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Pioneering Work (pioneering + work)
Selected AbstractsEnhancing the effectiveness of residential treatment for substance abusing pregnant and parenting women: Focus on maternal reflective functioning and mother-child relationshipINFANT MENTAL HEALTH JOURNAL, Issue 5 2006Marjukka Pajulo Substance abuse during early motherhood has become a significant problem and has led to accelerated efforts to develop specific treatment facilities for these mothers and children. Despite the often intensive treatment efforts in residential settings, there is surprisingly little evidence of their efficacy for enhancing the quality of caregiving. The situation of these mother-child pairs is exceptionally complex and multilevel, and has to be taken into account in the content and structuring of treatment. Intensive work in the "here and now" focusing on the mother-child relationship from pregnancy onwards in an effort to enhance maternal reflective capacity and mindedness is considered a key element for better treatment prognosis, in terms of both abstinence and quality of parenting. Pioneering work with such a focus is described in this article. [source] Guidelines for species descriptions of diplomonad flagellates from fishJOURNAL OF FISH DISEASES, Issue 1 2002S L Poynton Diplomonad flagellates are common commensals of the digestive tract, and less common pathogenic parasites occurring in the digestive tract and systemically in numerous fish species. Many aspects of infections are poorly understood, including host-flagellate specificity, geographic ranges, and pathogenicity of different species. Much confusion is attributable to inadequate determination of genus and species. Although older literature reports Hexamita, Octomitus and Spironucleus from fish, recent studies confirm only Spironucleus. To address this problem, we describe ultrastructural features of trophozoites permitting reliable identification to genus and species, and techniques for their elucidation. Pioneering work by Brugerolle and colleagues established that genera can be distinguished by transmission electron microscopy (TEM). We now demonstrate that at the species level, surface ornamentations (especially at the posterior end of the body), and the pattern of bands of microtubules accompanying the flagellar pocket (in transverse section through the middle of the body), are of particular taxonomic value. Both scanning and TEM are essential for robust species descriptions and type material must be deposited in a recognized reference collection. Taxonomic studies are enhanced by in vitro culture, with tolerance and optimum for different conditions providing important supplementary information. Molecular characterization of fish diplomonads is in its infancy. [source] A novel bacterial signalling system with a combination of a Ser/Thr kinase cascade and a His/Asp two-component systemMOLECULAR MICROBIOLOGY, Issue 2 2005Renate Lux Summary Prokaryotes and eukaryotes have long been thought to use very different types of kinases (the His kinases of the ,bacterial' two-component systems versus the ,eukaryotic' Ser/Thr/Tyr kinases) to carry out signal transduction. This paradigm no longer holds true, because both systems are now found together in an increasing number of prokaryotic organisms and ,two-component' His kinase are present in eukaryotes. Pioneering work on bacterial protein serine threonine kinases (PSTKs) has been performed in Myxococcus xanthus, a soil bacterium with a complex life cycle that possesses orthologues of signalling-related kinases ,typical' of both the prokaryotic and the eukaryotic kingdoms. In the work reported in this volume of Molecular Microbiology, Nariya and Inouye describe a PSTK cascade that modulates the biochemical activity of MrpC, a CRP-like transcriptional regulator for essential developmental signalling pathways in M. xanthus whose transcription is under the control of a two-component system. This is the first report of both a functional PSTK cascade in bacteria and the use of both PSTK and two-component systems to control a single complex bacterial signalling event. [source] Volume natriuresis vs. pressure natriuresisACTA PHYSIOLOGICA, Issue 4 2004P. Bie Abstract Body fluid regulation depends on regulation of renal excretion. This includes a fast vasopressin-mediated water-retaining mechanism, and slower, complex sodium-retaining systems dominated by the renin,angiotensin aldosterone cascade. The sensory mechanisms of sodium control are not identified; effectors may include renal arterial pressure, renal reflexes, extrarenal hormones and other regulatory factors. Since the pioneering work of Guyton more than three decades ago, pressure natriuresis has been in focus. Dissociations between sodium excretion and blood pressure are explained as conditions where regulatory performance exceeds the precision of the measurements. It is inherent to the concept, however, that sudden transition from low to high sodium intake elicits an arterial pressure increase, which is reversed by the pressure natriuresis mechanism. However, such transitions elicit parallel changes in extracellular fluid volume thereby activating volume receptors. Recently we studied the orchestration of sodium homeostasis by chronic and acute sodium loading in normal humans and trained dogs. Small increases in arterial blood pressure are easily generated by acute sodium loading, and dogs appear more sensitive than humans. However, with suitable loading procedures it is possible , also acutely , to augment renal sodium excretion by at least one order of magnitude without any change in arterial pressure whatsoever. Although pressure natriuresis is a powerful mechanism capable of overriding any other controller, it seems possible that it is not operative under normal conditions. Consequently, it is suggested that physiological control of sodium excretion is neurohumoral based on extracellular volume with neural control of renin system activity as an essential component. [source] Modeling the model organism Dictyostelium discoideumDEVELOPMENT GROWTH & DIFFERENTIATION, Issue 6 2000Seido Nagano The cellular slime mold Dictyostelium discoideum is a fascinating organism, not only for biologists, but also for physicists. Since the Belousov,Zhabotinskii reaction pattern, a well-known non-linear phenomenon in chemistry, was observed during aggregation of Dictyostelium amoebae, Dictyostelium has been one of the major subjects of non-linear dynamics studies. Macroscopic theory, such as continuous cell density approximation, has been a common approach to studying pattern formation since the pioneering work of Turing. Recently, promising microscopic approaches, such as the cellular dynamics method, have emerged. They have shown that Dictyostelium is useful as a model system in biology. The synchronization mechanism of oscillatory production of cyclic adenosine 3,,5,-monophosphate in Dictyostelium is discussed in detail to show how it is a universal feature that can explain synchronization in other organisms. [source] Sequential activation of transcription factors in lens inductionDEVELOPMENT GROWTH & DIFFERENTIATION, Issue 5 2000Hajime Ogino Since the pioneering work of the early 1900s, the lens has been used as a model system for the study of tissue development in vertebrates. A number of embryological transplantation experiments designed to elucidate the role of tissue interactions in the formation of the lens have led to the proposal of a stepwise determination model. This model has recently been refined through the identification of certain transcription factor genes, which exhibit distinct expression patterns and functional properties in the lens cell lineage. Otx2, Pax6, and Lens1 are induced by the adjacent anterior neural plate and expressed in predifferentiated lens ectoderm. Contact between the optic vesicle and lens ectoderm promotes expression of mafs, Soxs, and Prox1, which are responsible for the initiation of lens differentiation programs including crystallin expression, cell elongation, and cell cycle arrest. Further analysis of the expression and functional characteristics of these transcription factors will allow greater detail when describing the orchestration of genetic programs, which control tissue development from induction to maturation. [source] An iris recognition approach through structural pattern analysis methodsEXPERT SYSTEMS, Issue 1 2010Hugo Proença Abstract: Continuous efforts have been made to improve the robustness of iris coding methods since Daugman's pioneering work on iris recognition was published. Iris recognition is at present used in several scenarios (airport check-in, refugee control etc.) with very satisfactory results. However, in order to achieve acceptable error rates several imaging constraints are enforced, which reduce the fluidity of the iris recognition systems. The majority of the published iris recognition methods follow a statistical pattern recognition paradigm and encode the iris texture information through phase, zero-crossing or texture-analysis based methods. In this paper we propose a method that follows the structural (syntactic) pattern recognition paradigm. In addition to the intrinsic advantages of this type of approach (intuitive description and human perception of the system functioning), our experiments show that the proposed method behaves comparably to the statistical approach that constitutes the basis of nearly all deployed systems. [source] The Financialization of Urban RedevelopmentGEOGRAPHY COMPASS (ELECTRONIC), Issue 8 2010Ted Rutland Spurred by the conviction that not only financial capital but also changes in finance and changes in its relations with non-financial activities have immense and complicated consequences for ongoing processes of urban redevelopment, this article puts the presently separate financialization and urban redevelopment literatures in conversation. The article begins with a review of the financialization literature, outlining and evaluating four different approaches to the topic and seeking to consider what, if anything, they might have to offer to an area of inquiry that has long considered finance to be a central concern. The second section examines how financial capital has been analyzed in the urban redevelopment literature since the pioneering work of David Harvey in the 1970s. The final section examines how financialization has played out in the medium-sized port city of Halifax, Nova Scotia. Drawing on interviews with financiers and property developments, as well as secondary research materials, the study describes how a recent urban design process in Halifax enlisted urban images and ideas to rewrite development regulations, eliminate popular political involvement in the development approvals process, and lever open the downtown landscape to the whims of worldwide financial markets. The essay concludes that studies of urban redevelopment would indeed gain something by engaging with the financialization literature, so long as the former continue to attend not just to financial capital but also to the material and ideological mechanisms through which property is continually reproduced as a financial asset. [source] Arriving at a strategic theory of the firmINTERNATIONAL JOURNAL OF MANAGEMENT REVIEWS, Issue 4 2000Steven E. Phelan The theory of the firm seeks to explain the existence and boundaries of the firm in relation to the market. Since the pioneering work of Coase (The nature of the firm. Economica, 4, 386,405, 1937), economics has developed a whole family of theories that focus on the ability of firms to economize on certain costs of using markets. More recently, researchers in strategic management have published several theories of the firm that have tended to emphasize the benefits of incorporation rather than the costs of using the market. Although researchers in the strategy profession have tentatively labeled their work as ,moving towards' a strategic theory of the firm, economists have been very critical of existing approaches. This paper seeks to begin ,arriving' at a strategic theory of the firm by addressing these criticisms and offering an integration of the strategic and economic perspectives within an institutional framework. The paper concludes with future directions for research in the theory of the firm. [source] Sexual Differentiation of Behaviour in Monkeys: Role of Prenatal HormonesJOURNAL OF NEUROENDOCRINOLOGY, Issue 4 2009K. Wallen The theoretical debate over the relative contributions of nature and nurture to the sexual differentiation of behaviour has increasingly moved towards an interactionist explanation that requires both influences. In practice, however, nature and nurture have often been seen as separable, influencing human clinical sex assignment decisions, sometimes with disastrous consequences. Decisions about the sex assignment of children born with intersex conditions have been based almost exclusively on the appearance of the genitals and how other's reactions to the gender role of the assigned sex affect individual gender socialisation. Effects of the social environment and gender expectations in human cultures are ubiquitous, overshadowing the potential underlying biological contributions in favour of the more observable social influences. Recent work in nonhuman primates showing behavioural sex differences paralleling human sex differences, including toy preferences, suggests that less easily observed biological factors also influence behavioural sexual differentiation in both monkeys and humans. We review research, including Robert W. Goy's pioneering work with rhesus monkeys, which manipulated prenatal hormones at different gestation times and demonstrated that genital anatomy and specific behaviours are independently sexually differentiated. Such studies demonstrate that, for a variety of behaviours, including juvenile mounting and rough play, individuals can have the genitals of one sex but show the behaviour more typical of the other sex. We describe another case, infant distress vocalisations, where maternal responsiveness is best accounted for by the mother's response to the genital appearance of her offspring. Taken together, these studies demonstrate that sexual differentiation arises from complex interactions where anatomical and behavioural biases, produced by hormonal and other biological processes, are shaped by social experience into the behavioural sex differences that distinguish males and females. [source] Intratumoral cancer chemotherapy and immunotherapy: opportunities for nonsystemic preoperative drug deliveryJOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATI ONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Issue 2 2002Eugene P. Goldberg The recent literature documents the growing interest in local intratumoral chemotherapy as well as systemic preoperative chemotherapy with evidence for improved outcomes using these therapeutic modalities. Nevertheless, with few exceptions, the conventional wisdom and standard of care for clinical and surgical oncology remains surgery followed by radiation and/or systemic chemotherapy, as deemed appropriate based on clinical findings. This, in spite of the fact that the toxicity of conventional systemic chemotherapy and immunotherapy affords limited effectiveness and frequently compromises the quality of life for patients. Indeed, with systemic chemotherapy, the oncologist (and the patient) often walks a fine line between attempting tumour remission with prolonged survival and damaging the patient's vital functions to the point of death. In this context, it has probably been obvious for more than 100 years, due in part to the pioneering work of Ehrlich (1878), that targeted or localized drug delivery should be a major goal of chemotherapy. However, there is still only limited clinical use of nonsystemic intratumoral chemotherapy for even those high mortality cancers which are characterized by well defined primary lesions i.e. breast, colorectal, lung, prostate, and skin. There has been a proliferation of intratumoral chemotherapy and immunotherapy research during the past two to three years. It is therefore the objective of this review to focus much more attention upon intratumoral therapeutic concepts which could limit adverse systemic events and which might combine clinically feasible methods for localized preoperative chemotherapy and/or immunotherapy with surgery. Since our review of intratumoral chemo-immunotherapy almost 20 years ago (McLaughlin & Goldberg 1983), there have been few comprehensive reviews of this field; only one of broad scope (Brincker 1993), three devoted specifically to gliomas (Tomita 1991; Walter et al. 1995; Haroun & Brem 2000), one on hepatomas (Venook 2000), one concerning veterinary applications (Theon 1998), and one older review of dermatological applications (Goette 1981). However, none have shed light on practical opportunities for combining intratumoral therapy with subsequent surgical resection. Given the state-of-the-art in clinical and surgical oncology, and the advances that have been made in intratumoral drug delivery, minimally invasive tumour access i.e. fine needle biopsy, new drugs and drug delivery systems, and preoperative chemotherapy, it is timely to present a review of studies which may suggest future opportunities for safer, more effective, and clinically practical non-systemic therapy. [source] Origins and Applications of London Dispersion Forces and Hamaker Constants in CeramicsJOURNAL OF THE AMERICAN CERAMIC SOCIETY, Issue 9 2000Roger H. French The London dispersion forces, along with the Debye and Keesom forces, constitute the long-range van der Waals forces. London's and Hamaker's work on the point-to-point dispersion interaction and Lifshitz's development of the continuum theory of dispersion are the foundations of our understanding of dispersion forces. Dispersion forces are present for all materials and are intrinsically related to the optical properties and the underlying interband electronic structures of materials. The force law scaling constant of the dispersion force, known as the Hamaker constant, can be determined from spectral or parametric optical properties of materials, combined with knowledge of the configuration of the materials. With recent access to new experimental and ab initio tools for determination of optical properties of materials, dispersion force research has new opportunities for detailed studies. Opportunities include development of improved index approximations and parametric representations of the optical properties for estimation of Hamaker constants. Expanded databases of London dispersion spectra of materials will permit accurate estimation of both nonretarded and retarded dispersion forces in complex configurations. Development of solutions for generalized multilayer configurations of materials are needed for the treatment of more-complex problems, such as graded interfaces. Dispersion forces can play a critical role in materials applications. Typically, they are a component with other forces in a force balance, and it is this balance that dictates the resulting behavior. The ubiquitous nature of the London dispersion forces makes them a factor in a wide spectrum of problems; they have been in evidence since the pioneering work of Young and Laplace on wetting, contact angles, and surface energies. Additional applications include the interparticle forces that can be measured by direct techniques, such as atomic force microscopy. London dispersion forces are important in both adhesion and in sintering, where the detailed shape at the crack tip and at the sintering neck can be controlled by the dispersion forces. Dispersion forces have an important role in the properties of numerous ceramics that contain intergranular films, and here the opportunity exists for the development of an integrated understanding of intergranular films that encompasses dispersion forces, segregation, multilayer adsorption, and structure. The intrinsic length scale at which there is a transition from the continuum perspective (dispersion forces) to the atomistic perspective (encompassing interatomic bonds) is critical in many materials problems, and the relationship of dispersion forces and intergranular films may represent an important opportunity to probe this topic. The London dispersion force is retarded at large separations, where the transit time of the electromagnetic interaction must be considered explicitly. Novel phenomena, such as equilibrium surficial films and bimodal wetting/dewetting, can result in materials systems when the characteristic wavelengths of the interatomic bonds and the physical interlayer thicknesses lead to a change in the sign of the dispersion force. Use of these novel phenomena in future materials applications provides interesting opportunities in materials design. [source] Writing Eighteenth-Century Women's Literary History, 1986 to 2006LITERATURE COMPASS (ELECTRONIC), Issue 6 2007Betty A. Schellenberg Under the influence of feminist theory and criticism, the late 1980s saw a flowering of literary histories of eighteenth-century women writers. This work was very influential in assuming the existence of a distinct women's literary history conditioned by an increasingly rigid gender ideology of the time, in focusing on the novel genre, and in creating appreciation for the more recognizably feminist writers of the early and latter portions of the ,long eighteenth century'. Subsequent work questioned the dependence of these histories on the ,separate spheres' model of gender, on a limited group of genres associated with women and with the literary, and on notions of feminism congenial to the late-twentieth-century critic. More broadly, feminist generalizations of women's experience were challenged by the rise of class, race and sexuality studies, while the very enterprise of historiography was placed under suspicion by postmodernist criticism of master narratives and of claims to objective interpretation of evidence. In response, studies of eighteenth-century women's writing began to attend to a broader range of genres and spheres of action within the larger field of print culture, as well as to produce more nuanced studies of individual writers and the conditions within which they wrote. However, general literary studies remained dependent on the models of the 1980s, while writers seemed reluctant to write new literary histories. Only recently are there indications of a return to large-scale women's literary histories. This return revises the pioneering work of the 1980s by attending to new, detailed studies of numerous individual writers, expanding generic coverage, incorporating electronic resources, experimenting with inclusive studies of male and female writers, and reconsidering questions of literary value. [source] `It teaches you what to expect in future,': interprofessional learning on a training ward for medical, nursing, occupational therapy and physiotherapy studentsMEDICAL EDUCATION, Issue 4 2002Scott Reeves Aim This paper presents findings from a multimethod evaluation of an interprofessional training ward placement for medical, nursing, occupational therapy and physiotherapy students. Context Unique in the UK, and following the pioneering work at Linköping, the training ward allowed senior pre-qualification students, under the supervision of practitioners, to plan and deliver interprofessional care for a group of orthopaedic and rheumatology patients. This responsibility enabled students to develop profession-specific skills and competencies in dealing with patients. It also allowed them to enhance their teamworking skills in an interprofessional environment. Student teams were supported by facilitators who ensured medical care was optimal, led reflective sessions and facilitated students' problem solving. Methods Data were collected from all groups of participants involved in the ward: students, facilitators and patients. Methods included questionnaires, interviews and observations. Results and discussion Findings are presented from each participating group, with a particular emphasis placed on the perspective of medicine. The study found that students valued highly the experiential learning they received on the ward and felt the ward prepared them more effectively for future practice. However, many encountered difficulties adopting an autonomous learning style during their placement. Despite enjoying their work on the ward, facilitators were concerned that the demands of their role could result in `burn-out'. Patients enjoyed their ward experience and scored higher on a range of satisfaction indicators than a comparative group of patients. Conclusions Participants were generally positive about the training ward. All considered that it was a worthwhile experience and felt the ward should recommence in the near future. [source] Using the past to shape the future: new concepts for a historic siteMUSEUM INTERNATIONAL, Issue 1 2001Ruth J. Abram Ruth J. Abram is the founder and president of the Lower East Side Tenement Museum in New York City. An activist turned historian, Ms Abram holds graduate degrees in social welfare and American history, and has done pioneering work in the use of history for social issues. Her landmark work at the Tenement Museum has been widely covered in the media in the United States, including the New York Times, World News Tonight with Peter Jennings and the Public Broadcasting System series on the history of New York. Her work indeed sheds light on history from the point of view of those who are often left out of the history books. [source] Anténor Firmin: Haitian Pioneer of AnthropologyAMERICAN ANTHROPOLOGIST, Issue 3 2000Carolyn Fluehr-Lobban Anténor Firmin published De I'Égalité des Races Humaines in 1885 in Paris as a response both to Arthur de Gobineau's racist tome L'lnégalité des Races (1853-55) and to the racialist anthropology of the nineteenth century. This pioneering work of anthropology has been translated for the first time into English by Assclin Charles as The Equality of the Human Races (Firmin [1885]2000). In 662 pages of the original text, Firmin systematically critiqued the anthropometry and craniometry that dominated the anthropology of his day, while he envisioned a broad, synthetic discipline that would follow once this narrow approach to the study of man was abandoned. He challenged virtually every extant racial myth and laid a basis for the understanding of human variation as adaptation to climate and environment. Contrary to the polygenist doctrines of the infertility of interracial matings, Firmin extolled the value of racial mixture, especially in the vigorous New World hybrid populations. He developed a critical view of racial classifications and of race that foreshadowed much later social constructions of race. In the book he also articulated early Pan-Africanist ideas as well as an analytical framework for what would become postcolonial studies. The Equality of the Human Races is a text that lies historically at the foundations of the birth of the discipline of anthropology, yet it is unknown to the field. It is a pioneering work in critical anthropology that awaits recognition 115 years after it was first published. [Anténor Firmin, history of racism, antiracism, historical texts, Haitian anthropologist, critical anthropology, nineteenth-century pioneer] [source] The Henry George Theorem and the Entrepreneurial Process: Turning Henry George on his HeadAMERICAN JOURNAL OF ECONOMICS AND SOCIOLOGY, Issue 1 2010Laurence S. Moss This chapter offers an interpretation of the Henry George Theorem (HGT) that brings it squarely into the study and analysis of entrepreneurship somewhat loosening its ties to the subfield of urban economics. I draw on the pioneering work of Spencer Heath whose insights about the viability of proprietary communities were developed further by his grandson, Spencer Heath MacCallum who, in 1970, recognized that private real estate developers sometimes make their capital gains (mostly) by creating useful public spaces that others enjoy. I also draw inspiration from Fred Foldvary's effort in 1994 to synthesize the pubic goods problem in economics with the Henry George Theorem in urban economics. While the real estate owner,developer does emerge on my pages in a somewhat more favourable light than as originally portrayed by Henry George in his Progress and Poverty in 1879, I offer a realistic appraisal of the duplicitous behaviours required of such entrepreneurs. in the context of the modern regulatory state. Real estate development remains a ,hot button' item in local politics, and real estate developers must become genuine ,political entrepreneurs' if they are to complete their projects in a timely way and capture business profits. It is a complicated story that the HGT helps make intelligible in terms of human action. [source] Sunao Tawara: A Father of Modern CardiologyPACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 1 2001KOZO SUMA SUMA, K.: Sunao Tawara: A Father of Modern Cardiology. Knowledge of the conduction system of the heart was greatly advanced by Tawara's work carried out in Aschoff's laboratory in Marburg at the beginning of this century. In his monograph, The Conduction System of the Mammalian Heart, published in 1906, Tawara indicated that the treelike structure of specific muscle fibers comprising the atrioventricular node, His bundle, bundle branches, and Purkinje fibers served as the pathway for atrioventricular conduction of excitation in the mammalian heart. From his own anatomic and histological findings of the conduction system, he assumed precisely that the conduction velocity of excitation in the system, except in the atrioventricular node, would be fast and that contraction as the result of excitation would take place at the various sites of the ventricles almost simultaneously. According to Tawara, a long pathway to each contracting unit and a fast conduction velocity of excitation would be a prerequisite for the effective contraction of the ventricles. Tawara's findings and assumptions provided Einthoven the theoretical basis for interpreting the electrocardiogram, resulting in rapid popularization of electrocardiography. This century has witnessed the rapid progress of cardiology, including cardiac pacing and its related sciences. This progress has its roots in the discovery of the conduction system and the development of electrocardiography that took place almost in the same period at the beginning of this century. Tawara's pioneering work on the conduction system still serves as an invaluable reference for basic and clinical research. [source] Hydrogels as smart biomaterialsPOLYMER INTERNATIONAL, Issue 9 2007ich Kope Abstract Hydrogels were the first biomaterials rationally designed for human use. Beginning with the pioneering work of Wichterle and Lím on three-dimensional polymers that swell in water, we review the design, synthesis, properties, and applications of hydrogels. The field of hydrogels has moved forward at a dramatic pace. The development of suitable synthetic methods encompassing traditional chemistry to molecular biology has been used in the design of hydrogels mimicking basic processes of living systems. Stimuli-sensitive hydrogels, hydrogels with controlled degradability, genetically engineered poly(amino acid) polymers reversibly self-assembling in precisely defined three-dimensional structures, and hybrid polymers composed of two distinct classes of molecules are just some examples of these exciting novel biomaterials. The biocompatibility of hydrogels and their applications from implants to nanomaterials are also reviewed. Copyright © 2007 Society of Chemical Industry [source] Specialization, Context of Production, and Alienation in the Production Process: Comments and AfterthoughtsARCHEOLOGICAL PAPERS OF THE AMERICAN ANTHROPOLOGICAL ASSOCIATION, Issue 1 2007Yung-ti Li The study of craft specialization has gone through several stages since the pioneering work of Childe, each with changing foci and emphases. The current volume marks yet another development in the field that demonstrates both discontents with existing theories and efforts to enhance and strengthen the discourse. Acting as a commentator to facilitate further discussion, the first half of my chapter addresses specific issues in individual chapters, while the second half explores another dimension of production by looking at bronze and pottery production in ancient and premodern China. Whereas some contributors examine alienability in the social role of the objects and the rights over alienation of the product, this discussion examines another form of alienation that can be considered in the study of craft production, one that is both salient and tangible in archaeological data: alienation of the manufacturing process, that is, alienation of the craft producers from their own skills. The work of Ursula Franklin on Shang bronze production is reviewed, and new studies on porcelain production at Jingdezhen and stoneware production at Yixing are incorporated to further develop Franklin's model. I argue that through examining the material patterns of the production process and the type range of finished products, alienation in the workplace can be detected archaeologically. [source] Intersectoral Linkages and Key Sectors in China, 1987,1997ASIAN ECONOMIC JOURNAL, Issue 2 2004B. Andreosso-O'Callaghan Since the pioneering work by Rasmussen and others in the 1950s, alternative measures of linkages have been developed, with the aim of examining the interdependence in production structures and in identifying key sectors in an economy. Our study proposes a comparative analysis of traditional and modern methods, by applying them to the case of China between 1987 and 1997. It finds that backward and forward linkages have generally increased in China, denoting an increase in intersectoral interdependence, with some sectors (e.g. agriculture, food, textiles and chemicals) being dominant in this process. With regard to the identification of key sectors, hypothetical extraction methods provide superior results compared with traditional methods. Agriculture, textiles, chemicals, building materials, primary metals, machinery, commerce and other services are all recognized as being the key sectors by both the total linkage and pure linkage methods. [source] From Gauß to Biermann: Highlights from the first 117 years of publications in Astronomische Nachrichten/Astronomical NotesASTRONOMISCHE NACHRICHTEN, Issue 6 2009R. von Berlepsch Abstract We present facsimiles of some of the scientifically and historically most relevant papers published in Astronomische Nachrichten/Astronomical Notes (AN) between 1821 and 1938. Almost all of these papers were written and printed in German and it is sometimes not completely straightforward to find these original works and then to cite the historically correct version, e.g. in case of a series of articles or editorial letters. It was common during the early years that many contributions were made in form of letters to the editor. We present a summary for these original works with an English translation of their titles. Among the highlights are the originals of the discovery of stellar parallaxes by FriedrichWilhelm Bessel, the discovery of the solar cycle by Heinrich Schwabe, the discovery of the planet Neptune by Johann Gottfried Galle, the first ever measured stellar radial velocity by Hermann Vogel, the discovery of radio emission from the Sun by Wilsing and Scheiner, the first ever conducted photoelectric photometry of stars by Paul Guthnick and up to the pioneering work by Karl Schwarzschild, Ejnar Hertzsprung, Erwin Finlay Freundlich and others. As a particular gimmick we present the still world record holding shortest paper ever published; by Johannes Hartmann in AN 226, 63 (1926) on Nova Pictoris. Our focus is on contributions in the early years and published until 1938 near the verge of the second world war (© 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] A Festschrift in Honor of Professor R.W. SmithellsBIRTH DEFECTS RESEARCH, Issue 4 2009Mary Seller This issue of Birth Defects Research Part A: Clinical and Molecular Teratology, comprises a Festschrift, a tribute to Professor R. W. (Dick) Smithells (1924-2002). In the 1970s, Dick initiated a study on the prevention of neural tube defects (NTD) by periconceptional multivitamin and folic acid supplementation of ,at risk' women. A significantly positive result was obtained,the first time that the primary prevention of any congenital malformation had ever been achieved. This important discovery stimulated an explosion of similar and related studies, and over the years, an extension of research into many closely allied but disparate fields. The papers in this Festschrift tell some of this story. However, the story itself has, as yet, no ending, because despite Dick's pioneering work and all our accumulated knowledge, the precise cause of NTD, and its mechanism, remains unknown. The authors contributing to this issue dedicate their work to the memory of Dick, and together with many other scientists, doctors and patients worldwide acknowledge and pay homage to his inspiration, industry and foresight. Birth Defects Research (Part A), 2009. © 2009 Wiley-Liss, Inc. [source] The Concept of Solidarity: Emerging from the Theoretical Shadows?BRITISH JOURNAL OF POLITICS & INTERNATIONAL RELATIONS, Issue 1 2007Lawrence Wilde The concept of solidarity has been relatively neglected by social scientists since Durkheim's pioneering work in the late 19th century. The discipline of politics has been guilty of overlooking this ,subjective' element of community life, but recent works by Stjernř and Brunkhorst reflect a growing awareness of the theoretical significance of the concept. Whereas early liberal attempts to theorise solidarity took the nation state to be the appropriate community for its realisation, the emergence of globalisation raises the possibility of human solidarity developing in the global community. Traditional forms of solidarity have been dissipated by the social changes accompanying globalisation, but they were often locked into the defence of particular interests. New forms may be emerging to rekindle the broader vision of human solidarity. Recent work by writers such as Habermas, Honneth, Rorty and Touraine focuses on widening and deepening democratic participation and/or the articulation of our ethical obligations in various ways. It is argued here that these perspectives need to be supplemented by a radical humanist approach grounded in a normative theory of human self-realisation. [source] Water Splitting on Semiconductor Catalysts under Visible-Light IrradiationCHEMSUSCHEM CHEMISTRY AND SUSTAINABILITY, ENERGY & MATERIALS, Issue 6 2009Rufino Abstract Splitting image: Sustainable hydrogen production is a key target for the development of alternative, future energy systems that will provide a clean and affordable energy supply. This Minireview focuses on the development of semiconductor catalysts that enable hydrogen production via water splitting upon visible-light irradiation. Sustainable hydrogen production is a key target for the development of alternative, future energy systems that will provide a clean and affordable energy supply. The Sun is a source of silent and precious energy that is distributed fairly all over the Earth daily. However, its tremendous potential as a clean, safe, and economical energy source cannot be exploited unless the energy is accumulated or converted into more useful forms. The conversion of solar energy into hydrogen via the water-splitting process, assisted by photo-semiconductor catalysts, is one of the most promising technologies for the future because large quantities of hydrogen can potentially be generated in a clean and sustainable manner. This Minireview provides an overview of the principles, approaches, and research progress on solar hydrogen production via the water-splitting reaction on photo-semiconductor catalysts. It presents a survey of the advances made over the last decades in the development of catalysts for photochemical water splitting under visible-light irradiation. The Minireview also analyzes the energy requirements and main factors that determine the activity of photocatalysts in the conversion of water into hydrogen and oxygen using sunlight. Remarkable progress has been made since the pioneering work by Fujishima and Honda in 1972, but he development of photocatalysts with improved efficiencies for hydrogen production from water using solar energy still faces major challenges. Research strategies and approaches adopted in the search for active and efficient photocatalysts, for example through new materials and synthesis methods, are presented and analyzed. [source] When late life brings a diagnosis of Alzheimer's Disease and early life brought trauma.CLINICAL PSYCHOLOGY AND PSYCHOTHERAPY (AN INTERNATIONAL JOURNAL OF THEORY & PRACTICE), Issue 3 2003A cognitive-analytic understanding of loss of mind This paper contrasts the loss of mind from the loss of brain cells in Alzheimer's Disease and other neurodegenerative conditions with the threats to one's mind from the mindlessness of others from a cognitive-analytic perspective. Case studies are presented that show how the therapeutic framework of Cognitive-Analytic Therapy (CAT: Ryle 1990, 1995, 1997) can bring containment for both client and therapist for clients facing this dilemma, particularly when past trauma is potentially overwhelming. This is set in a dialogue with the pioneering work of Tom Kitwood (1990, 1995, 1997) in dementia care, in which Kitwood's thesis of the ,malignant social psychology' surrounding people with dementia is re-stated in terms of ,reciprocal roles' developed in Cognitive-Analytic Therapy. Copyright © 2003 John Wiley & Sons, Ltd. [source] The Pelican Cancer Foundation and The English National MDT-TME Development ProgrammeCOLORECTAL DISEASE, Issue 2006J. Jessop Abstract The formation of The Pelican Cancer Foundation in 2000 was based around the pioneering work of Professor Bill Heald and colleagues, and the development of Total Mesorectal Excision (TME) for rectal cancer. A series of surgical workshops in Scandinavia in the mid 1990s and, later, six further workshops in the Trent region culminated in the commissioning of the fully multidisciplinary National MDT-TME Development Programme by the National Cancer Director, Professor Mike Richards, in March 2003. [source] Standardization of Network Technologies: Market Processes or the Result of Inter-Firm Co-operation?JOURNAL OF ECONOMIC SURVEYS, Issue 4 2001Bertrand Quélin As recent studies on the evolution of a technology indicate, the role of a standard, or dominant design, is highly significant in a number of contemporary industries such as computer, telecommunications and consumer electronics. Following Katz' and Shapiro's pioneering works (1985), our paper rationally evaluates the concepts and results developed over the past ten years in this field. It is grounded on a typology of two types of models: the first is based on users' anticipatory behaviour, and the second, on the collaborative behaviour of existing firms. The article initially discusses the specificity of network technologies, then analyses market standardisation models, and finally, studies the different actors models. Our conclusion builds upon existing works in network technologies. We next propose a research agenda [source] | |||||||||||||||||||||||||