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New Lignans (new + lignan)
Selected AbstractsA New Lignan and Four New Lignan Glycosides from Mananthes patentifloraHELVETICA CHIMICA ACTA, Issue 2 2006Junmian Tian Abstract A new lignan, 5-hydroxyjusticidin,A (=,9-(1,3-benzodioxol-5-yl)-5-hydroxy-4,6,7-trimethoxynaphtho[2,3- c]furan-1(3H)-one; 1), and four new diphyllin-type lignan glycosides, mananthosides C,F (2,5), containing glucosyl (Glc), arabinosyl (Ara), galactosyl (Gal), and/or apiosyl residues, have been isolated from Mananthes patentiflora, together with five known compounds. Their structures and configurations were elucidated by in-depth 1D- and 2D-NMR experiments, as well as MS analysis. [source] Three New Arylnaphthalide Lignans from the Aerial Parts of Bupleurum marginatumWall. ex DC.HELVETICA CHIMICA ACTA, Issue 12 2008Ying Liu Abstract Three new arylnaphthalide lignans, 5-(4-hydroxy-3-methoxyphenyl)furo[3,,4,:,6,7]naphtho[2,3- d]-1,3-dioxol-6(8H)-one (1), 10-(4-hydroxy-3-methoxyphenyl)furo[3,,4,:,6,7]naphtho[1,2- d]-1,3-dioxol-9(7H)-one (2), and 10-(3,4-dimethoxyphenyl)-6-hydroxyfuro[3,,4,:,6,7]naphtho[1,2- d]-1,3-dioxol-9(7H)-one (3), together with two known ones, chinensin (4) and isodiphyllin (5), were isolated from the aerial parts of Bupleurum marginatumWall. ex DC. The structures of the three new lignans were established by means of NMR spectroscopic studies, including HQSC, HMBC, and ROESY. [source] Complete assignments of 1H and 13C NMR data for new dibenzocyclooctadiene lignans from Kadsura oblongifoliaMAGNETIC RESONANCE IN CHEMISTRY, Issue 7 2009Hai-Tao Liu Abstract Two new dibenzocyclooctadiene lignans, named kadoblongifolins A (1) and B (2), and one new natural product dibenzocyclooctadiene lignan, named kadoblongifolin C (3), were isolated from the stems of Kadsura oblongifolia (K. oblongifolia), together with five known ones, schizanrin F (4), propinquanin C (5), schisantherin G (6), heteroclitin Q (7), kadsurarin (8). The structures of these new lignans were elucidated by a combination of high-resolution electron ionization mass spectrometry (HR-EI-MS), 1H NMR, 13C NMR, HMQC, HMBC, and NOESY spectra. Copyright © 2009 John Wiley & Sons, Ltd. [source] 1H and 13 C NMR assignments for two lignans from the heartwood of Streblus asperMAGNETIC RESONANCE IN CHEMISTRY, Issue 5 2008Jun Li Abstract In our ongoing investigation of the bioactive constituents from plants, two new lignans, magnolignan A-2- O -,- D -glucopyranoside and strebluslignanol were isolated from heartwood of Streblus asper, along with three known lignans, magnolignan A, magnolol, and magnaldehyde D. 1D and 2D NMR experiments, including COSY, HMQC, and HMBC, and other spectroscopic methods, including UV, IR, and MS were used for the determination of the structures and NMR assignments. Primary bioassays showed that magnolignan A-2- O -,- D -glucopyranoside and strebluslignanol have medium cytotoxic activity against HEp-2 and HepG2 cells, with IC50 of 13.3 µM, 46.4 µM and 10.1 µM, 21.7 µM, respectively. Copyright © 2008 John Wiley & Sons, Ltd. [source] Complete assignments of 1H and 13C NMR data for three new arylnaphthalene lignan from Justicia procumbensMAGNETIC RESONANCE IN CHEMISTRY, Issue 3 2008Guorui Liu Abstract Three new arylnaphthalene lignans, named neojusticin C (1), procumbenoside C (2) and procumbenoside D (3), have been isolated from the whole plant of Justicia procumbens, together with three known ones, justicidinoside B (4), justicidinoside C (5), and diphyllin-1- O -,- D -apiofuranoside (6). The complete assignments of 1H and 13C NMR data for three new lignans were first obtained by means of 2D NMR techniques, including HSQC and HMBC. Copyright © 2008 John Wiley & Sons, Ltd. [source] Complete assignments of 1H and 13C NMR data for seven arylnaphthalide lignans from Justicia procumbensMAGNETIC RESONANCE IN CHEMISTRY, Issue 7 2006Meihua Yang Abstract Three new arylnaphthalide lignans named 6,-hydroxy justicidin A (1), 6,-hydroxy justicidin B (2) and 6,-hydroxy justicidin C (3) have been isolated from the whole plant of Justicia procumbens, together with four known ones, neojusticin A (4), chinensinaphthol methyl ester (5), isodiphyllin (6) and taiwanin C (7). The complete assignments of 1H and 13C NMR chemical shifts for the new lignans and the 13C NMR chemical shifts for the known lignans were obtained for the first time by means of 2D NMR techniques, including HSQC and HMBC. Copyright © 2006 John Wiley & Sons, Ltd. [source] | ||||||||||