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Selected AbstractsInvestigating Sexual Abuse: Findings of a 15-Year Longitudinal StudyJOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES, Issue 3 2005Bob McCormack Background, There is a lack of longitudinal large-scale studies of sexual abuse in intellectual disability services. Such studies offer opportunities to examine patterns in disclosure, investigation and outcomes, and to report on incidence and trends. Methods, All allegations of sexual abuse (n = 250) involving service users as victims or perpetrators of sexual abuse over a 15-year period in a large Irish community-based service were analysed based on the data extracted from extensive contemporaneous case notes. Results, Victims or families were the most common concern raisers of abuse. Following multidisciplinary investigation, almost half (47%) of all allegations of sexual abuse were confirmed (n = 118). In confirmed episodes, more than half the perpetrators were adolescents and adults with intellectual disabilities, while almost a quarter were relatives. The most common type of abuse was sexual touch, although 31% of episodes involved penetration or attempted penetration. The most common location was the family home, followed by the day service and public places. A notable feature was the variation in the incidence of abuse over the study period, largely caused by episodes of multiple abuse. Conclusions, The incidence of confirmed episodes of sexual abuse of adults with intellectual disabilities may be higher than previously estimated. There is an urgent need for statutory guidelines, which require reporting of adult abuse, and provide protection for bona fide whistle blowers, similar to existing child protection legislation. [source] Technology Advances and Tanker Spill PreventionNAVAL ENGINEERS JOURNAL, Issue 4 2001Cdr. G. Rodgers USCGR (Ret.) ABSTRACT Goals to alert the bridge watch for imminent grounding or collision with shallow underwater dangers, have long been stymied by lags in active sonar technology. Thus "lower hemisphere" designs for shallow underwater search have been unable to exploit solutions useful topside for the "upper hemisphere" guarded by radar and other technology. While the radar environment normally exhibits single path, direct line-of-sight conditions for prime targets, the shallow water sonar environment is cluttered by a mix of echoes and multipath returns for identical ranges. Thus we first must accommodate to a quirky hydroacoustic environment as a major design subsystem for any shallow water navigational sonar. Secondly, for large carriers found in the world tanker fleet, there is recognition that some simple backfit solution is needed for any electroacoustic interface, the sonar transducer. Commercial carriers have not been designed or built with special hull considerations such as sonar domes and recesses; therefore, this second vital subsystem requires particular design attention for projecting hydro-acoustic energy and receiving return echoes. Several recent patents are on file which apply to this problem. Thirdly, signal processing considerations provide a set of design-critical factors. High speed digital signal processors (DSPs) of recent "parallel" design offer opportunities to search at high speed and to unravel the confusing mix of acoustic energy found in shallow water returns. Past hurdles are endemic for these three critical subsystems: hydroacoustic environment, electroacoustic transducer design, and signal processing, but now these seem most amenable to technology transfer. [source] Breaking out of the binaryPSYCHOTHERAPY AND POLITICS INTERNATIONAL, Issue 3 2010Jane Dudley Abstract Do transgender people transcend gender or merely cross from one side of a physical binary divide to the other? Can such transcendence offer opportunities for arguments in support of unconscious life which the majority of psychotherapists would fight for, but often without success. Can the transgendered person offer us a way of thinking about what is termed and fixed as a category as mental illness. Copyright © 2010 John Wiley & Sons, Ltd. [source] Movement skills proficiency and physical activity: A case for Engaging and Coaching for Health (EACH),ChildAUSTRALIAN OCCUPATIONAL THERAPY JOURNAL, Issue 4 2009Jenny Ziviani Background/aim:,Supporting children's participation in health-enhancing physical activities is an important occupational goal for therapists. Fundamental movement skills (FMS) are thought to underpin and enable many activity options. This study had two goals: first, to examine the relationship between fundamental movement skills (FMS) and physical activity, and second, to use this and existing evidence to inform strategies whereby children's motivation for and engagement in physical activity can be supported. Methods:,A cross-sectional investigation of 124 children, aged 6,12 years, was undertaken. FMS were assessed using the Movement Assessment Battery for Children (M-ABC) and physical activity by pedometer step counts. Results:,A weak but significant association was found between weekend physical activity and balance skills for girls. Correlations between physical activity and ball skills or manual dexterity were not significant for either gender, however, having age appropriate ball skills did result in greater but not significant levels of physical activity for all children when grouped together. Conclusions:,Findings from this study question the magnitude of the relationship between children's FMS and physical activity as measured by pedometers. If the goal of health enhancement through physical activity engagement is to be realised, it is proposed that community, occupation-based approaches may offer more potential than skills-based interventions at increasing activity participation. The concept of Engaging and Coaching for Health (EACH)-Child is introduced to this end. Occupational therapists are encouraged to work collaboratively with school and community organisations to assist children to find the physical activities that best accommodate their interests, abilities and offer opportunities for lifelong engagement. [source] A dating intercomparison study on Late Stone Age coastal midden deposits, South AfricaGEOARCHAEOLOGY: AN INTERNATIONAL JOURNAL, Issue 6 2008Mark D. Bateman The southern and western coastlines of South Africa have an extensive archaeological record with many sites associated with widespread eolian deposits. While much of this rich archaeological record is based on cave sites, evidence of Late Stone Age occupation is additionally preserved in the form of open-site shell middens. We present here a comparative study of the application of amino acid racemization (AAR), optically stimulated luminescence (OSL), and radiocarbon analyses to three Late Stone Age (LSA) midden sites found within dunes on the southern coastline of South Africa. Preliminary geochronological analyses suggest that middens offer opportunity to fill in gaps in what is still a fragmentary archaeological record. Results show OSL and radiocarbon ages in good agreement, illustrating the potential to date not only the middens but also the surrounding dunes that constituted the dwelling sites. AAR results show increasing ratios with age and also that the application of paired shell and "whole rock" AAR can provide insights into the degree of biogenic sediment recycling at buried midden sites. However, the work also highlights that caution is required when OSL sampling sediment associated with middens which may have undergone human disturbance and that further work is required to improve the regional marine reservoir correction for radiocarbon dating in this part of South Africa. The study also illustrates that AAR will only provide useful data provided that middens have been sufficiently deeply buried to overcome fluctuations in environmental variables that affect the racemization rate and that inter-genus comparisons should be avoided. © 2008 Wiley Periodicals, Inc. [source] An environment for prosperity and quality living accommodating growth in the Thames ValleyCORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT, Issue 1 2004Hugh Howes The Thames Valley is seen as the powerhouse of the British economy, and one of the best performing regions in Europe. This economic base offers opportunities for expansion with the potential for it to become the knowledge capital of Europe. Business interests view the area as a highly desirable location, not only because of its markets, skills and proximity to the City and Heathrow but also because of its high quality environment. Companies, however, complain of skills shortages, traffic congestion, lack of suitable premises and housing that is affordable to the workforce. Much of the Thames Valley is either Green Belt or Areas of Outstanding Natural Beauty. Furthermore, the availability of future water supplies, the maintenance of the quality of water in the rivers and managing flood risk are also likely to act as constraints on development in the future. How economic growth is to be achieved with minimal additional development and without detriment to the environment is the central question that is likely to dominate planning in the this region over the next few years. Is it possible to achieve more with existing resources? Copyright © 2004 John Wiley & Sons, Ltd and ERP Environment. [source] Expanding the destination image: wine tourism in the Canary IslandsINTERNATIONAL JOURNAL OF TOURISM RESEARCH, Issue 5 2009Pascal Scherrer Abstract Tourism to the Canary Islands is centred around competitively priced holidays focused on the sun and beach mass tourism experience. A restructure of the islands' wine industry offers opportunities for developing new tourism alternatives based on gourmet products and traditional landscapes. This paper examines the potential of wine tourism from winery operators' perspectives. Challenges to overcome in the development of a successful sustainable local wine tourism industry include the need for expansion of the destination image to reflect the region's wine-making history and scenic qualities; a shift towards independent high-yield travellers; and reintroducing local produce in the mass tourism product. Copyright © 2008 John Wiley & Sons, Ltd. [source] Reflective practice in nursing ethics education: international collaborationJOURNAL OF ADVANCED NURSING, Issue 2 2004Carol J. Leppa PhD RN Background., The Internet provides the opportunity for international comparative study and collaboration when learning about ethics in clinical nursing practice. Aim., This paper aims to discuss Internet links developed between US and UK postregistration nursing students who were reflecting on clinical practice in order to explore how political and organizational structures of the health care system affect ethical decision-making. Discussion., An analysis is presented of the stages in developing an exchange course for students from these countries, which involved various combinations of classroom-based teaching, on-line discussions and international visits by students and teachers during its evolution. The strengths and weaknesses of the different methods are considered, and future developments identified. Conclusion., The Internet collaboration resulted in postregistration nursing students using reflection on practice in the study of ethics in clinical practice and an understanding of how systems structures and procedures affect ethical decision making. Internet-assisted teaching offers opportunities for collaboration, and student participants demonstrate sophisticated critical thinking in ethical decision-making. Issues of access barriers and motivation remain challenges to wider use. [source] Incidence of Dementia, Alzheimer's Disease, and Vascular Dementia in Italy.JOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 1 2002The ILSA Study OBJECTIVES: To estimate the incidence of dementia, Alzheimer's disease (AD), and vascular dementia (VaD) in older Italians and evaluate the relationship of age, gender, and education to developing dementia. DESIGN: Cohort incidence study in the context of the Italian Longitudinal Study on Aging. SETTING: Population sample from eight Italian municipalities. PARTICIPANTS: A dementia-free cohort of 3,208 individuals (aged 65,84), individuated after a baseline evaluation performed in 1992 / 93, aimed at detecting prevalent cases. MEASUREMENTS: The dementia-free cohort was reexamined in 1995 to identify incident cases. The Mini-Mental State Examination (cutoff 23 / 24) was employed to screen for dementia. Trained neurologists evaluated the individuals who screened positive. Final diagnoses had to meet Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised criteria for dementia, National Institute of Neurological and Communicative Disorders and Stroke,Alzheimer's Disease and Related Disorders Association criteria for AD, and International Classification of Diseases, Tenth Revision criteria for VaD. RESULTS: Before the follow-up examination, 382 individuals had died (232 had reliable information). Of the 2,826 survivors, 2,266 completed the study. Overall, 127 new dementia cases were identified. Average incidence rates per 1,000 person-years were 12.47 (95% confidence interval (CI) = 10.23,14.72) for dementia, 6.55 (95% CI = 4.92,8.17) for AD, and 3.30 (95% CI = 2.14,4.45) for VaD. Both AD and VaD showed age-dependent patterns. Education was protective against dementia and AD. Women carried a significantly higher risk of developing AD (hazard ratio = 1.67, 95% CI = 1.02,2.75), and men of developing VaD (hazard ratio = 2.23, 95% CI = 1.06,4.71). CONCLUSIONS: Incidence of dementia in Italy paralleled that in most industrialized countries. About 150,000 new cases per year are expected. A significant gender effect was evidenced for major dementia subtypes. The burden of VaD, especially in men, offers opportunities for prevention. [source] DEFINITION OF INTERNAL MORPHOLOGY AND STRUCTURAL CHANGES DUE TO DEHYDRATION OF RADISH (RAPHANUS SATIVUS L. CV. SUPRELLA) USING MAGNETIC RESONANCE IMAGING SPECTROSCOPYJOURNAL OF FOOD QUALITY, Issue 5-6 2005ANNA SALERNO ABSTRACT Magnetic resonance imaging (MRI) spectroscopy is a promising nondestructive analytical technique in food science. It offers the unique opportunity of studying vegetables, fruits and other foods in general, in their wholeness without any preparative manipulation of the sample. The aim of this study was to investigate the internal structure of radish and to monitor the variations induced by postharvest storage at low relative humidity. The MRI allowed for a clear definition of the internal structure of radishes with distinct visibility of xylematic and phloematic vessels distributed in a radial way. A decrease in water content, which results in the breakdown of tissues and the formation of large cavities with the detachment of the external cortex, is the main consequence of a few days' storage in low relative humidity. Both of these are factors that drastically decrease the quality of the radish's fleshy root. The MRI images give a novel insight into the internal organization of the hypocotyl, and this offers opportunities for further studies with regard to the structural differences related to the cultivars as well as the cultivation system. [source] Synthesis and Bioaccessibility of Fe-Pheophytin Derivatives from Crude Spinach ExtractJOURNAL OF FOOD SCIENCE, Issue 5 2008R.E. Nelson ABSTRACT:, Heme iron is recognized as a highly bioavailable source of iron suitable for treatment of iron deficiency anemia. However, the animal origin of purified heme limits its broad applicability due to religious, personal, and food safety issues. Development of chlorophyll-derived heme mimetics offers opportunities to expand current iron fortification strategies. The objective of this study was the synthesis of Fe-pheophytin (FePhe) derivatives from natural chlorophyll and subsequent evaluation of their digestive behavior and bioaccessibility in vitro. FePhe a and a, were synthesized from crude spinach extracts by treatment with 1.3 M iron(II)chloride and 0.25 M Na-acetate dissolved in glacial acetic acid at 80 °C for 30 min. FePhe-rich extracts (approximately 1 mM) were formulated into corn starch based test meals (7.5% lipid) and subjected to a 2-step in vitro digestion designed to simulate in vivo gastric and small intestinal conditions. Recovery of FePhe following digestion and transfer of FePhe and pheophytins (Phe) from test meal matrix to mixed micelles was assessed by RP C18-HPLC to determine the digestive stability and micellarization efficiency (bioaccessibility). FePhe a and a, derivatives were moderately stable to digestive conditions with recoveries of 52.3% and 58.7%, respectively. Residual Phe a was stable to digestion. Micellarization efficiency of FePhe a (4%) and a, (3.4%) was significantly (P < 0.05) lower than Phe a (25.8%) from test meals. While digestive stability and micellarization efficiency are limiting, the presence of lipophilic FePhe derivatives in mixed micelles suggests that these compounds would be available for subsequent absorption in the intestinal tract. [source] Recommendations for Integrating Restoration Ecology and Conservation Biology in Ponderosa Pine Forests of the Southwestern United StatesRESTORATION ECOLOGY, Issue 1 2006Reed F. Noss Abstract Over the past century, ponderosa pine,dominated landscapes of the southwestern United States have been altered by human activities such as grazing, timber harvest, road building, and fire exclusion. Most forested areas within these landscapes now show increased susceptibility to stand-replacing fires, insect outbreaks, and drought-related mortality. Recent large wildfires in the region have spurred public interest in large-scale fuel reduction and restoration programs, which create perceived and real conflicts with the conservation of biodiversity. Conservation concerns include the potential for larger road networks, soil and understory disturbance, exotic plant invasion, and the removal of large trees in treated areas. Pursuing prescribed burning, thinning, or other treatments on the broad scale that many scientists and managers envision requires the reconciliation of ecological restoration with biodiversity conservation. This study presents recommendations from a workshop for integrating the principles and practices of restoration ecology and conservation biology, toward the objective of restoring the composition, structure, and function of dry ponderosa pine forests. Planning on the scale of hundreds of thousands of hectares offers opportunities to achieve multiple objectives (e.g., rare species protection and restoration of ecological structures and processes) that cannot easily be addressed on a site-by-site basis. However, restoration must be coordinated with conservation planning to achieve mutual objectives and should include strict guidelines for protection of rare, declining, and sensitive habitats and species. [source] Investigation of Lymphocyte Depletion and Repopulation Using Alemtuzumab (Campath-1H) in Cynomolgus MonkeysAMERICAN JOURNAL OF TRANSPLANTATION, Issue 4 2010D. J. Van Der Windt As the target CD52 molecule is expressed on erythrocytes of most nonhuman primate strains, using alemtuzumab in these species would cause massive hemolysis. Six cynomolgus monkeys of Indonesian origin, screened by agglutination assay for absence of CD52 on erythrocytes, were administered alemtuzumab in a cumulative dose to a maximum of 60 mg/kg. In two monkeys, mycophenolate mofetil (MMF) was added as maintenance therapy. Complete depletion of T and B lymphocytes (>99.5%) was achieved with 20 mg/kg alemtuzumab and was more profound than in monkeys treated with antithymocyte globulin (n = 5), as quantified by flow cytometry. Repopulation was suppressed by weekly injections of 10 mg/kg. Without MMF, repopulation of CD20+B cells and CD8+T cells was complete within 2 and 3 months, respectively, and repopulation of CD4+T cells was 67% after 1 year. MMF significantly delayed CD4+T-cell repopulation. Among repopulating CD4+ and CD8+ T cells, a phenotypic shift was observed from CD45RAhiCD62Lhi naïve cells toward CD45RAloCD62Llo effector memory cells. In lymph nodes, the depletion of naïve cells was more profound than of memory cells, which may have initiated a proliferation of memory cells. This model offers opportunities to investigate lymphocyte depletion/repopulation phenomena, as well as the efficacy of alemtuzumab in preclinical transplantation models. [source] Molecular systematics and population genetics of biological invasions: towards a better understanding of invasive species managementANNALS OF APPLIED BIOLOGY, Issue 1 2009J. Le Roux Abstract The study of population genetics of invasive species offers opportunities to investigate rapid evolutionary processes at work, and while the ecology of biological invasions has enjoyed extensive attention in the past, the recentness of molecular techniques makes their application in invasion ecology a fairly new approach. Despite this, molecular biology has already proved powerful in inferring aspects not only relevant to the evolutionary biologist but also to those concerned with invasive species management. Here, we review the different molecular markers routinely used in such studies and their application(s) in addressing different questions in invasion ecology. We then review the current literature on molecular genetic studies aimed at improving management and the understanding of invasive species by resolving of taxonomic issues, elucidating geographical sources of invaders, detecting hybridisation and introgression, tracking dispersal and spread and assessing the importance of genetic diversity in invasion success. Finally, we make some suggestions for future research efforts in molecular ecology of biological invasions. [source] CONGESTIVE CARDIAC FAILURE: URBAN AND RURAL PERSPECTIVES IN VICTORIAAUSTRALIAN JOURNAL OF RURAL HEALTH, Issue 6 2003Mohammad Z. Ansari ABSTRACT Objective:,Effective and timely care for congestive cardiac failure (CCF) should reduce the risks of hospitalisation. The purpose of this study is to describe variations in rates of hospital admissions for CCF in Victoria as an indicator of the adequacy of primary care services. Detailed analyses identify trends in hospitalisations, urban/rural differentials and variations by the Primary Care Partnerships (PCP). Setting:,Acute care hospitals in Victoria. Design:,Routine analyses of age and sex standardised admission rates of CCF in Victoria using the Victorian Admitted Episodes Dataset from 1993,1994 to 2000,2001. Subjects:,All patients admitted to acute care hospitals in Victoria with the principal diagnosis of CCF between 1993,1994 and 2000,2001. Results:,There were 8359 admissions for CCF in Victoria with an average of 7.37 bed days in 2000,2001. There was a significantly higher admission rate for CCF in rural areas compared to metropolitan in 2000/2001 ,(2.53/1000 (2.44,2.62) and 1.80/1000 (1.75,1.85)) , respectively. Small area analyses identified 17 PCP (14 of which were rural) with significantly higher admission rate ratios of CCF compared to Victoria. Conclusion:,Small area analyses of CCF have identified significant gaps in the management of CCF in the community. This may be a reflection of deficit in primary care availability, accessibility, or appropriateness. Detailed studies may be needed to determine the relative importance of these factors in Victoria for targeting specific interventions at the PCP level. What does this study add?:,Congestive cardiac failure is a major public health problem. In Australia, there is a lack of studies identifying long-term hospitalisation trends of CCF, as well as small area analyses, especially in regard to rural and urban variations. This study has identified significant variations over an eight year period in admission rates of CCF in rural and urban Victoria. Small area analyses (e.g. at the level of primary care partnerships) have identified rural communities with significantly higher admission rates of CCF compared to the Victorian average. For the first time in Australia, this study has provided a new approach for generating evidence on quality of primary care services in rural and urban areas, and offers opportunities for targeting public health and health services interventions that can decrease access barriers, improve the adequacy of primary care, and reduce demand on the hospital system in Victoria. [source] |