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Kinds of Of Areas Selected AbstractsSOM-based estimation of climatic profilesINTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS, Issue 5 2006Tatiana Tambouratzis This article introduces a self-organizing map-based approach for estimating the climatic profile of locations of interest situated within an area of known morphology. The potential of the proposed methodology is illustrated on a number of locations within the Greek territory, and its superiority over other,customarily used as well as novel,climatic profile estimation methodologies is demonstrated and numerically evaluated. It is envisioned that, after further development, the proposed methodology can be employed for creating accurate climatic maps of areas of known morphology. © 2006 Wiley Periodicals, Inc. Int J Int Syst 21: 503,522, 2006. [source] Use of intrauterine devices (IUDs) for contraception in the common chimpanzee (Pan troglodytes)JOURNAL OF MEDICAL PRIMATOLOGY, Issue 2 2000Kenneth G. Gould The common chimpanzee (Pan troglodytes) is a species phylogenetically very close to man. It was not many years ago that the captive population of chimpanzees (P. troglodytes) was considered at risk because of perceived problems with reproductive success. With the potential need for many individuals for research in a variety of areas, particularly in the areas of parasitic and viral infections, an NIH-funded program was established to promote the breeding of the species. That program, the ,National Chimpanzee Breeding and Research Program', was highly successful, so successful, in fact, that there is now a surplus of animals available for current research programs. This situation has prompted the use of intrauterine devices (IUDs) as a method of fertility control. Overall, this method is successful and associated with a failure (of pregnancy) rate similar to that reported in the human. Physical and logistic constraints, however, render the method less than ideal for situations where a pregnancy rate of zero is desired. [source] Personality Disorder Features as Predictors of Symptoms Five Years Post-TreatmentTHE AMERICAN JOURNAL ON ADDICTIONS, Issue 3 2008Irene Jansson MSc Personality disorders are associated with dysfunction in a variety of areas. Recent longitudinal research has shown that personality disorders are also predictive of problems later in life, as well as of poor response to treatment of depression and anxiety. This study assessed whether personality disorder features were associated with psychiatric symptoms in a cohort of women treated for substance abuse in Sweden. Patients were diagnosed with personality disorders using the Structured Clinical Interview for DSM-IV (SCID-II) personality questionnaire and SCID-II interview, and were then administered a self-report questionnaire designed to measure symptoms of psychiatric illness, the Symptoms Checklist-90 (SCL-90), during and five years after treatment. Concurrently, features of all personality disorders, except histrionic, were associated with SCL-90 score. At five-year follow-up, most personality disorders remained associated with SCL-90 score, with the exception of paranoid and schizoid personality disorder. After controlling for baseline score on the SCL-90, conduct disorder, borderline personality disorder, and narcissistic personality disorder remained significantly associated with symptoms at follow-up. After controlling for abstinence and baseline score, only borderline personality disorder features remained associated with SCL-90 score at follow-up. Patients with personality disorders should be monitored after treatment for psychiatric symptoms. [source] An evaluation of two biochemical methods of age determination in insects (pteridines and lipofuscins) using the ant Polyrhachis sexpinosa Latrielle (Hymenoptera: Formicidae)AUSTRALIAN JOURNAL OF ENTOMOLOGY, Issue 2 2009Simon K A Robson Abstract Accurate information on the age of wild-caught animals is valuable for a variety of areas, but can be particularly difficult to obtain for small holometabolous insects, whose body size is fixed at the time of pupal eclosion. A variety of chemical groups, such as lipofuscins and pteridines accumulate in body tissues through time and can be used to predict age in a variety of arthropod taxa. Here we use spectrofluorometry to confirm the presence of extractable levels of lipofuscins and pteridines in individual social insects (using the ant Polyrhachis sexpinosa Latrielle, average body size 25 mg, as an example) and evaluate their ability to predict age. Pteridine levels were independent of age but lipofuscin levels increased with age in a predictable manner (r2 = 72.8%). Lipofuscin levels therefore represent a new method of age determination for social insects that should be applicable to both individual laboratory and wild-caught animals. [source] Engineering Allosteric Regulation into Biological CatalystsCHEMBIOCHEM, Issue 18 2009Jacques Fastrez Prof. Abstract Enzymes and ribozymes constitute two classes of biological catalysts. The activity of many natural enzymes is regulated by the binding of ligands that have different structures than their substrates; these ligands are consequently called allosteric effectors. In most allosteric enzymes, the allosteric binding site lies far away from the active site. This implies that communication pathways must exist between these sites. While mechanisms of allosteric regulation were developed more than forty years ago, they continue to be revisited regularly. The improved understanding of these mechanisms has led in the past two decades to projects to transform several unregulated enzymes into allosterically regulated ones either by rational design or directed evolution techniques. More recently, ribozymes have also been the object of similar successful engineering efforts. In this review, after briefly summarising recent progress in the theories of allosteric regulation, several strategies to engineer allosteric regulations in enzymes and ribozymes are described and compared. These redesigned biological catalysts find applications in a variety of areas. [source] |