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Project Initiatives (project + initiative)
Selected AbstractsChemical Biology and Drug Design: World Project InitiativeCHEMICAL BIOLOGY & DRUG DESIGN, Issue 3 2006Tomi K. Sawyer No abstract is available for this article. [source] Reflections on training in child abuse and neglect prevention: Experiences in BrazilCHILD ABUSE REVIEW, Issue 6 2007Victoria Gabrielle Lidchi Abstract In cooperation with an international partner, Brazilian professionals based in Rio de Janeiro designed a training programme in child protection to respond to the particular challenges to effective practice posed by the local environment and to address obstacles to its achievement in the existing child protection system. Training participants used a structured process to identify and address such external challenges and internal obstacles. The use of the framework included an exploration of beliefs held by Brazilian child protection professionals. The training was itself envisaged as an intervention opportunity for participants to promote ,bottom up' processes of local systemic change. The programme aimed to provide training that accessed the experience of the international partner's ,community of expertise', but mitigated the risk to effectiveness of a ,transplant' programme that fails to engage with the surrounding social reality and culture. As part of a nine-country international training project initiative (ITPI, International Training Project Initiative by ISPCAN) sponsored by the International Society for the Prevention of Child Abuse and Neglect (ISPCAN), standardised tools were adopted to monitor and evaluate the training process. Copyright © 2007 John Wiley & Sons, Ltd. [source] Identifying Rarer Genetic Variants for Common Complex Diseases: Diseased Versus Neutral Discovery PanelsANNALS OF HUMAN GENETICS, Issue 1 2009K. Curtin Summary The power of genetic association studies to identify disease susceptibility alleles fundamentally relies on the variants studied. The standard approach is to determine a set of tagging-SNPs (tSNPs) that capture the majority of genomic variation in regions of interest by exploiting local correlation structures. Typically, tSNPs are selected from neutral discovery panels - collections of individuals comprehensively genotyped across a region. We investigated the implications of discovery panel design on tSNP performance in association studies using realistically-simulated sequence data. We found that discovery panels of 24 sequenced ,neutral' individuals (similar to NIEHS or HapMap ENCODE data) were sufficient to select well-powered tSNPs to identify common susceptibility alleles. For less common alleles (0.01,0.05 frequency) we found neutral panels of this size inadequate, particularly if low-frequency variants were removed prior to tSNP selection; superior tSNPs were found using panels of diseased individuals. Only large neutral panels (200 individuals) matched diseased panel performance in selecting well-powered tSNPs to detect both common and rarer alleles. The 1000 Genomes Project initiative may provide larger neutral panels necessary to identify rarer susceptibility alleles in association studies. In the interim, our results suggest investigators can boost power to detect such alleles by sequencing diseased individuals for tSNP selection. [source] Reflections on training in child abuse and neglect prevention: Experiences in BrazilCHILD ABUSE REVIEW, Issue 6 2007Victoria Gabrielle Lidchi Abstract In cooperation with an international partner, Brazilian professionals based in Rio de Janeiro designed a training programme in child protection to respond to the particular challenges to effective practice posed by the local environment and to address obstacles to its achievement in the existing child protection system. Training participants used a structured process to identify and address such external challenges and internal obstacles. The use of the framework included an exploration of beliefs held by Brazilian child protection professionals. The training was itself envisaged as an intervention opportunity for participants to promote ,bottom up' processes of local systemic change. The programme aimed to provide training that accessed the experience of the international partner's ,community of expertise', but mitigated the risk to effectiveness of a ,transplant' programme that fails to engage with the surrounding social reality and culture. As part of a nine-country international training project initiative (ITPI, International Training Project Initiative by ISPCAN) sponsored by the International Society for the Prevention of Child Abuse and Neglect (ISPCAN), standardised tools were adopted to monitor and evaluate the training process. Copyright © 2007 John Wiley & Sons, Ltd. [source] World Bank Influence and Institutional Reform in ArgentinaDEVELOPMENT AND CHANGE, Issue 3 2009Maria F. Tuozzo ABSTRACT During the 1990s, reforms concerned with ,good governance' became popular with multilateral and bilateral lenders. This trend was led by the World Bank, which claimed that in order to achieve economic development, institutions mattered. This article looks at governance reforms in Argentina, specifically in the judicial sector, and contends that World Bank involvement affected the nature, reach and depth of these initiatives. The influence of the Bank can be traced through three dimensions that have characterized its approach to institutional reform: donor-driven designs for project reform; reliance on technical approaches; and restricted forms of decision making in project initiatives. Such an approach to institutional change conditioned domestic reform in Argentina and contributed to piecemeal and inadequate initiatives. The author also argues that the Bank's approach in Argentina can be traced to wider strategies that derive from embedded institutional practices and ideological foundations within the institution that throw into question the Bank's capacities to promote such reforms. [source] Project Development in Complex Environments: Assessing Safety in Design and Decision-MakingJOURNAL OF CONTINGENCIES AND CRISIS MANAGEMENT, Issue 3 2001Joop F. M. Koppenjan How can we be sure that safety risks are adequately dealt with in the design of complex, innovative projects? In The Netherlands, a number of recent innovative project initiatives have made this a relevant question. These initiatives include projects such as the construction of tunnels using new technologies, the construction of underground facilities that combine several functions, i.e. shopping, parking and transport, and the development of a transport corridor in which rail, road and waterway have been or will be combined. These projects combine several functions and have been, or will be, realised in densely built and populated areas. Although safety regulations for products and systems have been institutionalised through legislation and professional design practices, recent project proposals link systems and their environment in new and complex ways. The risks evolving from these links are unknown and the extent to which they are covered by existing safety approaches is uncertain. In this contribution, we examine how the attention paid to safety can be increased and maintained in the design process of infrastructural projects. First, we discuss the need to reorganise the safety focus in the design process. Then we describe the role of the design process in decision-making for major projects with regard to utility building, town planning and the construction of infrastructures. Third, we elaborate how the focus on safety can be organised within this context, given developments in the field of interactive decision-making and the design and management of interaction processes. We then outline a safety risk management method that can be used to achieve this and, finally, address the conditions that influence the use of this method. [source] Conducting fieldwork with Tarieng communities in southern Laos: Negotiating discursive spaces between neoliberal dogmas and Lao socialist ideologyASIA PACIFIC VIEWPOINT, Issue 2 2010Steeve Daviau Abstract Based on research with ethnic minorities in Laos aimed at understanding how they cope with and negotiate political and economic ,double domination', this article examines the experiences of prolonged fieldwork in a remote Tarieng area in the Annam Range, southern Laos. After briefly reviewing Lao ethnographical policy and practice regarding ethnic minorities, I introduce the Tarieng people. I detail how I initially gained access to these local communities via long-term engagement with a range of development project initiatives. Then, after eight years of conducting such fieldwork in a Tarieng area ,below the radar of the state', I managed to obtain official authorisations to continue research as a graduate student. In this new position, I accessed the field via different negotiations with central, provincial and local official bureaucracies. After detailing this process, back in the field I reveal my strategies to create a discursive space that has allowed me to access dissident Tarieng voices and agency. Finally, I highlight four central elements that have continued to shape my field research: language proficiency, working with research assistants, awareness of political relations and cultural sensitivity, and ethical concerns. These have emerged while the possibilities and constraints of political engagement with the Tarieng people are explored. [source] | |||||||||||||