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Prenatal Corticosteroids (prenatal + corticosteroid)
Selected AbstractsEffects of antenatal magnesium sulfate and corticosteroid therapy on sleep states of preterm infants,RESEARCH IN NURSING & HEALTH, Issue 4 2006Beth Black Abstract This exploratory longitudinal study was designed to compare the neonatal illness severity, sleep,wake, and respiratory sleep behaviors of preterm infants whose mothers received prenatal corticosteroids and/or magnesium sulfate (MgSO4) with those of infants whose mothers did not receive these medications. The 134 infants were divided into four groups: those whose mothers received MgSO4 only, those who received steroids only, those who received both MgSO4 and steroids, and those who received neither. The groups did not differ on infant characteristics or illness severity. Infants exposed to MgSO4 had more active sleep without rapid eye movement, indicating poorly organized active sleep. The MgSO4 -only group had higher quiet sleep regularity scores and fewer state changes. These findings suggest that fetal exposure to MgSO4 may subtly affect the central nervous system. © 2006 Wiley Periodicals, Inc. Res Nurs Health 29: 269,280, 2006 [source] Who remains undelivered more than seven days after a single course of prenatal corticosteroids and gives birth at less than 34 weeks?AUSTRALIAN AND NEW ZEALAND JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Issue 4 2002KJ McLaughlin ABSTRACT Minimal information exists as to how women who give birth more than seven days after initial corticosteroid treatment, who may benefit from repeat prenatal corticosteroids, differ from women who give birth within seven days, at < 34 weeks gestation. OBJECTIVES To examine the differences, if any, between women who received a single course of prenatal corticosteroids and remained undelivered more than seven days later and women who gave birth within seven days of treatment, at < 34 weeks gestation. DESIGN Retrospective cohort. Setting Women's and Children's Hospital, Adelaide. Population Women who gave birth at < 34 weeks gestation from 1 January 1994 to 31 December 1996. Methods Data were extracted from medical records and retrieved from the hospital's database. Main potential predictors collected Prenatal corticosteroid exposure, reason for risk of preterm birth, maternal demographics and previous and current obstetric history. Results Of the 506 women, 122 (24%) remained undelivered more than seven days following prenatal corticosteroid therapy. Initial corticosteroid treatment was given on average 1.6 weeks earlier to women who remained undelivered more than seven days after treatment. Women who were given prenatal corticosteroids for placenta praevia (RR 6.03, 95% CI 2.67-13.61, p < 0.01) or cervical incompetence (RR 3.40, 95% CI 1.06-10.95, p = 0.04) were more likely to give birth more than seven days after corticosteroid treatment. Conclusions Women who give birth very preterm, who remain undelivered more than seven days after prenatal corticosteroids, differ in the reasons for and timing of their first course from women who give birth within seven days. [source] | ||||||||||