Home About us Contact
|
Home About us Contact | ||
|
|
||
Asymmetric Hydrogenation (asymmetric + hydrogenation)
Kinds of Asymmetric Hydrogenation Terms modified by Asymmetric Hydrogenation Selected AbstractsSupported Chiral Monodentate Ligands in Rhodium-Catalysed Asymmetric Hydrogenation and Palladium-Catalysed Asymmetric Allylic AlkylationEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 33 2009Bert H. G. Swennenhuis Abstract A family of monodentate polystyrene-supported phosphites, phosphoramidites and phosphanes has been prepared and evaluated as ligands in rhodium-catalysed asymmetric hydrogenation and palladium-catalysed asymmetric allylic alkylation. The supported ligands yielded active and enantioselective catalysts, which in selected cases match the performance of the nonsupported counterparts. As expected, the performance of the supported ligands in the rhodium-catalysed hydrogenation depends on the nature of the ligand, the type of polymeric support, as well as on the substrate. Additionally, the supported ligands have been applied in the monodentate ligand combination approach, by combining them with nonsupported monodentate ligands. The partially supported heteroligand combinations possess different catalytic properties than the related nonsupported combinations. The heteroligand species, however, are not formed selectively, and nonsupported homoleptic complexes also contribute to the overall activity. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source] Repetitive Application of a Fluorous Chiral BINAP,Ru Complex in the Asymmetric Hydrogenation of OlefinsEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 13 2007Joachim Horn Abstract A trisperfluoroalkylsilyl-modified (S)-BINAP ligand has been prepared and its pertinent Ru complex applied to the asymmetric hydrogenation of olefins. Efficient separation of the Ru catalyst by filtration and its reuse was achieved. Relative to the untagged complex with a Ru-leaching of 300 ppm, leaching into the product was low (1.6,4.9 ppm). (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source] Iridium-Difluorphos-Catalyzed Asymmetric Hydrogenation of 2-Alkyl- and 2-Aryl-Substituted Quinoxalines: A General and Efficient Route into TetrahydroquinoxalinesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2010Damien Cartigny Abstract A highly efficient and general iridium-difluorphos-catalyzed asymmetric hydrogenation of diverse 2-alkyl- and 2-aryl-substituted quinoxalines into biologically and pharmaceutically relevant 2-substituted-1,2,3,4-tetrahydroquinoxaline units has been developed. High isolated yields and excellent enantioselectivities of up to 95% for 2-alkyl-substituted quinoxalines and of up to 94% for 2-aryl-substituted quinoxalines were obtained. [source] Chirally Modified Platinum Nanoparticles Stabilized by Dendritic Core-Multishell Architectures for the Asymmetric Hydrogenation of Ethyl PyruvateADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2010Juliane Keilitz Abstract In this paper we present the asymmetric hydrogenation of ,-keto esters with platinum nanoparticles homogeneously stabilized in dendritic core-multishell architectures. The main focus lies on recycling and metal leaching, because little is reported so far about these aspects. It is shown that the stabilizing polymer allows for the efficient modification of the Pt surface with the chiral alkaloid cinchonidine, thereby inducing enantioselectivity and enhancing the reaction rate in the asymmetric hydrogenation of ethyl pyruvate. After optimization of the reaction conditions 63% ee for (R)-ethyl lactate was obtained. During recycling it was found that this value could even be increased upon ultrafiltration of the catalyst prior to use. Recycling was accomplished for 10,cycles with stable activity and enantioselectivity (,73% ee) in the first eight runs. Aggregation of the initially well dispersed nanoparticles was observed by transmission electron microscope (TEM) analysis, leading to reduced conversion after the 8th cycle, but metal leaching into the product has been observed only in the very first run. [source] A General Approach to the Synthesis of ,2 -Amino Acid Derivatives via Highly Efficient Catalytic Asymmetric Hydrogenation of ,-AminomethylacrylatesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2010Yujuan Guo Abstract A new strategy was developed for the synthesis of a valuable class of ,-aminomethylacrylates via the Baylis,Hillman reaction of different aldehydes with methyl acrylate followed by acetylation of the resulting allylic alcohols and SN2,-type amination of the allylic acetates. Asymmetric hydrogenation of these diverse olefinic precursors using rhodium(Et-Duphos) catalysts provided the corresponding ,2 -amino acid derivatives with excellent enantioselectivities and exceedingly high reactivities (up to >99.5% ee and S/C=10,000). The first hydrogenation of (Z)-configurated substrates was studied for the synthesis of ,2 -amino acid derivatives. The high influence of the substrate geometry and steric hindrance on the reactivity and enantioselectivity was also disclosed for this reaction. This protocol provides a highly practical, facile and scalable method for the preparation of optically pure ,2 -amino acids and their derivatives under mild reaction conditions. [source] Highly Efficient and Enantioselective Iridium-Catalyzed Asymmetric Hydrogenation of N -AryliminesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 18 2009Wei Li Abstract A catalytic method employing the cationic iridium-(Sc,Rp)-DuanPhos [(1R,1,R,2S,2,S)-2,2,-di- tert -butyl-2,2,,3,3, -tetrahydro-1H,1,H -1,1,-biisophosphindole] complex and BARF {tetrakis[3,5-bis(trifluoromethyl)phenyl]borate} counterion effectively catalyzes the enantioselective hydrogenation of acyclic N -arylimines with high turnover numbers (up to 10,000 TON) and excellent enantioselectivities (up to 98% ee), achieving the practical synthesis of chiral secondary amines. [source] Enantioselective Synthesis of Chiral Tetrahydroisoquinolines by Iridium-Catalyzed Asymmetric Hydrogenation of EnaminesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 18 2009Pu-Cha Yan Abstract Chiral iridium complexes based on spiro phosphoramidite ligands are demonstrated to be highly efficient catalysts for the asymmetric hydrogenation of unfunctionalized enamines with an exocyclic double bond. In combination with excess iodine or potassium iodide and under hydrogen pressure, the complex Ir/(Sa,R,R)- 3a provides chiral N -alkyltetrahydroisoquinolines in high yields with up to 98% ee. The L/Ir ratio of 2:1 is crucial for obtaining a high reaction rate and enantioselectivity. A deuterium labeling experiment showed that an inverse isotope effect exists in this reaction. A possible catalytic cycle including an iridium(III) species bearing two monophosphoramidite ligands is also proposed. [source] Asymmetric Hydrogenation of Quinoxalines Catalyzed by Iridium/PipPhosADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 16 2009Abstract A catalyst made in situ from the (cyclooctadiene)iridium chloride dimer, [Ir(COD)Cl]2, and the monodentate phosphoramidite ligand (S)-PipPhos was used in the enantioselective hydrogenation of 2- and 2,6-substituted quinoxalines. In the presence of piperidine hydrochloride as additive full conversions and enantioselectivities of up to 96% are obtained. [source] Asymmetric Hydrogenation of ,,,-Unsaturated Ester- PhosphonatesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2009Yange Huang Abstract The rhodium-catalyzed asymmetric hydrogenation of readily available ,,,-unsaturated ester-phosphonates affords the corresponding ,-chiral phosphonates in excellent yield and ee. The resulting products are useful multifunctional building blocks applied in the synthesis of physiologically active compounds. [source] Iridium-Catalysed Asymmetric Hydrogenation of Enamides in the Presence of 3,3,-Substituted H8-PhosphoramiditesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2009Giulia Erre Abstract In situ generated iridium complexes containing bulky 3,3,-substituted H8-phosphoramidites as ligands catalyse the asymmetric hydrogenation of non-functionalised enamides in high yield and good to excellent selectivity. [source] Highly Efficient and Versatile Phosphine-Phosphoramidite Ligands for Asymmetric HydrogenationADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 5 2009Matthias Eggenstein Abstract A set of novel phosphine-phosphoramidite ligands possessing two elements of chirality have been prepared through a modular synthetic approach. The ligands (11bS)- N -[2-(diphenylphosphino)phenyl]- N -[(S)-1-phenylethyl]dinaphtho[2,1- d:1,,2,- f][1,3,2]dioxaphosphepin-4-amine [(Sa,Sc)- 1a] and (11bR)- N -[2-(diphenylphosphino)phenyl]- N -[(S)-1-(1-naphthyl)ethyl]dinaphtho[2,1- d:1,,2,- f][1,3,2]dioxaphosphepin-4-amine [(Sa,Sc)- 1b] are unique in providing enantioselectivities ,96% ee and ,94% ee, respectively, in mechanistically distinct hydrogenations of CC, CN and CO double bonds in combination with three different transition metals (rhodium, iridium, and ruthenium, respectively). Particularly remarkable are the enantiomeric excesses up to 97% achieved in the iridium-catalyzed hydrogenation of 2-substituted quinolines, where (11bS)- N -[2-(diphenylphosphino)phenyl]- N -[(S)-1-(naphthalen-1-yl)ethyl]-8,9,10,11, 12,13,14,15-octahydrodinaphtho[2,1- d:1,,2,- f][1,3,2]dioxaphosphepin-4-amine [(Sa,Sc)- 2] proved to be the most selective ligand. Substantially lower ees were obtained with the mismatched diastereomer (Ra,Sc)- 1b and with the N -phenyl-substituted ligand 1c, missing a second element of chirality. [source] Unusual Deactivation in the Asymmetric Hydrogenation of Itaconic AcidADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 5 2009Thomas Schmidt Abstract During the asymmetric hydrogenation of itaconic acid with rhodium solvate complexes of the type [Rh(PP)(MeOH)2] BF4 (PP=DIPAMP, Me-DuPHOS) a deactivation with increasing substrate concentration is observed. It is shown that this inhibition phenomenon is due to the in situ formation of an inactive rhodium(III)-alkyl complex. Two crystal structures of single crystals of the responsible complexes (1) and (2) support the deactivation pathway. [source] Enantioselective Synthesis of Chiral ,-Aryloxy Alcohols by Asymmetric Hydrogenation of ,-Aryloxy Aldehydes via Dynamic Kinetic ResolutionADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 3 2009Zhang-Tao Zhou Abstract A catalytic enantioselective hydrogenation of racemic ,-aryloxy aldehydes via dynamic kinetic resolution has been developed by using (diamine)(spirodiphosphine)ruthenium(II) chloride [RuCl2(SDPs)(diamine)] catalysts. Employing this new reaction system a variety of optically active ,-aryloxy primary alcohols were synthesized in high yields and moderate to good enantioselectivities. [source] Highly Selective Iridium-Catalyzed Asymmetric Hydrogenation of Trifluoromethyl Olefins: A New Route to Trifluoromethyl- Bearing StereocentersADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 3 2009Mattias Engman Abstract Fluorine-containing compounds are useful in many applications ranging from pharmaceuticals to ferroelectric crystals. We have developed a new, highly enantioselective synthetic route to trifluoromethyl-bearing stereocenters in up to 96% ee via asymmetric hydrogenation using N,P-ligated iridium catalysts. We also hydrogenated an isomeric mixture of olefins; this reaction gave the hydrogenation product highly enantioselectively (87% ee), and only the E isomer was present after the reaction had reached 56% conversion. [source] Kinetic Study of the Asymmetric Hydrogenation of Methyl Acetoacetate in the Presence of a Ruthenium Binaphthophosphepine ComplexADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 1-2 2009Eva Öchsner Abstract The asymmetric hydrogenation of methyl acetoacetate (MAA) in methanol using dibromobis{(S)-4-phenyl-4,5-dihydro-3H -dinaphtho[2,1- c: 1,,2,- e]phosphepine}-ruthenium was studied in detail. For the determination of the reaction network, data from kinetic experiments were compared to different possible reaction networks using the kinetic software Presto Kinetics. The simulation was optimised to describe the reaction accurately with a minimal set of process parameters and reaction equations. For the best model the reaction orders, collision factors and activation energy of all reaction steps were determined. Additionally, the influence of reaction temperature and hydrogen pressure on the enantiomeric excess (ee) of the reaction was studied. It was found that high reaction temperatures and high hydrogen pressures result in increasing enantioselectivities. [source] Convenient General Asymmetric Synthesis of Roche Ester Derivatives through Catalytic Asymmetric Hydrogenation: Steric and Electronic Effects of LigandsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 16 2008Cyrielle Pautigny Abstract An efficient and concise asymmetric hydrogenation of acrylate esters promoted by the cationic ruthenium monohydride complex [Ru(H)(,6 -cot)SYNPHOS]+BF4, is reported. A full investigation of the effects of catalyst precursors, solvents, temperature, hydrogen pressure, substrates as well as steric and electronic properties of ligands was carried out. The corresponding valuable Roche ester derivatives were obtained in good to excellent isolated yields and high enantioselectivities under mild conditions. The robustness and practicability of this highly enantioselective hydrogenation was demonstrated by the synthesis of the 3-hydroxy-2-methylpropanoic acid tert -butyl ester on a multigram scale, resulting in excellent yield and ee up to 94%. [source] The Synthesis of Spirobitetraline Phosphoramidite Ligands and their Application in Rhodium-Catalyzed Asymmetric HydrogenationADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 16 2007Xiang-Hong Huo Abstract A racemic 1,1, - spirobitetralin-8,8,-diol (SBITOL) was conveniently synthesized from 3-methoxybenzaldehyde in 26,% yield over 9 steps and resolved via its bis-(S)-camphorsulfonates. The corresponding chiral spirobitetraline monophosphoramidite ligands have been prepared and their rhodium complexes were applied in the asymmetric hydrogenation of dehydroamino esters with good to excellent enantioselectivities (up to 99.3,% ee). [source] An Efficient Approach to Chiral Ferrocene-Based Secondary Alcohols via Asymmetric Hydrogenation of Ferrocenyl KetonesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 3 2006Wing-Sze Lam Abstract P-Phos-ruthenium-DPEN precatalysts have been found to be efficient for the asymmetric hydrogenation of various ferrocenyl ketones. The use of (R)-xylyl-P-PhosRuCl2(R,R)-DPEN generated chiral ferrocenylethanol in 99.3% e.e. with >99% conversion in a 150-g scale. [source] Bulky Achiral Triarylphosphines Mimic BINAP in Ru(II)- Catalyzed Asymmetric Hydrogenation of KetonesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 9 2005Qing Jing Abstract In the present work, we report on catalysis of the enantioselective hydrogenation of ketones with Ru(II) complexes composed of cheap achiral monodentate phosphine ligands in combination with an enantiopure 1,2-diamine, affording a variety of optically active secondary alcohols with high efficiency and enantioselectivity. The steric impact of achiral monophosphine ligands in Ru complexes was found to be a critical factor for the high enantioselectivity of the reaction. This finding throws some light on a long-standing challenge, the high cost of chiral bisphosphine ligands, associated with an industrial application of the asymmetric hydrogenation of ketones. [source] A Convenient Synthesis of 2,2,,6,6,-Tetramethoxy- 4,4,-bis(dicyclohexylphosphino)-3,3,-bipyridine (Cy-P-Phos): Application in Rh-Catalyzed Asymmetric Hydrogenation of ,-(Acylamino)acrylatesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 4 2005Jing Wu Abstract The first example of the synthesis of an axially chiral bis(aryldicyclohexylphosphine) dioxide via catalytic hydrogenation of the optically resolved parent bis(aryldiphenylphosphine) dioxide was reported. The procedure for the synthesis of Cy-P-Phos (4d) has thus successfully avoided the need for an otherwise lengthy synthetic route owing to the ,-excessive nature of one of the aryl groups in the latter. The use of Cy-P-Phos in the Rh(I)-catalyzed asymmetric hydrogenation of the derivatives of methyl (Z)-2-acetamidocinnamate gave significantly higher rates of reaction as compared to the use of the previously reported optimal ligand Xyl-P-Phos (4c) whilst the level of enantioselectivity was essentially maintained. [source] Synthesis of Diastereomeric 1,4-Diphosphine Ligands Bearing Imidazolidin-2-one Backbone and Their Application in Rh(I)-Catalyzed Asymmetric Hydrogenation of Functionalized OlefinsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 4 2005Jian Zhang Abstract The diastereomeric 1,4-diphosphine ligands, (S,S,S,S)- 1a, (R,S,S,R)- 1b and (R,S,S,S)- 1c, with the imidazolidin-2-one backbone were synthesized, and utilized for an investigation of the effects of backbone chirality on the enantioselectivity in the Rh(I)-catalyzed hydrogenation of various functionalized olefinic substrates. It was found that the catalytic efficiencies are largely dependent on the configurations of the ,-carbons to phosphine. Thus, the Rh complex of the pseudo- C2 -symmetrical diphosphine, (R,S,S,S)- 1c, showed excellent enantioselectivities (93.0,98.6% ees) in the hydrogenations of a broad spectrum of substrates, and especially in the hydrogenations of methyl ,-(N -acetyamino)-,-arylacrylates (95.3,97.0% ees). However, the enantioselectivities obtained with the C2 -symmetrical (R,S,S,R)- 1b were largely dependent on the substrate (19.8,97.3% ees). The Rh complex of ligand 1a having the (S,S,S,S)-configuration showed the lowest catalytic efficiency for all of the substrates examined (0,84.8% ees). [source] Non-Linear Effect of Modifier Composition on Enantioselectivity in Asymmetric Hydrogenation over Platinum MetalsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 1-2 2003Wolf-Rüdiger Huck Abstract Prominent non-linear behavior was observed when mixtures of cinchona alkaloids were applied as chiral modifiers in enantioselective hydrogenations over Pt/Al2O3 and Pd/TiO2. The phenomenon is traced to differences in the strength and geometry of alkaloid adsorption on the metal surface. In ethyl pyruvate hydrogenation under close to ambient conditions the weaker adsorbing quinidine (QD) outperformed the generally preferred modifier cinchonidine (CD) and afforded the highest ee (96,98%) at 1,5,bar. In the partial hydrogenation of 4-methoxy-6-methyl-2-pyrone to the dihydro derivative 4 CD gave 73% ee to (S)- 4 and QD provided 72% ee to (R)- 4, and still the alkaloid mixture containing less than 5,mol,% CD afforded 15% ee to (S)- 4. This non-linear behavior may be advantageous in asymmetric synthesis as low purity chiral compounds can be applied as efficient modifiers for Pt or Pd. [source] Asymmetric Hydrogenation of Quinoxalines with Diphosphinite Ligands: A Practical Synthesis of Enantioenriched, Substituted Tetrahydroquinoxalines,ANGEWANDTE CHEMIE, Issue 48 2009Weijun Tang Dr. Leicht zugänglich ist ein chiraler Iridium-(H8 -Binapo)-Katalysator, der die hoch enantioselektive Hydrierung von Chinoxalinen bei hohen Substrat/Katalysator-Verhältnissen von 100 bis 20,000 vermittelt. Die neue Methode dient als praktischer Ansatz für die Synthese optisch aktiver Tetrahydrochinoxalin-Derivate (siehe Schema; cod=1,5-Cyclooctadien). [source] ChemInform Abstract: Iridium-Catalyzed Asymmetric Hydrogenation of N-Protected Indoles.CHEMINFORM, Issue 24 2010Alejandro Baeza Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Novel, Tunable, and Efficient Chiral Bisdihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation.CHEMINFORM, Issue 23 2010Wenjun Tang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Ru-Catalyzed Asymmetric Hydrogenation of Aryl Ketones Using Tetrazole Derived NH2 -Hybrid Ligand.CHEMINFORM, Issue 17 2010Fusheng Bie Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Asymmetric Hydrogenation of Quinoxalines with Diphosphinite Ligands: A Practical Synthesis of Enantioenriched, Substituted Tetrahydroquinoxalines.CHEMINFORM, Issue 12 2010Weijun Tang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Highly Enantioselective Synthesis of Chiral Cyclic Amino Alcohols and Conhydrine by Ruthenium-Catalyzed Asymmetric Hydrogenation.CHEMINFORM, Issue 11 2010Sheng Liu Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: NeoPHOX , An Easily Accessible P,N-Ligand for Iridium-Catalyzed Asymmetric Hydrogenation: Preparation, Scope and Application in the Synthesis of Demethyl Methoxycalamenene.CHEMINFORM, Issue 10 2010Marcus G. Schrems Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Modular Synthesis of the ClickFerrophos Ligand Family and Their Use in Rhodium- and Ruthenium-Catalyzed Asymmetric Hydrogenation.CHEMINFORM, Issue 9 2010Hiroshi Oki Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] | |||||||||||||||||||||||||