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Selected AbstractsIdentifying patterns of diversity of the actinopterygian fulcraACTA ZOOLOGICA, Issue 2009Gloria Arratia Abstract Fin rays, scutes or ridge scales, and fulcra have been traditionally interpreted as modified scales, but their diversity has been almost ignored. Based on results presented here, revised definitions of these elements are provided. At least two patterns of basal fulcra are found in actinopterygians: in Pattern I all or most basal fulcra are paired elements, whereas in Pattern II, a series of unpaired basal fulcra that are bifurcated proximally, and whose forking gradually becomes larger caudad, are followed by a series of paired elements. Basal fulcra are commonly present on unpaired fins of lower actinopterygians, including basal neopterygians. Among living fish they are absent in polypteriforms, Amia and teleosts. Fringing fulcra are always paired. Three patterns of fringing fulcra series are described: the series of fringing fulcra in basal actinopterygians is formed by expanded terminal segments of marginal lepidotrichia (Pattern A). Another series is formed by a combination of slightly expanded or modified terminal segments of rays and independent spiny, small elements (Pattern B). The third series is formed of small, spiny ossified elements positioned along the leading marginal fin ray(s) (Pattern C). Other patterns of basal and fringing fulcra remain to be investigated, along with their phylogenetic implications. [source] The isochronic band hypothesis and climbing fibre regulation of motricity: an experimental studyEUROPEAN JOURNAL OF NEUROSCIENCE, Issue 2 2001Masaji Fukuda Abstract The dynamic organization of the olivocerebellar afferent input to Purkinje cells was examined in rat cerebellar cortex. The distribution of synchronous Purkinje cell complex spike activity was characterized, bilaterally, utilizing multiple electrode recordings in crus IIa folium under ketamine anaesthesia. The results confirmed the existence of rostrocaudal complex spike isochronicity bands with a mediolateral width of 500 µm. For a given band, no finer spatial submicrostructures could be discerned at a first-order approximation (two-dimensional projection). Closer analysis determined that isochronicity between bands is not continuous in space but demonstrates discrete discontinuities at the mediolateral boundaries. Principal component multivariate analysis revealed that the first principal component of the spatio-temporal variance is synchronicity along the rostrocaudal band with a decreased level of coupling in the mediolateral direction at the band boundary. Furthermore, this discrete banding isochronicity is organized by the distribution of feedback inhibition from the cerebellar nuclei on to the inferior olive nucleus. The usual multiple band structure can be dynamically altered to a single wide-band dynamic architecture, or to other patterns of activity, as may be required by movement coordination. [source] PERSPECTIVE: SEX, RECOMBINATION, AND THE EFFICACY OF SELECTION,WAS WEISMANN RIGHT?EVOLUTION, Issue 2 2000Austin Burt Abstract., The idea that sex functions to provide variation for natural selection to act upon was first advocated by August Weismann and it has dominated much discussion on the evolution of sex and recombination since then. The goal of this paper is to further extend this hypothesis and to assess its place in a larger body of theory on the evolution of sex and recombination. A simple generic model is developed to show how fitness variation and covariation interact with selection for recombination and illustrate some important implications of the hypothesis: (1) the advantage of sex and recombination can accrue both to reproductively isolated populations and to modifiers segregating within populations, but the former will be much larger than the latter; (2) forces of degradation that are correlated across loci within an individual can reduce or reverse selection for increased recombination; and (3) crossing-over (which can occur at different places in different meioses) will create more variability than having multiple chromosomes and so will have more influence on the efficacy of selection. Several long-term selection experiments support Weismann's hypothesis, including those showing a greater response to selection in populations with higher rates of recombination and higher rates of recombination evolving as a correlated response to selection for some other character. Weismann's hypothesis is also consistent with the sporadic distribution of obligate asexuality, which indicates that clones have a higher rate of extinction than sexuals. Weismann's hypothesis is then discussed in light of other patterns in the distribution of sexuality versus asexuality. To account for variation in the frequency of obligate asexuality in different taxa, a simple model is developed in which this frequency is a function of three parameters: the rate of clonal origin, the initial fitness of clones when they arise, and the rate at which that fitness declines over time. Variation in all three parameters is likely to be important in explaining the distribution of obligate asexuality. Facultative asexuality also exists, and for this to be stable it seems there must be ecological differences between the sexual and asexual propagules as well as genetic differences. Finally, the timing of sex in cyclical parthenogens is most likely set to minimize the opportunity costs of sex. None of these patterns contradict Weismann's hypothesis, but they do show that many additional principles unrelated to the function of sex are required to fully explain its distribution. Weismann's hypothesis is also consistent with what we know about the mechanics and molecular genetics of recombination, in particular the tendency for chromatids to recombine with a homolog rather than a sister chromatid at meiosis, which is opposite to what they do during mitosis. However, molecular genetic studies have shown that cis -acting sites at which recombination is initiated are lost by gene conversion as a result, a factor that can be expected to affect many fine details in the evolution of recombination. In summary, although Weismann's hypothesis must be considered the leading candidate for the function of sex and recombination, nevertheless, many additional principles are needed to fully account for their evolution. [source] Uncertainties in interpretation of isotope signals for estimation of fine root longevity: theoretical considerationsGLOBAL CHANGE BIOLOGY, Issue 7 2003YIQI LUOArticle first published online: 25 JUN 200 Abstract This paper examines uncertainties in the interpretation of isotope signals when estimating fine root longevity, particularly in forests. The isotope signals are depleted ,13C values from elevated CO2 experiments and enriched ,14C values from bomb 14C in atmospheric CO2. For the CO2 experiments, I explored the effects of six root mortality patterns (on,off, proportional, constant, normal, left skew, and right skew distributions), five levels of nonstructural carbohydrate (NSC) reserves, and increased root growth on root ,13C values after CO2 fumigation. My analysis indicates that fitting a linear equation to ,13C data provides unbiased estimates of longevity only if root mortality follows an on,off model, without dilution of isotope signals by pretreatment NSC reserves, and under a steady state between growth and death. If root mortality follows the other patterns, the linear extrapolation considerably overestimates root longevity. In contrast, fitting an exponential equation to ,13C data underestimates longevity with all the mortality patterns except the proportional one. With either linear or exponential extrapolation, dilution of isotope signals by pretreatment NSC reserves could result in overestimation of root longevity by several-fold. Root longevity is underestimated if elevated CO2 stimulates fine root growth. For the bomb 14C approach, I examined the effects of four mortality patterns (on,off, proportional, constant, and normal distribution) on root ,14C values. For a given ,14C value, the proportional pattern usually provides a shorter estimate of root longevity than the other patterns. Overall, we have to improve our understanding of root growth and mortality patterns and to measure NSC reserves in order to reduce uncertainties in estimated fine root longevity from isotope data. [source] Poorly differentiated tumours of the anal canal: a diagnostic strategy for the surgical pathologistHISTOPATHOLOGY, Issue 1 2007B Balachandra Poorly differentiated malignancies affecting the anal canal are uncommon but pose diagnostic difficulties because of the wide range of normal cell types that may occur within a limited anatomical region. The range of lesions that may present as poorly differentiated tumours includes squamous cell carcinoma, adenocarcinoma, small and large cell neuroendocrine carcinoma, neuroendocrine carcinoma expressing epithelial cytokeratins and other patterns of mixed differentiation, undifferentiated carcinoma, malignant melanoma, lymphoma and secondary tumours. This review discusses the differential diagnosis of these neoplasms with the aid of short illustrative case studies. [source] Nanoscale Writing of Transparent Conducting Oxide Features with a Focused Ion BeamADVANCED MATERIALS, Issue 6 2009Norma E. Sosa Embedded, optically transparent, electrically conducting oxide nanowires, and other patterns are written on highly resistive transparent metal oxide thin films with nanoscale spatial control using focused ion beam implantation. The resulting transparent conducting oxide features are 110-160 nm wide, 7 nm deep, and are theoretically limitless in length, connectivity, and shape. [source] Natural regeneration and population dynamics of the tree Afzelia quanzensis in woodlands in Southern AfricaAFRICAN JOURNAL OF ECOLOGY, Issue 4 2009Karin Gerhardt Abstract The logging of tree species of high commercial value is increasing throughout the African continent, yet the ecology of these species is generally poorly known. We studied the regeneration pattern and size class distribution of Afzelia quanzensis populations in northern South Africa over a 5-year period. Recruitment was low as the annual seedling mortality was >65%. Seedlings were located under the canopy and were affected by drought and browsing. The adults were scattered or were in a clump-dispersed pattern, which would result in higher recruitment of offspring near parents. Individuals of 0,10 cm diameter at breast height (DBH) were few, while there were 32 trees ha,1 at >10 cm DBH with an annual mortality of 0.8%. Annual diameter increments varied between 0.06 and 0.28 cm. It appears that the transition from the sapling into the juvenile stage could be a bottleneck in the regeneration of the species. A longer study, including more rainfall cycles, may reveal other patterns as dry and wet years have different impacts on dynamics. Résumé La coupe d'espèces d'arbres de grande valeur commerciale augmente dans tout le continent africain, pourtant l'écologie de ces espèces est généralement mal connue. Nous avons étudié le schéma de régénération et la distribution des classes d'âge des populations d'Afzelia quanzensis dans le nord de l'Afrique du Sud pendant cinq ans. Le recrutement était faible car la mortalité annuelle des jeunes plants était de plus de 65%. Les jeunes plans se trouvaient sous la canopée et étaient affectés par la sécheresse et par le broutage des animaux. Les adultes étaient dispersés ou se trouvaient en un schéma en bosquet, qui résulte en un plus fort recrutement de la progéniture près des parents. Les individus de 0,10 cm DBH étaient rares, alors qu'il y avait32 arbres ha,1à >10 cm DBH, avec une mortalité annuelle de 0,8%. L'incrément annuel du diamètre variait entre 0,06 et 0,28 cm. Il semble que la transition entre le stade de jeune arbre et celui de juvénile pourrait bien constituer un étranglement dans la régénération de l'espèce. Une étude plus longue, comprenant plus de cycles de pluies, pourrait révéler un autre schéma étant donné que les années sèches et humides ont des impacts différents sur cette dynamique. [source] Intrapopulational polymorphism of nucleolus organizer regions in Serrapinnus notomelas (Characidae, Cheirodontinae) from the Paraná RiverJOURNAL OF FISH BIOLOGY, Issue 5 2008A. P. Santi-Rampazzo Analysis of the nucleolus organizer regions by silver nitrate (AgNOR), fluorescent in situ hybridization (FISH) and C-banding of Serrapinnus notomelas from the Paraná River, PR, Brazil revealed intrapopulational polymorphisms that could be classified into six patterns (I,VI). Pattern I consisted of a single nucleolus organizer region (NOR) on chromosome pair 26 with at least one active homologue, indicating that it was a preferential NO. This NOR was also present in all the other patterns. In addition, seven other variable pairs appeared in patterns II,VI. These polymorphisms may indicate transpositions of rDNA genes, located on pair 26, to various sites in the genome. These transpositions may be due to transpose mechanisms or reinsertion into sites that have sequences homologous with the inserts. C-band analysis also reflected this variability and confirmed the various patterns described here. [source] Sexual Dysfunction in an Internet Sample of U.S. Men Who Have Sex with MenTHE JOURNAL OF SEXUAL MEDICINE, Issue 9 2010Sabina Hirshfield PhD ABSTRACT Introduction., Relatively little is known about sexual dysfunction (SD) in men who have sex with men (MSM). Aim., In order to better understand SD symptoms in MSM, we assessed self-reported SD symptoms, individually and by latent class analysis (LCA). Methods., In 2004,2005 an Internet sample of U.S. MSM was recruited from gay-oriented sexual networking, chat and news websites. The analytic sample comprised 7,001 men aged 18 or older who reported lifetime male sex partners and oral or anal sex with a male partner in their most recent encounter within the past year. Main Outcome Measures., Seven questions on SD symptoms that occurred during the past 12 months inquired about low sexual desire, erection problems, inability to achieve an orgasm, performance anxiety, premature ejaculation, pain during sex, and sex not being pleasurable. Results., Self-reported symptoms of SD were high. Overall, 79% of men reported one or more SD symptoms in the past year, with low sexual desire, erection problems, and performance anxiety being the most prevalent. Four distinct underlying patterns of sexual functioning were identified by LCA: no/low SD, erection problems/performance anxiety, low desire/pleasure, and high SD/sexual pain. High SD/sexual pain was distinguished from the other patterns by club drug use and use of prescription and non-prescription erectile dysfunction medication before sex in the past year. Additionally, men associated with the high SD/sexual pain group were younger, single, more likely to have poor mental and physical health, and more likely to have been diagnosed with a sexually transmitted infection in the past year compared to men in the no/low SD group. Conclusions., LCA enabled us to identify underlying patterns of sexual functioning among this sample of MSM recruited online. Future research should investigate these distinct subgroups with SD symptoms in order to develop tailored treatments and counseling for SD. Hirshfield S, Chiasson MA, Wagmiller RL, Remien RH, Humberstone M, Scheinmann R, and Grov C. Sexual dysfunction in an internet sample of U.S. men who have sex with men. J Sex Med 2010;7:3104,3114. [source] Automatic detection of circular structures in high-resolution satellite images of agricultural landARCHAEOLOGICAL PROSPECTION, Issue 1 2009Øivind Due Trier Abstract Archaeological sites are sometimes visible in satellite images as soil or crop marks. At best, the marks are distinct, but they tend to have less contrast with the background than many other patterns in the images. Consequently, reliable automated detection based on pattern recognition is very difficult. Our method detects circle-shaped soil and crop marks in the panchromatic band of high-resolution satellite images of agricultural fields. Such circular marks may be caused by burial mounds. In our approach, local contrast enhancement is applied in order to make weak marks more distinct. The image is then convolved with ring templates of varying sizes, giving high absolute values at candidate circular mark locations. Each candidate mark is presented to an operator, who may reject it. We tested our method on Quickbird images from southeast Norway. The number of detected candidate marks could be varied by changing a threshold value. A reasonable compromise between not detecting too many false rings and at the same time detecting as many true rings as possible, might be when the number of false detections is approximately seven times the number of true detections. In this case, 11 out of 15, or 73%, of the strong rings were detected, and 5 out of 10, or 50%, of the fairly strong rings were detected. This is 16 out of 25 of the strong and fairly strong rings, or 64%. Archaeologists state that the software tool we developed will be helpful for locating potential cultural heritage sites. Although it makes many false detections, it will relieve the operators from time-consuming manual inspection of entire images. Copyright © 2008 John Wiley & Sons, Ltd. [source] Paras, Palaces, Pathogens: frameworks for the growth of Calcutta, 1800,1850CITY & SOCIETY, Issue 1 2000John Archer THE HISTORICAL FABRIC OF CALCUTTA incorporates both the perspective of indigenous knowledges and practices, as well as successive regimes of "improvements" that British colonial authorities sought to introduce in the period 1798-1850. In the face of these diverse interests the urban fabric served as a crurial medium for the negotiation of difference. Portions of the indigenous population selectively adapted their budding designs and social practices to British conventions, while protecting other patterns and practices in efforts both to accommodate and to maintain difference. [Colonial cities, urban planning, hygiene, India, Calcutta] [source] Optimizing the cut in Mohs' micrographic surgery in regard to skin sparing and microscopic view: is a round incision cut necessary?CLINICAL & EXPERIMENTAL DERMATOLOGY, Issue 2 2005T. R. Tilleman Summary Saucer incision is the common cut in Mohs' micrographic surgery. To date no proof as to the superiority of this cut over other patterns has been presented. In this work we examine the round pattern aspect of the saucer incision and answer two questions: does the round cut provide the best skin-sparing pattern? And, does it provide the best microscopic view? A two-dimensional geometric analysis is used to determine whether a round incision is optimal from the standpoint of skin sparing and microscopic view. Mohs' micrographic surgery views are used to back up the geometric hypothesis. The result is that the round incision pattern is skin-wasteful compared to an incision that follows the cancerous lesion. In the lesion presented here the two cuts have a ratio of 1.5 between the two excised skin areas, indicating a waste of healthy skin of 50%. It is also shown that specimens with a pointed edge provide better layer projection. The conclusion is that a tailored cut following the lesion pattern is the optimal Mohs' incision. Therefore in the first stage of Mohs' micrographic surgery the skin cut should replicate the lesion pattern instead of a round saucer cut. Though many Mohs' surgeons already implement this philosophy, in the literature the saucer incision recommended by Dr Frederic Mohs' remains the norm. [source] Measurements of Tooth Movements in Relation to Single-Implant Restorations during 16 Years: A Case ReportCLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, Issue 4 2005Torsten Jemt LSD ABSTRACT Background: Osseointegrated implants behave as ankylotic abutments, and their positions are not affected by dentofacial changes. Purpose: To measure changes in occlusion in relation to single implants in one patient after more than 15 years in function. Materials and Methods: One 25-year-old female was treated with two single implants in the upper central incisor and bicuspid area after trauma. Study casts made prior to treatment (1987) and after 16 years in function (2004) were scanned by means of an optical scanner. Using the palate as the reference, the models were placed in the same coordinate system and analyzed and compared in a computer-aided design (CAD) program. The results of the measurements of the casts were also compared with clinical photographs taken at the time of treatment (1988), after 9 years (1997), and after 16 years (2004) in function. Results: The clinical photographs showed obvious signs of implant infraposition after 9 years. New crowns were made in the incisor region after 15 years (2002), but signs of infraposition were again present at the final examination (2004). Measurements of the casts indicated small tooth movements with a pattern of slight eruption of upper teeth combined with a palatal inclination, mesial drift, and lingual inclination and crowding of the lower anterior teeth. The small measured vertical eruption of the teeth was less than the observed clinical infraposition of the implant crowns, indicating that the vertical position of the palatal may have changed in relation to the implants as well. Conclusion: Obvious dentofacial changes may take place in adult patients. Teeth may adjust for this, and no major problems may arise in the dentate patient. However, because the positions of implants are not affected by dentofacial changes, other patterns of clinical problems can be seen when implant patients present with these changes. The character and frequency of these dentofacial changes that may compromise implant treatment in the long term are not yet known. [source] |