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Nanofibrous Membrane (nanofibrou + membrane)

Distribution by Scientific Domains
Polymers and Materials Science100%

Selected Abstracts

Electrospun PEG,PLA nanofibrous membrane for sustained release of hydrophilic antibiotics

JOURNAL OF APPLIED POLYMER SCIENCE, Issue 1 2010
Xiuling Xu
Abstract Reported in this study is the successful incorporation of a hydrophilic antibiotic drug, tetracycline hydrochloride (TCH), into electrospun PEG,PLA nanofibrous membrane without loss of its bioactivity. Degradation behavior of the copolymer was studied in vitro. Release behavior of TCH from the electrospun membrane and antimicrobial effects of the TCH-loaded membrane against Staphylococcus aureus culture were investigated. The medicated nanofibrous membrane demonstrated sustained release of TCH over 6 days and was found to be effective in inhibiting growth of S. aureus. In addition, increasing the antibiotic drug content in the electrospun membranes was found to enhance the anti-bacterial effectiveness of the medicated fiber mats. And the combination of mechanical barriers provided by the electrospun biodegradable nanofibrous membranes and their capability of local sustained delivery of antibiotics made these membranes more useful in biomedical applications, particularly as new wound dressings for ulcers caused by diabetes or other diseases, and to provide a better means of treatment for these malignant wounds and ulcers. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010 [source]

Ionic-Strength- and pH-Responsive Poly[acrylamide- co -(maleic acid)] Hydrogel Nanofibers

MACROMOLECULAR CHEMISTRY AND PHYSICS, Issue 8 2007
Haiqing Liu
Abstract A novel acrylamide/maleic acid copolymer [P(AM-MA)] hydrogel nanofibrous membrane with a fiber diameter of ca. 120 nm is prepared by electrospinning an aqueous P(AM-MA) solution with diethylene glycol as crosslinker, followed by a heat-induced esterification crosslinking reaction at 145,°C. This hydrogel nanofiber can maintain a fiber form, but becomes distorted and merges to form many physical crosslinking points after immersion in water. The P(AM-MA) hydrogel nanofibers are sensitive to external stimuli ionic strength and pH. Their water-swelling ratio decreases with increasing solution ionic strength, and it shows a characteristic two-step increase at pH,=,2.5 and 8.5 in response to the increase of solution pH. The maximum water-swelling ratios of the P(AM-MA) hydrogel nanofibers are 18.1 and 22.5 g,·,g,1 in a solution of 0.05 mol,·,dm,3 ionic strength and in an aqueous solution of pH 11, respectively. [source]

Preparation of Water-Absorbing Polyacrylonitrile Nanofibrous Membrane

MACROMOLECULAR RAPID COMMUNICATIONS, Issue 2 2006
Haiqing Liu
Abstract Summary: Hydrophilic acrylic nanofibers were prepared from alkaline hydrolysis of hydrophobic polyacrylonitrile (PAN) nanofibers. Water contact angle, pore volume, and liquid retention capacity of PAN nanofibrous membranes were measured to determine their dependence on hydrolysis parameters such as base concentration, temperature, and time. Vertical water retention capacity of hydrolyzed PAN nanofibrous membrane could reach as large as 200 times of that of original membrane. Fiber twinning in post-hydrolyzed PAN nanofibrous membrane. [source]

Electrospun PEG,PLA nanofibrous membrane for sustained release of hydrophilic antibiotics

JOURNAL OF APPLIED POLYMER SCIENCE, Issue 1 2010
Xiuling Xu
Abstract Reported in this study is the successful incorporation of a hydrophilic antibiotic drug, tetracycline hydrochloride (TCH), into electrospun PEG,PLA nanofibrous membrane without loss of its bioactivity. Degradation behavior of the copolymer was studied in vitro. Release behavior of TCH from the electrospun membrane and antimicrobial effects of the TCH-loaded membrane against Staphylococcus aureus culture were investigated. The medicated nanofibrous membrane demonstrated sustained release of TCH over 6 days and was found to be effective in inhibiting growth of S. aureus. In addition, increasing the antibiotic drug content in the electrospun membranes was found to enhance the anti-bacterial effectiveness of the medicated fiber mats. And the combination of mechanical barriers provided by the electrospun biodegradable nanofibrous membranes and their capability of local sustained delivery of antibiotics made these membranes more useful in biomedical applications, particularly as new wound dressings for ulcers caused by diabetes or other diseases, and to provide a better means of treatment for these malignant wounds and ulcers. © 2010 Wiley Periodicals, Inc. J Appl Polym Sci, 2010 [source]

Preparation of Water-Absorbing Polyacrylonitrile Nanofibrous Membrane

MACROMOLECULAR RAPID COMMUNICATIONS, Issue 2 2006
Haiqing Liu
Abstract Summary: Hydrophilic acrylic nanofibers were prepared from alkaline hydrolysis of hydrophobic polyacrylonitrile (PAN) nanofibers. Water contact angle, pore volume, and liquid retention capacity of PAN nanofibrous membranes were measured to determine their dependence on hydrolysis parameters such as base concentration, temperature, and time. Vertical water retention capacity of hydrolyzed PAN nanofibrous membrane could reach as large as 200 times of that of original membrane. Fiber twinning in post-hydrolyzed PAN nanofibrous membrane. [source]

Carbon Nanotube-Adsorbed Electrospun Nanofibrous Membranes of Nylon 6

MACROMOLECULAR RAPID COMMUNICATIONS, Issue 2 2006
Hyun Suk Kim
Abstract Summary: A simple and mass-producible method was developed to densely assemble multiwalled carbon nanotubes (MWNTs) onto electrospun nylon 6 nanofibrous membranes. The process consists of dispersing the acid-treated MWNTs in surfactant solutions or organic solvents, and dipping the nanofibrous membranes in the resulting dispersion for only 60 seconds, followed by the extraction of the surfactants in pure water and drying. The conductivity of the MWNT-adsorbed nanofibrous membranes ranges from 2.2,×,10,2 to 1.5,×,10,1 S,·,cm,1, as determined by the four probe method, which implies that the MWNTs are adsorbed uniformly and densely along the nanofibrous membranes. Furthermore, the results suggest that there is a strong interaction between the acid-treated MWNTs and nylon 6. We also investigate the amount of MWNTs present in the membranes using thermogravimetric analysis. SEM images of the non-woven fibrous nylon 6 membranes after dip-coating in a dispersion of the MWNTs in surfactant-containing water. [source]