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Nasal Patency (nasal + patency)

Distribution by Scientific Domains

Medical Sciences	100%

Selected Abstracts

Does inhaling menthol affect nasal patency or cough?,

PEDIATRIC PULMONOLOGY, Issue 6 2008
MRCPCH, Priti Kenia MD (Paediatrics)
Abstract Objective There is widespread use of menthol in over-the-counter medications, despite scant information on any beneficial effects. Our aim was to assess the effect of menthol on nasal air flow, perception of nasal patency and cough challenge testing. Materials and Methods Subjects comprised 42 healthy children aged 10 and 11 in a school setting. We used a single-blind pseudo-randomized cross-over trial to compare the effect of an inhalation of either menthol or placebo(eucalyptus oil). Baseline and post-intervention measurements were made on each of 2 consecutive days. Main outcome measures were (i) nasal expiratory and inspiratory flows and volumes, measured by spirometer, (ii) perception of nasal patency, assessed with a visual analogue scale (VAS), and (iii) the number of coughs in response to nebulized citric acid. Results There was no effect of menthol on any of the spirometric measurements. Following menthol, there was a significant increase in the perception of nasal patency (mean difference in log VAS (menthol-placebo),=,,0.207, 95%CI ,0.329, ,0.085). The cough count after menthol inhalation was reduced when compared to baseline but the change was not different from that after placebo (mean difference in cough count (menthol-placebo),=,,1.71, 95%CI ,4.11, 0.69). Conclusion Menthol has no effect on objective measures of flow but significantly increases the perception of nasal patency. It may not be possible to extrapolate these findings to younger children and those with rhinitis. Extending the study of menthol to these groups, including investigations of the efficacy and safety profiles, will provide further valuable evidence for its common use. Pediatr Pulmonol. 2008; 43:532,537. © 2008 Wiley-Liss, Inc. [source]

The association of subjective nasal patency with peak inspiratory nasal flow in a large healthy population

CLINICAL OTOLARYNGOLOGY, Issue 4 2003
J. Jose
The association of subjective nasal patency with peak inspiratory nasal flow in a large healthy population This study, performed on 303 healthy volunteers, tested the null hypothesis that normal subjects were unable to assess their nasal patency when compared with objective measurement using peak inspiratory nasal flow rate (PINFR). Subjective assessments were made on a categorical scale and PINFR was measured using an In-Check meter. Analysis of variance showed that the peak inspiratory nasal flow rate, when grouped by the subjective scores, was significantly different. [source]