Optical Coherence Tomography Study (optical + coherence_tomography_study)

Distribution by Scientific Domains


Selected Abstracts


Macular appearance after diabetic vitrectomy for fibrovascular proliferation: an optical coherence tomography study

ACTA OPHTHALMOLOGICA, Issue 2 2010
Chung-May Yang
Abstract. Purpose:, To investigate morphological variations in the macular area with optical coherence tomography (OCT) after vitrectomy for diabetic fibrovascular proliferation. Methods:, We reviewed 108 cases using OCT 7,15 months after vitrectomy. Of these, 32 received OCT within 3 months postoperatively. Morphological variations were categorized and correlated with visual outcome. Results:, Only 24 cases (21.4%) had no obvious abnormalities. The most frequent findings were epiretinal membrane (52.8%), macular thickening (37.0%) and macular cysts (28.7%). Multivariate regression showed that diffuse macular thickening, loss of foveal depression and diffuse retinal thinning were significantly associated with poor visual acuity. Sequential OCT (< 3 and , 7 months) revealed that epiretinal membrane and oedema outside of fovea changed significantly between two examinations. Conclusion:, OCT may identify diverse morphological changes in the macular area after diabetic vitrectomy for fibrovascular proliferation. Macular appearance may change over time, and certain types of morphological changes may be associated with poor visual function. [source]


Stratus optical coherence tomography study of filtering blebs after primary trabeculectomy with a fornix-based conjunctival flap

ACTA OPHTHALMOLOGICA, Issue 1 2010
Kazuyuki Hirooka
Abstract. Purpose:, To investigate the relationship between filtering bleb function and Stratus optical coherence tomography (OCT) images. Methods:, We studied 72 eyes of 65 consecutive patients who had a fornix-based conjunctival flap in primary trabeculectomy with mitomycin C (MMC). Filtering blebs with various types of glaucoma were examined using Stratus OCT. Success rates were defined as intraocular pressure (IOP) , 15 mmHg and IOP reduction , 25% without medication or additional surgery. Success rates among classified groups were compared using Kaplan,Meier survival curves and the log-rank test. Results:, Blebs were classified into three different categories on the basis of the following Stratus OCT patterns: cystoid type (multiple cysts inside the bleb; 17 eyes), diffuse type (low to high reflective areas that were mixed inside the bleb; 31 eyes) and layer type (medium to high reflective layer inside the bleb; 24 eyes). Success rates in the cystoid-, diffuse- and layer-type blebs were 94%, 97% and 75% (P = 0.02), respectively. Conclusion:, In trabeculectomy with MMC and a fornix-based conjunctival flap, there is a significant association between the success rates and the postoperative Stratus OCT findings of filtering blebs. [source]


Early changes in clear cornea incision after phacoemulsification: an anterior segment optical coherence tomography study

ACTA OPHTHALMOLOGICA, Issue 7 2009
Yuanling Xia
Abstract. Purpose:, We aimed to investigate the ultrastructures of clear corneal incisions 24 hours after phacoemulsification using anterior segment optical coherence tomography (AS-OCT). Methods:, Sixty eyes of 60 patients scheduled for cataract surgery were randomly selected. All eyes underwent the same phacoemulsification procedure carried out by one experienced surgeon. Two-plane temporal clear corneal tunnel incisions were performed. The same types of intraocular lens and implant system were used in all patients. Images of the ultrastructures of the corneal incisions were taken using AS-OCT before and 1 day after surgery. Results:, Corneal thickness increased at the incision site after surgery in all eyes (p < 0.001). Epithelial bulla in the incision region was seen in two eyes (3%). Gaping at the internal aspect of the corneal wound was seen in 42 eyes (70%). Eyes with gaping had thicker localized cornea (p = 0.002). Descemet's membrane detachment was seen in 49 eyes (82%); this seemed to be associated with lower preoperative intraocular pressure (p = 0.01). Conclusions:, Anterior segment OCT provides sensitive and detailed measurements of the ultrastructures in clear corneal incision. [source]


Retinal nerve fibre layer of perimetrically unaffected eyes of glaucoma patients: an optical coherence tomography study

CLINICAL & EXPERIMENTAL OPHTHALMOLOGY, Issue 2 2009
Stefano Da Pozzo MD PhD
Abstract Purpose:, The aim of this study is to evaluate whether optical coherence tomography (StratusOCT) may detect early changes in perimetrically unaffected (PU) fellow eyes of glaucomatous patients by assessing retinal nerve fibre layer (RNFL) thickness parameters. Methods:, Thirty-seven glaucomatous patients with unilateral field loss and 34 age-matched controls were recruited. In glaucoma patients, PU and perimetrically affected fellow eyes were analysed separately. For each group, mean values (ąSD) of RNFL thickness parameters were calculated and comparisons between fellow eyes of glaucoma patients and between healthy and PU eyes of glaucoma patients conducted with paired t -test and Mann,Whitney U -test, respectively. Proportion of clock-hour sectors flagged with probability <5% or <1% was collected and differences between healthy and PU eyes were evaluated on Fisher exact test. Results:, Global (Average Thickness) and sectoral parameters (Inferior and Nasal Average), Maximum thickness,minimum thickness (Max-min), as well as 2-o'clock (nasal side) and 6-o'clock sectors resulted significantly thinner in PU eyes than in control group. Proportion of eyes with clock-hour position flagged with probability <5% or <1% was not significantly different between healthy and PU eyes. Conclusion:, Despite a standard automated perimetry within normal limits, the StratusOCT detected both localized and diffuse RNFL thinning in PU eyes of glaucoma patients. These eyes should be considered at risk of developing functional damage over time and consequently require thorough monitoring for detecting any sign of progression. [source]