Pertinent Information (pertinent + information)

Distribution by Scientific Domains


Selected Abstracts


Use of the Bispectral Index monitor to aid titration of propofol during a drug-assisted interview

PEDIATRIC ANESTHESIA, Issue 2 2001
Greta M. Palmer MB
We report two drug-assisted interviews with propofol in an 18-year-old with the diagnosis of Complex Regional Pain Syndrome type 1. We describe difficulty in titration of propofol in the first interview. Consequently, in the second interview, the Bispectral Index (BIS) monitor was applied to assist adjustment of the propofol infusion. This facilitated the achievement of a prolonged sedative-hypnotic state for a successful neuropsychological evaluation. Pertinent information was obtained from this patient. However, the role of drug-assisted interviews as a technique needs to be further elucidated. [source]


Feline diarrhoea associated with Tritrichomonas cf. foetus and Giardia co-infection in an Australian cattery

AUSTRALIAN VETERINARY JOURNAL, Issue 11 2008
SA Bissett
A 10-week-old female Ocicat was presented at a primary care feline veterinary practice for failure to thrive and diarrhoea. Numerous trophozoites, atypical for Giardia sp., were detected on a direct faecal examination, in addition to Giardia cysts. Although the failure to thrive and diarrhoea resolved following treatment for giardiasis, further diagnostic tests performed on faecal specimens from the kitten and 15 other Ocicats from the same cattery, including culture of trophozoites in In PouchÔ medium, PCR testing and molecular sequencing of PCR amplicons, confirmed infection with Tritrichomonas cf. foetus. This is the first report in Australia of feline trichomoniasis, which appears to be an emerging infectious disease of cats. Pertinent information regarding the clinical features, diagnosis, therapy, and potential source of feline trichomoniasis within Australia are discussed. [source]


Neurophysiology of hunger and satiety

DEVELOPMENTAL DISABILITIES RESEARCH REVIEW, Issue 2 2008
Pauline M. Smith
Abstract Hunger is defined as a strong desire or need for food while satiety is the condition of being full or gratified. The maintenance of energy homeostasis requires a balance between energy intake and energy expenditure. The regulation of food intake is a complex behavior. It requires discrete nuclei within the central nervous system (CNS) to detect signals from the periphery regarding metabolic status, process and integrate this information in a coordinated manner and to provide appropriate responses to ensure that the individual does not enter a state of positive or negative energy balance. This review of hunger and satiety will examine the CNS circuitries involved in the control of energy homeostasis as well as signals from the periphery, both hormonal and neural, that convey pertinent information regarding short-term and long-term energy status of the individual. © 2008 Wiley-Liss, Inc. Dev Disabil Res Rev 2008;14:96,104. [source]


Local Government Accounting Standard-setting in Australia: Did Constituents Participate?

FINANCIAL ACCOUNTABILITY & MANAGEMENT, Issue 4 2000
Christine Ryan
The Public Sector Accounting Standards Board (PSASB) has developed accounting standards for the public sector in Australia. A procedural ,due process' has been developed to protect the openness, neutrality and independence of Australian standard-setting both in the private and public sectors. Prior research into constituent participation in the ,due process' for specific cases in the public sector has raised doubts as to whether the ,due process' operated in an open, neutral and independent manner. It has found that account preparers were under-represented in their responses and used less sophisticated lobbying strategies than other respondents. The research also concluded that some constituents had favourable access to the ,due process', and that standard setters did not receive all pertinent information from constituents. This paper examines constituent participation in the ,due process' for the first public sector accounting standard, that for local government (AAS 27). The submissions made on the exposure draft preceding the standard ,ED 50, have been analysed using content analysis. The findings suggest that account preparers were well-represented in their responses and adopted the lobbying strategy of weighting their responses with supporting argument for the most controversial issues. Contrary to prior research, the paper concludes that in the case of ED 50 there is no evidence that the ,due process' failed to operate in an open and neutral manner. [source]


Surgical treatment of migraine headaches.

HEADACHE, Issue 3 2003
B Guyuron
Plast Reconstr Surg. 2002 Jun;109(7):2183-2189 This prospective study was conducted to investigate the role of removal of corrugator supercilii muscles, transection of the zygomaticotemporal branch of the trigeminal nerve, and temple soft-tissue repositioning in the treatment of migraine headaches. Using the criteria set forth by the International Headache Society, the research team's neurologist evaluated patients with moderate to severe migraine headaches, to confirm the diagnosis. Subsequently, the patients completed a comprehensive migraine headaches questionnaire and the team's plastic surgeon injected 25 units of botulinum toxin type A (Botox) into each corrugator supercilii muscle. The patients were asked to maintain an accurate diary of their migraine headaches and to complete a monthly questionnaire documenting pertinent information related to their headaches. Patients in whom the injection of Botox resulted in complete elimination of the migraine headaches then underwent resection of the corrugator supercilii muscles. Those who experienced only significant improvement underwent transection of the zygomaticotemporal branch of the trigeminal nerve with repositioning of the temple soft tissues, in addition to removal of the corrugator supercilii muscles. Once again, patients kept a detailed postoperative record of their headaches. Of the 29 patients included in the study, 24 were women and five were men, with an average age of 44.9 years (range, 24 to 63 years). Twenty-four of 29 patients (82.8 percent, p < 0.001) reported a positive response to the injection of Botox, 16 (55.2 percent, p < 0.001) observed complete elimination, eight (27.6 percent, p < 0.04) experienced significant improvement (at least 50 percent reduction in intensity or severity), and five (17.2 percent, not significant) did not notice a change in their migraine headaches. Twenty-two of the 24 patients who had a favorable response to the injection of Botox underwent surgery, and 21 (95.5 percent, p < 0.001) observed a postoperative improvement. Ten patients (45.5 percent, p < 0.01) reported elimination of migraine headaches and 11 patients (50.0 percent, p < 0.004) noted a considerable improvement. For the entire surgical group, the average intensity of the migraine headaches reduced from 8.9 to 4.1 on an analogue scale of 1 to 10, and the frequency of migraine headaches changed from an average of 5.2 per month to an average of 0.8 per month. For the group who only experienced an improvement, the intensity fell from 9.0 to 7.5 and the frequency was reduced from 5.6 to 1.0 per month. Only one patient (4.5 percent, not significant) did not notice any change. The follow-up ranged from 222 to 494 days, the average being 347 days. In conclusion, this study confirms the value of surgical treatment of migraine headaches, inasmuch as 21 of 22 patients benefited significantly from the surgery. It is also evident that injection of Botox is an extremely reliable predictor of surgical outcome. Comment: Many small placebo-controlled studies and much anecdotal literature suggests that botulinum toxin may be effective in prevention of migraine, perhaps to the same extent as conventional prophylactic treatment. Larger, randomized clinical trials are underway to resolve this issue. In the meantime, those who believe in the effectiveness of botulinum toxin prophylaxis argue about how it works, that is whether its antinociceptive properties are due to peripheral effects, central or presynaptic effects, or both. Dr. Guyuron's group favors the idea that botulinum toxin interrupts a reflex arc between the central nervous system (CNS) and peripheral musculature, and that after establishing efficacy by low dose botulinum injection in the corrugator supercilii muscles, surgical resection of these muscles results in prolonged and effective prophylaxis. The idea is radical but intriguing and should not be dismissed out of hand. However, a trial is necessary in which both the botulinum toxin injections are blinded with vehicle, and the study of the surgery involves a sham surgery control group with extended long-term follow-up, before these forms of prophylaxis can be recommended to patients. SJT [source]


Cities as agents of global change

INTERNATIONAL JOURNAL OF CLIMATOLOGY, Issue 14 2007
Gerald Mills
Abstract Cities, as places where human activities are concentrated, are frequently cited as the chief causes of, and solutions to, anthropogenic global change. In this article, I review the climatology literature that examines the relationship between cities and atmospheric changes at all scales. Despite the volume of literature on this theme, there is little overall coherence. In part, this is a result of the varying operational definitions of the city and the difficulty in obtaining pertinent information. Rather than attempt to provide a comprehensive review of the literature that focuses on cities and global change, this article categorises published research on the relationship between urban areas and climate changes at all scales into common themes. Copyright © 2007 Royal Meteorological Society [source]


Health of the nation: an individual or a corporate social responsibility?

JOURNAL OF PUBLIC AFFAIRS, Issue 2 2007
A preliminary investigation into consumer perceptions
Britain is increasingly mirroring a number of nations in terms of the continued growth in prevailing levels of illnesses related potentially to human food consumption. As this issue fast becomes global, the question of whose responsibility it is, has come to the forefront of the debate. Other groups, apart from the Governments with direct involvement in this crisis are the Consumers and the Marketers. Using the food industry as the basis, the study primarily focuses on the consumers' perceptions of the nature and the extent of the problem. To investigate, three products used in the study are placed on a continuum; Chocolates represent one end and Genetically manufactured foods the other. Fast foods are represented in the middle. This framework highlights variations in consumer perceptions based on product differences: manufacturers have been held responsible for the provision of pertinent information in the case of genetically manufactured products; in the context of fast foods and Confectionery both manufacturers and consumers have been seen as responsible for consumers' existing consumption patterns. Copyright © 2007 John Wiley & Sons, Ltd. [source]


The role of gastroesophageal reflux disease in asthma

JOURNAL OF THE AMERICAN ACADEMY OF NURSE PRACTITIONERS, Issue 5 2008
CCRN (Family Nurse Practitioner Student), Sandra Huggins RN
Abstract Purpose: To emphasize the relationship between gastroesophageal reflux disease (GERD) and asthma symptoms or exacerbations. Data sources: Selective review of the scientific literature. Conclusions: Although studies in recent years have offered insight into the relationship between GERD and asthma symptoms, many nurse practitioners (NPs) fail to recognize atypical GERD symptoms, which may explain difficult-to-treat asthma and exacerbation. It has become evident that patients suffering from persistent asthma display an increased prevalence of GERD. Implications for practice: While there are increasing constraints that limit the provider,patient interaction time, it is imperative that NPs develop keen assessment skills to effectively diagnose and treat asthma symptoms that are a product of GERD. Awareness of the asthma,GERD relationship allows NPs to quickly obtain pertinent information and successfully determine how to efficiently treat symptomatic asthmatic patients. [source]


International Regulations for Automobile Driving and Epilepsy

JOURNAL OF TRAVEL MEDICINE, Issue 1 2000
Winnie W. Ooi
Background: Many patients with epilepsy travel abroad and drive automobiles with the assumption that policies, rules, and regulations on epilepsy and driving are similar to those of their home countries. This paper investigates the driving restrictions and other pertinent information on this issue in foreign countries. Methods: A questionnaire was sent to 231 neurologists (chosen from American neurological and epilepsy societies) from 84 countries and to 230 official (embassies and consulates) representatives of 134 countries asking for the local rules and regulations and their comments on driving and epilepsy. Results: One hundred and sixty-six responses were received from 96 of 134 (72%) countries. One hundred and six neurologists (of 231 queried [46%]) responded. In 16 countries, persons with epilepsy are not permitted to drive. In the remaining countries, these patients must have a seizure-free period of 6 to 36 months. This period varies according to the type of seizure. In five countries, physicians must report the names of these patients to their local authorities. In many countries, the rules and regulations are being reevaluated and changed. Conclusions: Patients with epilepsy who plan to drive overseas are advised to contact local embassies and consulates, well before their trips (and keep records of the communications) to obtain the latest information on the rules and regulations governing the driving of automobiles in those countries. [source]


Exercise-induced hypersensitivity syndromes in recreational and competitive athletes: a PRACTALL consensus report (what the general practitioner should know about sports and allergy)

ALLERGY, Issue 8 2008
L. B. Schwartz
Exercise-induced (EI) hypersensitivity disorders are significant problems for both recreational and competitive athletes. These include EI-asthma, EI-bronchoconstriction, EI-rhinitis, EI-anaphylaxis and EI,urticaria. A group of experts from the European Academy of Allergology and Clinical Immunology and the American Academy of Allergy Asthma and Immunology met to discuss the pathogenesis of these disorders and how to diagnose and treat them, and then to develop a consensus report. Key words (exercise with asthma, bronchoconstriction, rhinitis, urticaria or anaphylaxis) were used to search Medline, the Cochrane database and related websites through February 2008 to obtain pertinent information which, along with personal reference databases and institutional experience with these disorders, were used to develop this report. The goal is to provide physicians with guidance in the diagnosis, understanding and management of EI-hypersensitivity disorders to enable their patients to safely return to exercise-related activities. [source]


Process improvement evaluation approach using flow diagrams

QUALITY ASSURANCE JOURNAL, Issue 3 2006
Paul C. Constant Jr.
Abstract Maintaining company processes will afford optimum operation and enhance the company's quality management system. A vital part of maintaining processes is their periodic evaluation. An important part of the monitoring and evaluation process is the flow diagram. A detailed flow diagram is an important tool that affords ease in visualizing the total process and is an aid in locating problem areas. The evaluation of a process is broken down into 15 steps. These steps cover gathering pertinent information, such as problem symptoms from knowledgeable sources and carrying these through their route to potential problem areas to the problems, potential causes, and the root cause of the problem. Knowing the problems brings about the need to assess their impact on the process operation as well as what changes to the process are needed and what impact these changes will have on the product , its improved quality and cost , and other vital information, such as, production rate increase, competition status, and company image. With this information, the appropriate changes are made according to a process change action plan. The plan is executed, and the process is continuously monitored according to a monitoring and evaluation plan. The paper ends with conclusions. Copyright © 2006 John Wiley & Sons, Ltd. [source]


Developing recovery and monitoring strategies for the endemic Mount Graham red squirrels (Tamiasciurus hudsonicus grahamensis) in Arizona

ANIMAL CONSERVATION, Issue 1 2004
Kate E. Buenau
An important challenge in conservation biology is extracting pertinent information from the available data for endangered species. Rarely do we have enough information to precisely determine an organism's risk of extinction and other factors that affect its management. How, then, can we use limited information to make responsible conservation decisions on controversial species such as the Mount Graham red squirrel? We used several analytical approaches to examine 15 years of abundance data for the Mount Graham red squirrel in order to propose recovery criteria and to evaluate alternative conservation strategies. We analysed the historical population dynamics using a diffusion approximation model and showed that the main threat to the population was not the overall growth rate (which may well be greater than 1) but rather the wide range of variation in annual growth rates. We used information on the distribution of growth rates and abundance to classify the species as threatened under the Endangered Species Act (ESA). We then presented a simple demographic model to examine the effects of proportional changes in vital rates on the population growth rate (,). The elasticity values obtained for Mount Graham red squirrels indicate that the population is far more sensitive to changes in survival rates (particularly adult survival) compared to reproduction. Our analyses suggest that management should focus on refining monitoring techniques, reducing sources of variability, improving the survival of adult animals and filling the gaps in the currently available data. [source]


Unsolved problems in observational astronomy.

ASTRONOMISCHE NACHRICHTEN, Issue 6-8 2004

Abstract The existence of rapidly slewing robotic telescopes and fast alert distribution via the Internet is revolutionizing our capability to study the physics of fast astrophysical transients. But the salient challenge that optical time domain surveys must conquer is mining the torrent of data to recognize important transients in a scene full of normal variations. Humans simply do not have the attention span, memory, or reaction time required to recognize fast transients and rapidly respond. Autonomous robotic instrumentation with the ability to extract pertinent information from the data stream in real time will therefore be essential for recognizing transients and commanding rapid follow-up observations while the ephemeral behavior is still present. Here we discuss how the development and integration of three technologies: (1) robotic telescope networks; (2) machine learning; and (3) advanced database technology, can enable the construction of smart robotic telescopes, which we loosely call "thinking" telescopes, capable of mining the sky in real time. (© 2004 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source]


Oncogenes in thyroid cancer

CLINICAL OTOLARYNGOLOGY, Issue 5 2003
D.S. Kim
There have been significant advances in our understanding of carcinogenesis at the molecular level over the last 25 years. Oncogenes are of major interest as part of our search for knowledge surrounding the aetiology of cancer. There are several oncogenes associated with thyroid cancer. Detailed investigation of the nature and function of these tumour genes has provided important insights into both the tumour biology and the complex biochemical pathways of normal cellular functioning. Our knowledge of oncogene biology offers the hope of better diagnostic, therapeutic and prognostic modalities in our fight against this and other common cancers. Development of specific thyroid tumour markers and gene therapy is now a realistic prospect to supplement our present armamentarium of surgery and radiotherapy. This review aims to outline the pertinent information gained so far from studies of these oncogenes and provides both clinical relevance and fuel for further interest amongst the ENT thyroid community in this exciting area of research. [source]