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Pyridine Derivatives (pyridine + derivative)
Selected AbstractsWide Blue Phase Range in a Hydrogen-Bonded Self-Assembled Complex of Chiral Fluoro-Substituted Benzoic Acid and Pyridine DerivativeADVANCED MATERIALS, Issue 20 2009Wanli He A blue phase with a broad temperature range of about 23.0 °C is easily achieved in a hydrogen-bonded self-assembled complex of chiral fluoro-substituted benzoic acid and pyridine derivative. The success in extending the temperature of blue phase indicates that the hydrogen-bonded self-assembly is a promising new approach to broaden the temperature range of blue phases and to investigate the mystery of blue phases. [source] Synthesis of Multiaryl-Substituted Pyridine Derivatives and Applications in Non-doped Deep-Blue OLEDs as Electron-Transporting Layer with High Hole-Blocking AbilityADVANCED MATERIALS, Issue 4 2010Na Li Two multiaryl-substituted pyridine derivatives, applied as electron transport materials (ETMs; see figure) with good hole- blocking ability in high-performance deep-blue OLEDs, are characterized. The maximum current efficiencies of the devices based on the new compounds are over 70% higher than previously reported devices using traditional ETMs instead. The CIE coordinates of the devices based on the new compounds are close to the NTSC standards of (0.14, 0.08) for blue emission. [source] Highly Enantioselective Hydrogenation of Quinoline and Pyridine Derivatives with Iridium-(P-Phos) CatalystADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 6 2010Wei-Jun Tang Abstract The use of a chiral iridium catalyst generated in situ from the (cyclooctadiene)iridium chloride dimer, [Ir(COD)Cl]2, the P-Phos ligand [4,4,-bis(diphenylphosphino)-2,2,,6,6,-tetramethoxy-3,3,-bipyridine] and iodine (I2) for the asymmetric hydrogenation of 2,6-substituted quinolines and trisubstituted pyridines [2-substituted 7,8-dihydroquinolin-5(6H)-one derivatives] is reported. The catalyst worked efficiently to hydrogenate a series of quinoline derivatives to provide chiral 1,2,3,4-tetrahydroquinolines in high yields and up to 96% ee. The hydrogenation was carried out at high S/C (substrate to catalyst) ratios of 2000,50000, reaching up to 4000,h,1 TOF (turnover frequency) and up to 43000 TON (turnover number). The catalytic activity is found to be additive-controlled. At low catalyst loadings, decreasing the amount of additive I2 was necessary to maintain the good conversion. The same catalyst system could also enantioselectively hydrogenate trisubstituted pyridines, affording the chiral hexahydroquinolinone derivatives in nearly quantitative yields and up to 99% ee. Interestingly, increasing the amount of I2 favored high reactivity and enantioselectivity in this case. The high efficacy and enantioselectivity enable the present catalyst system of high practical potential. [source] Synthesis of Substituted Pyridine Derivatives via the Ruthenium-Catalyzed Cycloisomerization of 3-Azadienynes.CHEMINFORM, Issue 31 2006Mohammad Movassaghi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis of Substituted Pyridine Derivatives via the Ruthenium-Catalyzed Cycloisomerization of 3-Azadienynes.CHEMINFORM, Issue 31 2006Mohammad Movassaghi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Discovery of 2,3,5-Trisubstituted Pyridine Derivatives as Potent Akt1 and Akt2 Dual Inhibitors.CHEMINFORM, Issue 25 2005Zhijian Zhao Abstract For Abstract see ChemInform Abstract in Full Text. [source] One-Pot Synthesis of Pyridine Derivatives via Diels,Alder Reactions of 2,4-Dimethyl-5-methoxyoxazole.CHEMINFORM, Issue 22 2005Samir Bondock Abstract For Abstract see ChemInform Abstract in Full Text. [source] Regioselective Photocycloaddition of Pyridine Derivatives to Electron-Rich Alkenes.CHEMINFORM, Issue 27 2003Masami Sakamoto Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Green Chemoselective Synthesis of Thiazolo[3,2-a]pyridine Derivatives and Evaluation of Their Antioxidant and Cytotoxic Activities.CHEMINFORM, Issue 8 2010Feng Shi Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Efficient Method for Synthesis of Pyrano[3,2-c]pyridine Derivatives under Microwave Irradiation.CHEMINFORM, Issue 6 2010Shu-Liang Wang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: One-Pot Synthesis of Some Novel 2,4-Diaryl-6-(5-methyl-1-p-tolyl-1H-1,2,3-triazol-4-yl)pyridine Derivatives.CHEMINFORM, Issue 42 2009Zi-Ping Cao Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Unexpected Reaction of Cyanothioacetamide: Novel Preparation of Pyrazolo[3,4-b]pyridine Derivatives under MWI.CHEMINFORM, Issue 46 2008Xue Sen Fan Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: A Novel and Green Method for the Synthesis of Indeno[2,1-c]pyridine Derivatives in Ionic Liquid Catalyzed by Malononitrile.CHEMINFORM, Issue 39 2008Xiang-Shan Wang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Reactions with Dimethylformamide-Dimethylacetal: Synthesis and Reactions of Several New Pyridine and Pyrazolo[3,4-b]pyridine Derivatives.CHEMINFORM, Issue 38 2007Mohamed A. A. Elneairy Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] One-Pot Synthesis of 3-Bromoimidazo[1,2-a]pyridine Derivatives Accompanied by Dimethyl Sulfoxide Oxidation.CHEMINFORM, Issue 32 2006Tomikazu Kawano Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Titanium(IV) Chloride Promoted Syntheses of New Imidazo[1,2-a]pyridine Derivatives under Microwave Conditions.CHEMINFORM, Issue 20 2006Lisheng Cai Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Pyrazoles as Building Blocks in Heterocyclic Synthesis: Synthesis of Some New Substituted 1-Triazinylpyrazolo[3,4-d]pyrimidine and 1-Triazinylpyrazolo[3,4-b]pyridine Derivatives.CHEMINFORM, Issue 50 2005A.-F. A. Harb No abstract is available for this article. [source] Halogenation of 2-Unsubstituted and 2-Methylimidazo[4,5-b]pyridine Derivatives.CHEMINFORM, Issue 46 2005Yu. M. Yutilov Abstract For Abstract see ChemInform Abstract in Full Text. [source] Synthesis of 6,6-Difluorocyclopropa[b]furo[2,3-c]pyrrole and 7-Fluorofuro[3,2-c]pyridine Derivatives via 1,5-Electrocyclization of Carbene-Derived Azomethine Ylides.CHEMINFORM, Issue 35 2005Igor V. Voznyi Abstract For Abstract see ChemInform Abstract in Full Text. [source] Ipso- or Cine-Substitutions of 6-Haloimidazo[1,2-a]pyridine Derivatives with Different Azoles Depending on the Reaction Conditions.CHEMINFORM, Issue 48 2003Cecile Enguehard Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Combinatorial Synthesis of 5-Aryl-[1,2,4]-triazolo-[1,5-a]-pyridine Derivatives as Potential Inhibitors of the Adenosine 2A Receptor.CHEMINFORM, Issue 15 2002Matthias Nettekoven Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis of Substituted Oxazolo[4,5-b]pyridine Derivatives.CHEMINFORM, Issue 48 2001Valerie Grumel Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] An Electroanalytical Investigation on the Redox Properties of Calcium Antagonist DihydropyridinesELECTROANALYSIS, Issue 10 2003Rosanna Toniolo Abstract The antioxidant capacity of some calcium antagonists and one calcium agonist 1,4-dihydropyridines (DHPs) was evaluated by a competitive kinetic procedure. With the exception of Amlodipine, all the calcium antagonist DHPs display an unambiguous antioxidant capacity, while for the calcium agonist DHP (Bay K 8644) no measurable reactivity towards peroxyl radicals could be detected. The finding was corroborated by an electroanalytical investigation of the redox properties of DHPs compounds to get an insight about both the thermodynamic constraints of their oxidation process and reaction pattern. The oxidation potentials decrease with both antioxidant capacity and increasing basic character, thus suggesting the relevance of the electron density on the DHP ring. For all the compounds investigated, the overall oxidation process takes place through a primary one-electron step accompanied by a fast proton release and the formation of a neutral radical undergoing a second much easier one-electron step. The protonated form of the parent pyridine derivative is thus generated as the final product. This pattern is relevant for the antioxidant effect, since the radical intermediate is much more prone to be oxidized than to be reduced, thus fully preventing the propagation of the oxidative chain reaction. In the case of calcium antagonist DHPs, the above release of protons complicates the overall oxidation process by introducing a parasitic side reaction where a coupling between protons and the starting species takes place. This DHP self-protonation subtracts part of the original species from the electrode process because the parent cationic species is no longer electroactive. Conversely, the calcium agonist DHP, which is more difficult to be oxidized, turned out to be such a weak base as to be unable to undergo the self-protonation reaction. The combined effect of oxidation potentials and proton binding capacity of DHPs is a key element for the redox transition, which could support their antioxidant effect and should be considered to some extent in accounting for the calcium antagonist vs calcium agonist effect. [source] A Simple Fluorescent Ion-Pair Binding Host that Acts as an "If-Then" Logic GateEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 26 2009Sara Jane Dickson Abstract A donor-acceptor-type carbazole pyridine derivative behaves as an "if-then" fluorescent molecular logic gate using chemical inputs in the form of copper(II) cations and nitrate anions. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source] Benzylideneruthenium Complexes Bearing Pyridine-Based Ligands and Their Influence on the Formation of Mono- or Bis(pyridine) ComplexesEUROPEAN JOURNAL OF INORGANIC CHEMISTRY, Issue 34 2007Wen-Zhen Zhang Abstract Benzylideneruthenium complexes bearing the N-heterocyclic carbene (NHC) ligand 1,3-bis(2,6-dimethylphenyl)-4,5-dihydroimidazol-2-ylidene (H2IMe) and one or two pyridine-based ligands have been prepared by treating [RuCl2(=CHPh)(H2IMe)(PPh3)] with the corresponding pyridine derivative. X-ray crystallographic and mass spectrometric evidence is used to investigate the interconversion between mono- and bis(pyridine) complexes and the influence of the pyridine ligand on the formation of these complexes. The catalytic activity of these complexes has been tested in the ring-closing metathesis (RCM) reaction of diallylmalononitrile and the cross metathesis (CM) reaction of acrylonitrile with terminal olefins.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source] Wide Blue Phase Range in a Hydrogen-Bonded Self-Assembled Complex of Chiral Fluoro-Substituted Benzoic Acid and Pyridine DerivativeADVANCED MATERIALS, Issue 20 2009Wanli He A blue phase with a broad temperature range of about 23.0 °C is easily achieved in a hydrogen-bonded self-assembled complex of chiral fluoro-substituted benzoic acid and pyridine derivative. The success in extending the temperature of blue phase indicates that the hydrogen-bonded self-assembly is a promising new approach to broaden the temperature range of blue phases and to investigate the mystery of blue phases. [source] ,-Oxoanilides in heterocyclic synthesis: An expeditious synthesis of new polyfunctionally substituted pyridine and pyrazole derivativesJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 6 2008A. M. Hussein 3-Oxo- N -{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}butanamide 3 was condensed with (DMF-DMA) in refluxing dry dioxane to yield branched structure 4 not its linear isomeric 5. Compound 4 readily reacted with active methylene to yield compounds 8a-c, 14, 17 and 20 respectively. Also enaminone 4 reacted with phenyl hydrazine giving 24 and 25. In contrast, when compound 4 reacted with hydrazine hydrate in the same experimental conditions pyrazole derivative 27 was obtained. Furthermore, condensation of anilide 3 with triethylorthoformate in refluxing acetic anhydride afforded the ethoxy methylene derivative 28. On the other hand, compound 28 was reacted with active methylene reagents, and hydrazines to afford the products identical in all respects (mp., mixed mp., and spectral data) with those corresponding to compounds 6-27 respectively. Similarly, compound 3 was reacted with hydrazine hydrate to afford the reaction product 29. Also, compound 3 reacted with cyanoacetamide in refluxing ethanolic pipridine solution to yield the pyridine derivative 30. Finally, 3 reacted with hydroxylamine hydrochloride in refluxing ethanol/sodium acetate solution to yield the acyclic oxime derivative 31. [source] Synthesis of Metal,(Pentadentate-Salen) Complexes: Asymmetric Epoxidation with Aqueous Hydrogen Peroxide and Asymmetric Cyclopropanation (salenH2: N,N, -bis(salicylidene)ethylene-1,2-diamine)CHEMISTRY - A EUROPEAN JOURNAL, Issue 17 2007Hiroaki Shitama Abstract It is known that the rates and stereochemical outcomes of epoxidations and cyclopropanations using a metallosalen (salenH2: N,N, -bis(salicylidene)ethylene-1,2-diamine) complex as catalyst are affected by a trans effect of the apical ligand of the complex. By taking into consideration this trans effect, we have synthesized optically active pentadentate salen ligands bearing an imidazole or pyridine derivative as the fifth coordinating group, and have prepared the corresponding manganese(III) and cobalt(II) complexes, in which the fifth ligand is expected to intramolecularly coordinate to the metal center and exert a trans effect. Indeed, high enantioselectivity has been achieved in epoxidations using aqueous hydrogen peroxide as the terminal oxidant and in cyclopropanations with these complexes as catalysts. In general, metallosalen-catalyzed reactions have been carried out in the presence of an excess of a donor ligand; however, the present reactions do not need the addition of any extra donor ligand. [source] Preparation and Recognition Study on the Peptides in Aqueous Media of Poly(pyridine derivative- co -acrylamide)CHINESE JOURNAL OF CHEMISTRY, Issue 5 2008Jian-Xin ZHAO Abstract Three copolymers (bearing metal ion coordinated sites) P1, P2 and P3 were synthesized and their recognition behavior on predetermined peptide sequences was studied by isothermal titration calorimetry. [source] Synthesis of novel substituted pyridine derivatives from 3,5-diacetyl-2,6-dimethylpyridineHETEROATOM CHEMISTRY, Issue 3 2009Jun Zhang A series of novel (1-acetyl-5-aryl-4,5-dihydro)-1H-pyrazole substituted pyridine derivatives and poly substituted [2,3,-bipyridine]-5-carbonitrile derivatives were synthesized from 3,5-diacetyl-2,6-dimethylpyridine. The structures of two typical 3,5-bis[1-acetyl-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-2,6-dimethylpyridines [3b(1) and 3b(2)] were confirmed by X-ray diffraction analysis. © 2009 Wiley Periodicals, Inc. Heteroatom Chem 20:123,130, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20522 [source] | ||||||||||||||||||||||||||||