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Neuropsychological Findings (neuropsychological + finding)

Distribution by Scientific Domains

Psychology	50%
Medical Sciences	50%

Selected Abstracts

Familial dyslexia: neurocognitive and genetic correlation in a large Finnish family

DEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 9 2002
Jaana Nopola-Hemmi MD
Neuropsychological findings of individuals with dyslexia (n=24) from a large, three-generation Finnish family are presented. We have previously performed whole genome linkage scanning in this family and found that dyslexia in this kindred segregates with a single locus in the pericentromeric area of chromosome 3. Those included in the analyses were carefully evaluated for general cognitive ability, reading and spelling skills, and reading-related neurocognitive skills. The neurocognitive type of dyslexia segregating in this family consisted of deficits in phonological awareness, verbal short-term memory, and rapid naming. Severe dyslexia also seemed to be connected with a general language difficulty and was most common in the eldest generation. [source]

Neuropsychological studies in anorexia nervosa

INTERNATIONAL JOURNAL OF EATING DISORDERS, Issue S1 2005
Kate Tchanturia PhD
Abstract Neuropsychological findings in eating disorders are somewhat inconsistent. This may be because individual studies have used a broad range of tests on relatively small, heterogeneous clinical groups, thus limiting the detection of subtle neuropsychological differences in these patients. Therefore, rather than using broad assessments of a variety of neuropsychological functions, adoption of a more focused, hypothesis-driven approach based on clinical practice is proposed. This will allow more in-depth investigations of targeted functions and will improve the chances of detecting a problem, of exploring its ecologic validity, and of tailoring a treatment. We have demonstrated this approach using our neuropsychological studies of cognitive flexibility in anorexia nervosa (AN). © 2005 by Wiley Periodicals, Inc. [source]

Do patients with psychogenic nonepileptic seizures produce trustworthy findings on neuropsychological tests?

EPILEPSIA, Issue 4 2008
Carl B. Dodrill
Summary Drane et al. (2006) has recently raised the possibility that patients with psychogenic nonepileptic seizures (PNES) may make poor effort in taking neuropsychological tests in comparison with patients with epilepsy (ES). Therefore, findings previously reported with PNES patients may be in error, especially with regard to tests of mental abilities. Using the same measure of effort used by Drane et al. (2006) but with more broadly selected patients, this paper attempts to replicate their findings with new samples of ES (n = 65) and PNES (n = 32) cases. However, their findings could not be replicated, and no differences in test taking effort could be demonstrated across the groups. The highly selected samples of Drane et al. (2006) appear to be responsible for their results, and neuropsychological findings with PNES patients appear to be as trustworthy as those with ES patients. [source]

Cognitive remediation therapy as an intervention for acute anorexia nervosa: a case report

EUROPEAN EATING DISORDERS REVIEW, Issue 5 2005
Helen Davies
Abstract The aim of this case report is to illustrate how cognitive remediation therapy (CRT) can be used as part of the treatment programme in acute anorexia nervosa (AN) to stimulate mental activities and improve thinking skills and information-processing systems when other therapies, for example cognitive behavioural therapy (CBT), may be too complex and intense for the patient to engage in. Furthermore, we hypothesize that CRT may be an effective tool in improving flexibility of thinking in AN, as previous neuropsychological findings have proved that rigidity is one of the maintaining factors in AN. Copyright © 2005 John Wiley & Sons, Ltd and Eating Disorders Association. [source]

99mTc-ethyl cysteinate dimer brain SPECT findings in early stage of dementia with Lewy bodies and Parkinson's disease patients: a correlation with neuropsychological tests

EUROPEAN JOURNAL OF NEUROLOGY, Issue 1 2008
C.-C. Chang
We examined clinical presentations, neuropsychological findings, and perfusion patterns of 99mTc-ethyl cysteinate dimer (ECD) single photon emission computed tomography (SPECT) in patients with early stage dementia with Lewy bodies (DLB) (n = 17) and Parkinson's disease (PD) (n = 16), with age-matched healthy controls (n = 10). Seven paired regions of interest (ROIs) were drawn manually including inferior frontal, temporal, parietal, occipital, parieto-occipital junction, striatum and thalamus for semiquantitative measurement. Neuropsychological tests were applied for clinical correlation. The SPECT results showed significant hypoperfusion in DLB group in frontal, parietal, thalamus, temporal ROIs compared with controls (P < 0.01) whilst signals in temporal areas was significantly reduced compared with PD group (P < 0.05). Neuropsychological tests showed that DLB patients had deficits in mental manipulation, short-term memory, abstract thinking, drawing and semantic verbal fluencies (P < 0.05, compared with control). In addition, DLB group had lower scores than those with PD in mental manipulation, drawing and semantic verbal fluency (P < 0.05). Our study showed that even in early stages of DLB, neuropsychological and perfusion patterns were evident and may be different from PD group, despite they shared certain similarities both in neuropsychological and image findings compared with age-matched controls. [source]

Subjective cognitive complaints, neuropsychological performance, affective and behavioural symptoms in non-demented patients

INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 1 2008
Roberto Gallassi
Abstract Objective Subjective cognitive complaints (SCC) have been previously investigated to establish whether they are risk factors for dementia, but no clear-cut conclusions have emerged. In this study non-demented patients with SCC were studied and the neuropsychological findings, affective and behavioural aspects and parameters with the highest correct classifications in discriminating patients who had only SCC but no objective clinical and neuropsychological impairment, i.e. no cognitive impairment (NCI) patients and those with objective neuropsychological deficits, namely patients with mild cognitive (MCI) were analyzed. Methods Consecutive non-demented outpatients with SCC were enrolled of over 9 months and examined using neuropsychological tests and scales for depression, anxiety and behaviour. Clinical criteria and neuropsychological test results were used to classify patients into groups of NCI, MCI and subtypes of MCI. Results Ninety-two patients with SCC were included; 49 of them had objective deficits (MCI patients), whereas 43 were without any clinical and cognitive impairment (NCI patients). These patients had lower age, higher education and better general cognitive indices than MCI patients who had higher caregiver distress, depression and irritability. The combination of a battery for mental deterioration and for behavioural memory assessment were the most discriminative in differentiating the two groups. Conclusions An objective cognitive impairment, reaching the criteria for a MCI diagnosis, was present in almost half of patients having SCC. MCI patients have more behavioural disturbances than NCI subjects. SCC should not be underestimated and appropriate neuropsychological assessment is required to reassure subjects with normal results and to identify patients with MCI. Copyright © 2007 John Wiley & Sons, Ltd. [source]

Action-oriented representation of peripersonal and extrapersonal space: Insights from manual and locomotor actions1

JAPANESE PSYCHOLOGICAL RESEARCH, Issue 3 2006
TAKAHIRO HIGUCHI
Abstract:, This paper reviews behavioral evidence demonstrating that space is accurately represented in the brain in relation to action capabilities. We initially review intriguing neuropsychological findings that show that space is differentially represented depending on whether the area is in reach of the hand (peripersonal space) or out of reach of the hand (extrapersonal space). We then review the literature on the characteristics of locomotor actions for avoiding obstacles to show that the relative dimensions of obstacles to relevant body parts are accurately represented at least one step before the obstacles are reached, i.e., while the obstacles are present in the extrapersonal space. The findings obtained from a number of studies on manual and locomotor actions will yield tentative conclusions: (a) the representation of one's body (body schema) is deeply involved in one's representation of space; (b) the representation of space is modified in response to alteration of action capabilities, although this is likely to occur only for well-learned actions, irrespective of the type; and (c) representation of space centered on the hand somewhat differs from that centered on the whole body. [source]

A Tale of Two Cases: Lessons for Education From the Study of Two Boys Living With Half Their Brains

MIND, BRAIN, AND EDUCATION, Issue 2 2007
Mary Helen Immordino-Yang
ABSTRACT, In recent years, educators have been looking increasingly to neuroscience to inform their understanding of how children's brain and cognitive development are shaped by their learning experiences. However, while this new interdisciplinary approach presents an unprecedented opportunity to explore and debate the educational implications of neuropsychological research, a good model for this dialogue is lacking. This is in part because relatively little is known about the relationships between cognitive, emotional, and neurological development, in part because of a dearth of research methods designed to rigorously connect issues of learning and development to neuropsychological strengths and weaknesses, and in part because neuropsychological studies are rarely presented in a format that is conducive to meaningful cross-disciplinary dialogue with educators. To begin to address these issues, in this article, I present the complementary cases of Nico and Brooke, two high-functioning adolescents, who have suffered the removal of an entire brain hemisphere (Nico his right and Brooke his left) to control severe epilepsy. Through presenting a neuropsychological study of these rare boys' emotion and affective prosody (vocal intonation) through the developmental lens of an educator, I reinterpret the neuropsychological findings for what they reveal about how the boys leveraged their emotional and cognitive strengths to learn important skills for which they were each missing half of the normally recruited neural hardware. While Nico's and Brooke's results seem on the surface to contradict expectations based on neuropsychological findings with adults, they combine to reveal a compensatory logic that begins to elucidate the active role of the learner as well as the organizing role of emotion in brain development, providing a jumping-off point for discussion between educators and neuroscientists and a model for connecting neuropsychological strengths and weaknesses to learning. [source]