Home About us Contact
|
Home About us Contact | ||
|
|
||
Reader's Attention (reader + attention)
Selected AbstractsA Neglected Account of PerceptionDIALECTICA, Issue 3 2008Tom Stoneham I aim to draw the reader's attention to an easily overlooked account of perception, namely that there are no perceptual experiences, that to perceive something is to stand in an external, purely non-Leibnizian relation to it. I introduce the Purely Relational account of perception by discussing a case of it being overlooked in the writings of G.E. Moore, though we also find the same move in J. Cook Wilson, so it has nothing to do with an affection for sense-data. I then discuss the relation between the PR account and recent disjunctive accounts of perceptual experience, and note that the PR account has some claim to be the only one that truly respects the directness of perception. The paper does not aspire to persuade the reader of the correctness of the neglected PR account, merely that it should be treated as a serious candidate in philosophical debates about perception. [source] Teaching Foreign Policy with MemoirsINTERNATIONAL STUDIES PERSPECTIVES, Issue 2 2002Terry L. Deibel Excerpts from the memoirs of high foreign policy officials, if carefully selected and structured, can be a valuable resource in the teaching of diplomatic history, American foreign policy, and international relations. Two decades of teaching a memoirs-only course to mid-career military officers and foreign affairs professionals in a seminar discussion format reveals many of their advantages. Memoirs are interesting reading that rarely fail to engage a reader's attention; they impart detailed knowledge of historical events; they provide a rich understanding of process and the neglected area of policy implementation; like case studies, they let students build vicarious experience in policymaking and execution; and they often provide what Alexander George called "policy-relevant generalizations." While lack of objectivity can be a serious drawback of first-person accounts, it provides its own lessons on the nature of history and can be offset by using multiple accounts of the same events and by combining memoirs with documents and historical works, or countering analytical studies. Although picking the most interesting and worthwhile excerpts, getting them in students' hands, and accommodating their length within the boundaries of a standard college course are additional challenges, professors who take them on should find that memoirs add a new level of excitement and realism to their courses. [source] Pharmaceutical and pharmacological importance of peptide transportersJOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATI ONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Issue 5 2008Matthias Brandsch Peptide transport is currently a prominent topic in membrane research. The transport proteins involved are under intense investigation because of their physiological importance in protein absorption and also because peptide transporters are possible vehicles for drug delivery. Moreover, in many tissues peptide carriers transduce peptidic signals across membranes that are relevant in information processing. The focus of this review is on the pharmaceutical relevance of the human peptide transporters PEPT1 and PEPT2. In addition to their physiological substrates, both carriers transport many ,-lactam antibiotics, valaciclovir and other drugs and prodrugs because of their sterical resemblance to di- and tripeptides. The primary structure, tissue distribution and substrate specificity of PEPT1 and PEPT2 have been well characterized. However, there is a dearth of knowledge on the substrate binding sites and the three-dimensional structure of these proteins. Until this pivotal information becomes available by X-ray crystallography, the development of new drug substrates relies on classical transport studies combined with molecular modelling. In more than thirty years of research, data on the interaction of well over 700 di- and tripeptides, amino acid and peptide derivatives, drugs and prodrugs with peptide transporters have been gathered. The aim of this review is to put the reports on peptide transporter-mediated drug uptake into perspective. We also review the current knowledge on pharmacogenomics and clinical relevance of human peptide transporters. Finally, the reader's attention is drawn to other known or proposed human peptide-transporting proteins. [source] Experiencing psychiatric diagnosis: client perspectives on being named mentally ill,JOURNAL OF PSYCHIATRIC & MENTAL HEALTH NURSING, Issue 6 2003Y. M. HAYNE rn phd In this article is reported result of a phenomenological study whereby privileged view was gained into the lives of persons who had experienced receiving a diagnosis which named ,severe and enduring mental illness'. Thematic analysis yielded the four essential themes of diagnosis as the experience of ,a knowledge that knows', ,destructive (gift) of difference', ,making visible the invisible' and ,making knowledge knowledgeable'. Each of the themes is discussed under its own heading in this paper as a means for describing the nature of ,experiencing psychiatric diagnosis'. Effort is made to provide glimpse into the ,lifeworld' of being diagnosed mentally ill, and the reader's attention is directed to a particular kind of power that exists in the medical language of diagnoses. Discernment is highlighted as most consequential to an ,action sensitive practice' and a case is made for care-providers in psychiatric-mental health care to be sensitized to how medical terminology is experienced and the need to strive for balance within the ,economy of power' contained in these specialized words. [source] Language on the Verge of Death: On Language and Language Criticism in Badenheim 1939 by Aharon AppelfeldORBIS LITERARUM, Issue 3 2004Chaya Shacham The question of language became a central issue in writing after the Holocaust, especially for those for whom the years of the Second World War were formative in both their personal lives and their becoming writers. The Hebrew writer Aharon Appelfeld is one of them. This study focuses on the problem of language and language criticism in Appelfeld's novella Badenheim 1939 (1975). Language is in fact the covert theme of the novella. The work, which describes the last summer in an Austrian resort before the deportation of its Jews to Poland, is replete with metalanguage whose purpose is to draw the reader's attention to the language and its status in the work. The essay follows and analyses the effects on language made by the characters' experiences (weakening, loss of meaning, loss of referents in the new reality and the new era in Badenheim) and suggests that the meeting point of the murderers and victims is in language corruption and distortion. The study furthermore suggests that from the novella springs the unspoken accusation against the Jewish vacationers of unintentional collaboration with the murderers by conniving in the ,laundering' of the language, which in turn contributed to the coming catastrophe. Central to the explorations of the essay is the possibility of linking Appelfeld's criticism of language with Karl Krause's critical stance on language contamination and doublespeak implied in the work. [source] | |||||||||||||