Home  About us  Contact
 

Reactive Functional Groups (reactive + functional_groups)

Distribution by Scientific Domains
Chemistry80%

Selected Abstracts

Enantioselective Benzylic Hydroxylation with Pseudomonas monteilii TA-5: A Simple Method for the Syntheses of (R)-Benzylic Alcohols Containing Reactive Functional Groups

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 13 2009
Yongzheng Chen
Abstract Highly enantioselective benzylic hydroxylations of benzene derivatives (1,4) containing reactive functional groups were achieved for the first time with Pseudomonas monteilii TA-5 as biocatalyst, giving the corresponding (R)-benzylic alcohols 5,8 in 93,99% ee as the only products. Preparative biotransformations were demonstrated by the biohydroxylation of 1 and 2 with resting cells of P. monteilii TA-5 to afford (R)- 5 in 94% ee and 66% yield and (R)- 6 in 94% ee and 56% yield, respectively. The highly enantioselective biohydroxylations represent a simple access to (R)-benzylic alcohols containing reactive functional groups that are useful pharmaceutical intermediates and versatile chiral building blocks. [source]

Thermolabile Groups in Metal,Organic Frameworks: Suppression of Network Interpenetration, Post-Synthetic Cavity Expansion, and Protection of Reactive Functional Groups,

ANGEWANDTE CHEMIE, Issue 27 2010
Rajesh
Aus Etwas Nichts gemacht: Eine sperrige tert -Butoxycarbonyl-Gruppe an einem Biphenyl-4,4,-dicarboxylat-Liganden unterdrückt die Durchdringung, sodass ein offenes würfelförmiges Metall-organisches Gerüst entsteht. Anschließende Abspaltung dieser Gruppe durch Thermolyse (siehe Bild) setzt eine potenziell reaktive Aminogruppe frei, vergrößert den Hohlraum (gelbe Kugel) und weitet die Porenöffnungen. [source]

Enantioselective Benzylic Hydroxylation with Pseudomonas monteilii TA-5: A Simple Method for the Syntheses of (R)-Benzylic Alcohols Containing Reactive Functional Groups

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 13 2009
Yongzheng Chen
Abstract Highly enantioselective benzylic hydroxylations of benzene derivatives (1,4) containing reactive functional groups were achieved for the first time with Pseudomonas monteilii TA-5 as biocatalyst, giving the corresponding (R)-benzylic alcohols 5,8 in 93,99% ee as the only products. Preparative biotransformations were demonstrated by the biohydroxylation of 1 and 2 with resting cells of P. monteilii TA-5 to afford (R)- 5 in 94% ee and 66% yield and (R)- 6 in 94% ee and 56% yield, respectively. The highly enantioselective biohydroxylations represent a simple access to (R)-benzylic alcohols containing reactive functional groups that are useful pharmaceutical intermediates and versatile chiral building blocks. [source]

Synthesis of Reactive Polymeric Dyes as Textile Auxiliaries

MACROMOLECULAR MATERIALS & ENGINEERING, Issue 9 2003
Angelina Altomare
Abstract New polymeric materials containing amino-substituted azobenzene chromophores and reactive functional groups and characterized by some hydrophilicity were prepared with the aim of investigating alternative textile dyeing routes. The indicated materials were obtained either by copolymerization of suitable monomers or by modification of preformed polymers. In both cases commercial 4-amino-2,,3-dimethylazobenzene (FG) was used as chromogenic compound. According to the first synthetic strategy, the methacrylamido derivative of FG was copolymerized by free radical initiation with different monomers, such as methyl methacrylate, glycidyl methacrylate, N - tert -butylacrylamide, methacrylic acid, N -vinyl-2-pyrrolidinone, and vinyl acetate. Reaction of FG with preformed polymers containing epoxy groups generally afforded crosslinked materials. On the other hand, low FG loading extents were recorded by amidation of polymers containing carboxylic groups. Indeed, almost quantitative conversions were obtained only in the reaction of FG with anhydride containing polymers. The chemical structure, molecular weight properties, and the physical-chemical characteristics of all synthesized polymeric dyes were thoroughly investigated. Some very preliminary dyeing tests of different cloth types with the prepared polymeric dyes were also performed. UV absorption spectrum of poly(FGMAA) and poly(FGMAA- co -MMA) in chloroform at 25,°C (FGMAA,=,4-methacrylamido-2,,3-dimethylazobenzene). [source]

Overcoming the Demons of Protecting Groups with Amphoteric Molecules

CHEMISTRY - A EUROPEAN JOURNAL, Issue 23 2007
Andrei
Abstract Synthetic organic chemists have long depended on protecting group manipulations when faced with the challenges of chemoselectivity and functional group incompatibility. Overcoming this dependence will improve the overall efficiency of chemical synthesis. By taking advantage of orthogonally reactive functional groups, amphoteric molecules can afford access not only to more efficient and strategic syntheses but also to the development of novel chemical transformations. [source]