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Selected AbstractsEvaluation of tooth-fragment reattachment: a clinical and laboratory studyDENTAL TRAUMATOLOGY, Issue 4 2010Yucel Yilmaz Materials and Methods:, The clinical study was conducted on 43 fractured incisors: 22 uncomplicated crown fractures (Group A) and 21 complicated crown fractures (Group B). The 43 incisal fragments: 23 were kept dry for 47 h and 20 were kept wet for 24 h by the patients before they were reattached. The fragments were kept in 0.9% saline solution for 30 min before reattachment. The fragments in Group A were reattached using a dentin bonding agent, a flowable and a hybrid resin composite, whereas the fragments in Group B were reattached to the tooth remnant after a pulpotomy was performed. The laboratory study was conducted on 56 extracted incisors. Teeth were divided equally into four groups: Group I , Uncomplicated crown fracture + wet medium; Group II , Uncomplicated crown fracture + dry medium; Group III , Complicated crown fracture + wet medium, and Group IV , Complicated crown fracture + dry medium. The fragments were then reattached in a manner that was similar to that used in the clinical study. The restored teeth were then re-fractured. All data were analyzed statistically. Results: In the clinical study, the restored teeth were followed up for 2 years. Neither the type of trauma nor the storage medium had any significant effect on the survival, color, and bond strength of the restored teeth when assessed in the clinical and laboratory study. The color disharmony that was encountered initially in restored teeth resolved significantly on its own accord within 12 months after reattachment of the fragment. Conclusion: Fragment reattachment can be used to treat fractured teeth successfully in children and adolescents. [source] What and How of North American Lutheran PreachingDIALOG, Issue 4 2004Thomas G. Rogers Abstract:, This article suggests that an emphasis on how to preach, evidenced in the New Homiletic, can assist preachers in struggling with questions of what to preach. The narrative model of "problem","solution","what now?" has potential homiletical ties to Law (2nd use), Gospel, Law (3rd use) theology. Since preaching 3rd use of the Law can lead to a kind of works righteousness for hearers of such sermons, strategies are offered for dealing with preaching challenge. Preachers can put challenge before their hearers as a noun rather than as a verb; they can preach challenge as identification or questioning rather than as something hearers must do of their own accord. [source] Discontinuation of prophylactic therapy in severe haemophilia: incidence and effects on outcomeHAEMOPHILIA, Issue 6 2001K. Fischer A cohort study was performed to assess adherence to early prophylactic therapy and its effects on outcome in 49 patients with severe haemophilia born 1970,1980. Median age at start of prophylaxis was 5.5 years. The majority (69%) of patients interrupted prophylactic treatment one or more times of their own accord (median total interruption 2.2 years). Patients who discontinued prophylaxis at any point tended to have more arthropathy as measured by the Pettersson scale (median 8 points versus 4 points). One-third of these patients interrupted prophylaxis for longer periods and had permanently stopped taking prophylaxis at a mean age of 20.1 years (mean ± SD duration 4.1 ± 4 years) and consequently experienced 5.4 ± 3.4) joint bleeds per year. This subgroup could be identified by a predictive score based on age at start of prophylaxis, weekly dose of prophylaxis, and joint bleed frequency on prophylaxis. In conclusion, while on prophylaxis, more than two-thirds of patients with severe haemophilia try to discontinue treatment, resulting in slightly more arthropathy. One-third of these patients permanently discontinue prophylaxis in adulthood, while maintaining a low number of joint bleeds. [source] Cytokines and Cognition,The Case for A Head-to-Toe Inflammatory ParadigmJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 12 2002Craig J. Wilson MBBS The brain is not only immunologically active of its own accord, but also has complex peripheral immune interactions. Given the central role of cytokines in neuroimmmunoendocrine processes, it is hypothesized that these molecules influence cognition via diverse mechanisms. Peripheral cytokines penetrate the blood-brain barrier directly via active transport mechanisms or indirectly via vagal nerve stimulation. Peripheral administration of certain cytokines as biological response modifiers produces adverse cognitive effects in animals and humans. There is abundant evidence that inflammatory mechanisms within the central nervous system (CNS) contribute to cognitive impairment via cytokine-mediated interactions between neurons and glial cells. Cytokines mediate cellular mechanisms subserving cognition (e.g., cholinergic and dopaminergic pathways) and can modulate neuronal and glial cell function to facilitate neuronal regeneration or neurodegeneration. As such, there is a growing appreciation of the role of cytokine-mediated inflammatory processes in neurodegenerative diseases such as Alzheimer's disease and vascular dementia. Consistent with their involvement as mediators of bidirectional communication between the CNS and the peripheral immune system, cytokines play a key role in the hypothalamic-pituitary-adrenal axis activation seen in stress and depression. In addition, complex cognitive systems such as those that underlie religious beliefs, can modulate the effects of stress on the immune system. Indirect means by which peripheral or central cytokine dysregulation could affect cognition include impaired sleep regulation, micronutrient deficiency induced by appetite suppression, and an array of endocrine interactions. Given the multiple levels at which cytokines are capable of influencing cognition it is plausible that peripheral cytokine dysregulation with advancing age interacts with cognitive aging. [source] Verlaine's La bonne chanson and Romances sans parolesORBIS LITERARUM, Issue 5 2006The Vortical Link In Verlaine's La bonne chanson, the path to the lady involves centripetal circling, proceeding by degrees, toward an ever closer encounter, in hopes of achieving synthesis with her at the stillpoint of a vortex. Two episodes, located like elliptical dual centers, result in two outcomes: the first, a sudden, centrifugal reversal flinging him violently away, signifying the lady's rejection; the second, an apparently successful but short-lived fusion, as the poet's measured centrifugal withdrawing, this time of his own accord, portrays. By the time Romances sans paroles opens, estrangement from the lady has increased, but a harmonious intimacy has developed between the poet and a male companion, and the poet's bisexuality is reflected by various gender relations and shifts. His open avowal of a homosexual affair is a shock that upsets the delicate balance between conflicting desires that had been, until now, precariously maintained, resulting in the violent, vertiginous vortex that tears things apart. Although the vortex is, as phenomenon and symbol, reversible, whirling centripetally toward a calm union at the center or centrifugally away toward the furious chaos at the periphery, it is the destructive centrifuge that prevails in these works, ending all tensions and conflicts by annihilating them. [source] |