Home About us Contact
|
Home About us Contact | ||
|
|
||
Rare Condition (rare + condition)
Kinds of Rare Condition Selected AbstractsIsolated levocardia: Prenatal diagnosis and managementCONGENITAL ANOMALIES, Issue 2 2009Satoko Katsuya ABSTRACT Isolated levocardia (IL) is a rare condition of situs anomaly in which there is a normal left-sided heart (levocardia) with dextro position of the abdominal viscera. IL has been reported in children and adults with complex cardiac defects, whereas there are only few published reports regarding the prenatal diagnosis of IL. We report two prenatal cases of IL diagnosed by ultrasonography and magnetic resonance imaging (MRI). In both cases, fetal cardiac function remained within the normal range throughout pregnancy, and no treatment for the heart was required after birth. For the dextro position of abdominal viscera, one case was followed without any surgical procedure, but the other case required prophylactic operation due to malrotation of the small intestine. Although the prognosis of IL largely depends on the severity of associated cardiac anomaly, future bowel obstruction caused by intestinal malrotation may also be life-threatening. In this respect, prenatal diagnosis of IL is important, even when there is no associated cardiac structural anomaly. If IL is suspected in routine fetal ultrasonography, MRI may be recommended to obtain more detailed information on the anatomy of abdominal viscerae, and careful observation for bowel problems is required, especially after oral nutrition is started. [source] Bifid mandibular condyle: a case reportDENTAL TRAUMATOLOGY, Issue 3 2004Nur Hersek Abstract,,, A case of left bifid mandibular condyle (BMC) is reported in a 36-year-old female. The patient had a history of trauma in childhood. From the radiological examination, the left condyle was seen to have two anterioposteriorly situated heads. BMC is an extremely rare condition, where the condyle is duplicated or lobulated. The literature on BMC is reviewed, and possible cause of trauma and consequences of the anomaly are discussed. [source] Treatment of Nevoid Hyperkeratosis of the Nipple and Areola Using a Radiofrequency Surgical UnitDERMATOLOGIC SURGERY, Issue 6 2005Irfan Özyazgan MD Background. Nevoid hyperkeratosis of the nipple and areola (NHNA) is a rare condition of unknown etiology. Verrucous thickening and pigmentation of the nipple and areola are the main features of the condition. Different therapeutic options, both medical and surgical, have been described. Objective. To use a radiofrequency surgical unit to treat an NHNA case, which was unresponsive to keratolytic therapy. Materials and Methods. The lesions of the nipple and areolas were excised tangentially with a diamond-shaped electrode of a radiofrequency surgical unit under local anesthesia. Results. The patient had a good cosmetic appearance after the treatment, and there was no recurrence at the ninth postoperative month. Conclusion. Radiofrequency for tangential excision in the treatment of NHNA lesions that have not responded to medical therapy can be an alternative surgical method. [source] Successful Treatment of Dowling,Degos Disease with Er:YAG LaserDERMATOLOGIC SURGERY, Issue 8 2002Joerg Wenzel MD background. Dowling,Degos disease is a rare condition with a genetically determined disturbance of epidermal proliferation. The typical clinical picture is a reticulate pigmentation of the flexures, genital folds, and pectoral skin areas. Many different treatment options have been tried in recent years without a convincing therapeutic benefit. objective. To determine the effectiveness of Er:YAG laser in Dowling-Degos disease. methods. A 44-year-old woman suffering from Dowling-Degos disease was treated with the Er:YAG laser pulse energy between 1,000 and 1,200 mJ, three consecutive passes. results. The laser treatment led to a good clinical result. conclusion. Our case suggest that treatment with the Er:YAG laser might be a successful strategy in Dowling-Degos disease. [source] The differential diagnosis of atopic dermatitis in childhoodDERMATOLOGIC THERAPY, Issue 2 2006Alfons Krol ABSTRACT:, Atopic is the most common of the dermatitides seen in infancy and childhood, but there are numerous other diseases that can mimic the skin findings. These include seborrheic dermatitis, immunodeficiency, and psoriasis in infancy; scabies, tinea corporis infection, perioral, nummular, contact, and molluscum dermatitis in childhood. It is sometimes extremely difficult to differentiate between ichthyosis and AD, and it is also important to differentiate AD from erythrodermic conditions including acrodermatitis enteropathica, biotin deficiency, and Netherton syndrome. A rare condition in children that may mimic AD is mycosis fungoides. [source] The epidemiology of autistic spectrum disorders: is the prevalence rising?DEVELOPMENTAL DISABILITIES RESEARCH REVIEW, Issue 3 2002Lorna Wing Abstract For decades after Kanner's original paper on the subject was published in 1943, autism was generally considered to be a rare condition with a prevalence of around 2,4 per 10,000 children. Then, studies carried out in the late 1990s and the present century reported annual rises in incidence of autism in pre-school children, based on age of diagnosis, and increases in the age-specific prevalence rates in children. Prevalence rates of up to 60 per 10,000 for autism and even more for the whole autistic spectrum were reported. Reasons for these increases are discussed. They include changes in diagnostic criteria, development of the concept of the wide autistic spectrum, different methods used in studies, growing awareness and knowledge among parents and professional workers and the development of specialist services, as well as the possibility of a true increase in numbers. Various environmental causes for a genuine rise in incidence have been suggested, including the triple vaccine for measles, mumps and rubella (MMR]. Not one of the possible environmental causes, including MMR, has been confirmed by independent scientific investigation, whereas there is strong evidence that complex genetic factors play a major role in etiology. The evidence suggests that the majority, if not all, of the reported rise in incidence and prevalence is due to changes in diagnostic criteria and increasing awareness and recognition of autistic spectrum disorders. Whether there is also a genuine rise in incidence remains an open question. MRDD Research Reviews 2002;8:151,161. © 2002 Wiley-Liss, Inc. [source] SQUAMOUS CELL PAPILLOMA OF THE ESOPHAGUS: CLINICOPATHOLOGICAL STUDY OF 24 CASESDIGESTIVE ENDOSCOPY, Issue 4 2004Junya Oguma Background:, Squamous cell papilloma of the esophagus is considered to be a rare condition; however, the number of cases with this condition reported in recent years has increased, perhaps due to advances in endoscopic diagnosis. Methods:, We reviewed the clinicopathological features of 26 lesions of squamous cell papilloma of the esophagus in 24 cases seen at our hospital from 1994 to 2003. There were nine men and 15 women, with a mean age of 60.5 years (range, 31,82 years). Six patients had a history of malignant disease in the past. With regard to the presence of other lesions in the esophagus, six patients had hiatal hernia and four had gastroesophageal re,ux disease. Results:, Two patients each had two lesions of squamous cell papilloma. There were seven lesions in which in,ammatory cell in,ltration was found on hisotological examination, of which four had underlying hiatal hernia; ,ve lesions were found to have mild dysplasia on histological examination of which three had gastroesophageal re,ux disease. The median duration of follow up of the cases was 8 months (range, 1,101 months). During the follow-up period, none of the lesions showed any dramatic change of appearance or malignant transformation. Conclusion:, In principle, while it may be suf,cient to keep patients with squamous cell papilloma of the esophagus under simple follow up, the patients must be investigated to rule out malignancy of other organs, and the small probability of malignant transformation of the tumor must always be borne in mind. [source] Mediastinal bronchial artery aneurysm with hematemesisDISEASES OF THE ESOPHAGUS, Issue 4 2003A. Fukunaga SUMMARY, Mediastinal bronchial artery aneurysm is a rare condition which can lead to potentially fatal hemorrhage. In most cases it presents respiratory symptoms due to rupture into pleural parenchyma. But when it develops mediodorsally and compresses the esophagus, it may cause dysphagia or hematemesis. Here we report a case of mediastinal bronchial artery aneurysm which presented with hematemesis. Computed tomography and endoscopic ultrasound showed what seemed to be a submucosal tumor on the esophagus. We were able to correctly diagnose the aneurysm using magnetic resonance imaging and probe thoracoscopy, and were able to successfully treat with transluminal artery embolization. [source] Hypereosinophilic Syndrome Presenting with Biventricular Cardiac ThrombiECHOCARDIOGRAPHY, Issue 6 2010Ankur Lodha M.D. Hypereosinophilic syndrome is a rare condition characterized by idiopathic eosinophilia with organ system involvement. Cardiac involvement portends a less favorable prognosis as it can be complicated by development of heart failure, valvular dysfunction, and restrictive cardiomyopathy. We present a rare case of hypereosinophilic syndrome with FIP1L1/PDGFRA fusion in a 50-year-old male associated with thrombus in left and right ventricle. (Echocardiography 2010;27:E57-E59) [source] Role of Transesophageal Echocardiography in Detecting Implantable Cardioverter Defibrillator Lead InfectionECHOCARDIOGRAPHY, Issue 3 2003Sanjeev Wasson Implantable cardioverter defibrillator (ICD) lead infection is a rare condition with reported incidence of 0.2% to 16%. It usually presents with persistent bacteremia or fever of unknown origin and requires high clinical suspicion for diagnosis. Whenever ICD lead infection is suspected, transesophageal echocardiography is the diagnostic technique of choice for detection and characterization of the lesions. Lead infections are extremely difficult to manage conservatively and surgical removal of the entire defibrillator system is recommended along with antimicrobial therapy. We describe a case of recurrent staphylococci bacteremia due to an ICD lead infection in a patient with arrhythmogenic right ventricular dysplasia. (ECHOCARDIOGRAPHY, Volume 20, April 2003) [source] Cerebellar tumour presenting with pathological laughter and gelastic syncopeEUROPEAN JOURNAL OF NEUROLOGY, Issue 8 2007G. Famularo There is no report of patients in whom pathological laughter, a rare condition characterized by uncontrollable episodes of laughter usually triggered by unrelated stimuli, was ever closely associated with a loss of consciousness overtly linked with the onset of such uncontrollable laughter, also referred to as a gelastic syncope. A 53-year-old man presented with a 4-month history of syncope following intense and uncoordinated laughter. Physical and neurological examination was normal and the patient had no other typical cerebellar signs. We found a mass in the cerebellar vermis abutting the floor of the fourth ventricle, which upon histological examination after surgery proved to be an ependymoma. We emphasize that pathological laughter and gelastic syncope could represent unique and sole features of a cerebellar disorder. [source] Progressive dementia caused by Hashimoto's encephalopathy , report of two casesEUROPEAN JOURNAL OF NEUROLOGY, Issue 10 2004J. Spiegel Dementia induced by Hashimoto's encephalopathy (HE) seems to be a rare condition. We report on two patients, who revealed a syndrome consisting of a rapid progressive dementia with myocloni. In both patients, the detection of antithyroid antibodies enabled the diagnosis of HE. The symptoms receded completely during a high-dose glucocorticoid therapy. In patients with rapidly progressive dementia or with dementia of unknown origin, HE should be considered. [source] Jaw-opening dystonia (Brueghel's syndrome) associated with cavum septi pellucidi and Verga's ventricle , a case reportEUROPEAN JOURNAL OF NEUROLOGY, Issue 6 2003T. Miyaoka Jaw-opening dystonia (oromandibular dystonia with jaw-opening; Brueghel's syndrome) is a rare condition, and only a limited number of cases have been reported in the literature. However, many patients may remain undiscovered or misdiagnosed, like a patient described previously. A case (40-year-old man) of jaw-opening dystonia (oromandibular dystonia with jaw-opening; Brueghel's syndrome) is reported. In this case, brain anomalies, cavum septi pellucidi and Verga's ventricle, were observed on magnetic resonance imaging of the brain. This case and a review of the literature indicate the presence of organic factors in the etiology of Brueghel's syndrome. The etiological relationship of brain anomalies in Bruegel's syndrome is discussed. [source] Congenital asplenia and group B streptococcus sepsis in the adult: case report and review of the literatureFEMS IMMUNOLOGY & MEDICAL MICROBIOLOGY, Issue 3 2008Kumaran Thiruppathy Abstract Asplenia is associated with an increased incidence of fatal and life-threatening sepsis caused by encapsulated pathogens. Isolated congenital asplenia is a very rare condition, with only 33 cases reported in the literature. The authors report another case of this condition complicated by overwhelming Group B streptococcus sepsis secondary to paronychia that was managed successfully. [source] Candida vertebra osteomyelitis in a girl with factor X deficiencyHAEMOPHILIA, Issue 6 2005T. Gursel Summary., Candidal vertebra osteomyelitis is a rare condition which occurs primarily in immunocompromised patients. We report a 14-year-old girl with factor X deficiency who developed candida vertebra osteomyelitis during home therapy. The microorganism was probably from a contaminated peripheral cannula used for infusion of factor concentrate. This is the first such case in bleeding disorders to our knowledge. [source] Rare living hypopharyngeal foreign bodyHEAD & NECK: JOURNAL FOR THE SCIENCES & SPECIALTIES OF THE HEAD AND NECK, Issue 11 2006Matthias Kuehnemund MD Abstract Background. This is a case report about a rare hypopharyngeal foreign body causing dysphagia, dyspnea, and hemoptysis as well as melena: an ingested leech. The patient was in this condition for more than 1 week. Methods. The ingested leech, attached to the right piriform fossa partially obstructing the larynx, had to be removed under general anesthesia. Results. After removal, no further symptoms occurred. The leech was identified as the species Theromyzon tessulatum. Conclusions. Human infestation of a leech in the upper aerodigestive tract is a very rare condition in urban areas. The current literature is reviewed and the diagnostic approach as well as therapeutic options are discussed. © 2006 Wiley Periodicals, Inc. Head Neck, 2006 [source] Pancreatico-duodenectomy for complicated groove pancreatitisHPB, Issue 3 2007SAKHAWAT H. RAHMAN Objectives. Groove pancreatitis (GP) describes a form of segmental pancreatitis, which affects the pancreatic head at the interface with the duodenum, and is frequently associated with ectopic pancreatic tissue in the duodenal wall. We present a series of symptomatic patients with complicated GP who underwent pancreaticoduodenectomy, and review the diagnostic challenges, imaging modalities, pathological features and clinical outcome of this rare condition. Patients and methods. This was a prospective case base study of clinical, radiological and pathological data collected between the years 2000 and 2005 on patients diagnosed with severe GP , confirmed by histopathological examination following pancreaticoduodenectomy. Results. In total 11 patients were included, presenting with chronic abdominal pain (n= 11), gastric outlet obstruction (n= 5) and jaundice (n= 1). Exocrine dysfunction with associated weight loss (median > 9 kg) was present in 10 patients, and type 2 diabetes in 2 patients. Radiological imaging (CT/MRCP/EUS) provided complementary investigations and correlated well with classic histopathological findings (duodenal wall thickening, mucosal irregularity and Brunner's gland hyperplasia, duodenal wall cysts and pancreatic heterotropia). Following pancreaticoduodenectomy (median follow-up period 52 weeks) all patients experienced significant pain alleviation and weight gain (average 3 kg at 2 months). Conclusion. Pancreaticoduodenectomy is associated with significant improvements in weight gain and alleviates the chronic pain associated with severe GP. [source] Segmental testicular ischaemia: presentation, management and follow-upINTERNATIONAL JOURNAL OF ANDROLOGY, Issue 5 2009D. Gianfrilli Summary Segmental infarction of the testis is a rare event. Less than 40 cases have been reported in the literature and its aetiology remains largely unknown. The diagnosis is challenging and its identification crucial as partial ischaemia is frequently confused with testicular tumours and unnecessarily treated with orchiectomy. The objectives of this study are to: (i) raise awareness of this rare condition, (ii) provide the distinctive clinical and radiological features enabling pre-operative diagnosis, (iii) promote appropriate screening of causative factors and (iv) propose an alternative management approach to avoid surgery and preserve fertility. We describe three cases of partial testicular ischaemia in men presenting with reduced sperm quality. The cases demonstrate the ultrasound and magnetic resonance imaging appearance of testicular ischaemia. The surveillance strategy adopted for these lesions indicates that over 2 years of follow-up, marginal changes in the lesions can occur. Histology revealed that infiltration by stromal cells, leucocytes and macrophages is responsible for the remodelling of these lesions. Screening of risk factors for thromboembolism revealed that all patients carried a methylenetetrahydrofolate reductase 677C,T (MTHFR) mutation in a gene involved in folate metabolism, and either borderline or elevated homocysteine levels. Distinctive features permit the pre-operative diagnosis of segmental testicular ischaemia. There are sufficient data to assert that a surveillance strategy is safe and feasible. We speculate that the defects in folate metabolism may pre-dispose individuals to the development of testicular infarction and infertility. [source] Spontaneous rupture of non-parasitic hepatic cystINTERNATIONAL JOURNAL OF CLINICAL PRACTICE, Issue 1 2006G. Poggi Summary Intrahepatic cysts are generally classified as congenital, traumatic, infectious or neoplastic. Non-parasitic hepatic cysts (NPHCs) include simple cysts and adult polycystic liver disease in which the liver is diffusely occupied by cysts. NPHCs usually reach a large size before causing symptoms, unless a complication such as rupture, bleeding, infection, obstructive jaundice or neoplastic transformation occurs. We report the case of a 67-year-old man with spontaneous rupture of simple liver cyst. The clinical pictures and the unusual ultrasound features of this rare condition are discussed. [source] Xanthoma disseminatum in a black African womanINTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 11 2008FWACP, Shehu M. Yusuf MBBS Purpose, To report a partial steroid response of xanthoma disseminatum in a black African woman. Design, Case report and literature review. Methods, Histopathologic study of cutaneous tumour and clinical follow-up. Results, A 32-year-old black African woman with mucocutaneous xanthomatosis and dysphonia, which partially responded to treatment with steroids. Conclusions, Xanthoma dissseminatum is a rare condition for which there is no medical treatment. We reported the condition in a black African woman whose skin and CNS symptoms regressed remarkably within 22 weeks of steroid therapy. [source] Lupus erythematosus associated with erythema multiforme: Rowell's syndromeINTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 2007Nadia H. Shadid MD About 45 years ago, the association of lupus erythematosus with erythema multiforme and specific immunological laboratory changes was described for the first time. Since then, several patients with similar constellations of clinical symptoms and laboratory parameters have been reported. Today, this disease is known as Rowell's syndrome. However, the fact that not all patients described previously fit all clinical and immunological characteristics that had been originally reported raised the question if Rowell's syndrome really is an own entity or if the simultaneous occurrence of these clinical and immunological signs is rather incidental. Here, we describe a patient fulfilling most of the criteria of Rowell's syndrome and discuss what is currently known about this rare condition. [source] Multiple eccrine hidrocystomas of the faceINTERNATIONAL JOURNAL OF DERMATOLOGY, Issue 2 2001Abdullah Alfadley MD, FRCP(C) Background Multiple eccrine hidrocystomas of the face are a rare facial dermatosis for which no recent large series of cases has been reported. Objective To describe the clinicopathologic features of five cases of multiple eccrine hidrocystoma and to emphasize their similar characteristics. Methods The clinical and histologic features of five women with multiple eccrine hidrocystomas of the face are described. Results All cases were middle-aged women with numerous, asymptomatic, skin-colored to bluish, papulonodular skin lesions, ranging from 2 to 5 mm in diameter, and mainly centrifacial in distribution. Histopathologically, all cases showed unilocular cysts in the dermis lined by two layers of cuboidal cells. Staining for S-100 protein was negative in the cyst wall in all cases. One case was treated with topical 1% atropine for 3 weeks with no significant improvement. No systemic side-effects were observed during this treatment. Conclusions Multiple eccrine hidrocystomas are a rare condition which might be confused clinically and histopathologically with apocrine hidrocystomas. To date, no effective treatment has been reported. [source] Blocked D phenomenon, a rare condition with Rh D haemolytic disease of newborn , a case reportINTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, Issue 3 2008P. V. SULOCHANA Summary Accurate Rh testing can be difficult if the red cells are heavily coated with IgG anti D antibodies , a phenomenon called blocked D. Repeatedly, Rh D negative blood group report was obtained in a newborn male baby with severe haemolytic disease and features of kernicterus born to a 2nd gravida B Rh D negative mother. On investigation, the baby was grouped as B Rh D negative by direct grouping, but after elution, D antigen was detected and phenotyped as CcDe. Antibody was identified as anti D. All D antigens of the baby were fully saturated with anti D leaving any antigen to bind with antisera. Direct Coombs test was strongly positive even after three exchange transfusions. The baby also had free antibody apart from the red cell bound and the red cell eluate, gave a titre of 512. The mother was grouped as B Rh D negative and phenotyped as ce. She had IgM and IgG class of anti D with titres 32 and 1024 respectively. She also had IgM anti C (only in neat) and IgG anti-A with a titre of 512. [source] Polydactyly in the prehistoric American SouthwestINTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, Issue 3 2006D. T. Case Abstract General surveys of skeletal collections from Arizona for evidence of trauma and pathology led to the identification of polydactyly in two subadults. Polydactyly is a congenital condition characterised by the presence of extra digits on the hands or feet. Both affected subadults exhibit a sixth digit in the form of a branching fifth metatarsal. One of the affected individuals is an infant from the Tapia del Cerrito site exhibiting Y-shaped fifth metatarsals indicative of postaxial type A polydactyly. The second individual is a juvenile from the Nuvakwewtaqa (Chavez Pass Ruin) site exhibiting a left fifth metatarsal with a lateral branch, also diagnosed as postaxial type A polydactyly. These two cases appear to be the first examples of polydactyly from archaeological contexts identified among subadults, and bring the total number of known cases from the American Southwest to six. Discovery of so many examples of this relatively rare condition amongst the Puebloan people of the Southwest adds to the evidence that, rather than simply being an artistic motif, rock art depictions featuring hands and feet with six digits were probably inspired by observation of the condition amongst living people. Furthermore, burial treatment of the Tapia del Cerrito infant suggests that polydactyly may have conferred a special status on the bearer. Copyright © 2006 John Wiley & Sons, Ltd. [source] State of the art: Juvenile idiopathic arthritisINTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, Issue 1 2002Prudence J. Manners Abstract Juvenile idiopathic arthritis (JIA) is the most common of the autoimmune musculoskeletal conditions in children. As awareness of this condition increases, so too does the apparent prevalence reported from countries around the world, suggesting that significant numbers of children with JIA have previously gone undiagnosed. Prevalence varies with race and possibly geography. However, JIA should no longer be considered as a rare condition. In the past decade, there have been definite advances in understanding the pathogenesis of JIA, and there have been parallel advances in therapies. There have been fairly modest advances in the classification of JIA, but there is at least heightened international debate on the issue, which will lead to progress. It is estimated that nearly one-third of children with this condition continue into adult life with inflammatory joint disease, and therefore the burden of disease remains significant. [source] Clinical course linkage among different priapism subtypes: Dilemma in the management strategiesINTERNATIONAL JOURNAL OF UROLOGY, Issue 11 2008Shin-ichi Hisasue Objectives: Priapism is a rare condition whose management differs according to the etiology. We report the clinical course of three forms of priapism to assess the feasibility and safety of recent management strategies. Methods: The study included eight patients complaining of persistent erection for ,4 h who were treated in our institution between January 1996 and July 2007. Results: Overall, we categorized 12 cases of priapism in eight patients divided as follows: five cases of ischemic priapism (IP), three of stuttering priapism (SP), and four of non-ischemic priapism (NIP). Two of five IP patients needed a shunt procedure, which led to the subsequent erectile dysfunction. The other three were treated successfully with a corporal injection of sympathomimetic agents and subsequently suffered from SP. One of the three SP patients suffered from mimicked NIP with increased arterial blood flow during the initial treatment for IP. Four of the NIP patients including the mimicked one achieved complete detumescence, through arterial embolization in two and conservative management in two. Conclusions: Current management seems effective and safe in the short-term. However, the long-term outcome of the treatment for IP is still disappointing. Careful long-term observation is needed for an appropriate management. [source] Unusual case of post-cesarean vesicouterine fistula (Youssef's syndrome)INTERNATIONAL JOURNAL OF UROLOGY, Issue 4 2003FERHAT KILINC Abstract Vesicouterine fistula without vaginal leakage of urine, cyclic hematuria and amenorrhea is a rare condition, referred to as Youssef's syndrome. The most common cause of this syndrome is trauma during a cesarean section. Herein a new case is reported. [source] Case of mediastinal seminoma with testicular microlithiasisINTERNATIONAL JOURNAL OF UROLOGY, Issue 2 2002Koji Sato Abstract Testicular microlithiasis is a rare condition in which calcified concretions fill the lumina of the seminiferous tubules. We report the case of a 19-year-old Japanese man with mediastinal seminoma, normal testicular physical findings and bilateral testicular microlithiasis seen on ultrasonography. Testicular needle biopsy demonstrated multiple laminated calcifications within the seminiferous tubules without any signals of a viable germ cell tumor. To our knowledge, this is only the sixth reported case of extragonadal germ cell tumor with testicular microlithiasis. [source] Gorham-Stout Disease,Stabilization During Bisphosphonate Treatment,JOURNAL OF BONE AND MINERAL RESEARCH, Issue 2 2005Fabian Hammer Abstract A 45-year-old woman presented with recent onset of left-sided chest pain. On clinical examination, these symptoms seemed to be strictly localized to a region that was marked by a long-standing cutaneous erythematous lesion. Laboratory results showed no gross abnormalities. Radiological imaging including conventional X-ray, MRI scans, and 3D CT reconstruction of the rib cage revealed circumscript destruction of the left lateral ribs 9,11. Histological analysis of a rib biopsy showed angiomatous hypervascularization and intracortical fibrosis. In keeping with these findings, the patient's condition was diagnosed as Gorham-Stout disease, a rare condition with localized, often unilateral, bone destruction. Monotherapy with bisphosphonates (pamidronate 30 mg IV every 3 months) was initiated, leading to rapid disappearance of local pain. Follow-up over 24 months documented a stable clinical and radiological picture without evidence of progressive bone destruction. [source] Palatal radicular multigrooves associated with severe periodontal defects in maxillary central incisorsJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 4 2001Koichi Nanba Abstract Background: This case report describes a rare condition of palatal radicular multigrooves on teeth 11 and 21 with severe periodontal defects and the findings at 3-year follow-up. Method: Radiculoplasty using hand curettes and rotary burs were used to remove the multigrooves on the root surfaces and change the wrinkled root form to the relatively flat and smooth normal root morphology. Minor tooth movement and frenotomy were performed for a diastema between teeth 11 and 21. Supportive periodontal therapy started immediately after completion of the active treatment. Results: Improved healthy periodontal tissues and adequate plaque control have been maintained. Zusammenfassung Dieser Fallbericht beschreibt das seltene Phänomen multipler palatinaler Wurzelfurchen an den Zähnen 11 und 21 bei einer 41-jährigen Japanerin in Assoziation mit schweren parodontalen Defekten und berichtet die Beobachtungen einer Verlaufskontrolle über 3 Jahre. Die Furchen wurden im Sinne einer Odontoplastik mit Handküretten und rotierenden Instrumenten entfernt und so die zerklüftete Wurzeloberfläche in eine glatte normale Wurzelmorphologie überführt. Geringfügige Zahnbewegungen und eine Frenektomie wurden zur Behandlung des Diastemas durchgeführt. Unmittelbar nach Abschluß der aktiven Therapie wurde die unterstützende Nachsorge begonnen. Ein verbesserter parodontaler Zustand und adäquate Plaquekontrolle haben seither aufrechterhalten werden können. Résumé Ce rapport de cas montre une rare présence de sillons radiculaires palatins multiples sur les dent 11 et 21 avec des lésions parodontales sévères et les résultats sur un suivi de 3 ans. Une radiculoplastie fut réalisée à l'aide de curettes à mains et de fraises rotatives pour éliminer les sillons radiculaires multiples et modifier la forme plissée de la racine en une morphologie radiculaire plate et lisse relativement normale. Des mouvements dentaires mineurs et une frénotomie ont été réalisés à cause d'un diastème entre 11 et 21. Le traitement parodontal de soutien a commencé immédiatement après l'achèvement du traitement actif. Des tissus parodontaux sains améliorés et un contrôle de plaque adéquat ont été maintenus. [source] | ||||||||||||||||||||||||||||||||||||||||||||||