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Press Reports (press + report)
Selected AbstractsLatest news and product developmentsPRESCRIBER, Issue 3 2007Article first published online: 14 MAR 200 PPIs and hip fracture Treatment with a PPI may increase the risk of hip fracture, with longer use associated with higher risk according to a study in UK patients (J Am Med Assoc 2006;297:2947-53). The case control study compared use of PPIs by 13 556 patients with hip fracture and 135 386 controls in the UK General Practice Research Database. Use of a PPI for more than one year was associated with an increase of 44 per cent in the odds of hip fracture. The risk was higher for longer- term use (59 per cent after four years) and at higher doses (more than doubled with long-term high doses). The mechanism for this possible effect may be impaired calcium absorption associated with hypochlorhydria and reduced bone resorption. CHD NSF Statin prescribing has increased by 30 per cent every year since the publication of the Coronary Heart Disease NSF, the Department of Health says. The estimated number of lives saved attributable to statins had risen to 9700 in 2005. The proportion of patients with acute MI who were given thrombolysis within 30 minutes of admission has increased to 83 per cent. Flu jabs cut pneumonia deaths A US study suggests that flu vaccine protects against death during the flu season in patients admitted with community-acquired pneumonia (Arch Intern Med 2007;167:53-9). Nineteen per cent of patients admitted with pneumonia during the winters of 1999-2003 were known to have been vaccinated against flu. Their risk of death during their hospital stay was 70 per cent lower than that of nonvaccinated individuals. After adjustment for antipneumococcal vaccination and comorbidity, the odds of death were still 39 per cent lower. Model to predict admissions The King's Fund, together with New York University and Health Dialog, has published a model that predicts the risk of emergency hospital admission (see www.kingsfund.org.uk). The model is intended for use by PCTs and draws on data from secondary and primary care to define clinical profiles, allowing patients whose condition is deteriorating to be identified before they need admission. Problem drinking The National Treatment Agency for Substance Misuse (NTA), a special authority within the NHS, has published a critical appraisal of the evidence for various treatments for alcohol problems (www.nta.nhs.uk). The 212-page document estimates that over seven million hazardous or harmful drinkers may benefit from brief interventions by any health workers, and over one million dependent drinkers may benefit from specialist intervention. It concludes that cognitive behavioural approaches to specialist treatment are most effective and that treatment probably accounts for about one-third of improvements made in problem drinking. of patients remained on the same treatment after one year, falling to half at two years and about 40 per cent at three years. Treatment was more frequently stopped for lack of efficacy than for adverse effects. Stopping anti-TNFs Discontinuation of treatment with anti-TNF agents is more common in clinical practice than in clinical trial populations, a French study has found (J Rheumatol 2006;33:2372-5). The retrospective analysis of a single centre's experience of treating 770 patients with etanercept (Enbrel), infliximab (Remicade) or adalimumab (Humira) found that fewer than two-thirds of patients remained on the same treatment after one year, falling to half at two years and about 40 per cent at three years. Treatment was more frequently stopped for lack of efficacy than for adverse effects. There were no statistically significant differences between the three agents but there was a trend for infliximab to be least well tolerated. Generic statin savings The Department of Health has estimated that prescribing simvastatin and pravastatin generically would save £85 million per year. Its analysis of the ,Better care, better value' indicators (see www.productivity.nhs.uk) shows that statin prescribing has increased by 150 per cent in the past five years, with costs totalling £600 million in 2005. The Department says that if every PCT prescribed pravastatin and simvastatin by generic name in only 69 per cent of cases ,the level achieved by the top quarter of trusts ,the savings would be over £85 million a year. Herceptin reporting Press reports of a two-year trial of trastuzumab (Herceptin) were generally accurate in reporting its effectiveness but few reported an increased risk of adverse effects, according to the NHS National Library for Health (www.library.nhs.uk). The Herceptin Adjuvant (HERA) trial (Lancet 2007;369:29-36) found that, after an average follow-up of two years, 3 per cent of women treated with trastuzumab died compared with 5 per cent of controls; estimated three-year survival rates were 92.4 and 89.7 per cent respectively. All four press articles reported these findings accurately, but only two mentioned the increased risk of adverse effects. Updated guidance on CDs The Department of Health has published updated guidance on the strengthened governance requirements for managing controlled drugs, taking into account new regulations that came into force on 1 January (seewww.dh.gov.uk/asset Root/04/14/16/67/04141667.pdf). Statin adherence lowers MI mortality Patients with acute myocar- dial infarction (MI) who take their statins as prescribed are significantly more likely to survive for two to three years than those with low adherence (J Am Med Assoc 2007;297: 177-86). The four-year observational study of 31 455 patients with acute MI found that, compared with those who had taken at least 80 per cent of prescribed daily doses, the risk of death in those with less than 40 per cent adherence was 25 per cent greater over 2.4 years. For individuals with intermediate adherence (40-79 per cent), the risk was 12 per cent greater. Both differences were statistically significant after adjustment for potential confounding factors. The authors believe their finding is explained by differences in adherence rather than healthier behaviour because the excess risk of low adherence was less marked with beta-blockers and not significant for calcium-channel blockers. Improving community medicines management Mental health trusts need to improve medicines management by their community teams and improve information sharing with GPs, the Healthcare Commission has found (www.healthcare commission.org.uk). Its national report revealed limited evidence of pharmacist involvement in community mental health teams, even though 90 per cent of patients were cared for in the community. Only 11 per cent of assertive outreach patients had the tests necessary to ensure safe use of their medicines. Medication reviews found that 46 per cent of patients in mental health trusts and 12 per cent of those in acute trusts were not taking their medication appropriately. The Commission also reported that acute trusts received a complete drug history from GPs for fewer than half of audited patients when they were admitted to hospital, and only 30 per cent of PCTs reported that GPs received adequate information on patients' medicines on discharge. Copyright © 2007 Wiley Interface Ltd [source] No Smoking Gun: Findings From a National Survey of Office-Based Cosmetic Surgery Adverse Event ReportingDERMATOLOGIC SURGERY, Issue 11 2003Rajesh Balkrishnan PhD Background. Because of recent press reports of adverse outcomes, office-based cosmetic surgery has come under intense scrutiny and associated legislative regulatory action. Objective. To assess the safety of office-based cosmetic surgery through a national survey of state agencies that collect information on adverse patient outcomes. Methods. Medical boards or other responsible authorities were contacted in 48 states to obtain records on adverse outcomes from cosmetic surgery procedures performed in an office-based setting. Results. Five states were able to provide complete information regarding 13 cases of adverse outcomes that resulted from office-based cosmetic surgery procedures. Thirteen states had incomplete information or were unable to provide information. The remaining states reported no adverse outcomes. Information collected by state agencies varies greatly and is inadequate to define the safety of office-based cosmetic surgery practice. Conclusions. The need to regulate physician office surgery on the basis of hospital privileges and office certification is not supported by current data. Mandatory reporting of adverse outcomes from office-based surgery is warranted to identify modifiable risk factors and to reduce the risk of adverse outcomes. [source] The Seventh Messenger and Australia 1904,1980: Benjamin Purnell and the House of DavidJOURNAL OF RELIGIOUS HISTORY, Issue 3 2005GUY FEATHERSTONE The Southcottian tradition of the Seven Angelic Messengers of Rev. 10:7 has a long association with millennial belief in Australia. Brought hither by Christian Israelite missionaries in the 1840s, the final three Messengers (Wroe, Jezreel, and Purnell) all journeyed to Australia to win converts. After describing the origins and beliefs of the sects established by these Messengers, this article outlines the impact of Benjamin Purnell's House of David on local Christian Israelites and others. His visit to Melbourne in December 1904 to "ingather" over seventy converts from the Fitzroy congregation is outlined; a comparison is made with J. A. Dowie's missionary tour of the same year. A description of the life the Australians led in Michigan and their attempts to leave the colony and expose Purnell's sexual misconduct are outlined. Despite unfavourable press reports, continuing missionary activity in Melbourne and then in Sydney resulted in further converts leaving for America, and the establishment of a branch community at North Ryde. A comparison of its ethos and that prevailing at Benton Harbor is included. Details of the eventual demise of the North Ryde community are followed by a brief analysis of its place in Australia's religious life. This essay is published to mark the centenary of the departure of the Christian Israelites in February 1905. [source] Should We Have Faith in Faith-Based Social Services?NONPROFIT MANAGEMENT & LEADERSHIP, Issue 1 2002Rhetoric Versus Realistic Expectations Early in his administration, President George W. Bush set forth his Faith-Based Initiative, which would authorize and encourage religious groups to compete for and provide publicly funded social services. This article analyzes the arguments made by supporters of faith-based social services in regard to their underlying values and premises. This analysis forms the basis for examining the managerial track record of faith-based organizations in the delivery of social services. To identify issues and trends within this category of service providers, the authors analyzed press reports of instances of wrong doing in faith-based groups from 1995 to 2001. Findings reveal that faith-based groups appear to be as susceptible to managerial and accountability inadequacies, if not outright wrongdoing, as are nonsectarian service providers. The authors identify implications regarding the credibility of faith-based groups and public trust as they pertain to an enhanced role in the less regulated service system that the president envisions. [source] Attitudes towards German Immigration in South Australia in the post-Second World War Period, 1947-60AUSTRALIAN JOURNAL OF POLITICS AND HISTORY, Issue 4 2005Jan Schmortte Considering the reaction against Germans in Australia during and after the First World War, it is surprising that German immigration to Australia was permitted again soon after the Second World War and even subsidised by the Australian government. Just seven years after the second war fought with Germany within a generation, Australia signed a five-year agreement to permit Germans to immigrate. This article examines the extent of the Australian public's acceptance of this policy during the period from 1947 to 1960. It concentrates on the state of South Australia where some of the earliest settlers in the colony had been of German origin, where their behaviour and achievements had been praised in historical writings about the colony, and where German immigrants may, therefore, have been viewed more positively. Yet there was some suspicion towards and discrimination against Germans in South Australia after 1945. Negative stereotypes of Germans were apparent in comments made by politicians and in press reports. However, these fears were minor and faded even further when more Germans arrived in Australia. [source] | |||||||||||||