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Preliminary Way (preliminary + way)
Selected AbstractsStructure,activity relationships for the mutagenicity and carcinogenicity of simple and ,-, unsaturated aldehydesENVIRONMENTAL AND MOLECULAR MUTAGENESIS, Issue 3 2003Romualdo Benigni Abstract Aldehydes are important industrial compounds that are used for the synthesis of chemicals and pharmaceuticals and as solvents, food additives, and disinfectants. Because of their reactivity, aldehydes are able to interact with electron-rich biological macromolecules and adverse health effects have been reported, including general toxicity, allergenic reactions, mutagenicity, and carcinogenicity. The cost, time, and number of animals necessary to adequately screen these chemicals places serious limitations on the number of aldehydes whose health potential can be studied and points to the need of using alternative methods for assessing, at least in a preliminary way, the risks associated with the use of aldehydes. A method of choice is the study of quantitative structure,activity relationships (QSARs). In the present work, we present QSAR models for the mutagenicity and carcinogenicity of simple aldehydes and ,-, unsaturated aldehydes. The models point to the role of electrophilicity, bulkiness, and hydrophobicity in the genotoxic activity of the aldehydes and lend themselves to the prediction of the activity of other untested chemicals of the same class. Environ. Mol. Mutagen. 42:136,143, 2003. © 2003 Wiley-Liss, Inc. [source] The Poetics of "Divine Chit-Chat": Rethinking the Conversation PoemsLITERATURE COMPASS (ELECTRONIC), Issue 3 2006Robert Koelzer This article focuses on the Romantic genre, pioneered by Coleridge in the 1790s, of the "conversation poem." It provides a survey of influential twentieth-century critics and criticism of the form; more to the point, however, it seeks to problematize our inherited ideas about the conversation poem by examining some of the assumptions (and mischaracterizations) that have informed the critical construction of this genre. In short, this article argues that the conversation poem's generic relationship to conversation has not been explained in sufficient depth. It attempts, in a preliminary way, to redress this insufficiency by outlining what its author calls a poetics of conversation , that is, the compositional techniques whereby a poet works out a fully-realized conversational form , through a reading of the "original" conversation poem: Coleridge's "The Nightingale: A Conversational Poem" of 1798. [source] What Do We Do Wednesday?CANADIAN REVIEW OF SOCIOLOGY/REVUE CANADIENNE DE SOCIOLOGIE, Issue 1 2009On Beginning the Class as University-Specific Work: A Preliminary Study Je pose la question: «Qu'en est-il au juste des activités des universités qui en font précisément des universités?» Et je l'aborde ethnométhodologiquement d'une manière préliminaire, en examinant la réalisation interactionnelle de ce qu'est, pour les parties présentes, d'une manière observable et rapportable, le début d'un cours à l'université. Rechercher une réponse à la question, étant donné les renseignements sur cassette audio disponibles, provoque l'utilisation réfléchie par les membres des ressources contextuelles catégorielles, séquentielles et autres rendues disponibles par l'encadrement. Les questions de la signification analytique de la méthode documentaire d'interprétation et de l'abstraction des catégories d'adhésion sont brièvement reprises. I pose the question,just what is university-specific about the activities of universities?,and address it ethnomethodologically in a preliminary way by examining the interactional accomplishment of what is, for the parties present, observably and reportably the beginning of a class at a university. Pursuing an answer to the question, given the audiotaped data to hand, turns on members' reflexive use of the categorical, sequential, and otherwise contextual resources made available by the setting. The questions of the analytic significance of the documentary method of interpretation and of the abstractness of membership categories are briefly taken up. [source] A Break from the Past: Impacts and Implications of the Canada Foundation for Innovation and the Canada Research Chairs Initiatives,CANADIAN REVIEW OF SOCIOLOGY/REVUE CANADIENNE DE SOCIOLOGIE, Issue 3 2002Claire Polster Cet article cherche à explorer de façon préliminaire la nature et l'im-pact de deux récentes initiatives fédérales concernant la recherche universitaire, soit la Fondation canadienne pour l'innovation et les Chaires de recherche du Canada. Une description des faits saillants de ces initiatives sera suivie d'une analyse centrée sur la manière dont ces initiatives contribuent à réorganiser les relations sociales entre les universités, le gouvernement, le secteur privé et le public général, de même que les relations au sein même de ces organismes. L'analyse considère ègalement les conséquences de cette réorganisation pour les groupes en cause afin d'éclairer les discussions et actions qu'ont engendrées ces initiatives singulières et significatives pour les études supérieures au Canada. This paper aims to explore,in a broad and preliminary way,the nature and impacts of two recent federal initiatives related to university research, namely the creation of the Canada Foundation for Innovation and the Canada Research Chairs Program. After describing and highlighting key features of these initiatives, the paper examines how they are helping to reorganize social relations within and between universities, government, the private sector, and the general public. It also considers some implications of these changes for the various parties involved, as a means of informing the latter's discussions of, and responses to, these unique and significant developments in Canadian higher education. [source] |