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Onset Type 1 Diabetes (onset + type_1_diabetes)

Distribution by Scientific Domains
Medical Sciences100%

Kinds of Onset Type 1 Diabetes

  • childhood onset type 1 diabetes
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    Selected Abstracts

    Secular trends, disease maps and ecological analyses of the incidence of childhood onset Type 1 diabetes in Northern Ireland, 1989,2003

    DIABETIC MEDICINE, Issue 3 2007
    C. R. Cardwell
    Abstract Aims To investigate secular trends in the incidence of Type 1 diabetes in Northern Ireland over the period 1989,2003. To highlight geographical variations in the incidence of Type 1 diabetes by producing disease maps and to compare incidence rates by relevant area characteristics. Methods New cases of Type 1 diabetes in children aged 0,14 years in Northern Ireland were prospectively registered from 1989 to 2003. Standardized incidence rates were calculated and secular trends investigated. Bayesian methodology was used to produce maps of disease incidence using small geographical areas (582 electoral wards). Ecological analyses were conducted using Poisson regression to investigate incidence rates by area characteristics at a finer geographical subdivision (5022 census output areas). Results In Northern Ireland during 1989,2003, there were 1433 new cases, giving a directly standardized incidence rate of 24.7 per 100 000 person-years. This incidence rate increased by a mean of 4.2% per annum. Disease maps highlighted higher incidence rates in the predominately rural north-east of the province and lower incidence rates in the urban areas around Belfast in the east and Derry in the north-west of the province. Ecological analysis identified higher incidence in rural areas (P < 0.001), areas with low migration rates (P = 0.002), affluent areas (P < 0.0001), sparsely populated areas (P = 0.0001) and remote areas (P = 0.005). Conclusions In Northern Ireland the incidence of Type 1 diabetes is increasing. The observed higher incidence in rural, affluent, sparsely populated and remote areas may reflect a reduced or delayed exposure to infections in these areas. [source]

    The PAX4 gene variant A1168C is not associated with early onset Type 1 diabetes in a UK population

    DIABETIC MEDICINE, Issue 8 2006
    R. J. L. Martin
    No abstract is available for this article. [source]

    Hypoglycaemia in childhood onset type 1 diabetes,part villain, but not the only one

    PEDIATRIC DIABETES, Issue 2 2010
    Elisabeth A Northam
    Northam EA, Lin A. Hypoglycaemia in childhood onset type 1 diabetes ,part villain, but not the only one. [source]

    Perinatal risk factors for early childhood onset type 1 diabetes in Austria , a population-based study (1989,2005)

    PEDIATRIC DIABETES, Issue 3pt1 2008
    Thomas Waldhoer
    Background:, To investigate the rapid increase in incidence of type 1 diabetes mellitus (T1DM) in children <5 yr in Austria. Methods:, Data of children born between 1989 and 2005 (n = 444) from the T1DM children incidence registry were linked with birth certificates (n = 1 407 829). Results:, Age of mother, level of education, birth weight, birth length, body mass index, and APGAR score at 10 min were not significant. Boys have about 25% higher risk than girls [hazard ratio = 0.75, 95% confidence interval (CI): 0.62,0.91]. The risk of developing diabetes increases over time significantly (1989,1991 vs. 2001,2005, hazard ratio = 2.86, 95% CI: 2.07,3.94). The linear effect of parity is borderline significant (p = 0.045), with lower risks for second and later born siblings. Marital status is significant [hazard ratio = 0.73, 95% CI: 0.57,0.90)]. Native-born children exhibit twice as high risk as non-native children (hazard ratio = 0.51, 95% CI: 0.37,0.71). Birth weight shows a positive but not significant effect on risk of T1DM. Conclusions:, In this very young and rapidly increasing cohort of diabetic children <5 yr of age, no association with birth weight but with year of birth, gestational age, nationality and parity could be observed. [source]