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New C2 (new + c2)
Selected AbstractsConvenient synthesis of c2 -symmetric diazepinium salts derived from 1,1,-binaphthyl-2,2,-diamineJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 1 2007Wolfgang A. Herrmann New C2 -symmetric atropisomeric diazepinium salts were prepared utilizing Vilsmeier-Haack activation of corresponding formamide precursors by phosgene solution in toluene. The structures of these substances were verified by X-ray diffraction. [source] New C2 -Symmetric Diphosphite Ligands Derived from Carbohydrates: Effect of the Remote Stereocenters on Asymmetric Catalysis.CHEMINFORM, Issue 51 2007M. Rosa Axet Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis of New C2 -Symmetrical Bis(hydroxycamphorsulfonamide) Ligands and Their Application in the Enantioselective Addition of Dialkylzinc Reagents to Aldehydes and Ketones.CHEMINFORM, Issue 36 2003Miguel Yus Abstract For Abstract see ChemInform Abstract in Full Text. [source] Asymmetric Epoxidation of Aldehydes Catalyzed by New C2 -Symmetrical Chiral Sulfide.CHEMINFORM, Issue 48 2002Miyuki Ishizaki Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: New C2 -Symmetric Chiral Disulfide Ligands Derived from (R)-Cysteine.CHEMINFORM, Issue 30 2001Antonio L. Braga Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: New C2 -Symmetrical 1,2-Diphosphanes for the Efficient Rhodium-Catalyzed Asymmetric Hydroboration of Styrene Derivatives.CHEMINFORM, Issue 30 2001Stephane Demay Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Oxidative coupling of acridinones: Synthesis of new C2 -symmetry atropisomersJOURNAL OF HETEROCYCLIC CHEMISTRY, Issue 1 2008Karine Scarpellini-Charras The preparation of symmetric 2,2,-dimethoxy-10,10,-biacridinyl-9,9,-dione atropisomers were obtained by the oxidative coupling of 9(10H)-acridinone with 1,3-dibromo-5,5-dimethyl-imidazolidine-2,4-dione [source] 3D-QSAR Studies on C24-Monoalkylated Vitamin D3 26,23-Lactones and their C2, -Modified Derivatives with Inhibitory Activity to Vitamin D ReceptorMOLECULAR INFORMATICS, Issue 8-9 2010Jinhu Wang Abstract The ligand-based three-dimensional quantitative structure-activity relationship (3D-QSAR) for 82 inhibitors of 25-dehydro-1, -hydroxyvitamin D3 -26,23-lactone analogs has been studied by using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) models. The established CoMFA model in training set gives a cross-validated q2 value of 0.516 and a non-cross-validated rncv2 value of 0.667, while the CoMSIA model results in q2=0.517 and rncv2=0.632. In general, the predictive ability of the CoMFA model is superior to that of the CoMSIA model, with rpred2=0.639 for the CoMFA and rpred2=0.619 for the CoMSIA model. Based on the CoMFA contour maps, some key structural characters of vitamin D3 analogs responsible for inhibitory activity are identified, and some new C2, -modified 24-alkylvitamin D3 lactone analogs with high predicted pIC50 values are designed. The ligand functional group mutations by FEP simulation and docking studies reveal the rationality of the molecular design. [source] | ||||||||||