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Other Qualities (other + quality)

Distribution by Scientific Domains

Life Sciences	50%

Selected Abstracts

Power and robustness of linkage tests for quantitative traits in general pedigrees

GENETIC EPIDEMIOLOGY, Issue 1 2005
Wei-Min Chen
Abstract There are numerous statistical methods for quantitative trait linkage analysis in human studies. An ideal such method would have high power to detect genetic loci contributing to the trait, would be robust to non-normality in the phenotype distribution, would be appropriate for general pedigrees, would allow the incorporation of environmental covariates, and would be appropriate in the presence of selective sampling. We recently described a general framework for quantitative trait linkage analysis, based on generalized estimating equations, for which many current methods are special cases. This procedure is appropriate for general pedigrees and easily accommodates environmental covariates. In this report, we use computer simulations to investigate the power and robustness of a variety of linkage test statistics built upon our general framework. We also propose two novel test statistics that take account of higher moments of the phenotype distribution, in order to accommodate non-normality. These new linkage tests are shown to have high power and to be robust to non-normality. While we have not yet examined the performance of our procedures in the context of selective sampling via computer simulations, the proposed tests satisfy all of the other qualities of an ideal quantitative trait linkage analysis method. Genet. Epidemiol. © 2004 Wiley-Liss, Inc. [source]

Teaching gross anatomy using living tissue

CLINICAL ANATOMY, Issue 2 2002
D.S. Hubbell
Abstract Embalmed cadaver tissues and organs that are dissected in gross anatomy laboratories lack many characteristics of fresh or living tissues. The purpose of this study was to assess the educational value of allowing first-year medical students to experience first-hand the color, texture, delicacy and other qualities of living porcine tissues and organs that are similar to those of human tissues. Guided by a laboratory protocol, medical students palpated and inspected organs of the opened thorax, abdomen and pelvis of anesthetized pigs on pulmonary ventilators. The learning experience was rated highly by the students as well as by the participating faculty. A further review of the medical students' later experiences at autopsies and in surgical clerkships showed that the living-tissue experience in their gross anatomy course represented a large part of their medical school exposure to unembalmed tissues. Clin. Anat. 15:157,159, 2002. © 2002 Wiley-Liss, Inc. [source]

The effects of Taiwan's National Health Insurance on access and health status of the elderly

HEALTH ECONOMICS, Issue 3 2007
Likwang Chen
Abstract The primary objective of this paper is to evaluate the impact of Taiwan's National Health Insurance program (NHI), established in 1995, on improving elderly access to care and health status. Further, we estimate the extent to which NHI reduces gaps in access and health across income groups. Using data from a longitudinal survey, we adopt a difference-in-difference methodology to estimate the causal effect of Taiwan's NHI. Our results show that Taiwan's NHI has significantly increased utilization of both outpatient and inpatient care among the elderly, and such effects were more salient for people in the low- or middle-income groups. Our findings also reveal that although Taiwan's NHI greatly increased the utilization of both outpatient and inpatient services, this increased utilization of health services did not reduce mortality or lead to better self-perceived general health status for Taiwanese elderly. Measures more sensitive than mortality and self-perceived general health may be necessary for discerning the health effects of NHI. Alternatively, the lack of NHI effects on health may reflect other quality and efficiency problems inherent in the system not yet addressed by NHI. Copyright © 2006 John Wiley & Sons, Ltd. [source]

ISO 14001 EMS standard registration decisions among Canadian organizations

AGRIBUSINESS : AN INTERNATIONAL JOURNAL, Issue 4 2003
Emmanuel K. Yiridoe
This study characterized the costs and benefits associated with adopting ISO 14001 environmental management system (EMS) standard, based on a survey of ISO 14001-registered organizations in Canada. Decision makers are contemplating whether it is necessary to register to one or more of the ISO and other international standards and, if so, which ones. Furthermore, an organization that has registered separate departments to different standards and contemplates integrating such standards across the different units may be interested in attributes of particular units that will facilitate integration. Discriminant analysis was conducted to characterize the factors that distinguish between organizations that adopted ISO 14001 alone (single standard), versus those that registered to ISO 14001 along with other quality, health, and safety standards (i.e., multiple standards). The most important factor that motivated adoption to ISO 14001 was to establish a positive environmental profile, thereby promoting goodwill and integrity. Internal factors tended to dominate the motivations for adopting ISO 14001, supporting the hypothesis that external benefits may not be fully realized due to market and policy failure. Internal costs associated with registration depended on the size of the organization and ranged, on average, from CND$17,000 (for organizations with less than 100 employees), to CND$42,000 (for organizations with more than 500 employees). External costs depended more on the type (i.e., sector of the Canadian economy) than on size of the organization. The most important variable that distinguished between Canadian organizations that adopted ISO 14001 alone versus those that adopted ISO 14001 and other standards was whether the organization had an international orientation, that is, those with more than 50% of services or exports to other countries. [EconLit citations: L150, L200, Q290]. © 2003 Wiley Periodicals, Inc. Agribusiness 19: 439,457, 2003. [source]