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Potential Solutions (potential + solution)
Selected AbstractsHydrovinylation of 1,3-Dienes: A New Protocol, and Asymmetric Variation, and a Potential Solution to the Exocyclic Side Chain Stereochemistry Problem.CHEMINFORM, Issue 21 2006Aibin Zhang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Parental mental illness: a review of barriers and issues for working with families and childrenJOURNAL OF PSYCHIATRIC & MENTAL HEALTH NURSING, Issue 9 2009D. MAYBERY phd Accessible summary For the psychiatric workforce to become family focused (particularly in relation to children) there is a clear need for family sensitive policies and procedures, managerial and organizational support and well-targeted and sustained workforce training. However, there are multiple barriers to the adult mental health workforce becoming family focused including: ,,Some adult mental health services do not identify consumers who are parents and subsequently do not respond to children, parenting and family needs. ,,Organizations often do not have adequate family and child friendly policies and procedures. ,,The adult mental health workforce lacks skills and knowledge about families, children and parenting. ,,The workforce needs to increase encouragement of consumers to include family members and dependent children in treatment of the ill parent including the provision of psycho-education. Abstract Many consumers of psychiatric services are parents, making these services the opportunistic point for supporting consumers' children. While evidence suggests that assisting such children improves their mental health, there is a large gulf between what psychiatric services should (or could) provide and what they do in practice. This paper summarizes the constraining barriers and issues for the psychiatric workforce according to: (1) policy and management; (2) interagency collaboration; (3) worker attitude, skill and knowledge; (4) the parent-consumer; and (5) the consumer's family, including children. Potential solutions are presented, with a particular focus on the hierarchical nature of these barriers. Recommendations are made, including organizational audits to identify the most pressing barriers that impede family sensitive practice. [source] Lost in transition: Challenges in the expanding field of adult genetics,AMERICAN JOURNAL OF MEDICAL GENETICS, Issue 4 2006Matthew R.G. Taylor Abstract It is increasingly clear that medical genetics has broad relevance in adult clinical medicine. More adult patients with genetic conditions are being recognized, genetic testing for adult-onset genetic conditions is expanding, and children with genetic conditions are now more likely to survive to adulthood. While the number of patients who could benefit from medical genetic services increases, adult care providers are less well educated about clinical genetics and are not sufficiently prepared to meet the growing needs of this population. Genetics professionals may also be ill-suited for this challenge, since geneticists and genetic counselors have traditionally had greater experience in pediatric and prenatal settings. Communication between primary care physicians who treat adults and the genetics community is currently suboptimal and the identification and subsequent referral of adult patients for genetic services need improvement. Finally, published guidelines that address how to deliver genetic services to adult patients are unavailable for many genetic conditions. In this article we address the challenges of transitioning genetics services from traditional, and largely pediatric-based models to paradigms that can best address the needs of adult patients with genetic conditions. Potential solutions and the practicality of implementation of a team-based approach to adult genetic medicine, including the application of genetic counseling, are also discussed. © 2006 Wiley-Liss, Inc. [source] Hypothesis: Research in Otolaryngology Is Essential for Continued Improvement in Health Care,THE LARYNGOSCOPE, Issue 6 2002Robert H. Mathog MD Abstract The present report, in the form of a research proposal, is based on the hypothesis that research in otolaryngology is essential for continued improvement in health care. Examples of advances in otolaryngology as a result of research are noted, but for continued success, otolaryngology must maintain and find better ways to train clinically directed researchers. Traditional methods of training such as hands-on experience, courses in the basic principles of research, protected time, and mentoring are discussed and evaluated. Barriers to success such as age, time, and debt are noted. Potential solutions are presented with an emphasis on integration of the research and clinical training. Success of faculty will continue to depend on laboratory and financial support, technical assistance, protected time, salary equivalent to other faculty, and accessibility of research funds. For research to gain support and enthusiasm and to keep it strong and productive, cost-effectiveness and value must be recognized. [source] Multimode Project Scheduling Based on Particle Swarm OptimizationCOMPUTER-AIDED CIVIL AND INFRASTRUCTURE ENGINEERING, Issue 2 2006Hong Zhang This article introduces a methodology for solving the MRCPSP based on particle swarm optimization (PSO) that has not been utilized for this and other construction-related problems. The framework of the PSO-based methodology is developed. A particle representation formulation is proposed to represent the potential solution to the MRCPSP in terms of priority combination and mode combination for activities. Each particle-represented solution should be checked against the nonrenewable resource infeasibility and will be handled by adjusting the mode combination. The feasible particle-represented solution is transformed to a schedule through a serial generation scheme. Experimental analyses are presented to investigate the performance of the proposed methodology. [source] Measures, perceptions and scaling patterns of aggregated species distributionsECOGRAPHY, Issue 1 2010Cang Hui Non-random (aggregated) species distributions arise from habitat heterogeneity and nonlinear biotic processes. A comprehensive understanding of the concept of aggregation, as well as its measurement, is pivotal to our understanding of species distributions and macroecological patterns. Here, using an individual-based model, we analyzed opinions on the concept of aggregation from the public and experts (trained ecologists), in addition to those calculated from a variety of aggregation indices. Three forms of scaling patterns (logarithmic, power-law and lognormal) and four groups of scaling trajectories emerged. The experts showed no significant difference from the public, although with a much lower deviation. The public opinion was partially influenced by the abundance of individuals in the spatial map, which was not found in the experts. With the increase of resolution (decrease of grain), aggregation indices showed a general trend from significantly different to significantly similar to the expert opinion. The over-dispersion index (i.e. the clumping parameter k in the negative binomial distribution) performed, at certain scales, as the closest index to the expert opinion. Examining performance of aggregation measures from different groups of scaling patterns was proposed as a practical way of analyzing spatial structures. The categorization of the scaling patterns of aggregation measures, as well as their over- and in-sensitivity towards spatial structures, thus not only provides a potential solution to the modifiable areal unit problem, but also unveils the interrelationship among the concept, measures and perceptions of aggregated species distributions. [source] Blinding in clozapine trials: a problem and a potential solutionINTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH, Issue 3 2009Tamar Wohlfarth Abstract Background:,A methodological problem arises when efficacy of clozapine is compared with other antipsychotic medication in double blind randomized studies. Due to the risk of leucopenia and agranulocytosis, patients in the clozapine condition need to have regular blood testing. The problem is that in order to maintain blinding, patients in the comparison conditions need to undergo blood testing as well and this can lead to underestimation of treatment acceptability and efficacy of the comparators. Methods:,A thought experiment considering all possible solutions for the methodological problem. Results:,We propose a special study design that preserves randomization and blinding while at the same time prevents underestimation of the effect in the comparator treatments. In addition, the necessity for blood testing is limited to only a small number of patients who receive comparative treatments. The design involves initial randomization to a sub-study including clozapine and a small comparator arm or to a sub-study that includes only comparator arms. Blood testing is only necessary in the first sub-study. Discussion:,Limitations of the proposed design are discussed. It is noted that this study design may offer a solution to similar situations where blood testing or other types of monitoring (e.g. as with lithium) is required in one but not in all of the treatment arms of a double blind randomized study. Copyright © 2009 John Wiley & Sons, Ltd. [source] Regression modelling of correlated data in ecology: subject-specific and population averaged response patternsJOURNAL OF APPLIED ECOLOGY, Issue 5 2009John Fieberg Summary 1.,Statistical methods that assume independence among observations result in optimistic estimates of uncertainty when applied to correlated data, which are ubiquitous in applied ecological research. Mixed effects models offer a potential solution and rely on the assumption that latent or unobserved characteristics of individuals (i.e. random effects) induce correlation among repeated measurements. However, careful consideration must be given to the interpretation of parameters when using a nonlinear link function (e.g. logit). Mixed model regression parameters reflect the change in the expected response within an individual associated with a change in that individual's covariates [i.e. a subject-specific (SS) interpretation], which may not address a relevant scientific question. In particular, a SS interpretation is not natural for covariates that do not vary within individuals (e.g. gender). 2.,An alternative approach combines the solution to an unbiased estimating equation with robust measures of uncertainty to make inferences regarding predictor,outcome relationships. Regression parameters describe changes in the average response among groups of individuals differing in their covariates [i.e. a population-averaged (PA) interpretation]. 3.,We compare these two approaches [mixed models and generalized estimating equations (GEE)] with illustrative examples from a 3-year study of mallard (Anas platyrhynchos) nest structures. We observe that PA and SS responses differ when modelling binary data, with PA parameters behaving like attenuated versions of SS parameters. Differences between SS and PA parameters increase with the size of among-subject heterogeneity captured by the random effects variance component. Lastly, we illustrate how PA inferences can be derived (post hoc) from fitted generalized and nonlinear-mixed models. 4.,Synthesis and applications. Mixed effects models and GEE offer two viable approaches to modelling correlated data. The preferred method should depend primarily on the research question (i.e. desired parameter interpretation), although operating characteristics of the associated estimation procedures should also be considered. Many applied questions in ecology, wildlife management and conservation biology (including the current illustrative examples) focus on population performance measures (e.g. mean survival or nest success rates) as a function of general landscape features, for which the PA model interpretation, not the more commonly used SS model interpretation may be more natural. [source] Intellectual Property in the Context of e-ScienceJOURNAL OF COMPUTER-MEDIATED COMMUNICATION, Issue 2 2007Dan L. Burk E-science promises to allow globally-distributed collaboration and access to scientific research via computer networks, but e-science development is already encountering difficulty over the intellectual property rights associated with data and networked collaborative activity. The proprietary nature of intellectual property is generally problematic in the practice of science, but such difficulties are likely to be exacerbated in the context of e-science collaboration where the development and use of intellectual resources will likely be distributed among many researchers in a variety of physical locations, often spanning national boundaries. While a potential solution to such problems may reside in the mechanism of "open source" licenses, the organizational structure of scientific research may not map cleanly onto the open source model. Consequently, a firm understanding of not only the technical structure but of the social and communicative structure of e-science will be necessary in order to adapt licensing solutions to the practice of e-science. [source] Effects of Response Format on Difficulty of SAT-Mathematics Items: It's Not the StrategyJOURNAL OF EDUCATIONAL MEASUREMENT, Issue 1 2000Irvin R. Katz Problem-solving strategy is frequently cited as mediating the effects of response format (multiple-choice, constructed response) on item difficulty, yet there are few direct investigations of examinee solution procedures. Fifty-five high school students solved parallel constructed response and multiple-choice items that differed only in the presence of response options. Student performance was videotaped to assess solution strategies. Strategies were categorized as "traditional",those associated with constructed response problem solving (e.g., writing and solving algebraic equations),or "nontraditional",those associated with multiple-choice problem solving (e.g., estimating a potential solution). Surprisingly, participants sometimes adopted nontraditional strategies to solve constructed response items. Furthermore, differences in difficulty between response formats did not correspond to differences in strategy choice: some items showed a format effect on strategy but no effect on difficulty; other items showed the reverse. We interpret these results in light of the relative comprehension challenges posed by the two groups of items. [source] A re-examination of the excess smoothness puzzle when consumers estimate the income processJOURNAL OF FORECASTING, Issue 5 2001Anurag N. Banerjee Abstract The excess smoothness puzzle is explored using a simple version of the permanent income hypothesis. The new feature is that consumers do not know the observed data-generating process for income. Instead they estimate the income process every period using the past income data and update their income forecasts as new data arrive. Two scenarios are examined: first, where the income has a linear deterministic trend and second, where the income has a constant trend. There is a misspecification bias in the estimate of the marginal propensity to consume (MPC). This bias is of second-order importance in the first scenario while it is of first-order importance in the second. We conclude that the second scenario, which may be relevant for less developed countries, may offer a potential solution to the excess smoothness puzzle. Copyright © 2001 John Wiley & Sons, Ltd. [source] The impact of integrated aquaculture,agriculture on small-scale farms in Southern MalawiAGRICULTURAL ECONOMICS, Issue 1 2010Madan M. Dey Aquaculture; Malawi; Participatory research; Technical efficiency Abstract Sustainable agricultural intensification is an urgent challenge for Sub-Saharan Africa. One potential solution is to rely on local farmers' knowledge for improved management of diverse on-farm resources and integration among various farm enterprises. In this article, we analyze the farm-level impact of one recent example, namely the integrated aquaculture,agriculture (IAA) technologies that have been developed and disseminated in a participatory manner in Malawi. Based on a 2004 survey of 315 respondents (166 adopters and 149 nonadopters), we test the hypothesis that adoption of IAA is associated with improved farm productivity and more efficient use of resources. Estimating a technical inefficiency function shows that IAA farms were significantly more efficient compared to nonadopters. IAA farms also had higher total factor productivity, higher farm income per hectare, and higher returns to family labor. [source] Understanding the essential elements of work-based learning and its relevance to everyday clinical practiceJOURNAL OF NURSING MANAGEMENT, Issue 6 2010BSc (Hons) Nurse Practitioner, CAROLINE WILLIAMS RN, Dip N, MSc (Nursing), PGCE (FE), PGCert (Facilitation & life-long learning) williams c. (2010) Journal of Nursing Management 18, 624,632 Understanding the essential elements of work-based learning and its relevance to everyday clinical practice Aim, To critically review the work-based learning literature and explore the implications of the findings for the development of work-based learning programmes. Background, With NHS budgets under increasing pressure, and challenges to the impact of classroom-based learning on patient outcomes, work-based learning is likely to come under increased scrutiny as a potential solution. Evidence from higher education institutions suggests that work-based learning can improve practice, but in many cases it is perceived as little more than on-the-job training to perform tasks. Evaluation, The CINAHL database was searched using the keywords work-based learning, work-place learning and practice-based learning. Those articles that had a focus on post-registration nursing were selected and critically reviewed. Key issues, Using the review of the literature, three key issues were explored. Work-based learning has the potential to change practice. Learning how to learn and critical reflection are key features. For effective work-based learning nurses need to take control of their own learning, receive support to critically reflect on their practice and be empowered to make changes to that practice. Conclusions, A critical review of the literature has identified essential considerations for the implementation of work-based learning. A change in culture from classroom to work-based learning requires careful planning and consideration of learning cultures. Implications for nursing management, To enable effective work-based learning, nurse managers need to develop a learning culture in their workplace. They should ensure that skilled facilitation is provided to support staff with critical reflection and effecting changes in practice. Contribution to New Knowledge, This paper has identified three key issues that need to be considered in the development of work-based learning programmes. [source] Development of fully functional proteins with novel glycosylation via enzymatic glycan trimmingJOURNAL OF PHARMACEUTICAL SCIENCES, Issue 8 2009Melinda L. Toumi Abstract Recombinant glycoproteins present unique challenges to biopharmaceutical development, especially when efficacy is affected by glycosylation. In these cases, optimizing the protein's glycosylation is necessary, but difficult, since the glycan structures cannot be genetically encoded, and glycosylation in nonhuman cell lines can be very different from human glycosylation profiles. We are exploring a potential solution to this problem by designing enzymatic glycan optimization methods to produce proteins with useful glycan compositions. To demonstrate viability of this new approach to generating glycoprotein-based pharmaceuticals, the N -linked glycans of a model glycoprotein, ribonuclease B (RNase B), were modified using an ,-mannosidase to produce a new glycoprotein with different glycan structures. The secondary structure of the native and modified glycoproteins was retained, as monitored using circular dichroism. An assay was also developed using an RNA substrate to verify that RNase B had indeed retained its function after being subjected to the necessary glycan modification conditions. This is the first study that verifies both activity and secondary structure of a glycoprotein after enzymatic glycan trimming for use in biopharmaceutical development methods. The evidence of preserved structure and function for a modified glycoprotein indicates that extracellular enzymatic modification methods could be implemented in producing designer glycoproteins. © 2008 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 98:2581,2591, 2009 [source] The Question of Sustainability for Microfinance Institutions,JOURNAL OF SMALL BUSINESS MANAGEMENT, Issue 1 2007J. Jordan Pollinger Microentrepreneurs have considerable difficulty accessing capital from mainstream financial institutions. One key reason is that the costs of information about the characteristics and risk levels of borrowers are high. Relationship-based financing has been promoted as a potential solution to information asymmetry problems in the distribution of credit to small businesses. In this paper, we seek to better understand the implications for providers of "microfinance" in pursuing such a strategy. We discuss relationship-based financing as practiced by microfinance institutions (MFIs) in the United States, analyze their lending process, and present a model for determining the break-even price of a microcredit product. Comparing the model's results with actual prices offered by existing institutions reveals that credit is generally being offered at a range of subsidized rates to microentrepreneurs. This means that MFIs have to raise additional resources from grants or other funds each year to sustain their operations as few are able to survive on the income generated from their lending and related operations. Such subsidization of credit has implications for the long-term sustainability of institutions serving this market and can help explain why mainstream financial institutions have not directly funded microenterprises. We conclude with a discussion of the role of nonprofit organizations in small business credit markets, the impact of pricing on their potential sustainability and self-sufficiency, and the implications for strategies to better structure the credit market for microbusinesses. [source] Patient Willingness to Pay for a Kidney for TransplantationAMERICAN JOURNAL OF TRANSPLANTATION, Issue 6 2010D. K. Herold While kidney transplantation is the most cost-effective treatment available for end-stage renal disease (ESRD) and affords patients with the best quality of life, the current supply of kidneys does not meet the demand. A potential solution to increasing the supply is to compensate living donors for a kidney. The purpose of this study was to describe ESRD patient willingness to pay for a kidney. Using a self-administered survey, 107 patients in 31 U.S. states completed the survey. The quantitative method and descriptive survey design employed descriptive, correlational, nonparametric and multivariate statistical tests to evaluate the data. Of participants, 78.5% were willing to pay for a kidney; there were significant correlations between gender, health status, household income, preferred source of a kidney and willingness to pay. Men, patients with poor and fair health status and those with household incomes ,$50 000 were more willing to pay. Step-wise regression analysis found price and doctor's influence accounting for 52% of variance in willingness to pay. As price increased and doctor's opinion mattered, willingness to pay increased. This study supports development of additional studies with larger sample sizes and patients on kidney transplant waiting lists. [source] Reproduction, early development and larviculture of the barber goby, Elacatinus figaro (Sazima, Moura & Rosa 1997)AQUACULTURE RESEARCH, Issue 1 2009Maria Eugenia Meirelles Abstract The barber goby, Elacatinus figaro, is a cleaner species of ecological importance and of keen interest to the aquarium trade. Endemic to Brazil, it is a threatened species and so aquaculture is a potential solution for reducing pressure on the natural stocks. This study describes the reproductive behaviour, the embryonic and larval development and the general breeding and rearing conditions. Ten wild fish initiated the formation of breeding pairs 20 days after acclimation to captivity. Spawning started 12 days after the first pair was formed, with one female from each pair spawning from 140 to 700 eggs (n=15 spawnings). The average period of incubation of the eggs was 6.8 days at 25 °C. The best hatching rate was 99.5% (n=10 spawnings). Larval rearing used Nannochloropsis oculata with rotifers (Brachionus rotundiformis) as the first food (day 0,25); nauplii and meta-nauplii of Artemia were fed from day 18 until larval metamorphosis with subsequent weaning using commercial marine fish diets. The transformation to juveniles started at around the 30th day post hatch. The best larval survival rate until complete metamorphosis was 30.6% (n=4 larvicultures). After this period, the mortality was insignificant. This study demonstrated that the cultivation of barber goby is feasible. [source] Higher taxa are effective surrogates for species in the selection of conservation reserves in estuariesAQUATIC CONSERVATION: MARINE AND FRESHWATER ECOSYSTEMS, Issue 6 2009Mohammad Reza Shokri Abstract 1.The lack of information about marine biodiversity is problematic for the selection of conservation reserves that aim to protect representative samples of biodiversity. A number of surrogate measures for biodiversity have been suggested as a potential solution to this problem. 2.The present study tested the effectiveness of using higher taxa of macroinvertebrates as a surrogate for species-level identification to depict spatial variation in species richness and assemblage variation and to select conservation reserves in one estuary in south-east Australia. 3.Spatial patterns of richness and assemblage variation for species were significantly correlated with patterns defined from genera, families, orders, classes, and phyla with a decline in the magnitude of correlation coefficients from finer to coarser resolutions. A network of reserves selected to include representatives of all phyla, classes, orders, families and genera coincidentally included 54%, 61.7%, 75%, 92.6%, 98.8% species in 8.3%, 13.9%, 17.7%, 44.4% and 58.3% of grid cells, respectively. However, only reserves selected for genera, families and orders performed significantly better than random selection. 4.Percentage of species represented by orders, families and genera in a realistic level of available grid cells for conservation (i.e. 13.9%) were very close ranging between 70 and 73.5%. A factor diminishing the performance of order as surrogate for species richness was related to the difficulty of identifying many macroinvertebrates to the order level. Therefore, it is concluded that genus- and family-level identification is an effective surrogate for species-level identification for conservation planning in estuaries. Copyright © 2008 John Wiley & Sons, Ltd. [source] PPPs in Health: Static or Dynamic?AUSTRALIAN JOURNAL OF PUBLIC ADMINISTRATION, Issue 2010Anneloes Blanken Public-Private Partnerships (PPPs), or in the Private Finance Initiative (PFI) form throughout the Anglo-Saxon world, are gaining in popularity for the provision of hospitals. Increasingly common around the world and seen as a potential solution that will both overcome the bottlenecks associated with more conventional approaches to hospital provision and generate ,value for money'(VfM), these PFI-PPPs represent a major, but so far under-evaluated, concept. This article analyses whether public-private partnerships do deliver the benefits claimed. It endeavors to assess the potential of hospital PFI-PPPs, and their empirical performance on achieving VfM, through addressing the way the contractual arrangements are structured and the extent of flexibility they generate. Initial lessons arising from the current provisioning of English and Australian hospital facilities by PFI-PPPs are identified so they can be taken into consideration in future projects. [source] Cloning large natural product gene clusters from the environment: Piecing environmental DNA gene clusters back together with TARBIOPOLYMERS, Issue 9 2010Jeffrey H. Kim Abstract A single gram of soil can contain thousands of unique bacterial species, of which only a small fraction is regularly cultured in the laboratory. Although the fermentation of cultured microorganisms has provided access to numerous bioactive secondary metabolites, with these same methods it is not possible to characterize the natural products encoded by the uncultured majority. The heterologous expression of biosynthetic gene clusters cloned from DNA extracted directly from environmental samples (eDNA) has the potential to provide access to the chemical diversity encoded in the genomes of uncultured bacteria. One of the challenges facing this approach has been that many natural product biosynthetic gene clusters are too large to be readily captured on a single fragment of cloned eDNA. The reassembly of large eDNA-derived natural product gene clusters from collections of smaller overlapping clones represents one potential solution to this problem. Unfortunately, traditional methods for the assembly of large DNA sequences from multiple overlapping clones can be technically challenging. Here we present a general experimental framework that permits the recovery of large natural product biosynthetic gene clusters on overlapping soil-derived eDNA cosmid clones and the reassembly of these large gene clusters using transformation-associated recombination (TAR) in Saccharomyces cerevisiae. The development of practical methods for the rapid assembly of biosynthetic gene clusters from collections of overlapping eDNA clones is an important step toward being able to functionally study larger natural product gene clusters from uncultured bacteria. © 2010 Wiley Periodicals, Inc. Biopolymers 93: 833,844, 2010. [source] Abductive Diagnosis Using Time-Objects: Criteria for the Evaluation of SolutionsCOMPUTATIONAL INTELLIGENCE, Issue 1 2001Elpida T. Keravnou Diagnostic problem solving aims to account for, or explain, a malfunction of a system (human or other). Any plausible potential diagnostic solution must satisfy some minimum criteria relevant to the application. Often there will be several plausible solutions, and further criteria will be required to select the "best" explanation. Expert diagnosticians may employ different, complex criteria at different stages of their reasoning. These criteria may be combinations of some more primitive criteria, which therefore should be represented separately and explicitly to permit their flexible and transparent combined usage. In diagnostic reasoning there is a tight coupling between the formation of potential solutions and their evaluation. This is the essence of abductive reasoning. This article presents an abductive framework for diagnostic problem solving. Time-objects, an association of a property and an existence, are used as the representation formalism and a number of primitive, general evaluation criteria into which time has been integrated are defined. Each criterion provides an intuitive yardstick for evaluating the space of potential solutions. The criteria can be combined as appropriate for particular applications to define plausible and best explanations. The central principle is that when time is diagnostically significant, it should be modeled explicitly to enable a more accurate formulation and evaluation of diagnostic solutions. The integration of time and primitive evaluation criteria is illustrated through the Skeletal Dysplasias Diagnostician (SDD) system, a diagnostic expert system for a real-life medical domain. SDD's notions of plausible and best explanation are reviewed so as to show the difficulties in formalizing such notions. Although we illustrate our work by medical problems, it has been motivated by consideration of problems in a number of other domains (fermentation monitoring, air and ground traffic control, power distribution) and is intended to be of wide applicability. [source] A Consideration of Museum Education Collections: Theory and ApplicationCURATOR THE MUSEUM JOURNAL, Issue 2 2001Shane J. Macfarlan Museum education collections are used to provide visitors with opportunities to handle museum objects. These collections are primarily composed of objects that are damaged, lack provenance, or do not fit the scope of the collection. Sometimes, these collections are displayed haphazardly and their interpretation may lack thematic context. Some museum education collections are not being utilized to their fullest educational capacity. The application of cognitive, exhibition, and collections management theories can alleviate some problems with museum education collections. A critique of the education collection at the Lubbock Lake Landmark is presented as a case study of these problems and some of the potential solutions to them. The study can be used as a template by other museums to solve similar problems in their education collections. [source] Classifying ecological communities and synthesizing data for natural resource management: Some problems and potential solutionsECOLOGICAL MANAGEMENT & RESTORATION, Issue 2 2008John Benson No abstract is available for this article. [source] Development of a biological control-based Integrated Pest Management method for Bemisia tabaci for protected sweet pepper cropsENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, Issue 1 2009F. J. Calvo Abstract The tobacco whitefly, Bemisia tabaci Gennadius (Hemiptera: Aleyrodidae), is a key pest in commercial sweet pepper crops in southeast Spain. Its biological control is currently based on augmentative introductions of the parasitic wasp Eretmocerus mundus Mercet (Hymenoptera: Aphelinidae), which need to be occasionally supplemented with pesticide applications. These pesticides can be harmful for the biological control agents. Therefore, it is important to improve the current strategy by reducing dependency on pesticides. Two potential solutions are conceivable: addition of another effective biocontrol agent or application of pesticide prior to the release of biocontrol agents. The mirid bug Nesidiocoris tenuis Reuter (Heteroptera: Miridae) and the predatory mite Amblyseius swirskii Athias-Henriot (Acari: Phytoseiidae) are promising candidates as additional biocontrol agents. The aim of the present study was to test these possible solutions in two subsequent trials, i.e., a ,selection' and an ,improvement' experiment. In the selection experiment, four treatments were compared: E. mundus, N. tenuis + E. mundus, A. swirskii + E. mundus, and A. swirskii + N. tenuis + E. mundus. Amblyseius swirskii appeared able to significantly increase effectiveness against the pest, in contrast to N. tenuis, which did not contribute to whitefly control. The best strategy was the combination of E. mundus and A. swirskii. In the improvement experiment, three treatments were compared: E. mundus, A. swirskii + E. mundus, and A. swirskii + E. mundus + pesticides. Amblyseius swirskii again proved capable of significantly reducing whitefly populations, and the implementation of pesticides before the release of the biocontrol agents was shown to increase the effectiveness against the pest even more. [source] Optimal Thermal Unit Commitment Integrated with Renewable Energy Sources Using Advanced Particle Swarm OptimizationIEEJ TRANSACTIONS ON ELECTRICAL AND ELECTRONIC ENGINEERING, Issue 5 2009Shantanu Chakraborty Student member Abstract This paper presents a methodology for solving generation planning problem for thermal units integrated with wind and solar energy systems. The renewable energy sources are included in this model due to their low electricity cost and positive effect on environment. The generation planning problem also known by unit commitment problem is solved by a genetic algorithm operated improved binary particle swarm optimization (PSO) algorithm. Unlike trivial PSO, this algorithm runs the refinement process through the solutions within multiple populations. Some genetic algorithm operators such as crossover, elitism, and mutation are stochastically applied within the higher potential solutions to generate new solutions for next population. The PSO includes a new variable for updating velocity in accordance with population best along with conventional particle best and global best. The algorithm performs effectively in various sized thermal power system with equivalent solar and wind energy system and is able to produce high quality (minimized production cost) solutions. The solution model is also beneficial for reconstructed deregulated power system. The simulation results show the effectiveness of this algorithm by comparing the outcome with several established methods. Copyright © 2009 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. [source] Environmental and sustainability aspects of hydrogen and fuel cell systemsINTERNATIONAL JOURNAL OF ENERGY RESEARCH, Issue 1 2007Ibrahim DincerArticle first published online: 1 AUG 200 Abstract Discussed in this paper are current environmental problems, potential solutions to these problems, possible future hydrogen energy-utilization patterns for better environment and sustainable development through life cycle assessment (LCA), and how the principles of thermodynamics via exergy can be beneficially used to evaluate hydrogen and fuel cell systems and their role in sustainable development. Throughout the paper current and future perspectives of hydrogen and fuel cell systems based on exergetic, LCA and sustainability aspects development are considered. The results will likely be useful to scientists, researchers and engineers as well as policy and decision makers. Two case studies on the LCA aspects of hydrogen and fuel cell systems are presented to highlight the importance of the hydrogen and fuel cell systems and show that these can help achieve better environment and sustainability. Copyright © 2006 John Wiley & Sons, Ltd. [source] An Integer Linear Programming Problem with Multi-Criteria and Multi-Constraint Levels: a Branch-and-Partition AlgorithmINTERNATIONAL TRANSACTIONS IN OPERATIONAL RESEARCH, Issue 5 2001Jun Li In this paper, we propose a branch-and-partition algorithm to solve the integer linear programming problem with multi-criteria and multi-constraint levels (MC-ILP). The procedure begins with the relaxation problem that is formed by ignoring the integer restrictions. In this branch-and-partition procedure, an MC linear programming problem is adopted by adding a restriction according to a basic decision variable that is not integer. Then the MC-simplex method is applied to locate the set of all potential solutions over possible changes of the objective coefficient parameter and the constraint parameter for a regular MC linear programming problem. We use parameter partition to divide the (,, ,) space for integer solutions of MC problem. The branch-and-partition procedure terminates when every potential basis for the relaxation problem is a potential basis for the MC-ILP problem. A numerical example is used to demonstrate the proposed algorithm in solving the MC-ILP problems. The comparison study and discussion on the applicability of the proposed method are also provided. [source] Vacuum-assisted closure home care training: a process to link education to improved patient outcomesINTERNATIONAL WOUND JOURNAL, Issue 2008Kevin Y Woo Negative pressure wound therapy (NPWT) applies subatmospheric pressure across the wound bed inducing cellular and molecular changes that are beneficial to wound healing. This healing modality may facilitate tissue debridement, infection/inflammation control, and moisture balance; the key components of the wound bed preparation paradigm. To ensure that scientific evidence is diffused into daily clinical practice, we are proposing a knowledge transfer model that articulates an educational plan for the various levels of professional development. The discussion highlights the challenges and potential solutions to integrate NPWT into a seamless continuum of care including a community-based patient care model. [source] Interview with a Quality Leader: Dr. Ashish JhaJOURNAL FOR HEALTHCARE QUALITY, Issue 5 2010Kevin C. Park Abstract: Dr. Jha is an Associate Professor of Medicine at Harvard Medical School. The major themes of his research are: 1. Quality of care provided by healthcare systems, with a focus on healthcare disparities as a marker of poor care. 2. Information technology among other tools as potential solutions for reducing medical errors and disparities while improving overall quality. 3. Organizations that provide care for minorities and underserved populations and the role clinical information systems can play in improving their care. [source] Cognitive therapy for performance anxietyJOURNAL OF CLINICAL PSYCHOLOGY, Issue 8 2004Thomas L. Rodebaugh We present and illustrate the major components of cognitive therapy for performance anxiety, focusing on the performance fears of a client treated with a protocol designed for social phobia. The basic supposition of cognitive theory is that a client's thoughts and beliefs about situations maintain distressing feelings, such as anxiety. Changing these beliefs involves detection and disputation of anxiety-provoking thoughts, as well as testing of these thoughts through exposure to feared situations. Through a process of identifying existing beliefs about performance situations and challenging these beliefs, clients can gain a more realistic and less anxiety-producing perspective on performance tasks. Specific techniques, along with common difficulties and potential solutions, are presented in a detailed case study. © 2004 Wiley Periodicals, Inc. J Clin Psychol/In Session. [source] | |||||||||||||||||||||||||||||||||||||||||||