in restoration today. We believe that how success is commonly defined,with vague terms such as "healthy ecosystem" or cited as a return to a previous, historic state,needs to be reevaluated. With the increasing number of novel ecosystems, there is an increasing conflict between the ecosystem concept, social values, and restoration. This arises from the fact that ecosystems are defined by the values of the scientists describing them, necessarily constraining the ecosystem to a generally static concept. It is not directly the concept, but how it is perceived through our filter of social values that represses the creativity and innovation needed in restoration today. Within restoration, we feel that the ecosystem concept does a disservice by ignoring the increasing number of novel systems, and that hinders real progress in a time when hesitation can be costly. To best illustrate this, we offer the example of restoration of the Florida Everglades and how it has become a novel system in pattern and process. We suggest renaming the Everglades "The Semiglades" in hopes of opening a dialog to expose social/ecosystem biases and include novel landscapes in management and planning. [source] Embedding a strategic approach to river restoration in operational management processes , experiences in England,AQUATIC CONSERVATION: MARINE AND FRESHWATER ECOSYSTEMS, Issue S1 2010Chris P. Mainstone Abstract 1. The restoration of riverine habitats that have been physically modified by man has gained momentum over the past two decades, driven by a number of objectives. Formalizing the planning and implementation of such activity, however, so that it demonstrably meets national and local environmental objectives without compromising essential societal needs such as flood risk management, has proved problematic. 2. This paper addresses the operational realities of river restoration in the UK as experienced in England by the authors, and in doing so attempts to provide a vision for how strategic planning and implementation of restoration measures sensitive to these realities might be introduced. Specifically, the paper explores: the prevailing perspectives on river restoration, shaped by both legislative drivers for ecosystem and biodiversity protection and the multiple uses made of rivers, their floodplains and catchments; how decisions have tended to be made to date and how the government agencies for environmental protection and biodiversity conservation in England are planning to make decisions in the future; the key obstacles to putting in place scientifically and technically robust, large-scale, long-term, economically viable plans for river restoration; the potential for using rivers with special conservation designations for wildlife as a springboard for a strategic approach to river restoration more widely. 3. The issues hindering a strategic operational approach to river restoration in England are common to the rest of the UK and other developed countries grappling with the enormity of the river restoration challenge. To make real progress with river restoration, an operational decision-making framework is needed that promotes progressive and strategic action but at the same time gives everyone confidence that such action is realistic and worthwhile. Copyright © 2010 John Wiley & Sons, Ltd. [source] "Absolutely Irresponsible Amateurs": The Temporary Mixed Commission on Armaments, 1921,1924AUSTRALIAN JOURNAL OF POLITICS AND HISTORY, Issue 3 2008Andrew Webster Created in early 1921, the Temporary Mixed Commission on Armaments was a committee of eminent figures formed by the League of Nations to consider the problem of international disarmament in its widest aspects and to suggest potential initiatives, plans and solutions. What made it unique was that its members were specifically appointed as private individuals, unrestrained by formal instructions from governments. They were intended to be free to put forward ideas and opinions that seemed most likely to produce real progress but which might have created political turmoil if they had come from official representatives. To some contemporary observers this extraordinary degree of independence was tremendously appealing; to others, the lack of accountability on an issue of supreme importance to the national security of member states was desperately objectionable. In practice, much of the commission's work resolved into a battle between interventionist British members and resistant French members, led respectively by Lord Robert Cecil and Colonel Edouard Réquin, with its most prominent outcome being the failed 1923 draft Treaty of Mutual Assistance. A fascinating experiment in the possibilities of transnationalism within an international organization, the Temporary Mixed Commission on Armaments both exemplified the fluidity of the League of Nations in its early years and showed the limited results a transnational approach could achieve on as contentious an issue as disarmament. [source] Engineering of bypass conduits to improve patencyCELL PROLIFERATION, Issue 5 2004S. T. Rashid It has been decades since any real progress in bypass material has reached mainstream surgical practice. This review looks at possible remedies to this situation. Options considered are methods to reduce prosthetic graft thrombogenicity, including endothelial cell seeding and developments of new prosthetic materials. The promise of tissue-engineered blood vessels is examined with a specific look at how peptides can improve cell adhesion to scaffolds. [source] | ||||||||||||||||