Home About us Contact | |||
Prior Findings (prior + finding)
Selected AbstractsStriatal dopamine D2 receptor availability in OCD with and without comorbid social anxiety disorder: preliminary findings,DEPRESSION AND ANXIETY, Issue 1 2008Franklin R. Schneier M.D. Abstract Dopamine D2 receptor availability in the striatum has been reported to be low in generalized social anxiety disorder (GSAD) and obsessive,compulsive disorder (OCD), but it has not been studied in persons with comorbid OCD and GSAD (OCD+GSAD). D2 receptor availability was assessed in 7 subjects with OCD+GSAD, 8 with OCD, and 7 matched healthy comparison (HC) subjects, all unmedicated adults. D2 receptor availability was assessed with single-photon emission computerized tomography (SPECT) to measure binding potential (BP) of the D2 receptor radiotracer [123I] iodobenzamide ([123I]IBZM). Mean striatal [123I]IBZM BP was significantly lower in the OCD+GSAD group (72.58 mL/g, SD=18.17) than in the HC group (118.41 mL/g, SD=45.40; P=.025). Mean BP in the OCD group (93.08 mL/g, SD=36.90) did not differ significantly from the HC group (P=.247). Trait detachment, as measured by the Detachment subscale of the Karolinska Scales of Personality, was negatively correlated with D2 availability across all subjects (rs=,.55, P=.013). Comorbid GSAD and OCD may be associated with decreased availability of D2 receptors in the striatum, consistent with prior findings in GSAD. Prior findings of decreased D2 receptor availability in noncomorbid OCD were not confirmed. Decreased D2 receptor availability was also associated with trait detachment, supporting prior findings in samples of healthy subjects. Depression and Anxiety 0:1,7, 2007. Published 2007 Wiley-Liss, Inc. [source] Sociocultural Variation in Mothers' Control over Children's BehaviorETHOS, Issue 1 2004Associate Professor Tiia Tulviste Prior findings of strict control of middle-class Estonian mothers have not been consistent with middle-class parent,child interaction patterns reported in other studies. The current study sought to find out to what degree the tendency to be more controlling toward children can be explained by the Estonian mothers' own experience of growing up in a totalitarian society. With this aim, measures of maternal controlling attitudes and actual verbal control of children were employed in a second country with a similar history of Soviet occupation,Latvia, and compared with previous data on Estonian, Finnish, and Swedish mono- and bicultural mothers. The questionnaire data revealed that Estonian (including Swedish,Estonian) and Latvian mothers placed higher emphasis on controlling children than did Finnish and Swedish mothers. At the same time, in their real-life interactions, only Estonian mothers living in Estonia exhibited a highly directive conversational style. Finally, the discussion focuses on possible reasons for cultural variability in maternal controlling attitudes and actual control of children. [source] A voxel-based morphometry study of frontal gray matter correlates of impulsivity,HUMAN BRAIN MAPPING, Issue 4 2009Koji Matsuo Abstract Impulsivity is a personality trait exhibited by healthy individuals, but excessive impulsivity is associated with some mental disorders. Lesion and functional neuroimaging studies indicate that the ventromedial prefrontal region (VMPFC), including the orbitofrontal cortex (OFC), anterior cingulate cortex (ACC) and medial prefrontal cortex, and the amygdala may modulate impulsivity and aggression. However, no morphometric study has examined the association between VMPFC and impulsivity. We hypothesized that healthy subjects with high impulsivity would have smaller volumes in these brain regions compared with those with low impulsivity. Sixty-two healthy subjects were studied (age 35.4 ± 12.1 years) using a 1.5-T MRI system. The Barratt impulsiveness scale (BIS) was used to assess impulsivity. Images were processed using an optimized voxel-based morphometry (VBM) protocol. We calculated the correlations between BIS scale scores and the gray matter (GM) and white matter (WM) volumes of VMPFC and amygdala. GM volumes of the left and right OFC were inversely correlated with the BIS total score (P = 0.04 and 0.02, respectively). Left ACC GM volumes had a tendency to be inversely correlated with the BIS total score (P = 0.05). Right OFC GM volumes were inversely correlated with BIS nonplanning impulsivity, and left OFC GM volumes were inversely correlated with motor impulsivity. There were no significant WM volume correlations with impulsivity. The results of this morphometry study indicate that small OFC volume relate to high impulsivity and extend the prior finding that the VMPFC is involved in the circuit modulating impulsivity. Hum Brain Mapp 2009. © 2008 Wiley-Liss, Inc. [source] PROACTIVE POLICING AND ROBBERY RATES ACROSS U.S. CITIES,CRIMINOLOGY, Issue 1 2010CHARIS E. KUBRIN In recent years, criminologists, as well as journalists, have devoted considerable attention to the potential deterrent effect of what is sometimes referred to as "proactive" policing. This policing style entails the vigorous enforcement of laws against relatively minor offenses to prevent more serious crime. The current study examines the effect of proactive policing on robbery rates for a sample of large U.S. cities using an innovative measure developed by Sampson and Cohen (1988). We replicate their cross-sectional analyses using data from 2000 to 2003, which is a period that proactive policing is likely to have become more common than that of the original study,the early 1980s. We also extend their analyses by estimating a more comprehensive regression model that incorporates additional theoretically relevant predictors. Finally, we advance previous research in this area by using panel data, The cross-sectional analyses replicate prior findings of a negative relationship between proactive policing and robbery rates. In addition, our dynamic models suggest that proactive policing is endogenous to changes in robbery rates. When this feedback between robbery and proactive policing is eliminated, we find more evidence to support our finding that proactive policing reduces robbery rates. [source] Striatal dopamine D2 receptor availability in OCD with and without comorbid social anxiety disorder: preliminary findings,DEPRESSION AND ANXIETY, Issue 1 2008Franklin R. Schneier M.D. Abstract Dopamine D2 receptor availability in the striatum has been reported to be low in generalized social anxiety disorder (GSAD) and obsessive,compulsive disorder (OCD), but it has not been studied in persons with comorbid OCD and GSAD (OCD+GSAD). D2 receptor availability was assessed in 7 subjects with OCD+GSAD, 8 with OCD, and 7 matched healthy comparison (HC) subjects, all unmedicated adults. D2 receptor availability was assessed with single-photon emission computerized tomography (SPECT) to measure binding potential (BP) of the D2 receptor radiotracer [123I] iodobenzamide ([123I]IBZM). Mean striatal [123I]IBZM BP was significantly lower in the OCD+GSAD group (72.58 mL/g, SD=18.17) than in the HC group (118.41 mL/g, SD=45.40; P=.025). Mean BP in the OCD group (93.08 mL/g, SD=36.90) did not differ significantly from the HC group (P=.247). Trait detachment, as measured by the Detachment subscale of the Karolinska Scales of Personality, was negatively correlated with D2 availability across all subjects (rs=,.55, P=.013). Comorbid GSAD and OCD may be associated with decreased availability of D2 receptors in the striatum, consistent with prior findings in GSAD. Prior findings of decreased D2 receptor availability in noncomorbid OCD were not confirmed. Decreased D2 receptor availability was also associated with trait detachment, supporting prior findings in samples of healthy subjects. Depression and Anxiety 0:1,7, 2007. Published 2007 Wiley-Liss, Inc. [source] Predicting academic success with the Big 5 rated from different points of view: Self-rated, other rated and fakedEUROPEAN JOURNAL OF PERSONALITY, Issue 4 2010Matthias Ziegler Abstract Self-ratings of personality predict academic success above general intelligence. The present study replicated these findings and investigated the increment of other-ratings or intentionally distorted self-ratings. Participants (N,=,145) had to compile a personality questionnaire twice. First they were given neutral instructions. The second time they were asked to imagine a specific applicant setting. Furthermore, two peers rated each participant. Additionally, verbal, numerical and figural reasoning scores were obtained. Grades on a statistics exam obtained 2 months later served as the criterion. Results replicated prior findings and showed incremental validity for self- and other-rated personality, which was stable after controlling for intelligence. Faking had no impact on the domain-score level, but results on the facet-score level were less encouraging. Copyright © 2010 John Wiley & Sons, Ltd. [source] Do local properties function as cues for musical key perception?,JAPANESE PSYCHOLOGICAL RESEARCH, Issue 2 2009RIE MATSUNAGA Abstract:, A global property (i.e., pitch set) of a melody appears to serve as a primary cue for key identification. Previous studies have proposed specific local properties in a melody (e.g., the augmented fourth, the perfect fifth, etc.) that may function as further cues. However, the role of the latter in key identification is controversial. The present study was designed to investigate what kinds of local properties, if any, function as reliable cues for key identification. Listeners were asked to identify keys for 450 melodies that consisted of the same pitch set, but which differed in sequential constraints. Using multiple discriminant analyses, we evaluated relative contributions of as many kinds of local properties as possible (e.g., single intervals, single pitch classes in each sequential position, etc.). The results showed that, except for the pitch class of the final tone, for which interpretation should be taken cautiously, none of the specific local properties examined contributed significantly to key identification. This finding suggests that, contrary to prior findings, key identification is derived from unidentified properties other than the specific local properties. [source] The White,Coat Effect: Physician Attire and Perceived Authority, Friendliness, and AttractivenessJOURNAL OF APPLIED SOCIAL PSYCHOLOGY, Issue 12 2004Gary L. Brase Although previous studies have evaluated the effects of attire on doctor,patient interaction, the common assumption of a tradeoff between perceptions of medical authority/ status versus trustworthiness/openness has not been established. Thirty,eight male and 40 female participants rated their perceptions of same, and opposite,gender models who all were identified as doctors, but who were wearing different attire. The results indicate that authority and trust are not opposing factors and that a white coat and formal attire are clearly superior to casual attire. Additionally, perceptions of attractiveness of same, and opposite,gender doctors were rated, finding gender differences in perceptions different from, but theoretically similar to, prior findings. For females rating male models, perceptions of authority and attractiveness appear to be related. [source] Psychopathy and Axis I psychiatric disorders among criminal offenders: relationships to impulsive and proactive aggressionAGGRESSIVE BEHAVIOR, Issue 1 2010Marc T. Swogger Abstract Both psychopathology and aggression are heterogeneous constructs. Determining which forms of psychopathology relate to risk for different classes of aggressive behavior has implications for risk recognition and management. This study examined the relationships of impulsive aggression (IA) and proactive aggression (PA) to psychopathy and symptoms of several Diagnostic and Statistical Manual Axis I disorders in a sample of criminal offenders. Results replicated prior findings from community samples of a broad relationship between psychopathology and IA. PA was related only to psychopathy. An interaction was found whereby IA was associated with impulsive,antisocial traits of psychopathy only for individuals with moderate to high levels of generalized anxiety. Results indicate that assessing and treating several Axis I disorders in offenders may decrease risk for IA. Moreover, current findings raise the possibility that generalized anxiety is a key, modifiable component of the relationship between IA and impulsive,antisocial traits. Aggr. Behav. 36:45,53, 2010. © 2009 Wiley-Liss, Inc. [source] A prospective analysis of life events, problem behaviours and depression in adults with intellectual disabilityJOURNAL OF INTELLECTUAL DISABILITY RESEARCH, Issue 4 2006A. J. Esbensen Abstract Background Life events have consistently been found to be associated with behaviour problems and depression among individuals with intellectual disability (ID). However, prior findings have typically been based on correlational or retrospective analyses of case files. The current study attempted to replicate prior findings from life events with concurrent data and extend them to the prospective prediction of behaviour problems and depression. The influence of impact ratings of life events was also explored. Methods Seventy-four informants rated 104 adults with ID on measures of life events, behaviour problems and depressive symptoms. Life events were rated as having either a positive, negative or no impact on the life of the individual with ID. Measures were completed twice, at a 4-month interval. Results Behaviour problems were both correlated with and predicted by frequency counts of life events and life events perceived as negative. However, the predictive ability depended on which measure of problem behaviour was selected. Positive life events were not associated with concurrent behaviour problems. Depressive symptoms were correlated with all life changes, but only predicted by frequency counts of life events and life events perceived as negative. Again, the predictive ability depended on which measure of depression was selected. Findings were corroborated with a group of individuals with clinical diagnoses of major depression. Conclusions Frequency counts of all life events and life events perceived as negative play a role in the development of behaviour problems and depressive symptoms among adults with ID. The results have implications for interventions for behaviour problems following a life event, and for reducing depressive symptoms for adults with mild ID. [source] Acoustic Startle Reactivity During Acute Alcohol Withdrawal in Rats That Differ in Genetic Predisposition Toward Alcohol Drinking: Effect of Stimulus CharacteristicsALCOHOLISM, Issue 5 2004Julia A. Chester Abstract: Background: We have previously reported an association between greater alcohol withdrawal magnitude after a single alcohol exposure and a genetic predisposition toward low alcohol drinking in rats selectively bred for differences in alcohol intake when acoustic startle reactivity to a tone stimulus was used to index acute alcohol withdrawal. The purpose of this study was to examine whether the quality of the acoustic startle stimulus (noise versus tone) is important for detecting a genetic relationship between alcohol withdrawal magnitude and alcohol drinking behavior. Methods: Alcohol-naive male rats selectively bred for high alcohol intake [alcohol-preferring (P), high-alcohol-drinking (HAD)1, and HAD2] or low alcohol intake [alcohol-nonpreferring (NP), low-alcohol-drinking (LAD)1, and LAD2] received a single intragastric infusion of water or alcohol (4.0 g/20.3 ml/kg; 25% v/v), and acoustic startle test sessions were given at 14, 16, 18, 20, and 24 hr after infusion. Each test session consisted of a 5-min acclimation period followed by random presentation of various white noise stimuli (90, 100, 110, and 120 dB.) Results: Line differences in acoustic startle magnitude under control conditions were present in all three pairs of selectively bred lines; P rats showed a greater startle magnitude relative to NP rats, whereas both LAD lines showed a greater startle magnitude relative to both HAD lines. During alcohol withdrawal, the P, HAD1, and HAD2 lines showed enhanced startle magnitude compared with their water-treated controls. No change in startle magnitude during alcohol withdrawal was found in the NP, LAD1, or LAD2 lines. Conclusions: In contrast to our prior findings, these results showed a genetic association between high alcohol drinking and a greater startle response magnitude to a noise stimulus during alcohol withdrawal. It seems that the genetic association between alcohol drinking and alcohol withdrawal, as assessed by the acoustic startle response, depends on the quality of the acoustic startle stimulus. [source] Salty and Sour Taste Characteristics and Risk of AlcoholismALCOHOLISM, Issue 6 2003Kristen A. Sandstrom Background: This study examined gustatory measures (intensity and hedonic values of salt and citric acid solutions) that have been reported to differentiate nonalcoholics who are at risk of alcoholism by virtue of having an alcoholic father (PHP) from those with no such paternal history (PHN). The study tested the hypothesis that PHPs perceive salty and sour solutions to be more intense and less pleasurable than do PHNs. Methods: A total of 112 nonalcoholic subjects (44.7% male and 40.2% PHP) provided intensity and pleasantness ratings for a series of salty and sour solutions in varying concentrations. Results: PHP subjects rated salty solutions as more unpleasant than PHN subjects. PHP subjects also showed higher mean sour intensity ratings and less preference for sour solutions than PHN subjects. Conclusions: This study replicates and extends prior findings of salty and sour taste differences as a function of paternal history of alcoholism. Further research is needed to replicate these findings in other populations and to examine their implications for the transmission of alcoholism risk. [source] Mental rotation delays the heart beat: Probing the central processing bottleneckPSYCHOPHYSIOLOGY, Issue 5 2003J. Richard Jennings Abstract We tested the hypothesis that mental rotation would delay response-related processing as indicated by transient slowing of the heart beat. Thirty college-age subjects (half female) were presented with normal and mirror image letters rotated at 0, 60, 120, and 180°. Three letters were assigned to a right-hand response; a separate three to a left-hand response. Responses were only required for letters in one orientation, mirror or normal. Continuous measures of interbeat interval (IBI) of the heart, respiration, and muscle tension were collected. Performance results were largely consistent with prior findings. Greater angular displacement of the stimuli was associated with greater lengthening of IBI immediately after the stimulus. IBI was influenced equally by angle of rotation in respond and inhibit trials. The lengthening of IBI was interpreted as due to a delay in response selection and execution due to mental rotation. [source] Detecting acute confusion in older adults: Comparing clinical reasoning of nurses working in acute, long-term, and community health care environmentsRESEARCH IN NURSING & HEALTH, Issue 3 2003Marianne C. McCarthy Abstract In an article on a previous study involving hospitalized older adults (McCarthy, 2003), it was argued that the theory of situated clinical reasoning explains why nurses often fail to recognize acute confusion. Further, the theory illuminates how nurses' perspectives toward health in aging affect the ways they regard and ultimately deal with older people in this particular clinical situation. The purpose of the current study was to challenge and refine the theory by exploring the influence of different care environments on clinical reasoning related to acute confusion. Following a period of participant observation, a purposive sample of 30 nurses, 10 each from a teaching hospital, a long-term facility, and a home care agency, participated in semistructured interviews. Dimensional analysis provided the methodological framework for data collection and interpretation. The results reinforce prior findings that the ability of nurses to recognize acute confusion and to distinguish it from dementia can be attributed to their personal philosophies about aging. Care environment was identified as a factor that influenced clinical reasoning in limited ways under certain conditions and within certain contexts. © 2003 Wiley Periodicals, Inc. Res Nurs Health 26: 203,212, 2003 [source] The resistance of maxillofacial reconstruction plates to biofilm formation in vitroTHE LARYNGOSCOPE, Issue 11 2003Brian E. Emery MD Abstract Objectives/Hypothesis: Bacterial biofilms, bacteria surrounded by a protective glycocalyx, have been demonstrated on bioimplants placed within and outside of the head and neck region. The presence of the biofilm often makes decontamination of an infected implant impossible, requiring removal of the implant. Infections attributable to biofilm formation within the facial skeleton after reconstruction with implants may result in delayed union, fibrous union, malunion, nonunion, and malocclusion. These complications often require removal of the implant and secondary surgery. Although the incidence of infections necessitating implant removal is relatively low, the increased numbers of implants being placed make this a growing problem. Previous work in the authors laboratory has demonstrated a resistance to biofilm formation on different types of pressure-equalizing tubes. The hypothesis evaluated in the study is that such resistance to biofilm formation is due to the inability of bacteria to adhere to the tubes because of the material's smoothness or surface charge. Study Design: A controlled observational study. Methods: Scanning electron microscopy was used to evaluate the formation of biofilms in vitro for a common strain of Staphylococcus aureus on four implantable materials. The implantable materials included titanium and polylactide resorbable plates. Results: Consistent with the authors' prior findings, they were able to produce bacterial biofilm reliably on a silicone pressure equalizing tube but were unable to demonstrate biofilm formation on the titanium or resorbable implants. Conclusion: The absence of biofilm formation on these implants can best be explained by the surface charge or polarity properties of these materials. These findings are consistent with the relatively low incidence of infections among patients receiving these implants in maxillofacial applications. [source] A Cross-Cultural Look at Assessment Center Practices: Survey Results from Western Europe and North AmericaAPPLIED PSYCHOLOGY, Issue 4 2009Diana E. Krause No recent survey documents assessment center (AC) practices across several countries. Therefore, we analyse AC practices in a sample of 97 organisations from nine countries in Western Europe and North America. We report findings regarding job analysis, dimensions, exercises, additional diagnostic methods, use of technology, assessor characteristics, contents and methods of assessor training, observational systems, information provided to participants, evaluation of participants' reactions, data integration, characteristics of feedback, and features after the AC. Finally, we compare our results with prior findings to identify trends over time and point out features of ACs that could be improved. Face aux défis que soulèvent les centres d'évaluation (AC) dans les organisations internationales, nous proposons un modèle qui rend compte des variations transculturelles dans ces pratiques, variations relevant de données individuelles (la motivation et la qualification des experts en resources humaines), de conditions culturelles (le « contrôle de l'incertitude » et la « distance hiérarchique ») et de réalités institutionnelles (des differences dans le niveau officiel de collectivisme et des divergences en ce qui concerne les normes légales et les lois régissant l'emploi). Ce modèle est exploité pour expliquer les différences dans la planification, l'exécution et l'évaluation des AC dans des organisations situées dans neuf pays d'Europe de l'ouest et d'Amérique du nord. Nous mettons aussi en evidence des tendances sur le long terme dans les pratiques des AC et discutons de l'amélioration de ces pratiques et de l'orientation des futures recherches dans ce domaine. [source] Investigation of the Multidimensional Model of Job Insecurity in China and the USAAPPLIED PSYCHOLOGY, Issue 4 2006Cynthia Lee Il y a plus d'une décennie, Ashford, Lee, and Bobko (1989) ont développé un outil de mesure standard permettant évaluer des niveaux individuels d'insécurité au travail. Les années suivantes, des chercheurs se sont demandé si la totalité des mesures composant cet instrument était nécessaire. Nous avons donc examiné l'utilité des différentes dimensions du test multidimensionnel de l'Insécurité au travail de Ashford et al. (1989) aux Etats Unis et en Chine, en éprouvant et élargissant les conclusions antérieures. Nos résultats suggèrent qu'éliminer les dimensions "caractéristiques du travail" et "impuissance" de l'instrument multidimensionnel initial est prématuré dans les deux cultures. D'autres recherches s'avèrent donc nécessaires pour déterminer l'utilité de cet outil dans sa version complète. Les implications de nos résultats sont discutées. Over a decade ago, Ashford, Lee, and Bobko (1989) developed a standard measure for those interested in assessing levels of individual job insecurity. In ensuing years, some researchers have questioned whether the entire measure is necessary. We examined the usefulness of the components of Ashford et al.'s (1989) multidimensional measure of job insecurity in both the United States and China, as well as replicating and extending prior findings regarding antecedents and consequences. Our results suggest that the call to eliminate job features or powerlessness from the fully composite measure of job insecurity is premature in both cultures. We call for more research on the utility of the fully operationalised measure. Implications of our findings are discussed. [source] |