Primary Cutaneous (primary + cutaneous)

Distribution by Scientific Domains

Terms modified by Primary Cutaneous

  • primary cutaneous amyloidosis
  • primary cutaneous anaplastic large cell lymphoma
  • primary cutaneous b-cell lymphoma
  • primary cutaneous melanoma
  • primary cutaneous squamous cell carcinoma
  • primary cutaneous t-cell lymphoma

  • Selected Abstracts


    Approach to the patient with vulvovaginal complaints

    DERMATOLOGIC THERAPY, Issue 5 2010
    Bethanee J. Schlosser
    ABSTRACT Although vulvovaginal diseases may seem daunting, dermatologists possess all of the requisite tools and skills necessary to comprehensively assess and accurately diagnose primary cutaneous, systemic, and inflammatory diseases that affect the vulva. A simple but comprehensive dermatologic approach to the patient with a vulvovaginal complaint is presented. We begin with a review of the normal vulvar anatomy and normal variants and proceed to the clinical approach with special emphasis on the history, physical examination, and common diagnostic procedures. [source]


    Pericardial effusion as primary manifestation of metastatic cutaneous adenoid cystic carcinoma: Diagnostic cytopathology from an exfoliative sample

    DIAGNOSTIC CYTOPATHOLOGY, Issue 5 2008
    Maxime Benchetritt M.D.
    Abstract Adenoid cystic carcinoma (ACC) occurs not only as a tumor of salivary glands, but also in very unusual locations, such as in the skin. Only very few cases of primary cutaneous of ACC have metastasized to the lymph nodes and lungs. We present a 53-year-old man with metastasis of the pericardium from a primary cutaneous ACC (PCACC) of the scalp, which had been surgically treated 14 years ago. Exfoliative cytologic findings from pericardial effusion included small clusters of basaloid cells with occasional cystlike spaces containing mucoid material. To our knowledge, this is the first case of pericardial metastasis from a PCACC. Diagn. Cytopathol. 2008;36:351,354. © 2008 Wiley-Liss, Inc. [source]


    Pathogenesis and therapy of cutaneous lymphomas , Progress or impasse?

    EXPERIMENTAL DERMATOLOGY, Issue 5 2006
    Reinhard Dummer
    Abstract:, The cutaneous environment hosts a number of hematopoietic neoplasms that are dominated by primary cutaneous (PC) T-cell lymphomas. Recent progress in molecular biology and immunology has provided tools to investigate the pathogenesis and the biology of these neoplasms. This review highlights newest findings concerning the immune biology of CD4+CD56+ hematodermic neoplasms, and PC T-cell and B-cell lymphomas, speculating how these can be translated into more sophisticated, biology-based treatment approaches in the near future. [source]


    Primary cutaneous myxoid spindle cell squamous cell carcinoma: a clinicopathologic study and review of the literature

    JOURNAL OF CUTANEOUS PATHOLOGY, Issue 4 2010
    Aparche Yang
    Mucocutaneous squamous cell carcinoma (SCC) may rarely exhibit intracellular mucin production. Extracellular mucin production is an even rarer finding in SCC that is not well documented in the literature. Here, we report six cases of primary cutaneous and mucocutaneous SCC with prominent extracellular stromal mucin deposition and an epithelial spindle cell component. We propose the term ,yxoid spindle cell SCC' (MSC SCC) to describe the histologic characteristics of these six cases. We also propose a set of histologic and immunohistochemical findings for distinguishing MSC SCC from primary cutaneous and metastatic spindle cell neoplasms including other sarcomatoid carcinomas, myxoid sarcomas and the spindle cell variant of atypical fibroxanthoma (AFX). The criteria can also help discern MSC SCC from spindle cell melanomas, which may rarely show a prominent myxoid stroma. Given the small numbers of cases reported to date, the presence of prominent myxoid stroma in primary cutaneous spindle cell SCC has unknown prognostic significance at this time. Yang A, Hanley A, Velazquez EF, Cassarino DS. Primary cutaneous myxoid spindle cell squamous cell carcinoma: a clinicopathologic study and review of the literature. [source]


    Epidermotropic lesions: a review

    JOURNAL OF CUTANEOUS PATHOLOGY, Issue 10 2009
    Ossama Abbas
    Epidermotropism describes the spread of cells of lymphocytic, epithelial melanocytic, neuroendocrine, histiocytic or muscular origin into the epidermis from an underlying dermal or subcutaneous pathology, that may be primary cutaneous or metastatic. In this review, we aim to discuss the differential diagnosis of epidermotropic lesions and highlight the histological and immunohistochemical characteristics that can help in their differentiation. [source]