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Norwegian Sample (norwegian + sample)
Selected AbstractsAn international multicenter association study of the serotonin transporter gene in persistent ADHDGENES, BRAIN AND BEHAVIOR, Issue 5 2010E. T. Landaas Attention deficit hyperactivity disorder (ADHD) is a common behavioral disorder affecting children and adults. It has been suggested that gene variants related to serotonin neurotransmission are associated with ADHD. We tested the functional promoter polymorphism 5-HTTLPR and seven single nucleotide polymorphisms in SLC6A4 for association with ADHD in 448 adult ADHD patients and 580 controls from Norway. Replication attempts were performed in a sample of 1454 Caucasian adult ADHD patients and 1302 controls from Germany, Spain, the Netherlands and USA, and a meta-analysis was performed also including a previously published adult ADHD study. We found an association between ADHD and rs140700 [odds ratio (OR ) = 0.67; P = 0.01] and the short (S) allele of the 5-HTTLPR (OR = 1.19; P = 0.06) in the Norwegian sample. Analysis of a possible gender effect suggested that the association might be restricted to females (rs140700: OR = 0.45; P = 0.00084). However, the meta-analysis of 1894 cases and 1878 controls could not confirm the association for rs140700 [OR = 0.85, 95% confidence interval (CI) = 0.67,1.09; P = 0.20]. For 5-HTTLPR, five of six samples showed a slight overrepresentation of the S allele in patients, but meta-analysis refuted a strong effect (OR = 1.10, 95% CI = 1.00,1.21; P = 0.06). Neither marker showed any evidence of differential effects for ADHD subtype, gender or symptoms of depression/anxiety. In conclusion, our results do not support a major role for SLC6A4 common variants in persistent ADHD, although a modest effect of the 5-HTTLPR and a role for rare variants cannot be excluded. [source] Symptom management for HIV-positive persons in NorwayINTERNATIONAL NURSING REVIEW, Issue 3 2004E. H. Bunch rn Abstract Purpose:, To record symptoms experienced by people with HIV/AIDS, and describe useful self-care strategies and how symptoms impact on daily life. Method:, A questionnaire was used with self-reported answers and descriptions of how symptoms impact on daily activities and suggestions for useful self-care strategies. Four hundred and twenty-two (n = 422) HIV-positive persons from seven sites in the USA and one site in Norway (n = 20) answered the questionnaire. Results:, In this article subjective symptom descriptions from the Norwegian sample are presented along with self-care strategies and their effectiveness. Findings revealed the Norwegian sample to be a little older, maybe less anxious and depressed, than participants in the larger study. This difference might be explained by the structure of the national social and health care system in Norway, where treatments, medications and social services are available to all citizens without cost. Respondents described a number of related symptoms as well as their subjective explanations of what triggered the symptoms. Most of the self-care strategies were learnt by trial and error. Recommendations:, Community health providers, nurses and physicians should become more knowledgeable about the symptoms that infected persons struggle with, as well as the impact these symptoms have on routine daily self-care activities and a person's quality of life. There is need for more research about helpful self-care strategies to assist HIV-positive persons to manage their symptoms and to disseminate these to community health providers and support groups for HIV infected persons. [source] A cross-national validity study of the Severity Indices of Personality Problems (SIPP-118)PERSONALITY AND MENTAL HEALTH, Issue 1 2009Espen Arnevik Objective,The objective in this study was to test the validity of a new dimensional measure of maladaptive core pathology for personality disorders (PDs), the Severity Indices of Personality Problems (SIPP-118), by comparing a Norwegian sample of 114 patients with PDs with two Dutch samples. In addition, Avoidant PD and Borderline PD were compared, and the relationship between scores on the SIPP-118 and commonly used clinical measures were investigated. Results,The results showed good psychometric properties of the SIPP-118 at the facet level. The Norwegian PD sample had scores equal to the Dutch PD sample and significantly below the general population sample. Correlation with other clinical measures was in the low to moderate range. Conclusion,The cross-national validity of the SIPP-118 was good, and the instrument seems promising as a dimensional instrument for measuring personality pathology. Further research should be undertaken to establish the structure of higher-order domains, its use as a measure of therapeutic change, and its capacity to distinguish Axis II from Axis I pathology. Copyright © 2009 John Wiley & Sons, Ltd. [source] Parent-completed developmental screening in a Norwegian population sample: a comparison with US normative dataACTA PAEDIATRICA, Issue 11 2004H Janson Aim: To compare normative data of a Norwegian translation of the Ages and Stages Questionnaires with original US normative data. Methods: Norwegian-born mothers randomly selected from the population register completed Norwegian translations of the Ages and Stages Questionnaires, a series of 19 age-specific child development screening questionnaires each made up of 30 items in five domains: Communication, Gross Motor, Fine Motor, Problem Solving, and Personal-Social. Domain score group differences with original US normative data on 10 age-specific questionnaires (for ages 4, 8, 12, 16, 20, 24, 30, 36, 48, and 60 mo) were investigated. The Norwegian data consisted of 1341 children, varying between 82 and 176 per age interval. Results: On the whole, parents' reports of their children's development were very similar in the two data sets. Only five out of 50 mean comparisons revealed a mean difference either greater than a Cohen's d of 0.5 or greater than the smallest increment on a domain score. The variation in scores tended to be somewhat smaller in the Norwegian sample. Conclusion: It seems reasonable to expect that domain scores on the Ages and Stages Questionnaires may be interpreted in the same way in Norway and the United States, and these results may also generalize to other Western settings. These findings from a true random sample also increase the confidence in the original normative data. [source] | ||||||||||