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Selected AbstractsBoundary element analysis of driven cavity flow for low and moderate Reynolds numbersINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS, Issue 1 2001M. Aydin Abstract A boundary element method for steady two-dimensional low-to-moderate-Reynolds number flows of incompressible fluids, using primitive variables, is presented. The velocity gradients in the Navier,Stokes equations are evaluated using the alternatives of upwind and central finite difference approximations, and derivatives of finite element shape functions. A direct iterative scheme is used to cope with the non-linear character of the integral equations. In order to achieve convergence, an underrelaxation technique is employed at relatively high Reynolds numbers. Driven cavity flow in a square domain is considered to validate the proposed method by comparison with other published data. Copyright © 2001 John Wiley & Sons, Ltd. [source] Method of moments modelling of cylindrical microwave integrated circuits interconnectionsINTERNATIONAL JOURNAL OF NUMERICAL MODELLING: ELECTRONIC NETWORKS, DEVICES AND FIELDS, Issue 2 2004M. S. Al Salameh Abstract In this paper, a numerical technique suitable for characterizing a wide variety of interconnection configurations printed on cylindrical surfaces, is presented. The interconnection lines may have either finite or infinitesimal cross-sections. To model cylindrical interfaces, suitable space-domain integral equations are formulated to represent the potential on conductors and electric field at dielectric interfaces. The solution of the integral equations is then obtained numerically by applying the method of moments (MOM). The objective of this approach is to determine the capacitance matrix of cylindrical interconnection systems with different configurations. From the capacitance matrix, other quantities such as characteristic impedance, coupling coefficient and effective permittivity can be determined. The numerical technique described in this paper is implemented as a general computer program. Various circular cylindrical as well as elliptical cylindrical structures have been solved including microstrip lines and coplanar waveguide lines. The results obtained compare very well with other published data. Copyright © 2004 John Wiley & Sons, Ltd. [source] Circulating Toll-like receptor (TLR) 2, TLR4, and regulatory T cells in patients with chronic hepatitis CAPMIS, Issue 4 2010JIU-PING WANG Wang J-P, Zhang Y, Wei X, Li J, Nan X-P, Yu H-T, Li Y, Wang P-Z, Bai X-F. Circulating Toll-like receptor (TLR) 2, TLR4, and regulatory T cells in patients with chronic hepatitis C. APMIS 2010; 118: 261,70. The mechanism of hepatitis C virus (HCV) involvement in innate immune responses and immune modulation has not been well characterized. In the present work, we studied Toll-like receptor (TLR) 2 and TLR4, which were recently recognized as the important components of innate immunity, as well as CD4+ CD25+ CD127low/, regulatory T cells (Tregs), which actively suppress pathological and physiological immune response during HCV infection. The study involved 31 chronic hepatitis C patients and 20 healthy controls. TLR2 and TLR4 expression in peripheral blood monocytes and the number of Tregs were examined by flow cytometric analysis. Overexpression of TLR2 and TLR4 was found in chronic hepatitis C patients as compared with controls. Furthermore, increased cytokine production, including that of ,-interferon, tumor necrosis factor-,, interleukin (IL)-6, and IL-8, was observed in peripheral blood mononuclear cells from chronic hepatitis C patients after challenge with TLR2 and TLR4 agonists. The number of Tregs was significantly higher in chronic hepatitis C patients and the increased Tregs were associated with HCV genotype 1b. In vitro studies demonstrated that circulating Tregs suppress T-cell responses in chronic hepatitis C patients. Significant correlations were found between the viral load and Treg number and between TLR2 and TLR4 level in chronic hepatitis C patients. Taken together with other published data, these results suggest that TLR2, TLR4, and Tregs correlate closely with chronic HCV infection. [source] Holocene vegetation and climate changes in Hoton-Nur basin, northwest MongoliaBOREAS, Issue 2 2000PAVEL TARASOV Radiocarbon-dated pollen and diatom records from Hoton-Nur lake (48°40'N, 88°18'E), northwest Mongolia are used to reconstruct Holocene vegetation and climate changes. Steppe, which covered the area some time before 9000 BP (all ages are given in 14C BP), was replaced by boreal conifer forest-steppe by 9000,8500 BP. At the same time, planktonic diatoms increased in abundance from 5 to 45%. After 4000 BP there was a sharp reduction in forest and re-establishment of steppe. Changes in the pollen composition were accompanied by a decrease in the abundance of planktonic diatoms from 35,50% (between 9000 and 5500 BP) to less than 10% soon after 4000 BP. These and other published data from Mongolia suggest wetter conditions during the early and middle Holocene than those of today. This pattern probably reflects an expansion of the Pacific monsoon recorded in geological data from China and simulated in climate-model experiments, and suggests that the summer monsoon influenced a larger area than might appear if the Chinese records only are taken into consideration. [source] Prevalence of foot diseases in outpatients attending the Institute of Dermatology, Bangkok, ThailandCLINICAL & EXPERIMENTAL DERMATOLOGY, Issue 1 2004R. Ungpakorn Summary Two thousand patients who visited the outpatient department at the Institute of Dermatology, Bangkok, were assessed for the presence of foot diseases by questionnaire and physical examination. Abnormalities were detected in 741 individuals (37.1%). Nonfungal conditions were more prevalent (31.4%), mainly consisting of eczema (254 cases, 12.7%) and psoriasis (176 cases, 8.8%). Fungal disease was observed in 119 cases (6.0%). There were 76 cases (3.8%) with tinea pedis and 33 cases (1.7%) with onychomycosis. The identified organisms causing tinea pedis were 57.9% nondermatophyte moulds, 36.8% dermatophytes, and 2.6%Candida spp. The corresponding organisms causing onychomycosis were 51.6% nondermatophyte moulds, 36.3% dermatophytes, and 6.0%Candida spp. Among nondermatophytes, Scytalidium dimidiatum was the leading pathogen while Trichophyton rubrum and T. mentagrophytes were the predominant dermatophytes identified. Diabetes mellitus, peripheral vascular disease and activities related to foot trauma were noted to be predisposing factors for onychomycosis. Footwear, particularly sandals and cut shoes, was the only factor relevant to individuals with tinea pedis (P , 0.05). In contrast with other published data on fungal foot infections, this study disclosed a higher prevalence of nondermatophyte organisms, predominantly S. dimidiatum, as the major cause of tinea pedis and onychomycosis. An increase in awareness is necessary to identify such cases, prevent misdiagnosis and initiate appropriate treatment. [source] |