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New General Method (new + general_method)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

Development and Application of a New General Method for the Asymmetric Synthesis of (E)-(2-En-3-ynyl)-amines

ADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 3 2009
Chao Yin
Abstract The first direct approach for the asymmetric synthesis of (E)-2-arylidene-1,4-diphenylbut-3-yn-1-amines by addition of alkynylzinc to chiral N - tert -butylsulfinylimines is reported with excellent diastereoselectivity and good yield. This asymmetric addition reaction provides a practical, economical and concise synthesis of multifunctional molecules with the 1,3-enyne side chain and an amino group. In addition, this methodology can be applied to the synthesis of substituted vinyl iodide compounds, and substituted chiral dihydropyrroles. [source]

ChemInform Abstract: A New General Method for the Synthesis of Polyenes Involving 1,6-, 1,8-, 1,10- and 1,12-Carbonyl Group Transpositions via ,-Oxoketene Dithioacetals.

CHEMINFORM, Issue 7 2002
J. Satyanarayana
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: A New General Method for Selective ,-Polynitration of Porphyrins; Preparation and Redox Properties of Zn-Porphyrins Bearing One Through to Eight ,-Nitro Substituents and X-Ray Structure of the First Zn ,-Pernitro Porphyrin.

CHEMINFORM, Issue 2 2001
Magali Palacio
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Application of general formulas for the correction of a lattice-translocation defect in crystals of a lentiviral integrase in complex with LEDGF

ACTA CRYSTALLOGRAPHICA SECTION D, Issue 9 2009
Stephen Hare
The symmetry inherent to many biological macromolecular assemblies has been implicated in a range of crystal pathologies, including lattice-translocation defects (LTDs). Crystals suffering from classic LTDs contain two lattices that are shifted with respect to each other but nonetheless remain within the length of coherent interference. LTD introduces an undesirable intensity modulation into diffraction data, resulting in scrambled or partially scrambled electron densities. In this report, LTD theory is extended and a new general method for determining defect fractions is developed based on the heights of the non-origin peaks observed in native Patterson maps. The application of this method to crystals of lentiviral integrase in complex with its cofactor, where the observed translocation vector does not equal a small integral fraction of a unit-cell edge, is reported and its general application to all classic LTD cases is predicted. [source]