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Practical Role (practical + role)

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Humanities and Social Sciences	50%

Selected Abstracts

Adapted DAX-8 fractionation method for dissolved organic matter (DOM) from soils: development, calibration with test components and application to contrasting soil solutions

EUROPEAN JOURNAL OF SOIL SCIENCE, Issue 6 2009
F. Amery
Summary Most methods to fractionate natural dissolved organic matter (DOM) rely on sorption of acidified DOM samples onto XAD-8 or DAX-8 resin. Procedural differences among methods are large and their interpretation is limited because there is a lack of calibration with DOM model molecules. An automated column-based DOM fractionation method was set up for 10-ml DOM samples, dividing DOM into hydrophilic (HPI), hydrophobic acid (HPOA) and hydrophobic neutral (HPON) fractions. Fifteen DOM model components were tested in isolation and in combination. Three reference DOM samples of the International Humic Substances Society were included to facilitate comparison with other methods. Aliphatic low-molecular-weight acids (LMWAs) and carbohydrates were classified as HPI DOM, but some LMWAs showed also a partial HPO character. Aromatic LMWAs and polyphenols partitioned in the HPOA fraction, menadione (quinone) and geraniol (terpenoid) in HPON DOM. Molecules with log Kow > 0.5 had negligible HPI fractions. The HPO molecules except geraniol had specific UV absorbance (SUVA, measure for aromaticity) >3 litres g,1 cm,1 while HPI molecules had SUVA values <3 litres g,1 cm,1. Distributions of DOM from eight soils ranged from 31 to 72% HPI, 25 to 46% HPOA and 2 to 28% HPON of total dissolved organic carbon. The SUVA of the HPI DOM was consistently smaller compared with the HPOA DOM. The SUVA of the natural DOM samples was not explained statistically by fractionation and the variation coefficient of SUVA among samples was not reduced by fractionation. Hence, fractionation did not reduce the variability in this DOM property, which casts some doubts on the practical role of DOM fractionation in predicting DOM properties. [source]

Teaching & Learning Guide for: Moral Realism and Moral Nonnaturalism

PHILOSOPHY COMPASS (ELECTRONIC), Issue 3 2008
Stephen Finlay
Authors' Introduction Metaethics is a perennially popular subject, but one that can be challenging to study and teach. As it consists in an array of questions about ethics, it is really a mix of (at least) applied metaphysics, epistemology, philosophy of language, and mind. The seminal texts therefore arise out of, and often assume competence with, a variety of different literatures. It can be taught thematically, but this sample syllabus offers a dialectical approach, focused on metaphysical debate over moral realism, which spans the century of debate launched and framed by G. E. Moore's Principia Ethica. The territory and literature are, however, vast. So, this syllabus is highly selective. A thorough metaethics course might also include more topical examination of moral supervenience, moral motivation, moral epistemology, and the rational authority of morality. Authors Recommend: Alexander Miller, An Introduction to Contemporary Metaethics (Cambridge: Polity Press, 2003). This is one of the few clear, accessible, and comprehensive surveys of the subject, written by someone sympathetic with moral naturalism. David Brink, Moral Realism and the Foundations of Ethics (Cambridge: Cambridge University Press, 1989). Brink rehabilitates naturalism about moral facts by employing a causal semantics and natural kinds model of moral thought and discourse. Michael Smith, The Moral Problem (Oxford: Blackwell, 1994). Smith's book frames the debate as driven by a tension between the objectivity of morality and its practical role, offering a solution in terms of a response-dependent account of practical rationality. Gilbert Harman and Judith Jarvis Thomson, Moral Relativism & Moral Objectivity (Cambridge, MA: Blackwell, 1996). Harman argues against the objectivity of moral value, while Thomson defends it. Each then responds to the other. Frank Jackson, From Metaphysics to Ethics (Oxford: Clarendon Press, 1998). Jackson argues that reductive conceptual analysis is possible in ethics, offering a unique naturalistic account of moral properties and facts. Mark Timmons, Morality without Foundations (Oxford: Oxford University Press, 1999). Timmons distinguishes moral cognitivism from moral realism, interpreting moral judgments as beliefs that have cognitive content but do not describe moral reality. He also provides a particularly illuminating discussion of nonanalytic naturalism. Philippa Foot, Natural Goodness (New York, NY: Oxford University Press, 2001). A Neo-Aristotelian perspective: moral facts are natural facts about the proper functioning of human beings. Russ Shafer-Landau, Moral Realism: A Defence (New York, NY: Oxford University Press, 2003). In this recent defense of a Moorean, nonnaturalist position, Shafer-Landau engages rival positions in a remarkably thorough manner. Terence Cuneo, The Normative Web (New York, NY: Oxford University Press, 2007). Cuneo argues for a robust version of moral realism, developing a parity argument based on the similarities between epistemic and moral facts. Mark Schroeder, Slaves of the Passions (New York, NY: Oxford University Press, 2007). Schroeder defends a reductive form of naturalism in the tradition of Hume, identifying moral and normative facts with natural facts about agents' desires. Online Materials: PEA Soup: http://peasoup.typepad.com A blog devoted to philosophy, ethics, and academia. Its contributors include many active and prominent metaethicists, who regularly post about the moral realism and naturalism debates. Metaethics Bibliography: http://www.lenmanethicsbibliography.group.shef.ac.uk/Bib.htm Maintained by James Lenman, professor of philosophy at the University of Sheffield, this online resource provides a selective list of published research in metaethics. Stanford Encyclopedia of Philosophy: http://plato.stanford.edu See especially the entries under ,metaethics'. Sample Syllabus: Topics for Lecture & Discussion Note: unless indicated otherwise, all the readings are found in R. Shafer-Landau and T. Cuneo, eds., Foundations of Ethics: An Anthology (Malden: Blackwell, 2007). (FE) Week 1: Realism I (Classic Nonnaturalism) G. E. Moore, Principia Ethica, 2nd ed. (FE ch. 35). W. K. Frankena, ,The Naturalistic Fallacy,'Mind 48 (1939): 464,77. S. Finlay, ,Four Faces of Moral Realism', Philosophy Compass 2/6 (2007): 820,49 [DOI: 10.1111/j.1747-9991.2007.00100.x]. Week 2: Antirealism I (Classic Expressivism) A. J. Ayer, ,Critique of Ethics and Theology' (1952) (FE ch. 3). C. Stevenson, ,The Nature of Ethical Disagreement' (1963) (FE ch. 28). Week 3: Antirealism II (Error Theory) J. L. Mackie, ,The Subjectivity of Values' (1977) (FE ch. 1). R. Joyce, Excerpt from The Myth of Morality (2001) (FE ch. 2). Week 4: Realism II (Nonanalytic Naturalism) R. Boyd, ,How to be a Moral Realist' (1988) (FE ch. 13). P. Railton, ,Moral Realism' (1986) (FE ch. 14). T. Horgan and M. Timmons, ,New Wave Moral Realism Meets Moral Twin Earth' (1991) (FE ch. 38). Week 5: Antirealism III (Contemporary Expressivism) A. Gibbard, ,The Reasons of a Living Being' (2002) (FE ch. 6). S. Blackburn, ,How To Be an Ethical Anti-Realist' (1993) (FE ch. 4). T. Horgan and M. Timmons, ,Nondescriptivist Cognitivism' (2000) (FE ch. 5). W. Sinnott-Armstrong, ,Expressivism and Embedding' (2000) (FE ch. 37). Week 6: Realism III (Sensibility Theory) J. McDowell, ,Values and Secondary Qualities' (1985) (FE ch. 11). D. Wiggins, ,A Sensible Subjectivism' (1991) (FE ch. 12). Week 7: Realism IV (Subjectivism) & Antirealism IV (Constructivism) R. Firth, ,Ethical Absolutism and the Ideal Observer' (1952) (FE ch. 9). G. Harman, ,Moral Relativism Defended' (1975) (FE ch. 7). C. Korsgaard, ,The Authority of Reflection' (1996) (FE ch. 8). Week 8: Realism V (Contemporary Nonnaturalism) R. Shafer-Landau, ,Ethics as Philosophy' (2006) (FE ch. 16). T. M. Scanlon, What We Owe to Each Other (Cambridge, MA: Harvard University Press, 1998), ch. 1. T, Cuneo, ,Recent Faces of Moral Nonnaturalism', Philosophy Compass 2/6 (2007): 850,79 [DOI: 10.1111/j.1747-9991.2007.00102.x]. [source]

Prostate-specific antigen velocity (PSAV): a practical role for PSA?

ANZ JOURNAL OF SURGERY, Issue 10 2009
Ruban Thanigasalam
Abstract Background:, Prostate cancer is a leading cause of morbidity and mortality in Australian men. Early detection and treatment are critical to patient outcome, but detection is often difficult because of the limited accuracy of available tests. This paper assesses whether the use of prostate specific antigen kinetics has a practical use in the contemporary urological setting. Methods:, A Medline literature review was performed examining related articles on the commonly available tests for prostate cancer, what they mean, their limited accuracy in cancer detection, and how this accuracy can be improved. Discussion:, Detection of significant organ-confined prostate cancer should be the goal of general practitioners and urologists alike. Prostate-specific antigen and digital rectal examination are commonly used but lack specificity and sensitivity, especially for small organ-confined cancers. The additional use of prostate-specific antigen velocity may enhance the specificity and sensitivity of detection. [source]

POVERTY AND INEQUALITY: CHALLENGES FOR THE IAB: IAB PRESIDENTIAL ADDRESS

BIOETHICS, Issue 5-6 2005
FLORENCIA LUNA
ABSTRACT This paper focuses on poverty and inequality in the world today. First, it points out how this topic is a main concern for the IAB. Second, it proposes ,new' theoretical tools in order to analyze global justice and our obligations towards the needy. I present John Rawls's denial that the egalitarian principle can be applied to the global sphere, his proposed weak duty of assistance, and his consideration of endemic poverty as essentially homegrown. In opposition, I focus on Thomas Pogge as representative of a cosmopolitan view who also holds a critical position towards the international systems which allow and cause poverty. I endorse the general normative proposal that defends every human being as an ultimate unit of moral concern, as well as the strategy of moving away from the charity model of bilateral aid to the realm of rights and duties. These ideas should redesign and broaden the normative and practical roles of institutions, and should also help provide a new approach on bioethical issues such as drug patenting or the imbalance in global research and neglected diseases. [source]