Real Change (real + change)

Distribution by Scientific Domains


Selected Abstracts


Scaling Up AIDS Treatment in Developing Countries: A Review of Current and Future Arguments

DEVELOPMENT POLICY REVIEW, Issue 4 2005
Jens Kovsted
Until recently, antiretroviral treatment against AIDS was perceived to be beyond the reach of the majority of patients in developing countries. This situation has changed drastically as international funding for AIDS treatment has swelled to several billion dollars a year. What has brought about this change? Analysis of the merit of six arguments often put forward against scaling up AIDS treatment in developing countries makes it clear that the most significant (and perhaps only) real change has been the large reduction in the price of the drugs. Although affordability is obviously a central issue, it is noticeable that most of the remaining arguments continue to be unresolved. This underlines the dangers of proceeding too fast towards treatment goals. [source]


Changes in Quality of Life in Epilepsy: How Large Must They Be to Be Real?

EPILEPSIA, Issue 1 2001
Samuel Wiebe
Summary: ,Purpose: The study goal was to assess the magnitude of change in generic and epilepsy-specific health-related quality-of-life (HRQOL) instruments needed to exclude chance or error at various levels of certainty in patients with medically refractory epilepsy. Methods: Forty patients with temporal lobe epilepsy and clearly defined criteria of clinical stability received HRQOL measurements twice, 3 months apart, using the Quality of Life in Epilepsy Inventory-89 and -31 (QOLIE-89 and QOLIE-31), Liverpool Impact of Epilepsy, adverse drug events, seizure severity scales, and the Generic Health Utilities Index (HUI-III). Standard error of measurement and test-retest reliability were obtained for all scales and for QOLIE-89 subscales. Using the Reliable Change Index described by Jacobson and Truax, we assessed the magnitude of change required by HRQOL instruments to be 90 and 95% certain that real change has occurred, as opposed to change due to chance or measurement error. Results: Clinical features, point estimates and distribution of HRQOL measures, and test-retest reliability (all > 0.70) were similar to those previously reported. Score changes of ±13 points in QOLIE-89, ±15 in QOLIE-31, ±6.3 in Liverpool seizure severity,ictal, ±11 in Liverpool adverse drug events, ±0.25 in HUI-III, and ±9.5 in impact of epilepsy exclude chance or measurement error with 90% certainty. These correspond, respectively, to 13, 15, 17, 18, 25, and 32% of the potential range of change of each instrument. Conclusions: Threshold values for real change varied considerably among HRQOL tools but were relatively small for QOLIE-89, QOLIE-31, Liverpool Seizure Severity, and adverse drug events. In some instruments, even relatively large changes cannot rule out chance or measurement error. The relation between the Reliable Change Index and other measures of change and its distinction from measures of minimum clinically important change are discussed. [source]


Linguistics in a Primary School

LINGUISTICS & LANGUAGE COMPASS (ELECTRONIC), Issue 4 2007
Kristin Denham
In this article, I discuss a linguistics course that I have been teaching for the past 3 years in a multiage primary school classroom. This experience has led to work in other schools, has changed the way I teach introductory linguistics courses for teachers, and has led to the development of materials and curricula for use in K-12 classrooms. I hope the sharing of these experiences will help to effect real change in the way in which knowledge about language is taught in K-12 classrooms in the USA. [source]


PARADIGMS BEHIND (AND BEFORE) THE MODERN CONCEPT OF RELIGION

HISTORY AND THEORY, Issue 4 2006
CATHERINE BELL
ABSTRACT This essay identifies five paradigms that are basic to understanding the historical emergence and uses of the generic idea of "religion" in the Christian cultures of Europe and America. The spread of this concept has been sufficiently thorough in recent centuries as to make religion appear to be a "social fact," to use Durkheim's phrase, rather than so many cultural expressions and different social practices. The supremacy of Euro-American culture,and an academy still saturated with Christian ideas,has enjoined other cultures and forms of religiosity to conform to this idea of religion; for these cultures contentment with the status quo can vie with the anxieties of influence, including "modernization." The key paradigms discussed are the following: Christianity as the prototype; religion as the opposite of reason; the modern formulation of "world religions"; the cultural necessity of religion; and critical analysis of the Western "construction" of religion. These paradigms demonstrate the limits on theoretical variety in the field, the difficulty in making real changes in set ways of thinking, and productive foci for interdisciplinary methods of study. [source]


Avoidable burden of disease: conceptual and methodological issues in substance abuse epidemiology

INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH, Issue 4 2006
Jürgen Rehm
Abstract Determining the proportion of avoidable disease burden attributable to substance use is important for both policy development and intervention implementation. Current epidemiological theory has in principle provided a method to estimate avoidable burden of disease and the available statistical tools can provide first rough estimates. The method described in this paper, and its statistical procedures, are exemplified to estimate avoidable burden of tobacco-related disease in Canada. However, further effort is needed to find solutions in the methodological details, namely exposure measurement, risk factor multidimensionality, estimation of changes in exposure distribution over time, and estimation of risk relationships from multiple exposures changing over time with multiple endpoints (causal webs). The impetus to begin refining methods to obtain better starting points for estimating avoidable burden of disease is obvious and should be carried through in order to see real changes through evidence-based policy and intervention. Copyright © 2006 John Wiley & Sons, Ltd. [source]


Assembling Justice Spaces: The Scalar Politics of Environmental Justice in North-east England

ANTIPODE, Issue 4 2009
Karen Bickerstaff
Abstract:, In contrast to the US environmental justice movement, which has been successful in building a networked environmentalism that recognises,and has impacted upon,national patterns of distributional (in)equalities, campaigns in the UK have rarely developed beyond the local or articulated a coherent programme of action that links to wider socio-spatial justice issues or effects real changes in the regulatory or political environment. Our purpose in this paper is to extend research which explores the spatial politics of mobilisation, by attending to the multi-scalar dynamics embedded in the enactment of environmental justice (EJ) in north-east England. It is an approach that is indebted to recent work on the scalar politics of EJ, and also to the network ideas associated with actor-network theory (ANT)-inspired research on human,nature relations. Our account provides preliminary reflections on the potential for an "assemblage" perspective which draws together people, texts, machines, animals, devices and discourses in relations that collectively constitute,and scale,EJ. To conclude, and building upon this approach, we suggest future research avenues that we believe present a promising agenda for critical engagement with the production, scaling and politics of environmental (in)justice. [source]