Questions Relevant (question + relevant)

Distribution by Scientific Domains


Selected Abstracts


Testing for cannabis in the work-place: a review of the evidence

ADDICTION, Issue 3 2010
Scott Macdonald
ABSTRACT Background Urinalysis testing in the work-place has been adopted widely by employers in the United States to deter employee drug use and promote ,drug-free' work-places. In other countries, such as Canada, testing is focused more narrowly on identifying employees whose drug use puts the safety of others at risk. Aims We review 20 years of published literature on questions relevant to the objectives of work-place drug testing (WPDT), with a special emphasis on cannabis, the most commonly detected drug. Results We conclude (i) that the acute effects of smoking cannabis impair performance for a period of about 4 hours; (ii) long-term heavy use of cannabis can impair cognitive ability, but it is not clear that heavy cannabis users represent a meaningful job safety risk unless using before work or on the job; (iii) urine tests have poor validity and low sensitivity to detect employees who represent a safety risk; (iv) drug testing is related to reductions in the prevalence of cannabis positive tests among employees, but this might not translate into fewer cannabis users; and (v) urinalysis has not been shown to have a meaningful impact on job injury/accident rates. Conclusions Urinalysis testing is not recommended as a diagnostic tool to identify employees who represent a job safety risk from cannabis use. Blood testing for active tetrahydrocannabinol (THC) can be considered by employers who wish to identify employees whose performance may be impaired by their cannabis use. [source]


Not in Anyone's Backyard: The Emergence and Identity of a Transnational Anti-Base Network

INTERNATIONAL STUDIES QUARTERLY, Issue 3 2009
Andrew Yeo
Providing an overview of the emergence, characteristics, trajectory, and potential limitations of the transnational anti-base network, this article focuses on two broad questions relevant to transnational politics. First, what processes and mechanisms enabled local and transnational activists to form the international No Bases network? Second, how did activists juxtapose existing local anti-base identity and frames to emerging transnational ones? Following existing transnational movement theories, I argue that the global anti-base network slowly emerged through processes of diffusion and scale shift in its early stages. The onset of the Iraq War, however, injected new life into the transnational anti-base movement, eventually leading to the inaugural International Conference for the Abolition of Foreign Bases in 2007. Although loose transnational ties existed among anti-base activists prior to 2003, the U.S. war in Iraq presented anti-base activists the global frames necessary to accelerate the pace of diffusion, scale-shift, and brokerage, and hence, the consolidation of a transnational anti-base network. Paradoxically, however, even as No Bases leaders attempted to forge a new transnational identity, anti-base activists, as "rooted cosmopolitans," continued to anchor their struggle in local initiatives. [source]


Economic determinants of biodiversity change over a 400-year period in the Scottish uplands

JOURNAL OF APPLIED ECOLOGY, Issue 6 2008
Nick Hanley
Summary 1Economic forces are recognized as an important driving factor behind current biodiversity losses. This study investigates whether such factors have been important in determining one measure of biodiversity change over the ,long run', in our case, 400 years , for upland sites in Scotland. 2A combination of palaeoecological, historical and economic methods is used to construct and then analyse a database of factors contributing to changes in plant diversity over time for 11 upland sites. 3Using an instrumental variables panel model, we find livestock prices, our proxy for grazing pressure, to be a statistically significant determinant of diversity change, with higher grazing pressures resulting in lower diversity values on average, although site abandonment is also found to result in a fall in plant diversity. Technological change, such as the introduction of new animal breeds, was not found to be a statistically significant determinant. 4Using later period data (post 1860) on livestock numbers at the parish (local) level, we were able to confirm the main result noted above (3) in terms of the effects of higher grazing pressures on plant diversity. 5Synthesis and applications. This study shows how data from very different disciplines can be combined to address questions relevant to contemporary conservation and understanding. This novel, interdisciplinary approach provides new insights into the role of economic factors as a driver of biodiversity loss in the uplands. Biodiversity levels have varied considerably over 400 years, partly as a function of land management, suggesting that establishing baselines or ,natural' target levels for biodiversity is likely to be problematic. Changes in livestock grazing pressures brought about by changes in prices had statistically significant effects on estimated plant diversity, as did land abandonment. This suggests that long-term management of upland areas for the conservation of diversity should focus on grazing pressures as a key policy attribute. Another policy implication is that drastic cuts in grazing pressures , such as might occur under current reforms of the Common Agricultural Policy , can have adverse biodiversity consequences. [source]


Development of Luteinizing Hormone Releasing Hormone Neurones

JOURNAL OF NEUROENDOCRINOLOGY, Issue 1 2001
S. Wray
Abstract This review concentrates on some of the recent discoveries and future questions relevant to the development of the neuroendocrine luteinizing hormone releasing hormone (LHRH) cells. Neuroendocrine LHRH cells originate outside the central nervous system, in the nasal placode, and thereafter migrate into the forebrain during prenatal development. It is this population of LHRH cells that is responsible for reproductive function, becoming integral members of the hypothalamo-pituitary-gonadal axis postnatally. Disruption of the development of this system results in reproductive dysfunction. Increasing our understanding of LHRH neuroendocrine cells establishes conditions where we can look with greater precision at the mechanisms controlling reproductive development, both activation and failure. In addition, the ability to manipulate the molecular and cellular biology of the LHRH system opens the route to understanding critical neurobiological issues such as phenotypic commitment, axonal path finding and mechanisms involved in neuronal migration. Each of the topics is discussed in turn and potential mechanisms controlling the development of the neuroendocrine LHRH system are indicated. [source]


Implants and/or teeth: consensus statements and recommendations

JOURNAL OF ORAL REHABILITATION, Issue 2008
K. GOTFREDSEN
Summary, In August 23,25, 2007, the Scandinavian Society for Prosthetic Dentistry in collaboration with the Danish Society of Oral Implantology arranged a consensus conference on the topic ,Implants and/or teeth'. It was preceded by a workshop in which eight focused questions were raised and answered in eight review articles using a systematic approach. Twenty-eight academicians and clinicians discussed the eight review papers with the purpose to reach consensus on questions relevant for the topic. At the conference the consensus statements were presented as well as lectures based on the review articles. In this article the methods used at the consensus workshop are briefly described followed by the statements with comments. [source]


Editor's Introduction , Autonomy of Inquiry: Shaping the Future of Emerging Scientific Communities

MANAGEMENT AND ORGANIZATION REVIEW, Issue 1 2009
Anne S. Tsui
abstract Over two decades, research in Chinese management has exploited existing questions, theories, constructs, and methods developed in the Western context. Lagging are exploratory studies to address questions relevant to Chinese firms and to develop theories that offer meaningful explanations of Chinese phenomena. Framed as a debate between pursuing a theory of Chinese management versus a Chinese theory of management, this forum, through the voices of thirteen scholars, provides an analysis of the reasons for the current status of Chinese management research and offers alternatives to shape the future of Chinese management studies. Based on the principle of autonomy of inquiry and heeding the warning of the constraint of normal science, the Chinese management research community can shape its own future by engaging in research that may contribute to global management knowledge and address meaningful local management problems. [source]


Customization: Impact on Product and Process Performance

PRODUCTION AND OPERATIONS MANAGEMENT, Issue 4 2005
Vishwanath G. Hegde
Manufacturing capability has often been viewed to be a major obstacle in achieving higher levels of customization. Companies follow various strategies ranging from equipment selection to order process management to cope with the challenges of increased customization. We examined how the customization process affects product performance and conformance in the context of a design-to-order (DTO) manufacturer of industrial components. Our competing risk hazard function model incorporates two thresholds, which we define as mismatch and manufacturing thresholds. Product performance was adversely affected when the degree of customization exceeded the mismatch threshold. Likewise, product conformance eroded when the degree of customization exceeded the manufacturing threshold. Relative sizes of the two thresholds have management implications for the subsequent investments to improve customization capabilities. Our research developed a rigorous framework to address two key questions relevant to the implementation of product customization: (1) what degrees of customization to offer, and (2) how to customize the product design process. [source]


Evidence-based Reviews and Databases: Are They Worth the Effort?

ACADEMIC EMERGENCY MEDICINE, Issue 11 2007
Developing Evidence Summaries for Emergency Medicine
A broad range of relevant evidence-based resources within and outside of emergency medicine (EM) collates and summarizes research evidence pertaining to many questions relevant to clinical emergency care. Such resources may or may not constitute the equivalent of health care recommendations, and their relationship to clinical decision-making may be complex. Many efforts in evidence-based medicine resource development, and their products, are marginally relevant to EM practice but may serve as useful models for parallel EM relevant efforts. A trade-off exists between synthesis quality and ease of practitioner access and use. Keeping all such resources up to date is a major challenge. Although observational evidence suggests that dynamic interactivity and information retrieval technology may enhance practitioner utilization, little evidence exists supporting the absolute or comparative effectiveness of different kinds of resources and databases in enhancing evidence uptake or changing clinician behavior. [source]