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Rank Analysis (rank + analysis)
Selected AbstractsCirculating Metaphors of Sexuality, Aggression, and Power: Otto Rank's Analysis of "Conquering Cities and ,Conquering' Women",POLITICAL PSYCHOLOGY, Issue 1 2010David G. Winter First page of article [source] Sleep staging and respiratory events in refractory epilepsy patients: Is there a first night effect?EPILEPSIA, Issue 12 2008Linda M. Selwa Summary Purpose:, We performed this analysis of possible first night effects (FNEs) on sleep and respiratory parameters in order to evaluate the need for two serial night polysomnograms (PSGs) to diagnose obstructive sleep apnea (OSA) in epilepsy patients. Methods:, As part of a pilot multicenter clinical trial investigating the effects of treating sleep apnea in epilepsy, two nights of PSG recording were performed for 40 patients with refractory epilepsy and OSA symptoms. Sleep architecture was examined in detail, along with respiratory parameters including apnea/hypopnea index (AHI) and minimum oxygen saturation. Analysis included two-tailed t -tests, Wilcox sign rank analysis, and Bland Altman measures of agreement. Results:, Total sleep time differed between the two nights (night 1,363.8 min + 59.4 vs. 386.3 min + 68.6, p = 0.05). Rapid eye movement (REM) sleep and percentage of REM sleep were increased during night two (night 1: 12.3% + 5.9 vs. night 2: 15.5% + 6.2, p = 0.007), and the total minutes of slow-wave sleep (SWS) were increased (night 1: 35.6 + 60.7 vs. night 2: 46.4 + 68.1, p = 0.01). No other sleep or respiratory variables differed between the two nights. Given an AHI inclusion criterion of five apneas per hour, the first PSG identified all but one patient with OSA. Discussion:, Respiratory parameters showed little variability between the first and second nights. Sleep architecture was mildly different between the first and second PSG night. Performing two consecutive baseline PSGs to diagnose OSA may not be routinely necessary in this population. [source] Kinetics and mechanism of the hydrolytic disproportionation of iodineINTERNATIONAL JOURNAL OF CHEMICAL KINETICS, Issue 11 2004Krisztina Seb, k-Nagy Kinetics of the hydrolytic disproportionation of I2 was studied by UV,VIS spectrophotometry at 298 K and at the ionic strength 0.2 M (NaClO4) in buffered solutions in the pH range 8.91,10.50 at different initial iodide concentrations. The characterization of this reaction is fundamental for modeling oscillatory and front reactions in the presence of iodine as reactant or intermediate as well as for drinking water treatment. A matrix rank analysis confirmed three absorbing species in the beginning of the reaction, whereas later assumption of two species is enough to describe the experimental data in the visible part of the spectrum. A reaction mechanism was proposed for disproportionation by using fitting/simulation with a multipurpose program package ZiTa, by simultaneous evaluation of 17,906 points in 79 experimental curves. A parameter set was suggested, which was obtained by absolute, relative, and orthogonal fittings of the experimental data. © 2004 Wiley Periodicals, Inc. Int J Chem Kinet 36: 596,602, 2004 [source] Gene expression in chorionic villous samples at 11 weeks' gestation from women destined to develop preeclampsiaPRENATAL DIAGNOSIS, Issue 10 2008Antonio Farina Abstract Objective To evaluate the direct alterations in mRNA expression among chorionic villous samples from 11 weeks' pregnant women who would develop preeclampsia (PE) later in the pregnancy. Method Case-control study encompassing five women destined to develop PE [cases matched 1:5 for gestational age (GA) with 25 controls]. We quantified mRNA expression on tissue samples from chorionic villous sampling (CVS) of normal and PE patients. We then assessed mRNA expressions of vascular endothelial growth factor (VEGFA), VEGFA receptor 1 (Flt-1), endoglin (Eng), placental growth factor (PlGF), transforming growth factor-,1 (TGF-,1), heme oxygenase-1 (HO-1) and superoxide dismutase (SOD). Data were analyzed by nonparametric rank analysis. Results For all the mRNA species considered in this study, all the mean observed ranks in the PE group were significantly altered compared to the rank expectation among controls. mRNA for Eng and TGF-,1 were the markers with the highest degree of aberration in PE, in respect to controls. The results are consistent with those already reported for the corresponding circulating proteins. mRNA for HO-1 and SOD were instead associated with the lowest aberration. Conclusion It is assumed that the pathogenesis of PE is associated with pathophysiological alterations to trophoblasts in early gestation. Our study has directly proved that gene expressions relating to angiogenesis or oxidative stress are altered in the first trimester trophoblasts that go on to develop PE later. These results would put the basis for a possible screening method for PE by using residual CVS. Copyright © 2008 John Wiley & Sons, Ltd. [source] A Global View on Parametric and Nonparametric Approaches to the Analysis of Ordered Categorical DataBIOMETRICAL JOURNAL, Issue 1 2004Ullrich Munzel Abstract Rank approaches are very common in the analysis of ordered categorical data but can only be interpreted on an experiment-wise level. Therefore, parametric tests from linear models, although based on metric structures, are used frequently to analyze this type of data. So the questions arise 1. what parametric tests measure in this context and 2. whether the rank approach could be modified to achieve a global level of interpretation. A possible solution to question 2. offers the so called ridit approach, which is based on known reference distributions. In this paper we discuss a global view that shows how rank analysis and ridit analyses are related and how parametric procedures fit into the same framework. The use of the uniform distribution as a reference in the ridit approach gives an explanation to question 1. The asymptotic multivariate normality of the effect estimators is shown and robust test statistics are discussed. Type I and type II error rates are examined in simulation studies and the approach is applied to a toxicological example. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] Does delayed treatment shorten the life of patients with fatal choroidal melanoma?ACTA OPHTHALMOLOGICA, Issue 2009B DAMATO Purpose Metastatic death from uveal melanoma occurs in about 50% of patients many of whom experience a delay in treatment, either intentionally or accidentally. The aim of this study was to determine whether treatment delay shortens survival in patients with choroidal melanoma whose disease apparently proved fatal. Methods Patients with choroidal melanoma were included in the study if resident in mainland Britain and if deceased. Survival was analysed according to basal tumour diameter by Kaplan-Meier and Log rank analysis. Results A total of 696 patients with choroidal melanoma died. The patients had a median age of 65 years and a median basal tumour diameter of 15.0 mm. The basal tumour diameter was <10mm in 41 patients; 10-11mm in 88; 12-13mm in 108; 14-15mm in 165; 16-17mm in 123; and >17mm in 171 patients. Log-rank analysis showed no correlation between survival and basal tumour diameter in these patients (Log rank analysis, p = 0.5537). There was perhaps a trend towards longer survival in patients with a basal tumour diameter less than 10mm. Conclusion In patients with fatal uveal melanoma, there is no significant correlation between basal tumour diameter and survival time. Delay in treatment does not seem to worsen prognosis for survival significantly, except perhaps in patients with small tumours. This finding adds further support to the concept that the main objective of ocular treatment is to conserve the eye with as much useful vision as possible. Since ocular treatment can itself cause significant visual loss, the benefit of treating asymptomatic uveal melanomas is uncertain. There is scope for randomized, prospective studies of treatment versus non-treatment of patients with asymptomatic choroidal melanoma. [source] | ||||||||||