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One-pot Procedure (one-pot + procedure)
Kinds of One-pot Procedure Selected AbstractsChemInform Abstract: One-Pot Procedure for the Synthesis of Unsymmetrical Diarylalkynes.CHEMINFORM, Issue 39 2010Rene Severin No abstract is available for this article. [source] ChemInform Abstract: A Novel One-Pot Procedure for the Stereoselective Synthesis of ,-Hydroxy Esters from Orthoesters.CHEMINFORM, Issue 6 2010Matthias Breuning Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: A One-Pot Procedure for Trifluoroacetylation of Arylamines Using Trifluoroacetic Acid as a Trifluoroacetylating Reagent.CHEMINFORM, Issue 30 2009Junpei Ohtaka Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Easy Approach to ,,,-Unsaturated ,-Thiolactams via a RCM and Thionation One-Pot Procedure.CHEMINFORM, Issue 15 2009Jacek G. Sosnicki Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Novel, One-Pot Procedure for the Synthesis of 2-Arylethanol Derivatives.CHEMINFORM, Issue 41 2008Torsten Schlaeger Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: A Useful One-Pot Procedure for Obtaining 2-Aryl-5-nitrothiophenes (III), (V) from Bromonitromethane and 3-Aryl-3-chloro-propenals.CHEMINFORM, Issue 21 2008Juan C. Rodriguez-Dominguez Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: A Facile, One-Pot Procedure for Forming Diarylimines from Nitroarenes and Benzaldehydes.CHEMINFORM, Issue 9 2008Andrew L. Korich Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Simple, One-Pot Procedure for the Generation of Homoallylic Alcohols from Barbier-Type Allylation of Gem-Diacetates in the Presence of ,-Cyclodextrin in Water.CHEMINFORM, Issue 45 2007M. Somi Reddy Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] An Easy One-Pot Procedure for the Synthesis of N-Sulfonyl Phosphorous Ylides and Sulfonyl Iminophosphoranes.CHEMINFORM, Issue 36 2007Ahmad Shaabani Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Multicomponent One-Pot Procedure for the Synthesis of Free ,-Chiral Amines from Aldehydes.CHEMINFORM, Issue 19 2006Alexandre Cote Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Highly Stereoselective One-Pot Procedure to Prepare Bis- and Tris-chalcogenide Alkenes via Addition of Disulfides and Diselenides to Terminal Alkynes.CHEMINFORM, Issue 45 2005Angelica Venturini Moro Abstract For Abstract see ChemInform Abstract in Full Text. [source] Rhodium-Catalyzed Asymmetric 1,4-Addition of Alkenylsilanes Generated by Hydrosilylation of Alkynes: A One-Pot Procedure Where a Rhodium/(S)-Binap Complex Catalyzes the Two Successive Reactions.CHEMINFORM, Issue 3 2005Yusuke Otomaru Abstract For Abstract see ChemInform Abstract in Full Text. [source] A Convenient One-Pot Procedure to Afford Bicyclic Molecules by Stereospecific Iron Carbonyl Mediated [6 + 2] Ene-Type Cyclization: A Possible Approach to Gelsemine.CHEMINFORM, Issue 12 2004Anthony J. Pearson Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: A Mild One-Pot Procedure for the Polynitration of Activated Arenes.CHEMINFORM, Issue 2 2001Convenient Preparation of Dinitro-, Trinitrodialkoxybenzenes. Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] One-Pot Synthesis of Fluorinated 1-Benzoyl-3,4-dihydroisoquinolines from [2-(o -Alkynylphenyl)ethyl]amines by a Hydroamination/Oxidation SequenceEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 1 2010René Severin Abstract Fluorinated 1-benzoyl-3,4-dihydroisoquinolines can easily be synthesized by a new one-pot procedure from corresponding fluorinated [2-(o -alkynylphenyl)ethyl]amines in high yields. The one-pot process consists of an initial [Ind2TiMe2]-catalyzed intramolecular alkyne hydroamination and a subsequent Pd-catalyzed oxidation of the benzyl side chain of the resulting hydroamination product. The process tolerates electron-donating and -withdrawing substituents on the benzene ring that is converted into the benzoyl side chain of the products as well as ortho -substitution. [source] Superacid-Catalyzed Dimerization/Cyclization of Isopropenyl-PAHs , Novel Pathways to PAH Dimers, Phenalenes and Their Stable CarbocationsEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 21 2008Cédric Brulé Abstract The isopropenyl derivatives of representative classes of polycyclic aromatic hydrocarbons (PAHs) having four and five fused-ring systems, namely pyrene, chrysene, benzo[c]phenanthrene (BcPh), dibenzo[a,c]anthracene (benzo[f]tetraphene) and perylene, were synthesized by Wittig olefination from the corresponding acetyl-PAHs. Under the influence of triflic acid (TfOH), the isopropenyl derivatives were converted to novel PAH dimers and/or phenalenes in a simple one-pot procedure. A plausible mechanism for this process has been outlined, and the synthetic scope of this chemistry has been explored. Structural features in the PAH dimers were examined by DFT. As representative initial and final carbocation intermediates in the reaction sequence, stable carbocations derived from 3-isopropenylperylene and from 4,6,6-trimethyl-6H -dibenzo[a,kl]anthracene were generated and studied directly by NMR spectroscopy. The NMR characteristics and charge delocalization modes in the resulting benzylic carbocations are discussed. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008) [source] Synthesis of New Sterically Hindered AnilinesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 19 2007Barry R. Steele Abstract Ring-alkylated primary, secondary and tertiary anilines have been ethylated with ethylene at benzylic positions in a simple and inexpensive one-pot procedure which is mediated bythe use of the superbase system nBuLi/LiK(OCH2CH2NMe2)2in the presence of Mg(OCH2CH2OEt)2. Primary and secondary anilines are ethylated readily at ortho -benzylic positions but with difficulty or not at all at other positions. Tertiaryanilines are ethylated at all positions. Mono- or diethylation occurs depending on the steric constraints present.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source] Mild Synthesis of ,-Amino-,,,-difluoro Ketones from Acylsilanes and Trifluoromethyltrimethylsilane in a One-Pot Imino Aldol Reaction,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 20 2005Sylvain Jonet Abstract ,-Amino-,,,-difluoro ketones have been very conveniently prepared in a one-pot procedure from acylsilanes, trifluoromethyltrimethylsilane and imines. The key intermediate in this reaction is a difluoroenoxysilane. The Lewis acid promoted imino aldol reaction was performed with BF3·OEt2 or under very mild conditions using a catalytic amount of Yb(OTf)3. The reaction with chiral benzylimines occurred in good yield with 52,78,% de. Palladium-catalyzed hydrogenolysis furnished an unprotected ,-amino-,,,-difluoro ketone or a ,-amino-,,,-difluoro alcohol. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) [source] Asymmetric Synthesis of ,,,-Substituted ,-Sultones via Allylation of Chiral Lithiated SulfonatesEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 20 2003Dieter Enders Abstract The first auxiliary controlled asymmetric synthesis of enantiopure ,,,-substituted ,-sultones via ,-allylation of lithiated sulfonates by using 1,2:5,6-di- O -isopropylidene-,- D -allofuranose as chiral auxiliary is described. The high asymmetric inductions of the ,-allylations were reached in good to excellent yields. Successive epimerization-free cleavage of the auxiliary and diastereoselective ring closure of the sulfonic acid intermediates in a one-pot procedure led to the title compounds in good to excellent yields and diastereo- and enantiomeric excesses (de, ee , 98%). (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003) [source] One-Pot Synthesis of 5-Substituted 1H -Tetrazoles from Aryl Bromides with Potassium Hexakis(cyano- ,C)ferrate(4,) (K4[Fe(CN)6]) as Cyanide SourceHELVETICA CHIMICA ACTA, Issue 1 2009Yizhong Zhu Abstract A one-pot procedure for the synthesis of 5-substituted 1H -tetrazoles through the three-component reaction between an aryl bromide, potassium hexakis(cyano- ,C)ferrate(4,) (K4[Fe(CN)6]) and NaN3 catalyzed by [Pd(OAc)2] and ZnBr2 in the presence of 1,4-diazabicyclo[2.2.2]octane (dabco) was developed. Furthermore, the reaction occurred under nonacidic conditions and involved a nontoxic cyanide source, making this method a quite attractive one. [source] An efficient one-pot procedure for the preparation of 1,3,4-thiadiazoles in ionic liquid [bmim]BF4 as dual solvent and catalystHETEROATOM CHEMISTRY, Issue 3 2008Shahnaz Rostamizadeh The one-pot three component condensation of hydrazine hydrate with substituted phenylisothiocyanates followed by the addition of substituted benzaldehydes in the presence of ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4) and in the absence of any other catalyst under mild condition afforded 1,3,4-thiadiazoles in excellent yields. The reaction workup is simple, and the ionic liquid was easily recovered from the reaction and reused. © 2008 Wiley Periodicals, Inc. Heteroatom Chem 19:320,324, 2008; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20432 [source] A novel one-pot procedure for preparation of some new condensed pyrido[2,3- d]pyrimidine(1H,3H)-2,4-dionesHETEROATOM CHEMISTRY, Issue 1 2007Javad Azizian A novel one-pot procedure for preparation of some new condensed pyrido[2,3- d]pyrimidine(1H,3H)-2,4-diones based on condensation of ninhydrin, alkyl cyanoacetate, and 6-aminouracil derivatives has been reported. The reactions were carried out in refluxed ethanol and were completed in less than 2 h. © 2007 Wiley Periodicals, Inc. Heteroatom Chem 18:16,18, 2007; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20242 [source] A convenient synthesis of N - t -butyl- N,-aminocarbonyl- N -(substituted)benzoyl-hydrazine containing , -aminoalkylphosphonate groups in a one-pot procedureHETEROATOM CHEMISTRY, Issue 2 2001Qingmin Wang A variety of novel N-t-butyl-N,-aminocarbonyl-N-(substituted)benzoylhydrazines containing ,-aminoalkylphosphonate groups were synthesized. Treatment of ,-aminoalkylphosphonates with triphosgene yielded ,-isocyanatoalkylphosphonates, and subsequent addition with N-t-butyl-N-substituted benzoylhydrazines provided the title compounds in a one-pot procedure with good yields. The triphosgene-mediated reaction for the synthesis of ,-isocyanatoalkylphosphonates enjoys a number of advantages: the reaction is carried out under mild condition in good yield, triphosgene is relatively safe to handle because of its low vapor pressure and high stability, and the experimental procedure is simple. This method can be applicable to the synthesis of other ,-isocyanatoalkyl-phosphonates and urylenediphosphonates. The structures of all of the products and by-products were confirmed by 1H NMR, 31P NMR, IR and mass spectroscopy, and elemental analysis. We also found that some of the compounds possess potential antitobacco mosaic virus (TMV) activities and anticancer activities. © 2001 John Wiley & Sons, Inc. Heteroatom Chem 12:68,72, 2001 [source] Efficient Enantioselective Syntheses of Sertraline, 2-Epicatalponol and Catalponol from Tetralin-1,4-dioneADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 13 2010Alvaro Enriquez Garcia Abstract Tetralin-1,4-dione, the stable tautomer of dihydroxynaphthalene, was reduced with catecholborane in the presence of 3,3-diphenyl-1-butyltetrahydro-3H -pyrrolo[1,2- c][1,3,2]oxazaborole as catalyst to give enantiomerically highly enriched 4-hydroxy-1-tetralone (99% ee) in an efficient one-pot procedure. The R -enantiomer provided a rapid access to sertraline while the S -enantiomer was converted into 2-epicatalponol and catalponol. A more selective enantioselective route to the antithermitic catalponol made use of the planar chiral tricarbonylchromium complex of hydroxytetralone. Its precursor chromium(tricarbonyl)[,6 -(1-4,4a,8a)-tetralin-5,8-dione] was obtained via direct complexation of 1,4-dihydroxynaphthalene using chromium(tricarbonyl)- tris(ammonia) and boron trifluoride etherate as source of the chromium(tricarbonyl) fragment. Enolate prenylation was best carried out in the presence of a tetraamine ligand. Complete inversion of the stereogenic center bearing the prenyl group of the initially obtained tetralone complex was achieved via enolate formation followed by protonation. [source] The First Example of Saccharin-Lithium Bromide Catalysis: Direct Synthesis of N -Tosylimines from AlcoholsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 10 2010Rajesh Patel Abstract The first procedure to access N -tosylimines directly from alcohols under mild and neutral conditions is reported. The protocol involves saccharin-lithium bromide-catalyzed oxidation of alcohols to aldehydes/ketones with chloramine-T followed by their condensation with the in situ generated oxidation by-product p -toluenesulfonamide in the same reaction vessel to afford N -tosylimines in 40,90% overall yields. The present work opens up a new and efficient synthetic route to N -tosyimines directly from alcohols in a one-pot procedure. [source] Pyrazole Synthesis Using a Titanium-Catalyzed Multicomponent Coupling Reaction and Synthesis of WithasomnineADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2009Supriyo Majumder Abstract The titanium-catalyzed 3-component coupling of an alkyne, isonitrile, and amine can be used to generate tautomers of 1,3-diimines. These diimines produced in situ undergo cyclization with hydrazine and hydrazine derivatives in a one-pot procedure to provide pyrazoles. Seventeen examples of pyrazoles are provided using this one-pot, 4-component procedure from simple starting materials. The regioselectivity of the alkyne addition can be controlled in some cases with catalyst architecture, and regioselectivity of monosubsituted hydrazines to unsymmetrical 1,3-diimines is discussed. This multicomponent coupling strategy was applied to the synthesis of withasomnine in an efficient procedure, which gave the natural product in 24% overall yield from 4-pentyn-1-ol. [source] Selective Oxidative Ligand Coupling of Organoborates Bearing an Alkynyl GroupADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 7-8 2009Toru Amaya Abstract Selective oxidative ligand coupling of alkynyl(triaryl)borates was achieved by treatment with ethoxyvanadyl dichloride [VO(OEt)Cl2] to form the spsp2 carbon-carbon bond. A one-pot procedure through the in situ preparation of the borate was demonstrated using triphenylborane and 1-ethynyl-4-methoxybenzene. [source] Copper Nanoparticles on Charcoal for Multicomponent Catalytic Synthesis of 1,2,3-Triazole Derivatives from Benzyl Halides or Alkyl Halides, Terminal Alkynes and Sodium Azide in Water as a "Green" SolventADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 1-2 2009Hashem Sharghi Abstract A one-pot procedure for synthesis of 1,2,3-triazole derivatives via the three-component coupling (TCC) reaction between terminal alkynes, benzyl or alkyl halides, and sodium azide in the presences of 1,mol% nanoparticles copper/carbon (Cu/C) catalyst has been developed. The catalyst showed high catalytic activity and 1,4-regioselectivity for the [3+2],Huisgen cycloaddition in water as a "green" solvent and good to excellent yields were obtained in all cases. This procedure eliminates the need to handle organic azides, and they are generated in situ. The reaction has a broad scope and is especially practical for the synthesis of new azacrown ether and anthraquinone derivatives of triazole. The heterogeneous catalysts were fully characterized by scanning electron microscopy (SEM), atomic forced microscopy (AFM), X-ray diffraction (XRD), inductively coupled plasma (ICP) analysis and FT-IR experimental techniques. The catalyst was recycled ten times without significant loss of activity. [source] A convenient one-pot procedure for the synthesis of 2-aryl quinazolines using active MnO2 as oxidantJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 5 2010Yi-Yuan Peng A variety of 2-aryl quinazolines were synthesized from the condensation of 2-aminobenzylamines and aryl aldehydes to form 2-aryl-1,2,3,4-tetrahydroquinazolines and subsequent oxidation of the intermediates with MnO2. J. Heterocyclic Chem., (2010). [source] One-pot synthesis of new spiro[cyclopropane-1,3,-[3H]indol]-2,(1,H)-ones from 3-phenacylideneoxindolesJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 4 2010Masoud Shaabanzadeh In a one-pot procedure, the 3-phenacylideneoxindoles 1a,d were reacted with hydrazine and then in situ with lead(IV) acetate and new diastereoisomers of spiro[cyclopropane-1,3,-[3H]indol]-2,(1,H)-ones were prepared. Compounds 1a,d underwent a highly diastereoselective cyclopropanation leading to diastereoisomers 2a,d. These new compounds containing both 2-oxindole and cyclopropane moieties may be valuable in medicinal chemistry. J. Heterocyclic Chem., (2010). [source] | |||||||||||||