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New Episode (new + episode)
Selected AbstractsPsychopathology is associated with dyspeptic symptom severity in primary care patients with a new episode of dyspepsiaALIMENTARY PHARMACOLOGY & THERAPEUTICS, Issue 5 2009S. MUJAKOVIC Summary Background, Personality and psychiatric disorders are reported to be more common in dyspeptic patients with severe complaints, but it remains unclear whether this association exists for patients with mild and moderate dyspepsia. Aim, To study the association between dyspeptic symptom severity and psychopathology, major life events and coping ability in patients with a new episode of dyspepsia. Methods, Dyspeptic symptom severity was measured using the validated eight symptom Veldhuyzen van Zanten questionnaire. Psychopathology was measured using the Symptom Check List-90 (SCL 90). Major life events were measured with a modified version of the Social Readjustment Rating Scale (SRRS). Coping styles were measured by a short version of the Utrecht Coping Questionnaire, distinguishing six coping styles. Linear regression was used to assess the relationship between dyspepsia symptom severity and psychological factors. Results, In all, 664 patients with a new episode of uninvestigated dyspepsia, aged >18 years were included. Dyspeptic symptom severity was positively correlated with the presence of depression (P < 0.01), somatization symptoms (P < 0.01), use of an active coping style (P < 0.01) and negatively correlated with age (P < 0.01). Conclusions, Primary care patients consulting with dyspepsia have higher levels of depression and somatization especially at younger age. An active coping style is associated with dyspepsia symptom severity. [source] Prediction of first episode of panic attack among white-collar workersPSYCHIATRY AND CLINICAL NEUROSCIENCES, Issue 2 2005AKIRA WATANABE md Abstract, The purpose of the present study was to elucidate a longitudinal matrix of the etiology for first-episode panic attack among white-collar workers. A path model was designed for this purpose. A 5-year, open-cohort study was carried out in a Japanese company. To evaluate the risk factors associated with the onset of a first episode of panic attack, the odds ratios of a new episode of panic attack were calculated by logistic regression. The path model contained five predictor variables: gender difference, overprotection, neuroticism, lifetime history of major depression, and recent stressful life events. The logistic regression analysis indicated that a person with a lifetime history of major depression and recent stressful life events had a fivefold and a threefold higher risk of panic attacks at follow up, respectively. The path model for the prediction of a first episode of panic attack fitted the data well. However, this model presented low accountability for the variance in the ultimate dependent variables, the first episode of panic attack. Three predictors (neuroticism, lifetime history of major depression, and recent stressful life events) had a direct effect on the risk for a first episode of panic attack, whereas gender difference and overprotection had no direct effect. The present model could not fully predict first episodes of panic attack in white-collar workers. To make a path model for the prediction of the first episode of panic attack, other strong predictor variables, which were not surveyed in the present study, are needed. It is suggested that genetic variables are among the other strong predictor variables. A new path model containing genetic variables (e.g. family history etc.) will be needed to predict the first episode of panic attack. [source] Nonverbal behavioral similarity between patients with depression in remission and interviewers in relation to satisfaction and recurrence of depressionDEPRESSION AND ANXIETY, Issue 4 2006Erwin Geerts Ph.D. Abstract Unsatisfying interpersonal relationships are involved in the onset and course of depression. However, little is known about the underlying mechanisms. In this study we investigated the nonverbal communication between 101 patients with remitted depression and interviewers. We related the interaction between the patients' and interviewers' behavior to patients' satisfaction with the interview and to the risk of recurrence of depression. We registered the patients' and interviewers' nonverbal displays of involvement during a clinical interview and assessed the patients' satisfaction with the interview. Possible recurrence of depression was assessed within a 2-year follow-up. Based on findings in healthy people, we hypothesized that the more similar the levels of the patients' and interviewers' behavior became during the interview, the more satisfied the patients would turn out to be. Furthermore, we hypothesized that lack of similarity in the levels of the patients' and interviewers' involvement behavior would predict recurrence of depression. Our hypotheses were confirmed: The more the patients' and interviewers' behavior converged, the more satisfied the patients were with the interview and the lower the risk of recurrence of depression. Satisfaction did not mediate the association between convergence and risk of recurrence. Also, no gender effects were found. We conclude that nonverbal communication processes are involved in the risk of recurrence of depression. Remitted people's difficulties in reaching nonverbal convergence with others may hamper them in their interpersonal functioning and, as a consequence, may put them at risk for new episodes of depression. Depression and Anxiety 23:200,209, 2006. © 2006 Wiley-Liss, Inc. [source] The basis for treatment in multiple sclerosisACTA NEUROLOGICA SCANDINAVICA, Issue 2006A. Compston Contemporary licensed treatments for multiple sclerosis fail to provide a solution for the disease because their effects are limited to a modest reduction in the frequency of new episodes. They do not reduce disability or materially influence the progressive phase of the disease. A contemporary strategy for management requires a more detailed analysis of the separate contributions to the clinical features and overall course made by inflammation, axonal injury, compensatory mechanisms, and remyelination. From this formulation emerges the need either for early and fully effective suppression of the inflammatory response, limiting the damage to all components of the axon-glial unit; or the development of strategies for axonal and myelin repair that solve the issues of controlled differentiation, delivery and timing of these cell and growth factor-based interventions. [source] | ||||||||||