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Myeloid Sarcoma (myeloid + sarcoma)

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Medical Sciences100%

Selected Abstracts

Mass-forming extramedullary hematopoiesis diagnosed by fine-needle aspiration cytology

DIAGNOSTIC CYTOPATHOLOGY, Issue 12 2006
Maria Luisa C. Policarpio-Nicolas M.D.
Abstract Extramedullary hematopoiesis (EMH) is usually a microscopic finding. However, it may present as a mass-forming lesion making it amenable to fine-needle aspiration biopsy (FNAB). When mass-forming EMH occurs, it can simulate a neoplasm clinically and radiologically. Additionally, the megakaryocytes can mimic malignant neoplastic cells, particularly if EMH is not a considered diagnosis. We report six cases of mass-forming EMH diagnosed by FNAB and evaluate the utility of FNAB in diagnosing EMH. Four patients had prior diagnoses of hematologic disorders, one patient had malignant mastocytosis who presented with lymphadenopathy and one patient had a history of carcinoma. The patients' ages ranged from 46 to 78 yr with an equal sex distribution. Aspirate smears showed trilineage hematopoiesis. The cytomorphologic differential diagnosis included metastatic carcinoma, Hodgkin lymphoma and myeloid sarcoma. No special stains were necessary due to the classic cytologic findings and prior hematologic history. Diagn. Cytopathol. 2006; 34:807,811. © 2006 Wiley-Liss, Inc. [source]

Acute promyelocytic leukaemia presenting with a myeloid sarcoma of the tongue

BRITISH JOURNAL OF HAEMATOLOGY, Issue 5 2008
S. Mohamedbhai
No abstract is available for this article. [source]

Right atrial myeloid sarcoma causing superior vena cava syndrome

BRITISH JOURNAL OF HAEMATOLOGY, Issue 2 2008
Darko Antic
No abstract is available for this article. [source]

Disseminated extramedullary myeloid tumor of the gallbladder without involvement of the bone marrow

AMERICAN JOURNAL OF HEMATOLOGY, Issue 1 2007
Angela N. Bartley
Abstract Extramedullary myeloid tumors (myeloid sarcomas) are rare neoplasms that are composed of myeloid precursors. They usually arise concurrently with a diagnosis of acute myeloid leukemia, chronic myeloid leukemia, or other myeloproliferative disorders. They may also indicate relapsing disease in a patient with a prior history of leukemia or myeloproliferative disorder. We present our findings of a 63-year-old female diagnosed with extramedullary myeloid tumor first presenting in the gallbladder. She subsequently developed respiratory failure; pre- and postmortem bone marrow studies were negative for leukemia by morphology, flow cytometry, and karyotypic analysis. However, the myeloid neoplasm was disseminated throughout most of her remaining organs. Immunohistochemical stains of the cells indicated a neoplasm of myelomonocytic derivation (CD4, CD43, CD45, CD68, myeloperoxidase, and lysozyme positive). To our knowledge, this is the first report of an extramedullary myeloid neoplasm of the gallbladder with disseminated disease without involvement of the bone marrow. Am. J. Hematol., 2006. © Wiley-Liss, Inc. [source]