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Potential Challenges (potential + challenge)
Selected AbstractsAutomobile Reliance Among the Elderly: Race and Spatial Context EffectsGROWTH AND CHANGE, Issue 2 2003Brigitte Waldorf To meet their mobility needs, the elderly assign pivotal importance to the automobile despite the potential challenge of driving cessation and searching for alternatives to automobile transportation. Older persons' generally strong reliance on the automobile varies, however, by land use patterns (density) as well as by demographic and socioeconomic characteristics. This paper analyzes the effects of spatial context and personal attributes on automobile reliance among the elderly. Using the 1995 Nationwide Personal Transportation Survey (NPTS) trip data, two models of automobile reliance among elderly (65+) trip makers are estimated. The results show that spatial context effects of automobile reliance vary by demographic characteristics; in particular, they are more pronounced for black than for white elderly. Moreover, race variation in automobile reliance is strongest in urban locations rather than less dense spatial contexts. Finally, the differentiation between being a passenger rather than a driver is salient in order to understand locational and racial variations in automobile reliance among the elderly. [source] ETHICAL PROBLEMS IN CONDUCTING RESEARCH IN ACUTE EPIDEMICS: THE PFIZER MENINGITIS STUDY IN NIGERIA AS AN ILLUSTRATIONDEVELOPING WORLD BIOETHICS, Issue 1 2010EMMANUEL R. EZEOME ABSTRACT The ethics of conducting research in epidemic situations have yet to account fully for differences in the proportion and acuteness of epidemics, among other factors. While epidemics most often arise from infectious diseases, not all infectious diseases are of epidemic proportions, and not all epidemics occur acutely. These and other variations constrain the generalization of ethical decision-making and impose ethical demands on the individual researcher in a way not previously highlighted. This paper discusses a number of such constraints and impositions. It applies the ethical principles enunciated by Emmanuel et al.1 to the controversial Pfizer study in Nigeria in order to highlight the particular ethical concerns of acute epidemic research, and suggest ways of meeting such challenges. The paper recommends that research during epidemics should be partly evaluated on its own merits in order to determine its ethical appropriateness to the specific situation. Snap decisions to conduct research during acute epidemics should be resisted. Community engagement, public notification and good information management are needed to promote the ethics of conducting research during acute epidemics. Individual consent is most at risk of being compromised, and every effort should be made to ensure that it is maintained and valid. Use of data safety management boards should be routine. Acute epidemics also present opportunities to enhance the social value of research and maximize its benefits to communities. Ethical research is possible in acute epidemics, if the potential challenges are thought of ahead of time and appropriate precautions taken. [source] The capacity of Australian ED to absorb the projected increase in intern numbersEMERGENCY MEDICINE AUSTRALASIA, Issue 2 2010Anthony Chong Abstract As a reaction to the medical workforce shortage in Australia, a large expansion of undergraduate medical education has occurred through the provision of funding of additional medical student places. As a consequence, the number of medical graduates is anticipated to increase by as much as 90% with a peak in numbers anticipated in 2012. With ED already under pressure, this increase has serious implications for ED, particularly the delivery of intern and student teaching. This integrated review describes potential challenges that might arise from the predicted increase in intern numbers working in ED. A structured literature search was conducted from which 44 directly relevant articles were identified. We discuss the possible impact of an increased number of medical graduates on emergency medical staff, education, supervision and feedback to interns, and given the potential impacts on the education of junior doctors; we review the purpose and implementation of the Australian Curriculum framework for Junior Doctors in relation to their learning requirements. Although there is consensus by most postgraduate bodies that the core emergency term in emergency medicine should be retained, the impact of increased intern numbers might dramatically affect the clinical experiences, supervision and educational resources in the ED. This might necessitate cultural changes in medical education and ED function. [source] The alcohol industry and trade agreements: a preliminary assessmentADDICTION, Issue 2009Donald W. Zeigler ABSTRACT Aims To review trade agreements, their relation to alcohol control policy and examine the role of the alcohol industry in supporting and attempting to influence trade policy. Methods Review of peer review, public health advocacy literature (both pro and con on free trade), business, press and government documents on trade agreements, assess current and potential challenges by trade agreements to alcohol control policy and investigate the means and extent of industry influence in trade agreements. Findings ,Free' trade agreements reduce trade barriers, increase competition, lower prices and promote alcohol consumption. However, international treaties, negotiated by free trade experts in close consultation with corporate lobbyists and without significant, if any, public health input, governments and corporations contain significant provisions that will result in increased alcohol consumption and may challenge public health measures of other nations as constraints on trade. Conversely, alcohol control measures seek to reduce access and consumption, raise prices and restrict advertising and product promotion. The prospect is for increased alcohol consumption and concomitant problems throughout the world. Conclusions Trade agreements challenge effective alcohol control policies. The alcohol industry seeks to influence agreements and can be expected to work through trade agreements to reduce tariffs, increase market access and seek to restrict effective domestic regulations. Further research is needed on the impact of trade agreements and the ongoing role of the industry. Advocates must recognize the inherent conflicts between unbridled free trade and public health, work to exclude alcohol from trade agreements, counter industry influence and protect alcohol control policies. [source] Operating room nurses' perceptions of the effects of physician-perpetrated abuseINTERNATIONAL NURSING REVIEW, Issue 3 2010B.L. Higgins rn HIGGINS B.L. & MACINTOSH J. (2010) Operating room nurses' perceptions of the effects of physician-perpetrated abuse. International Nursing Review57, 321,327 Background:, Operating room (OR) nurses experience abuse perpetrated by physicians; however, little research has been conducted to examine nurses' perceptions of the effects of such abuse. Aims:, The aim of this research was to understand participants' perceptions of physician-perpetrated abuse on their health and ability to provide patient care. Materials/Methods:, In this qualitative descriptive study, ten operating room nurses working in Eastern Canada participated in open-ended, individual audiotaped interviews that were transcribed for analysis using Boyatzis' method for code development. Results:, Three categories of factors contributing to abuse were developed. The first, culture of the OR, included environment and hierarchy. The second, catalysts of abuse, included nurses' positions and experience as well as non-nurse factors such as resources and interpersonal relationships among physicians. The third category, perceived effects, included psychological, physical and social health consequences for nurses. Effects on patient care consisted of safety and potential challenges to access. Discussion:, Nursing practice implications included mentoring, support and accountability for action. Educational implications related to interdisciplinary education and increased education on communication, assertiveness, and awareness of abuse. Implications for research included studying perceptions of other health-care providers including physicians, studying recruitment and retention in relation to abuse, and studying other abuse in health care such as horizontal violence. Conclusion:, We suggest a proactive approach for empowering OR nurses to address abuse and an increased focus on interdisciplinary roles. [source] Manipulating Processing Difficulty of Reading Comprehension Questions: The Feasibility of Verbal Item GenerationJOURNAL OF EDUCATIONAL MEASUREMENT, Issue 4 2005Joanna S. Gorin Based on a previously validated cognitive processing model of reading comprehension, this study experimentally examines potential generative components of text-based multiple-choice reading comprehension test questions. Previous research (Embretson & Wetzel, 1987; Gorin & Embretson, 2005; Sheehan & Ginther, 2001) shows text encoding and decision processes account for significant proportions of variance in item difficulties. In the current study, Linear Logistic Latent Trait Model (LLTM; Fischer, 1973) parameter estimates of experimentally manipulated items are examined to further verify the impact of encoding and decision processes on item difficulty. Results show that manipulation of some passage features, such as increased use of negative wording, significantly increases item difficulty in some cases, whereas others, such as altering the order of information presentation in a passage, did not significantly affect item difficulty, but did affect reaction time. These results suggest that reliable changes in difficulty and response time through algorithmic manipulation of certain task features is feasible. However, non-significant results for several manipulations highlight potential challenges to item generation in establishing direct links between theoretically relevant item features and individual item processing. Further examination of these relationships will be informative to item writers as well as test developers interested in the feasibility of item generation as an assessment tool. [source] Endothelial Progenitor Cells: A Promising Therapeutic Alternative for Cardiovascular DiseaseJOURNAL OF INTERVENTIONAL CARDIOLOGY, Issue 2 2007CHUNMING DONG The integrity and functional activity of the endothelial monolayer play a critical role in preventing atherosclerotic disease progression. Endothelial cell (EC) damage by atherosclerosis risk factors can result in EC apoptosis with loss of the integrity of the endothelium. Thus, approaches to repair the injured vessels with the goal of regenerating ECs have been tested in preclinical experimental models and in clinical studies. Indeed, endothelial progenitor cells (EPCs) originating from the bone marrow have been shown to incorporate into sites of neovascularization and home to sites of endothelial denudation. These cells may provide an endogenous repair mechanism to counteract ongoing risk factor-induced endothelial injury and to replace dysfunctional endothelium. Risk factors for coronary artery disease, such as age, smoking, hypertension, hyperlipidemia, and diabetes, however, reduce the number and functional activity of circulating EPCs, potentially restricting the therapeutic prospective of progenitor cells and limiting the regenerative capacity. Furthermore, the impairment of EPCs by risk factors may contribute to atherogenesis and atherosclerotic disease progression. The article reviews the role of EPCs in atherogenesis and in predicting cardiovascular outcomes, and highlights the potential challenges in developing therapeutic strategies aiming to interfere with the balance of injury and repair mechanisms. [source] PANNING FOR GOLD: A CLINICIAN's GUIDE TO USING RESEARCHJOURNAL OF MARITAL AND FAMILY THERAPY, Issue 1 2006Lee M. Williams The gap between research and clinical practice is one of the key challenges facing family therapy. Clinicians often fail to incorporate research findings into their practice because they do not know how to search, evaluate, or apply research to their clinical work. The purpose of this article is to help clinicians become better consumers of research. This article explores the potential value of research to clinicians, as well as negative beliefs that clinicians may have about research. The article also describes how clinicians can use research to inform their clinical work, as well as potential challenges that can be encountered. [source] Quantification and characterization of subvisible proteinaceous particles in opalescent mAb Formulations Using Micro-Flow ImagingJOURNAL OF PHARMACEUTICAL SCIENCES, Issue 6 2010Deepak K. Sharma Abstract Micro-flow imaging (MFIÔ) has been shown to be more sensitive than light obscuration (LO) methods for measuring subvisible proteinaceous particles in protein formulations. Given the potential challenges in detecting particulates in opalescent mAb formulations, the accuracy of MFI to size and count particles in opalescent solutions was investigated and compared to LO and membrane microscopy methods. Proteinaceous monoclonal antibody (mAb) particles, generated either by chemical denaturation or agitation stress, polystyrene and glass particles were used as model systems for measurements in opalescent mAb solutions. The sizing and counting accuracies of MFI were unaffected by the opalescence of the medium. Using glass particles as a model system for proteinaceous particles, MFI was able to detect relatively low particle concentrations (,10/mL) in opalescent solutions. MFI showed excellent linearity (R2,=,0.9969) for quantifying proteinaceous particles in opalescent solutions over a wide range of particle concentrations (,20,160,000/mL). Analyses of MFI particle image intensities revealed significant differences in the transparency of proteinaceous particles as a function of their size and mode of generation. LO method significantly underestimated proteinaceous particles, particularly those in the 2,10,µm size range. The less opaque proteinaceous particles were relatively more underestimated by the LO method in opalescent solutions. © 2010 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 99: 2628,2642, 2010 [source] Lawyer Specialization,Managing the Professional ParadoxLAW & POLICY, Issue 2 2010RICHARD MOORHEAD This article explores a series of paradoxes exposed by specialization within the legal profession. It will argue that while the existing literature rightly identifies specialization as posing potential challenges to coherence, legitimacy, and professional ethics, it fails to grapple with the relationship between professional competence and specialization. In exploring this relationship, three paradoxes are articulated. The first is that specialization is both a necessary element in the development of professionalism and a threat to it. The second is the normative ambiguity of specialization: specialization is capable of giving rise to both benefits and detriments. The third paradox is the profession's response to this ambiguity. It will be argued that the profession's approach is incoherent in public interest terms and can be best explained as part of a desire to protect its members' interests and its collective identity over the public interest in competence. These arguments are made in the context of a series of three empirical studies of specialists and nonspecialists in legal aid practice in England and Wales. The evidence is worrying enough to suggest significant concerns about the quality and indeed legitimacy of the professional qualification as a general warrant of competence. The implications for institutionalizing specialization within the legal profession are discussed. [source] Variation in part-time job quality within the nonprofit human service sectorNONPROFIT MANAGEMENT & LEADERSHIP, Issue 4 2009Anna Haley-Lock This article extends the growing literature on the quality of part-time employment to the domain of nonprofit human services, specifically grassroots organizations in which paid work is itself a relatively new reality. It addresses three central questions: How do part-time and full-time workers differ in their personal and household characteristics? How do part-time jobs differ in access to employment benefits from their full-time counterparts; and finally, How does benefits access vary among part-time job titles? These lines of inquiry are examined using data from the populations of nonprofit domestic violence programs and their employees in a large midwestern metropolitan area. Analyses of worker-level data reveal that part-time workers in these settings disproportionately live with children, are in committed relationships, and report a strong preference for employment that facilitates work-life balance; they are also less likely to be primary household wage earners. Analyses at the level of jobs suggest that employment benefits extended to part-time jobs are minimal compared to their full-time equivalents, but there are also striking variations among different part-time titles. The results offer insights into the nature of part-time work in these nonprofit human service settings and potential challenges for effective management. [source] Seeking red herrings in the wood: tending the shared spaces of environmental and feminist geographiesTHE CANADIAN GEOGRAPHER/LE GEOGRAPHE CANADIEN, Issue 1 2007MAUREEN G. REED In this article I argue the need for feminist and environmental geographers to work more diligently to find, mind and tend the intersections of their research agendas to enrich scholarship and deepen impacts on public policy. Such a project requires us to move beyond an obvious call to acknowledge one another's work and towards the boundaries of our respective fields in order to co-create ,boundary objects' that provide opportunities for mutual exchange, collaboration and learning. Rather than being ,red herrings' or diversions from our main research foci, boundary objects bring new insights to taken-for-granted concepts. I focus on one example to argue that social sustainability of rural places is better understood by an integrated understanding of what constitutes a ,worker' in a forestry community. A redefinition of the worker that draws on insights and interests from both environmental and feminist geographers reveals an underlying gender bias in environmental decision-making processes and illustrates how the concept of social sustainability has been artificially restricted in practice. Nevertheless, collaborations are never easy. I draw attention to potential challenges of such collaborations that include the need to establish mutually agreeable protocols, joint commitment to constructive, respectful debate and strategies to ensure that research provides meaningful contributions to theory and public policy. Dans cet article, je vais tenter de montrer que les géographes féministes et les géographes de l'environnement auront à travailler avec plus d'acharnement pour reconnaître, étudier et entretenir les points communs de leurs agendas de recherche en vue d'augmenter la valeur scientifique des études et d'accroître les retombées sur les politiques publiques. Un tel projet exige que nous puissions dépasser le stade de la reconnaissance de nos travaux et se tourner ainsi vers les frontières de nos disciplines afin de co-créer des ,objets frontaliers' qui offrent des possibilités d'échanges d'idées, de collaboration et d'apprentissage. Plutôt qu'être des ,fausses pistes' ou des déviations de nos principaux thèmes de recherche, ces objets frontaliers pourraient apporter un éclairage nouveau sur des concepts tenus pour acquis. À l'aide d'un exemple, j'avance que pour mieux comprendre la durabilité sociale en milieux ruraux, il faut acquérir une compréhension intégrée de l'ensemble des dimensions d'un ,ouvrier' membre d'une communauté forestière. L'ouvrier est redéfini en mettant à contribution les connaissances et intérêts des géographes environnementaux et féministes. Cette définition met au jour un parti pris fondé sur le sexe dans les processus décisionnels en matière d'environnement et démontre de quelle façon le concept de la durabilité sociale s'en trouve artificiellement restreint dans la pratique. Les collaborations ne sont cependant jamais faciles àétablir. J'attire l'attention sur les difficultés potentielles de ces collaborations concernant notamment la mise en place de protocoles acceptables pour les deux parties, la promesse de tenir des débats constructifs et respectueux, et les stratégies visant à garantir que la recherche participe de manière vitale autant au développement de la théorie que des politiques publiques. [source] Claude Lévi-Strauss (1908,2009): The apotheosis of heroic anthropology (Respond to this article at http://www.therai.org.uk/at/debate)ANTHROPOLOGY TODAY, Issue 5 2010Albert Doja Claude Lévi-Strauss is one of the greatest interdisciplinary writers of the twentieth century whose influence extends far beyond his own discipline of social anthropology. His inquiry illuminates the borderlands between ,primitive' and non-primitive, self and other, myth and history, human and animal, art and nature, and the dichotomies that give structure to culture, society, history and agency. This commemorative article of his legacy assesses disciplinary and interdisciplinary debates influenced by Levi-Strauss's inquiry and methods, and looks at potential challenges for the future. Lévi-Strauss's ideas continue to be influential in our assessments of what we mean by culture, values, social organization, including social transformations and cultural ideologies such as ethnocentrism, nationalism, fundamentalism, pluralism, neo-liberalism, post-modernism, relativism, humanism and universalism. [source] | |||||||||||||