Home About us Contact | |||
PSS Scores (pss + score)
Selected AbstractsDisease control, survival, and functional outcome after multimodal treatment for advanced-stage tongue base cancerHEAD & NECK: JOURNAL FOR THE SCIENCES & SPECIALTIES OF THE HEAD AND NECK, Issue 7 2004James P. Malone MD Abstract Background. Surgical resection and postoperative radiation for advanced-stage malignancies of the oral cavity, oropharynx, and hypopharynx result in a dismal overall survival of 38%. Patients with carcinoma of the tongue base frequently have advanced disease at the time of presentation, and combined-modality therapy is usually required to achieve cure. Because of the poor survival rates with advanced malignancies with standard therapy, new and innovative approaches continue to be developed in an attempt to have a greater impact on disease control, patient survival, and functional outcome after therapy. This study examines functional outcome, survival, and disease control in patients receiving an intensified treatment regimen with concomitant chemoradiotherapy, surgery, and intraoperative radiotherapy for previously untreated, resectable, stage III and IV squamous cell carcinoma (SCC) of the tongue base. Methods. Forty patients with previously untreated, resectable, stage III and IV squamous cell carcinoma of the tongue base were treated in one of three sequential phase II intensification regimens (IRs). Treatment consisted of perioperative, hyperfractionated radiotherapy (9.1 Gy) with concurrent cisplatin followed by surgical resection with intraoperative radiotherapy boost (7.5 Gy). Postoperative treatment involved concurrent chemoradiotherapy (40 Gy to the primary site and upper neck and 45 Gy to the supraclavicular areas) with cisplatin with or without paclitaxel. Locoregional and distant disease control, 2-year overall, and disease-specific survival rates were calculated. The Performance Status Scale (PSS) for Head and Neck Cancer Patients was administered to 25 of the surviving patients. The effects of the method of surgical reconstruction, surgery involving the mandible and/or larynx, and early versus advanced T stage on PSS score were evaluated with the Wilcoxon rank-sum test. Results. Median follow-up in months for IR1, IR2, and IR3 were 83.6, 75.2, and 26.8. The locoregional control rate was 100%, and the rate of distant metastases was 7.5% for all patients. Two-year overall and disease-specific survival rates for the entire study population were 74.7% and 93.6%, respectively. Mean PSS scores by subscales Eating in Public, Understandability of Speech, and Normalcy of Diet were 55 (range, 0,100), 73 (range, 25,100), and 49 (range, 0,100), respectively. PSS scores were significantly higher in patients with primary closure of the surgical defect, no mandibular surgery, and early T-stage lesions. Conclusions. Although functional outcome may be decreased by certain surgical interventions and advanced T stage, the high rate of locoregional and distant disease control and excellent 2-year disease-specific survival supports an aggressive treatment regimen for advanced tongue base cancer. © 2004 Wiley Periodicals, Inc. Head Neck26: 561,572, 2004 [source] The relationship of sleep quality and posttraumatic stress to potential sleep disorders in sexual assault survivors with nightmares, insomnia, and PTSDJOURNAL OF TRAUMATIC STRESS, Issue 4 2001Barry Krakow Abstract Sleep quality and posttraumatic stress disorder (PTSD) were examined in 151 sexual assault survivors, 77% of whom had previously reported symptoms of sleep-disordered breathing (SDB) or sleep movement disorders (SMD) or both. Participants completed the Pittsburgh Sleep Quality Index (PSQI) and the Posttraumatic Stress Scale (PSS). High PSQI scores reflected extremely poor sleep quality and correlated with PSS scores. PSQI scores were greater in participants with potential SDB or SMD or both. PSQI or PSS scores coupled with body-mass index and use of antidepressants or anxiolytics predicted potential sleep disorders. The relationship between sleep and posttraumatic stress appears to be more complex than can be explained by the current PTSD paradigm; and, sleep breathing and sleep movement disorders may be associated with this complexity. [source] An Exploration of the Relationship Between Depressive Symptoms and Cortisol Rhythms in Colorado RanchersTHE JOURNAL OF RURAL HEALTH, Issue 1 2009Emily Schulze MA ABSTRACT:,Context: Although the effects of stress on health have been studied in numerous urban-dwelling populations, fewer studies have addressed these effects in rural populations, such as farmers and ranchers. Purpose: The present study focuses on seasonal levels of depressed affect and perceived stress in Western Colorado ranchers, and how those phenomena related to their levels of cortisol. Methods: Twenty-one (21) ranchers, who were permittees on the Colorado Grand Mesa, completed the study. Participants identified 2-week time periods during the year representing relative high, medium, and low stress. During each period, participants took saliva samples, rated stress levels, and completed a daily health diary. In addition, the Beck Depression Inventory (BDI-II), the perceived stress scale (PSS), and a life events scale (LES) were administered. Results: Results showed a strong relationship between BDI-II and PSS scores (r = 0.748, P < .01). The decreased daytime cortisol decline supports the notion that the hypothalamic-pituitary-adrenal (HPA) axis negative feedback loop is disrupted in chronic stress and depression, thus resulting in chronically elevated cortisol levels. Conclusion: This study supports the relationship between stress, depression, and HPA dysregulation in ranchers. [source] The health of children in sole-parent families in New Zealand: results of a population-based cross-sectional surveyAUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, Issue 3 2010Martin Tobias Abstract Objective: To investigate whether children in sole-parent families in New Zealand bear excess risks of poor mental and physical health relative to children in two parent families. Data sources and statistical methods: The data source was the 2006/07 New Zealand Health Survey, a nationally representative household survey that sampled 502 children (5-14 years) of sole mothers and 1,281 children of partnered mothers. Results: Children of sole mothers were 1.26 (0.94 , 2.69) times as likely as children of partnered mothers to return a low PhS score. Adjusting for maternal health and family socio-economic disadvantage eliminated this weak association (which in any case was of borderline statistical significance). Children of sole mothers were more than twice as likely as children of partnered mothers to return a low PsS score, adjusting for demographic variables only. Conclusions: There is only a weak negative association (if any) between sole-parenting and child physical health, but a stronger association with child mental health , consistent with most of the New Zealand and international literature. The association with child mental health is largely (but possibly not completely) ,explained' by the poorer mental health of sole-parents and the poorer socio-economic circumstances of single-parent families (on average). Implications: These findings support policies aiming to improve access of sole-parents and their children to community mental health services, and (more especially) policies aiming to ameliorate the disadvantaged economic circumstances of single parent families. [source] |