Home About us Contact
|
Home About us Contact | ||
|
|
||
Published Examples (published + example)
Selected AbstractsImproved imaging with phase-weighted common conversion point stacks of receiver functionsGEOPHYSICAL JOURNAL INTERNATIONAL, Issue 1 2010A. Frassetto SUMMARY Broad-band array studies frequently stack receiver functions to improve their signal-to-noise ratio while mapping structures in the crust and upper mantle. Noise may produce spurious secondary arrivals that obscure or mimic arrivals produced by P -to- S conversions at large contrasts in seismic impedance such as the Moho. We use a Hilbert transform to calculate phase-weights, which minimize the constructive stacking of erroneous signal in receiver function data sets. We outline this approach and demonstrate its application through synthetic data combined with different types of noise, a previously published example of signal-generated noise, and a large data set from the Sierra Nevada EarthScope Project. These examples show that phase-weighting reduces the presence of signal-generated noise in receiver functions and improves stacked data sets. [source] A case study of os cuneiforme mediale bipartum from Sigtuna, SwedenINTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, Issue 6 2004A. KjellströmArticle first published online: 16 NOV 200 Abstract An adult male from an early Medieval mass grave in Sigtuna displayed bilateral os cuneiforme mediale bipartum. This is an unusual congenital anomaly and this study is the first published example found in an archaeological skeletal assemblage in Sweden. Another adult male in the same grave shows horizontal grooves of both medial cuneiform bones. This paper discusses a possible hereditary tendency of the anomalies. Copyright © 2004 John Wiley & Sons, Ltd. [source] Ranking indirect connections in literature-based discovery: The role of medical subject headingsJOURNAL OF THE AMERICAN SOCIETY FOR INFORMATION SCIENCE AND TECHNOLOGY, Issue 11 2006Don R. Swanson Arrowsmith, a computer-assisted process for literature-based discovery, takes as input two disjoint sets of records (A, C) from the Medline database. It produces a list of title words and phrases, B, that are common to A and C, and displays the title context in which each B-term occurs within A and within C. Subject experts then can try to find A,B and B,C title-pairs that together may suggest novel and plausible indirect A,C relationships (via B-terms) that are of particular interest in the absence of any known direct A,C relationship. The list of B-terms typically is so large that it is difficult to find the relatively few that contribute to scientifically interesting connections. The purpose of the present article is to propose and test several techniques for improving the quality of the B-list. These techniques exploit the Medical Subject Headings (MeSH) that are assigned to each input record. A MesH-based concept of literature cohesiveness is defined and plays a key role. The proposed techniques are tested on a published example of indirect connections between migraine and magnesium deficiency. The tests demonstrate how the earlier results can be replicated with a more efficient and more systematic computer-aided process. [source] Reproductive health services for refugees by refugees: an example from GuineaDISASTERS, Issue 1 2010Anna Von Roenne The need to involve refugees in their own reproductive health (RH) services has long been recognised, but there is a lack of published examples describing how this can be achieved collaboratively between refugee initiatives, UNHCR, bilateral development organisations and international relief agencies. This paper outlines the work, outputs and lessons learnt of the Reproductive Health Group (RHG), an organisation of Liberian and Sierra Leonean refugee midwives and laywomen providing RH services to fellow refugees in Guinea's Forest Region between 1996 and 2000. Working as part of the Guinean health system, RHG midwives and community facilitators helped make the RH services in their region the most effective in Guinea at the time. Looking at RHG's achievements, the challenges it faced and partly overcame, it is argued that refugee organisations can plan and implement RH services for refugees where UNHCR and its international partners ensure that they receive funding and technical assistance. [source] 3D resistivity inversion using 2D measurements of the electric fieldGEOPHYSICAL PROSPECTING, Issue 1 2001P.D. Jackson Field and ,noisy' synthetic measurements of electric-field components have been inverted into 3D resistivities by smoothness-constrained inversion. Values of electrical field can incorporate changes in polarity of the measured potential differences seen when 2D electrode arrays are used with heterogeneous ,geology', without utilizing negative apparent resistivities or singular geometrical factors. Using both the X - and Y -components of the electric field as measurements resulted in faster convergence of the smoothness-constrained inversion compared with using one component alone. Geological structure and resistivity were reconstructed as well as, or better than, comparable published examples based on traditional measurement types. A 2D electrode grid (20 × 10), incorporating 12 current-source electrodes, was used for both the practical and numerical experiments; this resulted in 366 measurements being made for each current-electrode configuration. Consequently, when using this array for practical field surveys, 366 measurements could be acquired simultaneously, making the upper limit on the speed of acquisition an order of magnitude faster than a comparable conventional pole,dipole survey. Other practical advantages accrue from the closely spaced potential dipoles being insensitive to common-mode noise (e.g. telluric) and only 7% of the electrodes (i.e. those used as current sources) being susceptible to recently reported electrode charge-up effects. [source] Selective sampling for approximate clustering of very large data setsINTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS, Issue 3 2008Liang Wang A key challenge in pattern recognition is how to scale the computational efficiency of clustering algorithms on large data sets. The extension of non-Euclidean relational fuzzy c-means (NERF) clustering to very large (VL = unloadable) relational data is called the extended NERF (eNERF) clustering algorithm, which comprises four phases: (i) finding distinguished features that monitor progressive sampling; (ii) progressively sampling from a N × N relational matrix RN to obtain a n × n sample matrix Rn; (iii) clustering Rn with literal NERF; and (iv) extending the clusters in Rn to the remainder of the relational data. Previously published examples on several fairly small data sets suggest that eNERF is feasible for truly large data sets. However, it seems that phases (i) and (ii), i.e., finding Rn, are not very practical because the sample size n often turns out to be roughly 50% of n, and this over-sampling defeats the whole purpose of eNERF. In this paper, we examine the performance of the sampling scheme of eNERF with respect to different parameters. We propose a modified sampling scheme for use with eNERF that combines simple random sampling with (parts of) the sampling procedures used by eNERF and a related algorithm sVAT (scalable visual assessment of clustering tendency). We demonstrate that our modified sampling scheme can eliminate over-sampling of the original progressive sampling scheme, thus enabling the processing of truly VL data. Numerical experiments on a distance matrix of a set of 3,000,000 vectors drawn from a mixture of 5 bivariate normal distributions demonstrate the feasibility and effectiveness of the proposed sampling method. We also find that actually running eNERF on a data set of this size is very costly in terms of computation time. Thus, our results demonstrate that further modification of eNERF, especially the extension stage, will be needed before it is truly practical for VL data. © 2008 Wiley Periodicals, Inc. [source] Breaking symmetry in protein dimers: Designs and functionsPROTEIN SCIENCE, Issue 1 2006Jerry H. Brown Abstract Symmetry, and in particular point group symmetry, is generally the rule for the global arrangement between subunits in homodimeric and other oligomeric proteins. The structures of fragments of tropomyosin and bovine fibrinogen are recently published examples, however, of asymmetric interactions between chemically identical chains. Their departures from strict twofold symmetry are based on simple and generalizable chemical designs, but were not anticipated prior to their structure determinations. The current review aims to improve our understanding of the structural principles and functional consequences of asymmetric interactions in proteins. Here, a survey of >100 diverse homodimers has focused on the structures immediately adjacent to the twofold axis. Five regular frameworks in ,-helical coiled coils and antiparallel ,-sheets accommodate many of the twofold symmetric axes. On the basis of these frameworks, certain sequence motifs can break symmetry in geometrically defined manners. In antiparallel ,-sheets, these asymmetries include register slips between strands of repeating residues and the adoption of different side-chain rotamers to avoid steric clashes of bulky residues. In parallel coiled coils, an axial stagger between the ,-helices is produced by clusters of core alanines. Such simple designs lead to a basic understanding of the functions of diverse proteins. These functions include regulation of muscle contraction by tropomyosin, blood clot formation by fibrin, half-of-site reactivity of caspase-9, and adaptive protein recognition in the matrix metalloproteinase MMP9. Moreover, asymmetry between chemically identical subunits, by producing multiple equally stable conformations, leads to unique dynamic and self-assembly properties. [source] Conceptual bases for quantifying the role of the environment on gene evolution: the participation of positive selection and neutral evolutionBIOLOGICAL REVIEWS, Issue 4 2007Anthony Levasseur Abstract To demonstrate that a given change in the environment has contributed to the emergence of a given genotypic and phenotypic shift during the course of evolution, one should ask to what extent such shifts would have occurred without environmental change. Of course, such tests are rarely practical but phenotypic novelties can still be correlated to genomic shifts in response to environmental changes if enough information is available. We surveyed and re-evaluated the published data in order to estimate the role of environmental changes on the course of species and genomic evolution. Only a few published examples clearly demonstrate a causal link between a given environmental change and the fixation of a genomic variant resulting in functional modification (gain, loss or alteration of function). Many others suggested a link between a given phenotypic shift and a given environmental change but failed to identify the underlying genomic determinant(s) and/or the associated functional consequence(s). The proportion of genotypic and phenotypic variation that is fixed concomitantly with environmental changes is often considered adaptive and hence, the result of positive selection, even though alternative causes, such as genetic drift, are rarely investigated. Therefore, the second aim herein is to review evidence for the mechanisms leading to fixation. [source] | |||||||||||||