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Quantitative Perspective (quantitative + perspective)
Selected AbstractsUse of evaporative light scattering detector in the detection and quantification of enantiomeric mixtures by HPLCJOURNAL OF SEPARATION SCIENCE, JSS, Issue 10 2006Tong Zhang Abstract Routinely used in our laboratories at analytical scale, an evaporative light scattering detector (ELSD) has proved to be versatile in the detection of enantiomeric resolution using chiral stationary phases by HPLC. Though this kind of detector has been widely used in various domains, its application in enantiomeric resolution has not been discussed in the literature and is found to have very specific features especially in the quantitative perspective. In contrast with the UV detection, the peak area from ELSD for both enantiomers of a racemic mixture may not be the same. This complicates the assessment of the enantiomeric purity of unknown samples. This current work deals with some practical aspects in the detection of enantiomers and in accurate quantitative determination of enantiomeric purity by ELSD. Effects of analyte nature (more precisely molecular weight and volatility), peak shape and peak shape difference between enantiomers on the quantitative integration by ELSD are discussed in connection with the UV-detection results. The calibration for quantitative enantiomeric analysis and its effectiveness are demonstrated. [source] Transplantation Risks and the Real World: What Does ,High Risk' Really Mean?AMERICAN JOURNAL OF TRANSPLANTATION, Issue 1 2009R. B. Freeman Candidates for, and recipients of, transplants face numerous risks that receive varying degrees of attention from the media and transplant professionals. Characterizations such as ,high risk donor' are not necessarily accurate or informative unless they are discussed in context with the other risks patients face before and after transplantation. Moreover, such labels do not provide accurate information for informed consent discussions or decision making. Recent cases of donor-transmitted diseases from donors labeled as being at ,high risk' have engendered concern, new policy proposals and attempts to employ additional testing of donors. The publicity and policy reactions to these cases do not necessarily better inform transplant candidates and recipients about these risks. Using comparative risk analysis, we compare the various risks associated with waiting on the list, accepting donors with various risk characteristics, posttransplant survival and everyday risks we all face in modern life to provide some quantitative perspective on what ,high risk' really means for transplant patients. In our analysis, donor-transmitted disease risks are orders of magnitude less than other transplantation risks and similar to many everyday occupational and recreational risks people readily and willingly accept. These comparisons can be helpful for informing patients and guiding future policy development. [source] Are Specific and Generalized Social Phobias Qualitatively Distinct?CLINICAL PSYCHOLOGY: SCIENCE AND PRACTICE, Issue 4 2002Julie N. Hook This article reviews studies of the generalized (CSP) and specific (SSP) subtypes of social phobia, including their onset, course, etiology, comorbid conditions, types of situations feared, reactions (i.e., cognitive, physiological, and behavioral) to feared situations, and response to treatment. Because the differences between CSP and SSP seem difficult to reconcile with a strictly quantitative perspective, we propose a qualitative distinction. The characteristics of SSP are seen as similar to those of specific phobias, but those of CSP are not. We offer a speculative interpersonal model of CSP that emphasizes beliefs about the self being unlovable, behaviors that elicit negative self-evaluations in others, and a pattern of mutual social-distancing behaviors. We discuss the implications of a qualitative distinction between CSP and SSP and offer avenues for future inquiry. [source] Children speak about neighborhoods: using mixed methods to measure the construct neighborhoodJOURNAL OF COMMUNITY PSYCHOLOGY, Issue 3 2008Nicole NicoteraArticle first published online: 18 MAR 200 This study contributes to the knowledge base of community practice and research by examining the construct neighborhood from qualitative and quantitative perspectives. Mixed methodology was employed to explore the associations and discrepancies between a census measure of neighborhood based in social disorganization theory and a qualitative measure based on the voices of children (N=59). Qualitative results indicate nine dimensions of the construct neighborhood that are not found in census-based measures of the construct. Mixed methods results demonstrate that children in both higher and lower socially disorganized neighborhoods express the presence of neighborhood resources and neighborly affiliations as well as negative neighborhood experiences. Expressions of fear, needs for safety, and qualities of unsavory characters distinguish the two types of neighborhoods. © 2008 Wiley Periodicals, Inc. [source] | ||||||||||