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Novel Building Blocks (novel + building_block)
Selected Abstractsdl-BiTOT , A Novel Building Block for Electroactive Oligomers and Polymers in Semiconductor Applications.CHEMINFORM, Issue 39 2002Fredrik von Kieseritzky No abstract is available for this article. [source] Novel Building Blocks: 1-Aryl-2-chloro-1-ethoxyethenes , Preparations and Transformations,EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 3 2007Mitsuhiro Yoshimatsu Abstract We described here a simple method for the preparation of 1-aryl-2-chloro-1-ethoxyethenes 2a,u, which are prodrugs for Alzheimer's disease, by the reaction of dichloroacetaldehyde diethyl acetal with various aryl and alkenyllithium compounds in high yields. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007) [source] Tetrahydropyran-Amino Acids: Novel Building Blocks for Gramicidin-Hybrid Ion ChannelsEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 12 2006Sabine Schröder Abstract The stereoselective synthesis of a cis -2,6-disubstituted tetrahydropyran bearing a ,-amino acid has been achieved starting from N -Boc-leucinal. The THP amino acid was incorporated into peptide sequences and the structural consequences were studied by X-ray crystallography and NMR analysis. Single-channel current measurements showed that the THP amino acid is a suitable substitute for positions 11 and 12 of the gramicidin ion channel. The resulting hybrid ion channel revealed Eisenman I ion selectivity and an ion-dependence of the channel dwell time. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006) [source] Oligomeric Alkoxysilanes with Cagelike Hybrids as Cores: Designed Precursors of Nanohybrid MaterialsCHEMISTRY - AN ASIAN JOURNAL, Issue 3 2008Hideki Kuge Abstract Well-defined alkoxysilane oligomers containing a cagelike carbosiloxane core were synthesized and used as novel building blocks for the formation of siloxane-based hybrid networks. These oligomers were synthesized from the cagelike trimer derived from bis(triethoxysilyl)methane by silylation with mono-, di-, and triethoxychlorosilanes ((EtO)nMe3,nSiCl, n=1, 2, and 3). Hybrid xerogels were prepared by hydrolysis and polycondensation of these oligomers under acidic conditions. The structures of the products varied depending on the number of alkoxy groups (n). When n=2 and 3, microporous xerogels (BET surface areas of 820 and 510,m2,g,1, respectively) were obtained, whereas a nonporous xerogel was obtained when n=1. 29Si,NMR spectroscopic analysis suggested that partial rearrangement of the siloxane networks, which accompanied the cleavage of the Si,O,Si linkages, occurred during the polycondensation processes. By using an amphiphilic triblock copolymer surfactant as a structure-directing agent, hybrid thin films with a 2D hexagonal mesostructure were obtained when n=2 and 3. These results provide important insight into the rational synthesis of molecularly designed hybrid materials by sol,gel chemistry. [source] The Resurgence of Acyclic Nucleic AcidsCHEMISTRY & BIODIVERSITY, Issue 2 2010Su Zhang Abstract This review examines acyclic nucleoside analogs as therapeutic agents, potential progenitor candidates to RNA, and novel building blocks for nucleic-acid nanotechnology. Together, these areas of research provide new insights into the structural and functional properties of nucleic acids and suggest new paradigms for nucleic acid self-assembly. [source] | ||||||||||