			Home About us Contact

Physiological Media (physiological + media)

Distribution by Scientific Domains

Polymers and Materials Science	80%

Selected Abstracts

Electrochemically Deposited Ca(OH)2 Coatings as a Bactericidal and Osteointegrative Modification of Ti Implants

ADVANCED ENGINEERING MATERIALS, Issue 3 2009
Claus Moseke
Coating of metallic implants with CaP is a common method of improving osseointegration of the device. In this study Ca(OH)2 coatings are analyzed combining the advantage of initial bacteriocidity with,after conversion of the hydroxide to hydroxyapatite in physiological media,good osteoconductivity. [source]

In Situ Bioconjugation: Single Step Approach to Tailored Nanoparticle-Bioconjugates by Ultrashort Pulsed Laser Ablation

ADVANCED FUNCTIONAL MATERIALS, Issue 8 2009
Svea Petersen
Abstract A single step approach to tailored nanoparticle-bioconjugates, enabling the generation of gold nanoparticles by laser ablation and their in situ conjugation with any biomolecule bearing an electron donating function (e.g., thiolated oligonucleotides) is established. The integrity of oligonucleotides after conjugation and the stability of bioconjugates in physiological media are investigated. Their size is tailorable via process parameters. This rapid and universal method may provide biochemists with various nanoparticle-bioconjugates for screening the often unpredictable structure,function relationship. [source]

Multiple Functionalities of Polyelectrolyte Multilayer Films: New Biomedical Applications

ADVANCED MATERIALS, Issue 4 2010
Thomas Boudou
Abstract The design of advanced functional materials with nanometer- and micrometer-scale control over their properties is of considerable interest for both fundamental and applied studies because of the many potential applications for these materials in the fields of biomedical materials, tissue engineering, and regenerative medicine. The layer-by-layer deposition technique introduced in the early 1990s by Decher, Moehwald, and Lvov is a versatile technique, which has attracted an increasing number of researchers in recent years due to its wide range of advantages for biomedical applications: ease of preparation under "mild" conditions compatible with physiological media, capability of incorporating bioactive molecules, extra-cellular matrix components and biopolymers in the films, tunable mechanical properties, and spatio-temporal control over film organization. The last few years have seen a significant increase in reports exploring the possibilities offered by diffusing molecules into films to control their internal structures or design "reservoirs," as well as control their mechanical properties. Such properties, associated with the chemical properties of films, are particularly important for designing biomedical devices that contain bioactive molecules. In this review, we highlight recent work on designing and controlling film properties at the nanometer and micrometer scales with a view to developing new biomaterial coatings, tissue engineered constructs that could mimic in vivo cellular microenvironments, and stem cell "niches." [source]

Topographical and Wettability Effects of Post-Discharge Plasma Treatments on Macroporous Polystyrene-Divinylbenzene Solid Foams

PLASMA PROCESSES AND POLYMERS, Issue 10 2009
Cristina Canal
Abstract The aim of this study was to evaluate the morphological characteristics and wetting properties of polystyrene-divinylbenzene (PS-DVB) solid foams and their modification through post-discharge plasmas. The low-density solid foams are mainly macroporous, but show a small fraction of mesopores; their characterization revealed differences in topography between the smoother surface and the rougher bulk, while from the chemical point of view both regions of the PS-DVB solid foams are hydrophobic. The macroporous structure of these materials with high pore volume makes them interesting for the design of new drug delivery systems, but some active principles and the physiological media are hydrophilic; therefore, it would be of interest to modify the wettability of the materials via post-discharge plasma treatments. [source]

Influence of cigarette smoking on spermatozoa via seminal plasma

ANDROLOGIA, Issue 4 2005
M. Arabi
Summary Numerous investigations have been conducted on the relationship between cigarette smoking and male infertility, however, the exact molecular mechanisms are not well understood in most of the cases. Few studies have indicated the direct effect of seminal plasma (SP) [in different dilutions with phosphate buffer solution (PBS)] from smokers (SM) on the sperm functional parameters from nonsmokers (non-SM). The aim of this study was to provide evidence that cigarette smoking affects male fertility via altering the sperm quality. Our results indicated that exposure of spermatozoa from the non-SM to the SP from the SM yielded a significant reduction in the sperm motility and acrosome reaction and an elevation in the amount of malondialdehyde (MDA), in a certain time course. Exposure of spermatozoa from the SM to the SP from the non-SM or with PBS resulted in the nonsignificant improvement in the altered sperm functional parameters indicating removal of SM's SP and then subsequent reconstitution with physiological media could be of clinical significance in the various assisted reproductive technologies applied for SM. However, the detrimental effect of SM's SP on non-SM's spermatozoa was prominent. In addition, as spermatozoa in SM's SP are susceptible to peroxidative damages, men with such cells who wish to have children should especially benefit from quitting smoking. [source]