Home About us Contact | |||
New Feature (new + feature)
Selected AbstractsOutcomes Research/Evidence-Based Medicine: A New FeatureDERMATOLOGIC SURGERY, Issue 6 2003Murad Alam MD No abstract is available for this article. [source] Case of the Month: A New Feature for The LaryngoscopeTHE LARYNGOSCOPE, Issue 3 2001Byron J. Bailey MD, Editor No abstract is available for this article. [source] Outlying Charge, Stability, Efficiency, and Algorithmic Enhancements in the Quantum-Mechanical Solvation Method, COSab-GAMESSHELVETICA CHIMICA ACTA, Issue 12 2003Laura In this work, we present algorithmic modifications and extensions to our quantum-mechanical approach for the inclusion of solvent effects by means of molecule-shaped cavities. The theory of conductor-like screening, modified and extended for quantum-mechanical techniques, serves as the basis for our solvation methodology. The modified method is being referred to as COSab-GAMESS and is available within the GAMESS package. Our previous work has emphasized the implementation of this model by way of a distributed multipole approach for handling the effects of outlying charge. The method has been enabled within the framework of open- and closed-shell RHF and MP2. In the present work, we present a) a second method to handle outlying charge effects, b) algorithmic extensions to open- and closed-shell density-functional theory, second-derivative analysis, and reaction-path following, and c) enhancements to improve performance, convergence, and predictability. The method is now surtable for large molecular systems. New features of the enhanced continuum model are highlighted by means of a set of neutral and charged species. Computations on a series of structures with roughly the same molecular shape and volume provides an evaluation of cavitation effects. [source] Introduction to the updated Australian and New Zealand consensus guidelines for the use of antifungal agents in the haematology/oncology setting, 2008INTERNAL MEDICINE JOURNAL, Issue 6b 2008M. A. Slavin Abstract The process for development of these consensus Australasian antifungal guidelines for use in adult patients with haematological malignancy is described. New features included, how the guidelines should be applied, the risk assessment tool used and the grading system for evidence and strength of recommendation are discussed. [source] SmiLib v2.0: A Java-Based Tool for Rapid Combinatorial Library EnumerationMOLECULAR INFORMATICS, Issue 3 2007Andreas Schüller Abstract An updated version of the SMILIB software tool for rapid combinatorial library enumeration was developed. SmiLib v2.0 offers the possibility to construct very large combinatorial libraries using the flexible and portable SMILES format. Libraries were created at rates of approximately 8,700,000 molecules per minute. Combinatorial building blocks are attached to scaffolds by means of linkers rather than to concatenate them directly. This allows for creation of customized libraries using linkers of different sizes and chemical nature. New features are: platform independence, correct handling of stereo chemistry, flexible reaction schemes, improved usability, a unique identifier for each molecule, the option to create libraries in SD format, a conformity check for SmiLib v2.0 SMILES notation restrictions, and decreased library enumeration times. SmiLib v2.0 is available as interactive graphical user interface application and command line tool. [source] New features in 3PPHOTODERMATOLOGY, PHOTOIMMUNOLOGY & PHOTOMEDICINE, Issue 2 2002H. W. Lim M.D. Editor First page of article [source] New features on the fragmentation patterns of homoisoflavonoids in Ophiopogon japonicus by high-performance liquid chromatography/diode-array detection/electrospray ionization with multi-stage tandem mass spectrometryRAPID COMMUNICATIONS IN MASS SPECTROMETRY, Issue 15 2010Jin Qi Homoisoflavonoids, a special class of flavonoids, are mainly distributed in the Liliaceae family and have various biological activities. Previously, very little research has been reported on the gas-phase fragmentation patterns of homoisoflavonoids by electrospray ionization mass spectrometry. In this paper, we report the use of high-performance liquid chromatography with a diode-array detector (HPLC-DAD) and electrospray ionization multi-stage tandem mass spectrometry (ESI-MSn) to study the fragmentation behavior of 11 homoisoflavonoid standards and to analyze homoisoflavonoids in Ophiopogon japonicus. In total, 28 homoisoflavonoids (including seven novel constituents) were characterized. The deprotonated [MH], molecules of the homoisoflavonoids containing a saturated C2C3 bond afforded the A or B product ion (base peak) according to whether the B-ring was substituted with a hydroxyl group. For the homoisoflavonoids containing a C-2C-3 double bond, the product ions (A or C ion) were created from the precursor [MH], ion as the base peak when the B-ring was substituted with a hydroxyl group. The homoisoflavonoids carrying a formyl group in the A-ring readily eliminated one molecule of CO to form the product ion [M,+,HCO], (base peak) irrespective whether the C-2C-3 bond was saturated or not. This product ion afforded the [MHCOB-ringCH2,+,H], ion by cleavage of the C3C9 bond. This latter product ion always appeared in tandem mass (MS/MS) spectra of type I homoisoflavonoids. The common features of flavonoids observed during the gas-phase fragmentation mechanisms were the loss of the following groups: 15,Da (CH3), 18,Da (H2O), 28,Da (CO), 44,Da (CO2) and 46,Da (CH2O2). A retro-Diels-Alder (RDA)-like cleavage was also observed for the homoisoflavonoids. The different gas-phase fragmentation routes were characterized for the deprotonated molecules obtained from the various homoisoflavonoids and collision-induced dissociation (CID) fragmentation differences were noted for the different locations of the various substituents. In conclusion, we can say that this study allowed us to structurally elucidate and identify homoisoflavonoids distributed in related plants and their complex prescriptions. Copyright © 2010 John Wiley & Sons, Ltd. [source] An interactive simulation tool for image registration educationCOMPUTER APPLICATIONS IN ENGINEERING EDUCATION, Issue 2 2010Khaled M. Gharaibeh Abstract A medical image registration simulation toolkit built using MATLAB graphical user interface (GUI) is presented. The developed Matlab GUI's provide an effective tool for exploring different image registration techniques including a new feature-based image registration technique proposed by the authors. The toolkit is useful for biomedical engineering students and can be used as a web-based learning tool. © 2009 Wiley Periodicals, Inc. Comput Appl Eng Educ 18: 225,237, 2010; Published online in Wiley InterScience (www.interscience.wiley.com); DOI 10.1002/cae.20179 [source] Books received by the editorHYDROLOGICAL PROCESSES, Issue 4 2003Article first published online: 18 FEB 200 Comments by, and interviews with, authors, editors, and others responsible for carefully and dutifully shepherding intellecutal thoughts into published text will soon appear in this section. Dr. Jeff J. McDonnell, editor of HPToday, has approved the inclusion of this new feature. The rational in this decision to forgo a critical second opinion on the value of the book stems from our observation that books received by HPToday have often been reviewed by other respectable press (e.g., NY Times Book Review, Science Book Review, etc.), and a more unique angle might interest Hydrological Processes readers. The first group of authors has responded favourably to the notion of explaining their inspirations and frustrations and intentions in creating a published work. Please keep coming back to read more about the hydrological field! Copyright © 2003 John Wiley & Sons, Ltd. [source] Books received by the editorHYDROLOGICAL PROCESSES, Issue 1 2003Article first published online: 19 DEC 200 Comments by, and interviews with, authors, editors, and others responsible for carefully and dutifully shepherding intellecutal thoughts into published text will soon appear in this section. Dr. Jeff J. McDonnell, editor of HPToday, has approved the inclusion of this new feature. The rational in this decision to forgo a critical second opinion on the value of the book stems from our observation that books received by HPToday have often been reviewed by other respectable press (e.g., NY Times Book Review, Science Book Review, etc.), and a more unique angle might interest Hydrological Processes readers. The first group of authors has responded favourably to the notion of explaining their inspirations and frustrations and intentions in creating a published work. Please keep coming back to read more about the hydrological field! Copyright © 2003 John Wiley & Sons, Ltd. [source] Books received by the editorHYDROLOGICAL PROCESSES, Issue 17 2002Article first published online: 21 NOV 200 Comments by, and interviews with, authors, editors, and others responsible for carefully and dutifully shepherding intellecutal thoughts into published text will soon appear in this section. Dr. Jeff J. McDonnell, editor of HPToday, has approved the inclusion of this new feature. The rational in this decision to forgo a critical second opinion on the value of the book stems from our observation that books received by HPToday have often been reviewed by other respectable press (e.g., NY Times Book Review, Science Book Review, etc.), and a more unique angle might interest Hydrological Processes readers. The first group of authors has responded favourably to the notion of explaining their inspirations and frustrations and intentions in creating a published work. Please keep coming back to read more about the hydrological field! Copyright © 2002 John Wiley & Sons, Ltd. [source] Matched interface and boundary (MIB) method for the vibration analysis of platesINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, Issue 9 2009S. N. Yu Abstract This paper proposes a novel approach, the matched interface and boundary (MIB) method, for the vibration analysis of rectangular plates with simply supported, clamped and free edges, and their arbitrary combinations. In previous work, the MIB method was developed for three-dimensional elliptic equations with arbitrarily complex material interfaces and geometric shapes. The present work generalizes the MIB method for eigenvalue problems in structural analysis with complex boundary conditions. The MIB method utilizes both uniform and non-uniform Cartesian grids. Fictitious values are utilized to facilitate the central finite difference schemes throughout the entire computational domain. Boundary conditions are enforced with fictitious values,a common practice used in the previous discrete singular convolution algorithm. An essential idea of the MIB method is to repeatedly use the boundary conditions to achieve arbitrarily high-order accuracy. A new feature in the proposed approach is the implementation of the cross derivatives in the free boundary conditions. The proposed method has a banded matrix. Nine different plates, particularly those with free edges and free corners, are employed to validate the proposed method. The performance of the proposed method is compared with that of other established methods. Convergence and comparison studies indicate that the proposed MIB method works very well for the vibration analysis of plates. In particular, modal bending moments and shear forces predicted by the proposed method vanish at boundaries for free edges. Copyright © 2008 John Wiley & Sons, Ltd. [source] Projective virtual reality as a basis for on-line control of complex systems-not only-over the internetJOURNAL OF FIELD ROBOTICS (FORMERLY JOURNAL OF ROBOTIC SYSTEMS), Issue 3 2005Eckhard Freund Already in 1994 the term Projective Virtual Reality was coined and a first implementation was used to control a complex multirobot system in Germany over the Internet from California. Building on this foundation, the general aim of the development of virtual reality technology for automation applications at the Institute of Robotics Research (IRF) today is to provide the framework for Projective Virtual Reality for a broad range of applications. The general idea of Projective Virtual Reality is to allow users to "project" actions carried out in the virtual world into the real world by means of robots or other means of automation. The framework is based on a task-oriented approach which builds on the "task deduction" capabilities of a newly developed virtual reality system and a task planning component. The advantage of this approach is that robots which work at great distances from the control station can be controlled as easily and intuitively as robots that work right next to the control station. Robot control technology now provides the user in the virtual world with a "prolonged arm" into the physical environment, thus paving the way for intuitive control of complex systems over the Internet,and in general for a new quality of user-friendly man-machine interfaces for automation applications. Lately, this work has been enhanced by a new structure that allows one to distribute the virtual reality application over multiple computers on a network. With this new feature, it is now possible for multiple users to share the same virtual room, although they may physically be thousands of miles apart. They only need an Internet connection to share this new experience. Lately, the network distribution techniques have been further developed to not just allow users to cooperate over networked PCs but also to be able to set up a panorama projection or a cave running of a networked cluster of PCs. This approach cuts down the costs for such a high-end visualization environment drastically and allows for a new range of applications. © 2005 Wiley Periodicals, Inc. [source] Credit cards scoring with quadratic utility functionsJOURNAL OF MULTI CRITERIA DECISION ANALYSIS, Issue 4-5 2002Vladimir Bugera Abstract The paper considers a general approach for classifying objects using mathematical programming algorithms. The approach is based on optimizing a utility function, which is quadratic in indicator parameters and is linear in control parameters (which need to be identified). Qualitative characteristics of the utility function, such as monotonicity in some variables, are included using additional constraints. The methodology was tested with a ,credit cards scoring' problem. Credit scoring is a way of separating specific subgroups in a population of objects (such as applications for credit), which have significantly different credit risk characteristics. A new feature of our approach is incorporating expert judgments in the model. For instance, the following preference was included with an additional constraint: ,give more preference to customers with higher incomes.' Numerical experiments showed that including constraints based on expert judgments improves the performance of the algorithm. Copyright © 2003 John Wiley & Sons, Ltd. [source] Pseudo Crosstalk Behavior in a Patient with Atrio-ventricular Block and Implanted Biventricular DefibrillatorPACING AND CLINICAL ELECTROPHYSIOLOGY, Issue 12 2007REGINALD T. HO M.D. We present a 59-year-old man with a dilated cardiomyopathy (ejection fraction = 20%), congestive heart failure and atrio-ventricular (AV) block who underwent implantation of a biventricular defibrillator (BiV ICD). While undergoing cardiac transplant evaluation for drug-refractory ventricular fibrillation, his telemetry recorded findings resembling crosstalk inhibition. Device interrogation was normal. All episodes occurred at 1:00 a.m. suggesting a routine device operation. Left ventricular capture management, a new feature that automatically measures left ventricular pacing thresholds at 1:00 a.m., had been programmed to Monitor. Understanding this sophisticated pacing algorithm might avoid confusion when operative in patients with AV block. [source] Ethmoid mucocele: A new feature of primary ciliary dyskinesiaPEDIATRIC PULMONOLOGY, Issue 2 2010Marco Berlucchi MD Abstract Primary ciliary dyskinesia (PCD) is a rare congenital autosomal recessive disease that produces impairment of mucosal ciliary movement. Children with this disorder usually manifest recurrent and chronic infections of the upper and lower airways. We describe the history of a 12-month-old boy in whom the correct diagnosis of PCD was achieved after the occurrence of ethmoid mucocele associated with omolateral proptosis. A careful description of this new feature of PCD and its dangerous complications are also presented. Pediatr Pulmonol. 2010; 45:197,201. ©2009 Wiley-Liss, Inc. [source] Atomic model of human Rcd-1 reveals an armadillo -like-repeat protein with in vitro nucleic acid binding propertiesPROTEIN SCIENCE, Issue 2 2007Robert G. Garces Abstract Rcd-1, a protein highly conserved across eukaryotes, was initially identified as a factor essential for nitrogen starvation-invoked differentiation in fission yeast, and its Saccharomyces cerevisiae homolog, CAF40, has been identified as part of the CCR4,NOT transcription complex, where it interacts with the NOT1 protein. Mammalian homologs are involved in various cellular differentiation processes including retinoic acid-induced differentiation and hematopoetic cell development. Here, we present the 2.2 Å X-ray structure of the highly conserved region of human Rcd-1 and investigate possible functional abilities of this and the full-length protein. The monomer is made up of six armadillo repeats forming a solvent-accessible, positively-charged cleft 21,22 Å wide that, in contrast to other armadillo proteins, stays fully exposed in the dimer. Prompted by this finding, we established that Rcd-1 can bind to single- and double-stranded oligonucleotides in vitro with the affinity of G/C/T , A. Mutation of an arginine residue within the cleft strongly reduced or abolished oligonucleotide binding. Rcd-1's ability to bind to nucleic acids, in addition to the previously reported protein,protein interaction with NOT1, suggests a new feature in Rcd-1's role in regulation of overall cellular differentiation processes. [source] Observations of cross-ridge flows across steep terrainTHE QUARTERLY JOURNAL OF THE ROYAL METEOROLOGICAL SOCIETY, Issue 633 2008H. W. Lewis Abstract A field experiment, Gaudex, has been conducted to address the need for quantitative measurements of turbulence in the vicinity of steep terrain. A dense network of automatic weather stations and turbulence towers was deployed along cross-ridge transects over Gaudergrat, a steep triangular cross-section ridge in eastern Switzerland. A new feature, whereby ridge-normal cross-ridge flows develop at the crest even when the flow in each valley is oriented parallel to the ridge axis, is identified. This occurs independently of whether the flow is thermally or synoptically driven. Pressure measurements across the ridge show that this flow is driven by a cross-ridge pressure gradient. Two mechanisms for generating cross-ridge flows have been identified from measurements of pressure, wind and temperature. In most cases the pressure gradient arises from a difference in flow speeds between the two sides of the ridge, caused by different valley geometries. Less commonly, the cross-ridge flow is explained by linear speed-up of the ridge-normal flow. Copyright © 2008 Royal Meteorological Society [source] Editors' Choice: ChemInform 31/2010CHEMINFORM, Issue 31 2010Article first published online: 9 JUL 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 28/2010CHEMINFORM, Issue 28 2010Article first published online: 17 JUN 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 25/2010CHEMINFORM, Issue 25 2010Article first published online: 27 MAY 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 23/2010CHEMINFORM, Issue 23 2010Article first published online: 18 MAY 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 22/2010CHEMINFORM, Issue 22 2010Article first published online: 12 MAY 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 20/2010CHEMINFORM, Issue 20 2010Article first published online: 22 APR 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 18/2010CHEMINFORM, Issue 18 2010Article first published online: 9 APR 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 17/2010CHEMINFORM, Issue 17 2010Article first published online: 1 APR 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 14/2010CHEMINFORM, Issue 14 2010Article first published online: 11 MAR 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 13/2010CHEMINFORM, Issue 13 2010Article first published online: 5 MAR 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 11/2010CHEMINFORM, Issue 11 2010Article first published online: 19 FEB 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] Editors' Choice: ChemInform 10/2010CHEMINFORM, Issue 10 2010Article first published online: 11 FEB 2010 ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading chemistry journals. As a new feature, the ChemInform Editors offer their personal research highlights of the week, in the form of a regular ChemInform Abstract. To access the Editors' Choice Abstract, please select the PDF Full-text option. The original article presented in Editors' Choice is trackable via the "References" option. [source] |